Associate Professor

Robert Henderson

Email: 
Phone: 
+61 7 334 65011

Availability

Associate Professor Robert Henderson is:
Available for supervision

Search Professor Robert Henderson’s works on UQ eSpace

218 works between 1998 and 2025
All (218) Journal Article (182) Book Chapter (3) Conference Publication (31) Other Outputs (2)

21 - 40 of 218 works

2023

Journal Article

Muscle and its neuromuscular synapse – players in the pathogenesis of motor neuron disease

Noakes, Peter G., Phillips, William D., Jeffree, Rosalind L., Steyn, Frederik J., Wolvetang, Ernst J., Henderson, Rob D., McCombe, Pamela A. and Ngo, Shyuan T. (2023). Muscle and its neuromuscular synapse – players in the pathogenesis of motor neuron disease. Journal of Experimental Neurology, 4 (1), 1-5. doi: 10.33696/neurol.4.067

Muscle and its neuromuscular synapse – players in the pathogenesis of motor neuron disease

2023

Journal Article

Phenotypic variability within the desminopathies: A case series of three patients

Yeow, Dennis, Katz, Matthew, Henderson, Robert, Prasad, Sandhir, Denman, Russell, Blum, Stefan, Davis, Mark, Robertson, Thomas and McCombe, Pamela (2023). Phenotypic variability within the desminopathies: A case series of three patients. Frontiers in Neurology, 13 1110934. doi: 10.3389/fneur.2022.1110934

Phenotypic variability within the desminopathies: A case series of three patients

2023

Journal Article

Clinical and neurophysiological biomarkers of disease progression in amyotrophic lateral sclerosis

Hannaford, Andrew, Byth, Karen, Pavey, Nathan, Henderson, Robert D., Mathers, Susan, Needham, Merrilee, Schultz, David, Menon, Parvathi, Kiernan, Matthew C. and Vucic, Steve (2023). Clinical and neurophysiological biomarkers of disease progression in amyotrophic lateral sclerosis. Muscle and Nerve, 67 (1), 17-24. doi: 10.1002/mus.27736

Clinical and neurophysiological biomarkers of disease progression in amyotrophic lateral sclerosis

2023

Conference Publication

Open-Source Hypothalamic-ForniX (OSHy-X) Atlases and Segmentation Tool for 3T and 7T

Chang, Jeryn, Steyn, Frederik, Ngo, Shyuan, Henderson, Robert, Guo, Christine, Bollmann, Steffen, Fripp, Jurgen, Barth, Markus and Shaw, Thomas (2023). Open-Source Hypothalamic-ForniX (OSHy-X) Atlases and Segmentation Tool for 3T and 7T. Joint Annual Meeting ISMRM-ESMRMB & ISMRT 31st Annual Meeting, London, United Kingdom, 7-12 May 2022. Concord, CA United States: International Society for Magnetic Resonance in Medicine. doi: 10.58530/2022/3808

Open-Source Hypothalamic-ForniX (OSHy-X) Atlases and Segmentation Tool for 3T and 7T

2023

Other Outputs

Skeletal muscle and blood RNA-seq counts in motor neurone disease cases and controls

Anna Freydenzon, Allan F. McRaee, Shyuan Ngo, Naomi R. Wray, Leanne Wallace, Anjali K. Henders, Pamela A. McCombe, Robert D. Henderson and Frederik J. Steyn (2023). Skeletal muscle and blood RNA-seq counts in motor neurone disease cases and controls. The University of Queensland. (Dataset) doi: 10.48610/b722f1f

Skeletal muscle and blood RNA-seq counts in motor neurone disease cases and controls

2022

Journal Article

Age of onset and length of survival of Queensland patients with amyotrophic lateral sclerosis: with details of subjects with early onset and subjects with long survival

