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Professor Andrew Martin
Professor

Andrew Martin

Email: 

Overview

Background

Andrew Martin is inaugural Professor of Innovative Clinical Trials and leads the University of Queensland’s cLinical Trials cApability (ULTRA) program. Andrew was Professor in the biostatistics group at the NHMRC Clinical Trials Centre University of Sydney. He maintains that role in an honorary capacity since joining UQ. Prior to academia, Andrew held senior biostatistics roles within research-based pharmaceutical organisations (Pfizer and Roche).

orcid ID: 0000-0001-5804-2295

Scopus Author ID: 57223730436

Grants

Category 1: $14.3M Category 3: $131.8M

Grants: 2023 Clinical Trials and Cohort Studies Grant ID 2032441 ($1,362,000): P3BEP Trial - Accelerating First-Line Chemotherapy to Improve Cure Rates for Advanced Germ Cell Tumours; 2022 NHMRC Partnership Projects Grant 2015773 ($1,166,592): Strengthening healthcare systems with Patient Reported Outcome Measures (PROMs); 2020 CA ($600,000): Immuno-metabolic biomarkers for metastatic prostate cancer treatment response; 2018 MRFF Grant APP1170066 ($1,596,631): WHEAT Study on reducing NEC in preterm infants; 2018 CA Grant APP1158397 ($479,375): SCORE trial for shared colorectal cancer care; 2018 CA Grant APP1159837 ($600,000): P3BEP Trial for advanced germ cell tumours; 2018 NHMRC Project Grant APP1159787 ($1,587,163): BCG+MM Trial for bladder cancer; 2016 Victorian Cancer ($300,000): SCORE project on shared care of Colorectal cancer survivors; 2015 CA Priority-driven Collaborative Cancer Research Scheme ($443,307): LEAD - Lung cancer diagnostic and treatment pathways; 2015 NHMRC Project Grant 1108328 ($624,824): Oral Nicotinamide for skin cancer chemoprevention after Transplant; 2014 Co-funded Grant 1079794 ($597,095): Methoxyflurane to reduce discomfort of prostate biopsy; 2013 NHMRC Project Grant 1064121 ($880,425): CHEST Australia project for quicker primary care consultations in lung cancer; 2012 NHMRC Project Grant APP1047100 ($2,203,171): Bovine lactoferrin study on low birthweight infants; 2011 National Breast Cancer Foundation ($199,606): Physical well-being for metastatic breast cancer; 2011 NHMRC Project Grant 1028555 ($187,018): Evidence on reduced child obesity rates; 2011 NHMRC Project Grant 1026977 ($586,691): Oral nicotinamide for skin cancer prevention; 2011 Australasian College of Dermatologists grant ($25,000): Nicotinamide for non-melanoma skin cancer in renal transplant recipients; 2010 NHMRC Project Grant 1007628 ($369,208): NEU-HORIZONS study on riluzole for oxaliplatin neurotoxicity; 2010 NHMRC Project Grant 1003414 ($564,410): Phase II prostate cancer follow-up trial in primary care.

Statistical lead on the following projects receiving industry funding with USyd as administering institution: ENZARAD NCT02446444 ($12,178,000); ENZAMET NCT02446405 ($20,408,129); INTEGRATE ACTRN12612000239864 ($6,900,000); INTEGRATE IIa ACTRN12616000420448 ($22,264,248); INTEGRATE IIb NCT04879368 ($36,330,215); DASL-HiCaP NCT04136353 ($33,777,579).

Availability

Professor Andrew Martin is:
Available for supervision

Research impacts

Research Achievements and Collaborations: Has made original, innovative, and distinguished contributions to methodological research, as well as the design, conduct, analysis, interpretation, and dissemination of clinical research that has had an impact at an international level policy, practice, and subsequent research programs. Has been responsible for the provision of statistical leadership to collaborative trials groups to design, undertake, analyse, and report on clinical trials, as well as promoting investigator-initiated research activities. 2020-2024 Scopus/SciVal author publication metrics: FWCI of 5.21, 51% in top 10% most cited worldwide, 39% international collaboration 3,763 citations (10,934 overall). Received the 2020 ACTA (Australian Clinical Trials Alliance) Statistics in Trials Interest Group Excellence in Trial Statistics Award for ENZAMET Trial. Research funding in last 5 years: $3.1M category 1 and $76.7M category 3.

