
Overview
Background
Emeritus Professor Mark Smithers is a surgical oncologist who specialises in surgery for oesophago-gastric diseases, melanoma, advanced skin cancer and soft tissue sarcoma. He was the Director of the Upper GI and Soft Tissue Unit at the Princess Alexandra Hospital, in Brisbane, Australia from 1998 - 2023. Commencing his academic career with the University of Queensland in 1987, he progressed to be the Mayne Chair in Surgery and head of the Academy of Surgery. He is the second University of Queensland Medical graduate to be appointed to this role. His research has been focussed on the development and assessment of outcomes from minimally invasive upper GI surgery, and trials assessing the role of perioperative multidisciplinary therapy for esophageal and gastric cancer. As well he has led, or been involved with, clinical trials from phase I to III, for all stages of melanoma through his role as the Chair of the Queensland Melanoma Project. More recently he has been involved with the assessment of access to, and outcomes from, surgery for cancer in Queensland, Australia.
He has overseen the administration and development of the surgery curriculum, and the teaching, in the Academy of Surgery, in the UQ Faculty of Medicine. He was on a number of committees relevant to the implementation of the UQ MD design course. He has held various leadership and committee roles with the Royal Australasian College of Surgeons, as well as leadership roles, including the Presidency, in the Australian and New Zealand Oesophago Gastric Surgeons Association. He has also been on the committees of international organisations related to oesophageal and gastric surgery. He has published 250 articles, eight book chapters, and has been on the editorial board of a number of surgical journals.
He has been recognised for his clinical and academic roles by the award of Member of the Order of Australia (AM). The citation reads, "for service to medicine in the fields of gastro-intestinal and melanoma surgery, to medical education and to professional organisations". The Royal Australasian College of Surgeons awarded him the Sir Hugh Devine medal, for services to surgery and the community. This is the College’s highest honour. Internationally, he has been awarded an honorary fellowship of the Royal College of Surgeons of Edinburgh and recently, in the United States, he was elected as an Honarary Fellow of the American Surgical Association.
Availability
- Professor Mark Smithers is:
- Not available for supervision
- Media expert
Fields of research
Qualifications
- Bachelor of Medicine and Surgery and Medical Science, The University of Queensland
- Honorary Fellow, American Surgical Association, American Surgical Association
- Fellow, Royal Australasian College of Surgeons, Royal Australasian College of Surgeons
- Fellow, Royal College of Surgeons of Edinburgh, Royal College of Surgeons of Edinburgh
- Fellow, Royal College of Surgeons of England, Royal College of Surgeons of England
Research interests
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Cutaneous Melanoma
epidemiology, public health issues and management of all stages
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Management of Oesophageal and Gastric Cancer
Investigation and management of benign and malignant diseases of the oesophagus and the stomach.
Works
Search Professor Mark Smithers’s works on UQ eSpace
2013
Journal Article
Patients undergoing lymphadenectomy for Stage III melanomas of known or unknown primary site do not differ in outcome
Hughes, Maria Celia, Wright, Annaliesa, Barbour, Andrew, Thomas, Janine, Smithers, B. Mark, Green, Adele C. and Khosrotehrani, Kiarash (2013). Patients undergoing lymphadenectomy for Stage III melanomas of known or unknown primary site do not differ in outcome. International Journal of Cancer, 133 (12), 3000-3007. doi: 10.1002/ijc.28318
2013
Conference Publication
The Volume-Outcome Relationship in Cancer Surgery - Do Rural Patients Have a Choice?
Smithers, Mark, Zarate, Dannie, Harden, Hazel, Colquist, Shoni and Walpole, Euan (2013). The Volume-Outcome Relationship in Cancer Surgery - Do Rural Patients Have a Choice?. HOBOKEN: WILEY-BLACKWELL.