Nona, Robert J., Xu, Zhouwei, Robinson, Gail A., Henderson, Robert D. and McCombe, Pamela A. (2022). Age of onset and length of survival of Queensland patients with amyotrophic lateral sclerosis: with details of subjects with early onset and subjects with long survival. Neurodegenerative Diseases, 22 (3-4), 1-18. doi: 10.1159/000528875

Age of onset and length of survival of Queensland patients with amyotrophic lateral sclerosis: with details of subjects with early onset and subjects with long survival

2022

Journal Article

Lower hypothalamic volume with lower BMI is associated with shorter survival in patients with ALS

Chang, Jeryn, Shaw, Thomas B., Holdom, Cory J., McCombe, Pamela A., Henderson, Robert D., Fripp, Jurgen, Barth, Markus, Guo, Christine C., Ngo, Shyuan T. and Steyn, Frederik J. (2022). Lower hypothalamic volume with lower BMI is associated with shorter survival in patients with ALS. European Journal of Neurology, 30 (1), 57-68. doi: 10.1111/ene.15589

Lower hypothalamic volume with lower BMI is associated with shorter survival in patients with ALS

2022

Journal Article

Open-Source Hypothalamic-ForniX (OSHy-X) Atlases and Segmentation Tool for 3T and 7T

Chang, Jeryn, Steyn, Frederik, Ngo, Shyuan, Henderson, Robert, Guo, Christine, Bollmann, Steffen, Fripp, Jurgen, Barth, Markus and Shaw, Thomas (2022). Open-Source Hypothalamic-ForniX (OSHy-X) Atlases and Segmentation Tool for 3T and 7T. Journal of Open Source Software, 7 (76), 4368. doi: 10.21105/joss.04368

Open-Source Hypothalamic-ForniX (OSHy-X) Atlases and Segmentation Tool for 3T and 7T

2022

Journal Article

HLA and amyotrophic lateral sclerosis: a systematic review and meta-analysis

Nona, R. J., Greer, J. M., Henderson, R. D. and McCombe, P. A. (2022). HLA and amyotrophic lateral sclerosis: a systematic review and meta-analysis. Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 24 (1-2), 1-9. doi: 10.1080/21678421.2022.2078665

HLA and amyotrophic lateral sclerosis: a systematic review and meta-analysis

2022

Journal Article

Impaired signaling for neuromuscular synaptic maintenance is a feature of Motor Neuron Disease

Ding, Qiao, Kesavan, Kaamini, Lee, Kah Meng, Wimberger, Elyse, Robertson, Thomas, Gill, Melinder, Power, Dominique, Chang, Jeryn, Fard, Atefeh T., Mar, Jessica C., Henderson, Robert D., Heggie, Susan, McCombe, Pamela A., Jeffree, Rosalind L., Colditz, Michael J., Hilliard, Massimo A., Ng, Dominic C. H., Steyn, Frederik J., Phillips, William D., Wolvetang, Ernst J., Ngo, Shyuan T. and Noakes, Peter G. (2022). Impaired signaling for neuromuscular synaptic maintenance is a feature of Motor Neuron Disease. Acta Neuropathologica Communications, 10 (1) 61, 61. doi: 10.1186/s40478-022-01360-5

Impaired signaling for neuromuscular synaptic maintenance is a feature of Motor Neuron Disease

2022

Journal Article

Novel variants of ANO5 in two patients with limb girdle muscular dystrophy: Case Report

Katz, Matthew, Garton, Fleur C., Davis, Mark, Henderson, Robert D. and McCombe, Pamela A. (2022). Novel variants of ANO5 in two patients with limb girdle muscular dystrophy: Case Report. Frontiers in Neurology, 13 868655, 868655. doi: 10.3389/fneur.2022.868655

Novel variants of ANO5 in two patients with limb girdle muscular dystrophy: Case Report

2022

Journal Article

Genome-wide study of DNA methylation shows alterations in metabolic, inflammatory, and cholesterol pathways in ALS

