
Overview
Background
Emeritus Professor Mark Smithers is a surgical oncologist who specialises in surgery for oesophago-gastric diseases, melanoma, advanced skin cancer and soft tissue sarcoma. He was the Director of the Upper GI and Soft Tissue Unit at the Princess Alexandra Hospital, in Brisbane, Australia from 1998 - 2023. Commencing his academic career with the University of Queensland in 1987, he progressed to be the Mayne Chair in Surgery and head of the Academy of Surgery. He is the second University of Queensland Medical graduate to be appointed to this role. His research has been focussed on the development and assessment of outcomes from minimally invasive upper GI surgery, and trials assessing the role of perioperative multidisciplinary therapy for esophageal and gastric cancer. As well he has led, or been involved with, clinical trials from phase I to III, for all stages of melanoma through his role as the Chair of the Queensland Melanoma Project. More recently he has been involved with the assessment of access to, and outcomes from, surgery for cancer in Queensland, Australia.
He has overseen the administration and development of the surgery curriculum, and the teaching, in the Academy of Surgery, in the UQ Faculty of Medicine. He was on a number of committees relevant to the implementation of the UQ MD design course. He has held various leadership and committee roles with the Royal Australasian College of Surgeons, as well as leadership roles, including the Presidency, in the Australian and New Zealand Oesophago Gastric Surgeons Association. He has also been on the committees of international organisations related to oesophageal and gastric surgery. He has published 250 articles, eight book chapters, and has been on the editorial board of a number of surgical journals.
He has been recognised for his clinical and academic roles by the award of Member of the Order of Australia (AM). The citation reads, "for service to medicine in the fields of gastro-intestinal and melanoma surgery, to medical education and to professional organisations". The Royal Australasian College of Surgeons awarded him the Sir Hugh Devine medal, for services to surgery and the community. This is the College’s highest honour. Internationally, he has been awarded an honorary fellowship of the Royal College of Surgeons of Edinburgh and recently, in the United States, he was elected as an Honarary Fellow of the American Surgical Association.
Availability
- Professor Mark Smithers is:
- Not available for supervision
- Media expert
Fields of research
Qualifications
- Bachelor of Medicine and Surgery and Medical Science, The University of Queensland
- Honorary Fellow, American Surgical Association, American Surgical Association
- Fellow, Royal Australasian College of Surgeons, Royal Australasian College of Surgeons
- Fellow, Royal College of Surgeons of Edinburgh, Royal College of Surgeons of Edinburgh
- Fellow, Royal College of Surgeons of England, Royal College of Surgeons of England
Research interests
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Cutaneous Melanoma
epidemiology, public health issues and management of all stages
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Management of Oesophageal and Gastric Cancer
Investigation and management of benign and malignant diseases of the oesophagus and the stomach.
Works
Search Professor Mark Smithers’s works on UQ eSpace
2017
Journal Article
Diphenylcyclopropenone for the treatment of cutaneous in-transit melanoma metastases - results of a prospective, non-randomized, single-centre study
Read, T., Webber, S., Tan, J., Wagels, M., Schaider, H., Soyer, H. P. and Smithers, B. M. (2017). Diphenylcyclopropenone for the treatment of cutaneous in-transit melanoma metastases - results of a prospective, non-randomized, single-centre study. Journal of the European Academy of Dermatology and Venereology, 31 (12), 2030-2037. doi: 10.1111/jdv.14422
2017
Journal Article
Completion dissection or observation for sentinel-node metastasis in melanoma