2013
Journal Article
Stage III melanoma in the axilla: patterns of regional recurrence after surgery with and without adjuvant radiation therapy
Pinkham, Mark B., Foote, Matthew C., Burmeister, Elizabeth, Thomas, Janine, Meakin, Janelle, Smithers, B. Mark and Burmeister, Bryan H. (2013). Stage III melanoma in the axilla: patterns of regional recurrence after surgery with and without adjuvant radiation therapy. International Journal of Radiation: Oncology - Biology - Physics, 86 (4), 702-708. doi: 10.1016/j.ijrobp.2013.03.019
2013
Conference Publication
Australian Multi-Center Study of Isolated Limb Infusion Chemotherapy for Melanoma: Experience Outside of the Sydney Melanoma Unit
Kroon, H., Coventry, B., Giles, M., Henderson, M., Serpell, J. and Smithers, M. (2013). Australian Multi-Center Study of Isolated Limb Infusion Chemotherapy for Melanoma: Experience Outside of the Sydney Melanoma Unit. HOBOKEN: WILEY-BLACKWELL.
2013
Journal Article
Surgery and the management of cutaneous melanoma
Allan, C. and Smithers, B. M. (2013). Surgery and the management of cutaneous melanoma. British Journal of Surgery, 100 (3), 313-315. doi: 10.1002/bjs.9054
2013
Book Chapter
Esophagus carcinoma surveillance counter: Australia
Smithers, Bernard Mark, Thomas, Janine M. and Burmeister, Bryan H. (2013). Esophagus carcinoma surveillance counter: Australia. Patient Surveillance after Cancer Treatment. (pp. 97-100) edited by Frank Johnson, Yoshihiko Maehara, George P. Browman, Julie A. Margenthaler, Riccardo A. Audisio, John F. Thompson, David Y. Johnson, Craig C. Earle and Katerine S. Virgo. New York, United States: Humana Press. doi: 10.1007/978-1-60327-969-7_17
2013
Conference Publication
Pilot multi-marker analysis to evaluate prognosis in stage Ib and II melanomas
Rowe, C. J., Rodero, M., Malt, M., Smithers, M., Green, A. and Khosrotehrani, K. (2013). Pilot multi-marker analysis to evaluate prognosis in stage Ib and II melanomas. The Australasian College of Dermatologists 46th Annual Scientific Meeting, Sydney, NSW Australia, 19 – 22 May 2013. Richmond, VIC Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/ajd.12051
2013
Conference Publication
Sequential transcriptional changes dictate safe and effective antigen-specific immunotherapy of autoimmune disease
Burton, B. R., Britton, G. J., Fang, H., Verhagen, J., Smithers, B., Sabatos-Peyton, C. A., Carney, L. J., Gough, J., Strobel, S. and Wraith, C. (2013). Sequential transcriptional changes dictate safe and effective antigen-specific immunotherapy of autoimmune disease. Annual Congress of the British-Society-for-Immunology, Liverpool England, Dec 02-05, 2013. West Sussex United Kingdom: Wiley-Blackwell Publishing. doi: 10.1111/imm.12217
2013
Conference Publication
Survival and recurrence outcome in patients with melanomas of unknown primary invading lymph nodes
Wright, A., Hughes, M., Siskind, V., Smithers, M., Thomas, J., Green, A. and Khosrotehrani, K. (2013). Survival and recurrence outcome in patients with melanomas of unknown primary invading lymph nodes. The Australasian College of Dermatologists 46th Annual Scientific Meeting, Sydney, NSW Australia, 19 – 22 May 2013. Richmond, VIC Australia: Wiley-Blackwell. doi: 10.1111/ajd.12051
2013
Conference Publication
Adjuvant radiotherapy after lymphadenectomy in melanoma patients: Final results of an intergroup randomized trial (ANZMTG 0.1.02/TROG 02.01)
Henderson, Michael A., Burmeister, Bryan, Ainslie, Jill, Fisher, Richard, Di Iulio, Julianna, Smithers, Bernard Mark, Hong, Angela, Shannon, Kerwin F., Scolyer, Richard A., Carruthers, Scott, Coventry, Brendon J., Babington, Scott, Duprat, Joao, Hoekstra, Harald J. and Thompson, John F. (2013). Adjuvant radiotherapy after lymphadenectomy in melanoma patients: Final results of an intergroup randomized trial (ANZMTG 0.1.02/TROG 02.01). 49th Annual Meeting of the American-Society-of-Clinical-Oncology (ASCO), Chicago IL United States, May 31-Jun 04, 2013. United States: American Society of Clinical Oncology.