Hop, Paul J., Zwamborn, Ramona A.J., Hannon, Eilis, Shireby, Gemma L., Nabais, Marta F., Walker, Emma M., van Rheenen, Wouter, van Vugt, Joke J.F.A., Dekker, Annelot M., Westeneng, Henk-Jan, Tazelaar, Gijs H.P., van Eijk, Kristel R., Moisse, Matthieu, Baird, Denis, Al Khleifat, Ahmad, Iacoangeli, Alfredo, Ticozzi, Nicola, Ratti, Antonia, Cooper-Knock, Jonathan, Morrison, Karen E., Shaw, Pamela J., Basak, A. Nazli, Chiò, Adriano, Calvo, Andrea, Moglia, Cristina, Canosa, Antonio, Brunetti, Maura, Grassano, Maurizio, Gotkine, Marc ... Brain MEND Consortium (2022). Genome-wide study of DNA methylation shows alterations in metabolic, inflammatory, and cholesterol pathways in ALS. Science Translational Medicine, 14 (633) eabj0264, 1-15. doi: 10.1126/scitranslmed.abj0264

Genome-wide study of DNA methylation shows alterations in metabolic, inflammatory, and cholesterol pathways in ALS

2022

Journal Article

Functional characterisation of the amyotrophic lateral sclerosis risk locus GPX3/TNIP1

Restuadi, Restuadi, Steyn, Frederik J., Kabashi, Edor, Ngo, Shyuan T., Cheng, Fei-Fei, Nabais, Marta F., Thompson, Mike J., Qi, Ting, Wu, Yang, Henders, Anjali K., Wallace, Leanne, Bye, Chris R., Turner, Bradley J., Ziser, Laura, Mathers, Susan, McCombe, Pamela A., Needham, Merrilee, Schultz, David, Kiernan, Matthew C., van Rheenen, Wouter, van den Berg, Leonard H., Veldink, Jan H., Ophoff, Roel, Gusev, Alexander, Zaitlen, Noah, McRae, Allan F., Henderson, Robert D., Wray, Naomi R., Giacomotto, Jean and Garton, Fleur C. (2022). Functional characterisation of the amyotrophic lateral sclerosis risk locus GPX3/TNIP1. Genome Medicine, 14 (1) 7, 7. doi: 10.1186/s13073-021-01006-6

Functional characterisation of the amyotrophic lateral sclerosis risk locus GPX3/TNIP1

2022

Book Chapter

Biofluid biomarkers of amyotrophic lateral sclerosis

Holdom, Cory J., Steyn, Frederik J., Henderson, Robert D., McCombe, Pamela A., Rogers, Mary-Louise and Ngo, Shyuan T. (2022). Biofluid biomarkers of amyotrophic lateral sclerosis. Neurodegenerative diseases biomarkers: towards translating research to clinical practice. (pp. 263-306) edited by Philip V. Peplow, Bridget Martinez and Thomas A. Gennarelli. New York, United States: Springer . doi: 10.1007/978-1-0716-1712-0_11

Biofluid biomarkers of amyotrophic lateral sclerosis

2021

Journal Article

Common and rare variant association analyses in amyotrophic lateral sclerosis identify 15 risk loci with distinct genetic architectures and neuron-specific biology

van Rheenen, Wouter, van der Spek, Rick A. A., Bakker, Mark K., van Vugt, Joke J. F. A., Hop, Paul J., Zwamborn, Ramona A. J., de Klein, Niek, Westra, Harm-Jan, Bakker, Olivier B., Deelen, Patrick, Shireby, Gemma, Hannon, Eilis, Moisse, Matthieu, Baird, Denis, Restuadi, Restuadi, Dolzhenko, Egor, Dekker, Annelot M., Gawor, Klara, Westeneng, Henk-Jan, Tazelaar, Gijs H. P., van Eijk, Kristel R., Kooyman, Maarten, Byrne, Ross P., Doherty, Mark, Heverin, Mark, Al Khleifat, Ahmad, Iacoangeli, Alfredo, Shatunov, Aleksey, Ticozzi, Nicola ... SLAP Consortium (2021). Common and rare variant association analyses in amyotrophic lateral sclerosis identify 15 risk loci with distinct genetic architectures and neuron-specific biology. Nature Genetics, 53 (12), 1636-1648. doi: 10.1038/s41588-021-00973-1

