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Dr Anne Conibear
Dr

Anne Conibear

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Phone: 
+61 7 336 51738

Overview

Background

During my postgraduate studies and postdoctoral fellowship, I gained experience in a wide range of chemical biology techniques as well as in initiating and managing collaborations. Building on a background in chemistry and biochemistry, I developed my skills in peptide chemistry and NMR spectroscopy during my PhD in Australia, synthesizing a variety of disulfide-rich cyclic peptides and elucidating their structures and dynamics by NMR spectroscopy. I have gained further experience in protein chemistry, solid phase peptide synthesis and protein ligations during my postdoctoral fellowship in Vienna, collaborating with Syntab Therapeutics on a project involving synthesis and development of synthetic antibodies for cancer therapy. I have recently taken up a UQ Development Fellowship to establish my independent research area in synthesis and structural biology of posttranslationally modified proteins.

Availability

Dr Anne Conibear is:
Available for supervision
Media expert

Qualifications

  • Doctor of Philosophy, The University of Queensland

Research interests

  • Understanding the role of posttranslational modifications in protein structure and function

    I aim to understand how proteins are regulated by chemical on/off switches - post-translational modifications (PTMs). I use protein chemical synthesis and semi-synthesis to provide access to post-translationally modified proteins for structural biology. The outcome will be new atomic resolution knowledge of how cells use chemical switches to respond to their environments and understanding of how fundamental life processes are controlled.

Works

Search Professor Anne Conibear’s works on UQ eSpace

42 works between 2010 and 2024

41 - 42 of 42 works

2011

Journal Article

Synthesis and evaluation of phosphonated N-heteroarylcarboxamides as DOXP-reductoisomerase (DXR) inhibitors

Bodin, Taryn, Conibear, Anne C., Blatch, Gregory L., Lobb, Kevin A. and Kaye, Perry T. (2011). Synthesis and evaluation of phosphonated N-heteroarylcarboxamides as DOXP-reductoisomerase (DXR) inhibitors. Bioorganic and Medicinal Chemistry, 19 (3), 1321-1327. doi: 10.1016/j.bmc.2010.11.062

Synthesis and evaluation of phosphonated N-heteroarylcarboxamides as DOXP-reductoisomerase (DXR) inhibitors

2010

Journal Article

P-31 NMR kinetic study of the tandem cleavage of phosphonate esters by bromotrimethylsilane

Conibear, Anne C., Lobb, Kevin A. and Kaye, Perry T. (2010). P-31 NMR kinetic study of the tandem cleavage of phosphonate esters by bromotrimethylsilane. Tetrahedron, 66 (43), 8446-8449. doi: 10.1016/j.tet.2010.08.058

P-31 NMR kinetic study of the tandem cleavage of phosphonate esters by bromotrimethylsilane

Funding

Past funding

  • 2022
    Australian Peptide Display Facility (ARC LIEF administered by University of Sydney)
    University of Sydney
    Open grant
  • 2020 - 2021
    Decorated venom: Exploring the role of cone snail venom modifications
    UQ Early Career Researcher
    Open grant
  • 2019 - 2022
    Investigating the role of posttranslational modifications on protein structure and function using selective and segmental isotope labelling
    CIL Research Grant Program
    Open grant
  • 2019 - 2021
    Insights into protein modifications by NMR
    UQ Development Fellowships
    Open grant

Supervision

Availability

Dr Anne Conibear is:
Available for supervision

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Media

Enquiries

Contact Dr Anne Conibear directly for media enquiries about:

  • nuclear magnetic resonance
  • peptides
  • protein modifications
  • proteins
  • structural biology

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