Faries, M. B., Thompson, J. F., Cochran, A. J., Andtbacka, R. H., Mozzillo, N., Zager, J. S., Jahkola, T., Bowles, T. L., Testori, A., Beitsch, P. D., Hoekstra, H. J., Moncrieff, M., Ingvar, C., Wouters, M. W. J. M., Sabel, M. S., Levine, E. A., Agnese, D., Henderson, M., Dummer, R., Rossi, C. R., Neves, R. I., Trocha, S. D., Wright, F., Byrd, D. R., Matter, M., Hsueh, E., MacKenzie-Ross, A., Johnson, D. B., Terheyden, P. ... Elashoff, R. M. (2017). Completion dissection or observation for sentinel-node metastasis in melanoma. New England Journal of Medicine, 376 (23), 2211-2222. doi: 10.1056/NEJMoa1613210
2017
Journal Article
Use of support services in a sample of patients with high-risk primary melanomas in urban, regional and rural Queensland
von Schuckmann, Lena A., Smithers, Bernhard M., Khosrotehrani, Kiarash, Beesley, Vanessa L., van der Pols, Jolieke C., Hughes, Maria B. and Green, Adele C. (2017). Use of support services in a sample of patients with high-risk primary melanomas in urban, regional and rural Queensland. Australian and New Zealand Journal of Public Health, 41 (3), 315-319. doi: 10.1111/1753-6405.12662
2017
Journal Article
TOPGEAR: A Randomized, Phase III Trial of Perioperative ECF Chemotherapy with or Without Preoperative Chemoradiation for Resectable Gastric Cancer: Interim Results from an International, Intergroup Trial of the AGITG, TROG, EORTC and CCTG
Leong, Trevor, Smithers, B. Mark, Haustermans, Karin, Michael, Michael, Gebski, Val, Miller, Danielle, Zalcberg, John, Boussioutas, Alex, Findlay, Michael, O'Connell, Rachel L., Verghis, Jaclyn, Willis, David, Kron, Tomas, Crain, Melissa, Murray, William K., Lordick, Florian, Swallow, Carol, Darling, Gail, Simes, John and Wong, Rebecca (2017). TOPGEAR: A Randomized, Phase III Trial of Perioperative ECF Chemotherapy with or Without Preoperative Chemoradiation for Resectable Gastric Cancer: Interim Results from an International, Intergroup Trial of the AGITG, TROG, EORTC and CCTG. Annals of Surgical Oncology, 24 (8), 2252-2258. doi: 10.1245/s10434-017-5830-6
2017
Journal Article
Primary cutaneous melanoma of the scalp: Patterns of recurrence
Sparks, David S., Read, Tavis, Lonne, Michael, Barbour, Andrew P., Wagels, Michael, Bayley, Gerard J. and Smithers, B. Mark (2017). Primary cutaneous melanoma of the scalp: Patterns of recurrence. Journal of Surgical Oncology, 115 (4), 449-454. doi: 10.1002/jso.24535
2017
Journal Article
GSTP1 does not modify MC1R effects on melanoma risk
Daley, G. M., Duffy, D. L., Pflugfelder, A., Jagirdar, K., Lee, K. J., Yong, X. L., Eigentler, T. K., Weide, B., Smithers, B. M., Martin, N. G., Garbe, C., Soyer, H. P. and Sturm, R. A. (2017). GSTP1 does not modify MC1R effects on melanoma risk. Experimental Dermatology, 26 (8), 730-733. doi: 10.1111/exd.13114
2017
Journal Article
Results of a phase II, open-label, non-comparative study of intralesional PV-10 followed by radiotherapy for the treatment of in-transit or metastatic melanoma
Foote, Matthew, Read, Tavis, Thomas, Janine, Wagels, Michael, Burmeister, Bryan and Smithers, B. Mark (2017). Results of a phase II, open-label, non-comparative study of intralesional PV-10 followed by radiotherapy for the treatment of in-transit or metastatic melanoma. Journal of Surgical Oncology, 115 (7), 891-897. doi: 10.1002/jso.24580
2017
Conference Publication
Long-term health-related quality of life following esophagectomy: A nonrandomized comparison of thoracoscopically assisted and open surgery
Barbour, Andrew P., McCormack, Orla M. , Baker, Peter J., Hirst, Jodi, Krause, Lutz, Brosda, Sandra, Thomas, Janine M., Blazeby, Jane M., Thomson, Iain G., Gotley, David C. and Smithers, Bernard M. (2017). Long-term health-related quality of life following esophagectomy: A nonrandomized comparison of thoracoscopically assisted and open surgery. Philadelphia, PA United States: Lippincott Williams & Wilkins. doi: 10.1097/SLA.0000000000001899
2017
Conference Publication
Outcomes of complex cancer surgery in Queensland
Smithers, Mark, Theile, David E., Philpot, Shoni, Guan, Tracey and Dunn, Nathan (2017). Outcomes of complex cancer surgery in Queensland. COSA's 44th Annual Scientific Meeting, Sydney, NSW Australia, 13-15 November 2017. Chichester, West Sussex United Kingdom: Wiley-Blackwell. doi: 10.1111/ajco.12798