Common and rare variant association analyses in amyotrophic lateral sclerosis identify 15 risk loci with distinct genetic architectures and neuron-specific biology

2021

Journal Article

Comprehensive cell type decomposition of circulating cell-free DNA with CelFiE

Caggiano, Christa, Celona, Barbara, Garton, Fleur, Mefford, Joel, Black, Brian L., Henderson, Robert, Lomen-Hoerth, Catherine, Dahl, Andrew and Zaitlen, Noah (2021). Comprehensive cell type decomposition of circulating cell-free DNA with CelFiE. Nature Communications, 12 (1) 2717. doi: 10.1038/s41467-021-22901-x

Comprehensive cell type decomposition of circulating cell-free DNA with CelFiE

2021

Journal Article

Venous creatinine as a biomarker for loss of fat‐free mass and disease progression in patients with Amyotrophic Lateral Sclerosis

Holdom, Cory J., Janse van Mantgem, Mark R., van Eijk, Ruben P.A., Howe, Stephanie L., van den Berg, Leonard H., McCombe, Pamela A., Henderson, Robert D., Ngo, Shyuan T. and Steyn, Frederik J. (2021). Venous creatinine as a biomarker for loss of fat‐free mass and disease progression in patients with Amyotrophic Lateral Sclerosis. European Journal of Neurology, 28 (11) ene.15003, 3615-3625. doi: 10.1111/ene.15003

Venous creatinine as a biomarker for loss of fat‐free mass and disease progression in patients with Amyotrophic Lateral Sclerosis

2021

Journal Article

Phase 1b dose-escalation, safety, and pharmacokinetic study of IC14, a monoclonal antibody against CD14, for the treatment of amyotrophic lateral sclerosis

Henderson, Robert D., Agosti, Jan M., McCombe, Pamela A., Thorpe, Kathryn, Heggie, Susan, Heshmat, Saman, Appleby, Mark W., Ziegelaar, Brian W., Crowe, David T. and Redlich, Garry L. (2021). Phase 1b dose-escalation, safety, and pharmacokinetic study of IC14, a monoclonal antibody against CD14, for the treatment of amyotrophic lateral sclerosis. Medicine, 100 (42), e27421. doi: 10.1097/MD.0000000000027421

Phase 1b dose-escalation, safety, and pharmacokinetic study of IC14, a monoclonal antibody against CD14, for the treatment of amyotrophic lateral sclerosis

2021

Journal Article

Assessing the upper motor neurone: novel UMN biomarkers are needed for clinical trials

Henderson, Robert D. and Devine, Matthew S. (2021). Assessing the upper motor neurone: novel UMN biomarkers are needed for clinical trials. Journal of Neurology, Neurosurgery and Psychiatry, 93 (1), 3-3. doi: 10.1136/jnnp-2021-327948

Assessing the upper motor neurone: novel UMN biomarkers are needed for clinical trials

2021

Journal Article

MiNDAUS partnership: a roadmap for the cure and management of motor Neurone disease

Vucic, Steve, Wray, Naomi, Henders, Anjali, Henderson, Robert D., Talman, Paul, Mathers, Susan, Bellgard, Matthew, Aoun, Samar, Birks, Carol, Thomas, Gethin, Hansen, Catherine, Thomas, Geoff, Hogden, Anne, Needham, Merrilee, Schultz, David, Soulis, Tina, Sheean, Bec, Milne, Jane, Rowe, Dominic, Zoing, Margie and Kiernan, Matthew C (2021). MiNDAUS partnership: a roadmap for the cure and management of motor Neurone disease. Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 23 (5-6), 1-8. doi: 10.1080/21678421.2021.1980889