2013
Journal Article
Neoadjuvant Chemotherapy or Chemoradiotherapy for Locally Advanced Esophageal Cancer
Smithers, B. Mark and Thomson, Iain (2013). Neoadjuvant Chemotherapy or Chemoradiotherapy for Locally Advanced Esophageal Cancer. Thoracic Surgery Clinics, 23 (4), 509-523. doi: 10.1016/j.thorsurg.2013.07.005
2013
Conference Publication
Locoregional disease control in metastatic melanoma: Exploratory analysis from phase 2 testing of intralesional rose bengal
Agarwala, S., Thompson, J. F., Smithers, B. M., Ross, M. I., Coventry, B. J., Minor, D. R., Scoggins, C. R., Singer, J. M. and Wachter, E. A. (2013). Locoregional disease control in metastatic melanoma: Exploratory analysis from phase 2 testing of intralesional rose bengal. 17th ECCO / 38th ESMO / 32nd ESTRO European Cancer Congress on Reinforcing Multidisciplinarity, Amsterdam Netherlands, Sep 27-Oct 01, 2013. Oxford United Kingdom: Pergamon. doi: 10.1016/S0959-8049(13)70065-0
2013
Journal Article
Impact of postoperative morbidity on long-term survival after oesophagectomy
Hii, M. W., Smithers, B. M., Gotley, D. C., Thomas, J. M., Thomson, I., Martin, I. and Barbour, A. P. (2013). Impact of postoperative morbidity on long-term survival after oesophagectomy. British Journal of Surgery, 100 (1), 95-104. doi: 10.1002/bjs.8973
2012
Journal Article
Prevalence and determinants of frequent gastroesophageal reflux symptoms in the Australian community
Pandeya, N., Green, A. C., Whiteman, D. C., The Australian Cancer Study and Smithers, B. M. (2012). Prevalence and determinants of frequent gastroesophageal reflux symptoms in the Australian community. Diseases of the Esophagus, 25 (7), 573-583. doi: 10.1111/j.1442-2050.2011.01287.x
2012
Journal Article
Metastasectomy for distant metastatic melanoma: analysis of data from the first multicenter selective lymphadenectomy trial (MSLT-I)
Howard, J. Harrison, Thompson, John F., Mozzillo, Nicola, Nieweg, Omgo E., Hoekstra, Harald J., Roses, Daniel F., Sondak, Vernon K., Reintgen, Douglas S., Kashani-Sabet, Mohammed, Karakousis, Constantine P., Coventry, Brendon J., Kraybill, William G., Smithers, B. Mark, Elashoff, Robert, Stern, Stacey L., Cochran, Alistair J., Faries, Mark B. and Morton, Donald L. (2012). Metastasectomy for distant metastatic melanoma: analysis of data from the first multicenter selective lymphadenectomy trial (MSLT-I). Annals of Surgical Oncology, 19 (8), 2547-2555. doi: 10.1245/s10434-012-2398-z
2012
Journal Article
Modeling the cost-effectiveness of strategies for treating esophageal adenocarcinoma and high-grade dysplasia
Gordon, Louisa G., Hirst, Nicholas G., Mayne, George C., Watson, David I., Bright, Timothy, Cai, Wang, Barbour, Andrew P., Smithers, Bernard M., Whiteman, David C. and Eckermann, Simon (2012). Modeling the cost-effectiveness of strategies for treating esophageal adenocarcinoma and high-grade dysplasia. Journal of Gastrointestinal Surgery, 16 (8), 1451-1461. doi: 10.1007/s11605-012-1911-9
2012
Journal Article
Adjuvant radiotherapy versus observation alone for patients at risk of lymph-node field relapse after therapeutic lymphadenectomy for melanoma: a randomised trial
Burmeister, Bryan H., Henderson, Michael A., Ainslie, Jill, Fisher, Richard, Di Iulio, Juliana, Smithers, B. Mark, Hong, Angela, Shannon, Kerwin, Scolyer, Richard A., Carruthers, Scott, Coventry, Brendon J., Babington, Scott, Duprat, Joao, Hoekstra, Harald J. and Thompson, John F. (2012). Adjuvant radiotherapy versus observation alone for patients at risk of lymph-node field relapse after therapeutic lymphadenectomy for melanoma: a randomised trial. Lancet Oncology, 13 (6), 589-597. doi: 10.1016/S1470-2045(12)70138-9
2012
Journal Article
An innovative approach for locally advanced stage III cutaneous melanoma: radiotherapy, followed by nodal dissection