2017
Conference Publication
Outcome predictors in median arcuate ligament syndrome
Ho, Kelvin Kam Fai, Walker, Philip, Smithers, B. Mark, Foster, Wallace, Nathanson, Leslie, O'Rourke, Nicholas, Shaw, Ian and McGahan, Timothy (2017). Outcome predictors in median arcuate ligament syndrome. Royal Australasian College of Surgeons Annual Scientific Congress and the Australia and New Zealand Society for Vascular Surgery Annual Scientific Meeting, Canberra, Australia, 11-13 October 2014. Philadelphia, PA United States: Mosby. doi: 10.1016/j.jvs.2016.11.040
2016
Journal Article
Trans tracheal approach to the oesophagus: case report
Lynch, Angelica, Perry, Chris, Smithers, Bernard Mark, Gundelach, Raefe and Rowe, Daniel (2016). Trans tracheal approach to the oesophagus: case report. Archives of Otolaryngology and Rhinology, 077-078. doi: 10.17352/2455-1759.000030
2016
Journal Article
Recommendations for clinical staging (cTNM) of cancer of the esophagus and esophagogastric junction for the 8th edition AJCC/UICC staging manuals
Rice, Thomas W., Ishwaran, Hemant, Blackstone, Eugene H., Hofstetter, Wayne L., Kelsen, David P., Apperson-Hansen, Carolyn, Worldwide Esophageal Cancer Collaboration Investigators and Smithers, Bernard (2016). Recommendations for clinical staging (cTNM) of cancer of the esophagus and esophagogastric junction for the 8th edition AJCC/UICC staging manuals. Diseases of the Esophagus, 29 (8), 913-919. doi: 10.1111/dote.12540
2016
Journal Article
Identification of the CIMP-like subtype and aberrant methylation of members of the chromosomal segregation and spindle assembly pathways in esophageal adenocarcinoma
Krause, Lutz, Nones, Katia , Loffler, Kelly A., Nancarrow, Derek, Oey, Harald , Tang, Yue Hang, Wayte, Nicola J., Patch, Ann Marie, Patel, Kalpana , Brosda, Sandra, Manning, Suzanne, Lampe, Guy, Clouston, Andrew, Thomas, Janine, Stoye, Jens, Hussey, Damian J., Watson, David I., Lord, Reginald V., Phillips, Wayne A., Gotley, David, Smithers, B. Mark, Whiteman, David C., Hayward, Nicholas K., Grimmond, Sean M., Waddell, Nicola and Barbour, Andrew P. (2016). Identification of the CIMP-like subtype and aberrant methylation of members of the chromosomal segregation and spindle assembly pathways in esophageal adenocarcinoma. Carcinogenesis, 37 (4), 356-365. doi: 10.1093/carcin/bgw018
2016
Journal Article
Worldwide esophageal cancer collaboration: neoadjuvant pathologic staging data
Rice, T. W., Lerut, T. E. M. R., Orringer, M. B., Chen, L. -Q., Hofstetter, W. L., Smithers, B. M., Rusch, V. W., van Lanschot, J., Chen, K. N., Davies, A. R., D'Journo, X. B., Kesler, K. A., Luketich, J. D., Ferguson, M. K., Rasanen, J. V., van Hillegersberg, R., Fang, W., Durand, L., Allum, W. H., Cecconello, I., Cerfolio, R. J., Pera, M., Griffin, S. M., Burger, R., Liu, J. -F., Allen, M. S., Law, S., Watson, T. J., Darling, G. E. ... Blackstone, E. H. (2016). Worldwide esophageal cancer collaboration: neoadjuvant pathologic staging data. Diseases of the Esophagus, 29 (7), 715-723. doi: 10.1111/dote.12513
2016
Journal Article
Worldwide esophageal cancer collaboration: clinical staging data
Rice, T. W., Apperson-Hansen, C., DiPaola, L. M., Semple, M. E., Lerut, T. E. M. R., Orringer, M. B., Chen, L. -Q., Hofstetter, W. L., Smithers, B. M., Rusch, V. W., Wijnhoven, B. P. L., Chen, K. N., Davies, A. R., D'Journo, X. B., Kesler, K. A., Luketich, J. D., Ferguson, M. K., Rasanen, J. V., van Hillegersberg, R., Fang, W., Durand, L., Allum, W. H., Cecconello, I., Cerfolio, R. J., Pera, M., Griffin, S. M., Burger, R., Liu, J. -F., Allen, M. S. ... Blackstone, E. H. (2016). Worldwide esophageal cancer collaboration: clinical staging data. Diseases of the Esophagus, 29 (7), 707-714. doi: 10.1111/dote.12493
2016
Journal Article
Worldwide Esophageal Cancer Collaboration: pathologic staging data
Rice, T. W., Chen, L. -Q., Hofstetter, W. L., Smithers, B. M., Rusch, V. W., Wijnhoven, B. P. L., Chen, K. L., Davies, A. R., D'Journo, X. B., Kesler, K. A., Luketich, J. D., Ferguson, M. K., Raesaenen, J. V., van Hillegersberg, R., Fang, W., Durand, L., Cecconello, I., Allum, W. H., Cerfolio, R. J., Pera, M., Griffin, S. M., Burger, R., Liu, J. -F., Allen, M. S., Law, S., Watson, T. J., Darling, G. E., Scott, W. J., Duranceau, A. ... Blackstone, E. H. (2016). Worldwide Esophageal Cancer Collaboration: pathologic staging data. Diseases of the Esophagus, 29 (7), 724-733. doi: 10.1111/dote.12520