MiNDAUS partnership: a roadmap for the cure and management of motor Neurone disease

Current funding

  • 2024 - 2026
    Predicting functional decline in MND using metabolic body mapping
    Cure for MND Foundation - Impact Grants
    Open grant
  • 2024 - 2025
    AMII: Asia-pacific MND Imaging Initiative (2022 FightMND Collaborative Initiatives Grant administered by The University of Sydney)
    University of Sydney
    Open grant
  • 2023 - 2027
    Save our Speech (SoS) Study: Towards automated speech biomarkers of disease progression and treatment responsiveness in amyotrophic lateral sclerosis (ALS).
    Motor Neurone Disease Research Institute of Australia Inc Innovator Grant
    Open grant

Past funding

  • 2022
    Targeting inflammasome-driven neuropathology and motor neuron death in MND using a clinically approved cancer drug.
    Motor Neurone Disease Research Institute of Australia Inc Linda Rynalski Bridge Funding Grant
    Open grant
  • 2021 - 2022
    Targeting NAT1 to improve metabolism and slow disease progression in MND
    Motor Neurone Disease Research Institute of Australia Inc Innovator Grant
    Open grant
  • 2021 - 2024
    A Novel PET Imaging Market of Astrocytes and Glutamate Reuptake in Brain and Spinal Cord in Amyotrophic Lateral Sclerosis
    Motor Neurone Disease Research Institute of Australia Inc
    Open grant
  • 2021 - 2022
    N-acetyltransferase 1, a modifier of disease outcome in patients with Motor Neurone Disease (MND).
    Metro North Hospital and Health Service
    Open grant
  • 2020 - 2022
    Targeting inflammasome-driven neuropathology and motor neuron death in MND using a clinically approved cancer drug.
    Motor Neurone Disease Research Institute of Australia Inc
    Open grant
  • 2020 - 2021
    Investigating the immunometabolic nature of motor neurone disease (MND): a study linking metabolism, inflammation, and clinical outcomes in MND patients
    Metro North Hospital and Health Service
    Open grant
  • 2020 - 2022
    Development of biomarkers for loss of fat free mass and disease progression in patients with Motor Neurone Disease
    Royal Brisbane and Women's Hospital
    Open grant
  • 2019 - 2020
    Immunogenetics of motor neurone disease - a pilot study
    Motor Neurone Disease Research Institute of Australia Inc
    Open grant
  • 2018 - 2021
    A novel ephrin receptor A4-Fc fusion protein for the treatment of motor neuron disease
    Cure for MND Foundation - Translational Research Grants
    Open grant
  • 2018 - 2019
    Novel biomarkers for motor neurone disease
    Motor Neurone Disease Research Institute of Australia Inc
    Open grant
  • 2018 - 2023
    Motor Neurone Disease: Patient centred care for a progressive neurological disease - evidence driving policy (NHMRC Partnership Project administered by the University of Sydney)
    University of Sydney
    Open grant
  • 2018 - 2019
    Longitudinal assessment of behaviour and cognition in ALS through brief Online Carers' behavioural Questionnaire (OCQ)
    Motor Neurone Disease Research Institute of Australia Inc
    Open grant
  • 2018 - 2019
    Investigating the proteome of MND brains
    Metro North Hospital and Health Service
    Open grant
  • 2018 - 2020
    Use of mass spectrometry to identify circulating toxins in the people with ALS
    Wesley Merdical Research
    Open grant
  • 2018 - 2019
    Use of Point-of-Care (PoC) testing to improve respiratory management and monitor disease progression in ALS: A pilot study
    Metro North Hospital and Health Service
    Open grant
  • 2017 - 2019
    Defining inflammatory biomarkers in motor neuron disease patients to assist in clinical trial efficiency of the C5aR antagonist PMX205
    Wesley Medical Research Ltd
    Open grant
  • 2017
    Discovery of EAAT5 - a protein that may stop glutamate excitotoxicity in ALS
    Motor Neurone Disease Research Institute of Australia Inc
    Open grant