Foote, Matthew, Burmeister, Bryan, Dwyer, Patrick, Burmeister, Elizabeth, Lambie, Duncan, Allan, Christopher, Barbour, Andrew, Bayley, Gerard, Pullar, Andrew, Meakin, Janelle, Thomas, Janine and Smithers, Mark (2012). An innovative approach for locally advanced stage III cutaneous melanoma: radiotherapy, followed by nodal dissection. Melanoma Research, 22 (3), 257-262. doi: 10.1097/CMR.0b013e3283531335
2012
Conference Publication
TOPGEAR: An international randomized phase III trial of preoperative chemoradiotherapy versus preoperative chemotherapy for resectable gastric cancer (AGITG/TROG/EORTC/NCIC CTG)
Leong, Trevor, Smithers, Mark, Michael, Michael, Gebski, Val, Boussioutas, Alex, Miller, Danielle, Zalcberg, John Raymond, Wong, Rebecca and Haustermans, Karin (2012). TOPGEAR: An international randomized phase III trial of preoperative chemoradiotherapy versus preoperative chemotherapy for resectable gastric cancer (AGITG/TROG/EORTC/NCIC CTG). 48th Annual Meeting of the American-Society-of-Clinical-Oncology (ASCO), Chicago Il, Jun 01-06, 2012. ALEXANDRIA: AMER SOC CLINICAL ONCOLOGY.
2012
Journal Article
Population-based 20-year survival among people diagnosed with thin melanomas in Queensland, Australia
Green, Adele C., Baade, Peter, Coory, Michael, Aitken, Joanne F. and Smithers, Mark (2012). Population-based 20-year survival among people diagnosed with thin melanomas in Queensland, Australia. Journal of Clinical Oncology, 30 (13), 1462-1467. doi: 10.1200/JCO.2011.38.8561
Supervision
Availability
- Professor Mark Smithers is:
- Not available for supervision
Supervision history
Current supervision
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Master Philosophy
Retroperitoneal sarcoma: Impact of the patterns of care on patient outcomes in Queensland.
Principal Advisor
Other advisors: Professor Andrew Barbour
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Master Philosophy
Trends in the regional nodal management of cutaneous melanoma.
Principal Advisor
Other advisors: Professor Peter Soyer
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Master Philosophy
Factors Influencing Anastomotic Complications after Oesophagectomy
Associate Advisor
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Doctor Philosophy
Utilising the Multi-Disciplinary Resources at Tertiary Centres to Improve Outcomes from Pancreatic Cancer
Associate Advisor
Other advisors: Dr David Cavallucci
Completed supervision
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2020
Master Philosophy
An assessment of the impacts of centralising complex upper-gastrointestinal surgery in Queensland
Principal Advisor
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2024
Master Philosophy
In vivo Magnetic Resonance Spectroscopy (MRS) with 2-Dimensional (2D) COrrelated Spectroscopy (COSY) applied to breast cancer
Associate Advisor
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2020
Doctor Philosophy
Natural history of high-risk cutaneous primary melanoma and risk factors for disease progression
Associate Advisor
Other advisors: Professor Kiarash Khosrotehrani
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2020
Doctor Philosophy
An evaluation of the role of locoregional treatments for the management of in-transit melanoma metastases
Associate Advisor
Other advisors: Professor Peter Soyer, Associate Professor Helmut Schaider
Media
Enquiries
Contact Professor Mark Smithers directly for media enquiries about:
- Advanced endoscopic surgery
- Cancer surgery
- Endoscopic surgery
- General surgery
- Melanoma
- Surgery - cancer
- Surgery - oesophageal, gastric cancer
- Surgery - upper GI
- Upper GI surgery
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