2016
Journal Article
Variations in supportive care needs of patients after diagnosis of localised cutaneous melanoma: a 2-year follow-up study
Beesley, Vanessa L., Smithers, B. Mark, O'Rourke, Peter, Janda, Monika, Khosrotehrani, Kiarash and Green, Adèle C. (2016). Variations in supportive care needs of patients after diagnosis of localised cutaneous melanoma: a 2-year follow-up study. Supportive Care in Cancer, 25 (1), 1-10. doi: 10.1007/s00520-016-3378-9
2016
Journal Article
Molecular markers to complement sentinel node status in predicting survival in patients with high-risk locally invasive melanoma
Rowe, Casey J., Tang, Fiona, Hughes, Maria Celia B., Rodero, Mathieu P., Malt, Maryrose, Lambie, Duncan, Barbour, Andrew, Hayward, Nicholas K., Smithers, B. Mark, Green, Adele C. and Khosrotehrani, Kiarash (2016). Molecular markers to complement sentinel node status in predicting survival in patients with high-risk locally invasive melanoma. International Journal of Cancer, 139 (3), 664-672. doi: 10.1002/ijc.30085
2016
Conference Publication
Intralesional rose bengal for treatment of melanoma
Agarwala, Sanjiv S., Andtbacka, Robert Hans Ingemar, Rice, Kristen N., Ross, Merrick I., Scoggins, Charles Raben, Smithers, Bernard Mark, Whitman, Eric D. and Wachter, Eric Andrew (2016). Intralesional rose bengal for treatment of melanoma. Annual Meeting of the American-Society-of-Clinical-Oncology (ASCO), Chicago Il, Jun 03-07, 2016. ALEXANDRIA: AMER SOC CLINICAL ONCOLOGY. doi: 10.1200/JCO.2016.34.15_suppl.TPS9600
2016
Journal Article
Assessment of morbidity following regional nodal dissection in the axilla and groin for metastatic melanoma
Theodore, Jane E., Frankel, Adam J., Thomas, Janine M., Barbour, Andrew P., Bayley, Gerard J., Allan, Christopher P., Wagels, Michael and Smithers, B. Mark (2016). Assessment of morbidity following regional nodal dissection in the axilla and groin for metastatic melanoma. ANZ journal of surgery, 87 (1-2), 44-48. doi: 10.1111/ans.13526
Supervision
Availability
- Professor Mark Smithers is:
- Not available for supervision
Supervision history
Current supervision
-
Master Philosophy
Retroperitoneal sarcoma: Impact of the patterns of care on patient outcomes in Queensland.
Principal Advisor
Other advisors: Professor Andrew Barbour
-
Master Philosophy
Trends in the regional nodal management of cutaneous melanoma.
Principal Advisor
Other advisors: Professor Peter Soyer
-
Doctor Philosophy
Utilising the Multi-Disciplinary Resources at Tertiary Centres to Improve Outcomes from Pancreatic Cancer
Associate Advisor
Other advisors: Dr David Cavallucci
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Master Philosophy
Factors Influencing Anastomotic Complications after Oesophagectomy
Associate Advisor
Completed supervision
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2020
Master Philosophy
An assessment of the impacts of centralising complex upper-gastrointestinal surgery in Queensland
Principal Advisor
-
2024
Master Philosophy
In vivo Magnetic Resonance Spectroscopy (MRS) with 2-Dimensional (2D) COrrelated Spectroscopy (COSY) applied to breast cancer
Associate Advisor
-
2020
Doctor Philosophy
Natural history of high-risk cutaneous primary melanoma and risk factors for disease progression
Associate Advisor
Other advisors: Professor Kiarash Khosrotehrani
-
2020
Doctor Philosophy
An evaluation of the role of locoregional treatments for the management of in-transit melanoma metastases
Associate Advisor
Other advisors: Professor Peter Soyer, Associate Professor Helmut Schaider
Media
Enquiries
Contact Professor Mark Smithers directly for media enquiries about:
- Advanced endoscopic surgery
- Cancer surgery
- Endoscopic surgery
- General surgery
- Melanoma
- Surgery - cancer
- Surgery - oesophageal, gastric cancer
- Surgery - upper GI
- Upper GI surgery
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