  • 2017 - 2018
    Metabolic exploration in neurodegenerative disease (MEND): synergy between derangements in systemic and muscle metabolism in MND
    Motor Neurone Disease Research Institute of Australia Inc
    Open grant
  • 2016
    Metabolic and gut dynamics in MND: Identifying novel strategies to meet energy needs in patients
    Motor Neurone Disease Research Institute of Australia Inc
    Open grant
  • 2016
    Using biomarkers to explore heterogeneity of motor neurone disease
    Motor Neurone Disease Research Institute of Australia Inc
    Open grant
  • 2015
    A multicentre study of the impact of metabolic balance and dietary intake on the clinical parameters of disease progression
    Motor Neurone Disease Research Institute of Australia Inc
    Open grant
  • 2015
    Blood biomarkers in ALS: Translation into clinical practice of pNfH and search for additional biomarkers using proteomics
    Motor Neurone Disease Research Institute of Australia Inc
    Open grant
  • 2015
    Mass spectrometry to search for biomarkers in motor neurone disease
    Royal Brisbane and Women's Hospital
    Open grant
  • 2015
    The role of altered neuromuscular activity and mRNA transport in modifying the progression of Motor Neuron Disease
    Royal Brisbane and Women's Hospital Foundation
    Open grant
  • 2015
    The role of altered neuronal activity and mRNA transport in modifying the progression Motor Neuron Disease (MND)
    Royal Brisbane and Women's Hospital Foundation
    Open grant
  • 2014
    Targeting EphA4 as a treatment for MND
    Motor Neurone Disease Research Institute of Australia Inc
    Open grant
  • 2014 - 2015
    The role of altered neuromuscular signaling in ALS: factors that modify the course of MND
    Motor Neurone Disease Research Institute of Australia Inc
    Open grant
  • 2014 - 2015
    Whole exome sequencing of sporadic MND
    Motor Neurone Disease Research Institute of Australia Inc
    Open grant
  • 2013 - 2014
    Biomarkers of disease progression in MND
    UQ Academic Title Holder Research Fund
    Open grant
  • 2013
    Use of biomarkers to understand Amyotrophic Lateral Sclerosis
    Motor Neurone Disease Research Institute of Australia Inc
    Open grant
  • 2013
    Using biomarkers to assess disease progression and understanding of MND
    Royal Brisbane and Women's Hospital
    Open grant
  • 2012 - 2013
    Blood Biomarkers in Motor Neurone Disease
    Royal Brisbane and Women's Hospital
    Open grant
  • 2012
    MND - not a simple disease
    Motor Neurone Disease Research Institute of Australia Inc
    Open grant
  • 2011
    Comprehensive assessment of MND patients as a means to studying progression and identifying disease subtypes
    Motor Neurone Disease Research Institute of Australia Inc
    Open grant
  • 2011 - 2013
    Nature and timing of inflammation after acute ischaemic stroke
    National Heart Foundation of Australia
    Open grant
  • 2009 - 2012
    Development of a new method of motor unit number estimation for use in motor neurone disease
    NHMRC Project Grant
    Open grant
  • 2009 - 2010
    Identifying biomarkers for MND using flow cytometry.
    Motor Neurone Disease Research Institute of Australia Inc
    Open grant
  • 2008 - 2011
    Clinical efficacy and physiological mechanisms of nerve and tendon gliding exercises for carpal tunnel syndrome.
    NHMRC Project Grant
    Open grant
  • 2005 - 2006
    Supplementary funding to advance development
    Royal Brisbane & Women's Hospital Research Foundation
    Open grant
  • 2002 - 2004
    Motor Unit Analysis in Motor Neurone Disease
    Motor Neurone Disease Association Queensland Inc
    Open grant

Availability

Associate Professor Robert Henderson is:
Available for supervision

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Supervision history

Current supervision

Completed supervision

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