Contributions to the Field: Led methodological research with international impact. Examples in the last 5 years focus on the topic of changes to the design of ongoing trials. This work has been cited in the CONSERVE 2021 Statement (JAMA. 2021;326(3):257-265 FWCI 7.38; top 1% of general medical journals). Also co-published innovative method for appropriately adjusting estimates of effect obtained from trials that terminate early based on the results of an interim analysis (Statistical Methods in Medical Research – top 11% for statistics journals). Co-designed andled the statistical aspects of design, conduct, analysis, and interpretation of many trial. Two key examples in the last 5 years include ENZAMET and TheraP. (1) ENZAMET study selected for plenary presentation at ASCO (peak international clinical oncology conference attended by over 30,000 international delegates). Am second author for both main N Engl J Med paper (2019;381:121) (journal ranked top 1% general medicine), the quality of life J Clin Oncol paper (2022;40:837-46) (journal ranked top 2% cancer research), and the follow-up Lancet Oncol paper (2022;23:1389) (journal ranked top 1% cancer research). Results were used in support of successful registration of enzalutamide with US FDA in this indication and have been incorporated into US and European treatment guidelines. (2) TheraP evaluated efficacy of cutting-edge targeted radiopharmaceutical (Lu-PSMA) in advance prostate cancer that delivers radiation to cells expressing the prostate-specific membrane antigen. Selected for oral presentation at highly prestigious ASCO 2020 and ASCO GU 2021 conferences. Second senior author of The Lancet paper (2021;397:797) (journal ranked top 1% general medicine). Has led to 2 additional RCTs of Lu-PSMA that I co-designed. One (ENZA-p) was just published in Lancet Oncol (2024 Apr 12:S1470-2045(24)00135-9) (journal ranked top 1% cancer research).

Works

Search Professor Andrew Martin’s works on UQ eSpace

221 works between 1991 and 2025

201 - 220 of 221 works

2012

Journal Article

Effectiveness and cost-effectiveness of sentinel lymph node biopsy compared with axillary node dissection in patients with early-stage breast cancer: A decision model analysis

Verry, H., Lord, S. J., Martin, A., Gill, G., Lee, C. K., Howard, K., Wetzig, N. and Simes, J. (2012). Effectiveness and cost-effectiveness of sentinel lymph node biopsy compared with axillary node dissection in patients with early-stage breast cancer: A decision model analysis. British Journal of Cancer, 106 (6), 1045-1052. doi: 10.1038/bjc.2012.62

Effectiveness and cost-effectiveness of sentinel lymph node biopsy compared with axillary node dissection in patients with early-stage breast cancer: A decision model analysis

2012

Journal Article

Identification of infants with major cognitive delay using parental report

Martin, Andrew J., Darlow, Brian A., Salt, Alison, Hague, Wendy, Sebastian, Lucille, Mann, Kristy and Tarnow-Mordi, William (2012). Identification of infants with major cognitive delay using parental report. Developmental Medicine and Child Neurology, 54 (3), 254-259. doi: 10.1111/j.1469-8749.2011.04161.x

Identification of infants with major cognitive delay using parental report

2012

Journal Article

Oral nicotinamide reduces actinic keratoses in phase II double-blinded randomized controlled trials

Surjana, Devita, Halliday, Gary M., Martin, Andrew J., Moloney, Fergal J. and Damian, Diona L. (2012). Oral nicotinamide reduces actinic keratoses in phase II double-blinded randomized controlled trials. Journal of Investigative Dermatology, 132 (5), 1497-1500. doi: 10.1038/jid.2011.459

Oral nicotinamide reduces actinic keratoses in phase II double-blinded randomized controlled trials

2011

Journal Article

Safety and efficacy of pregabalin in patients with central post-stroke pain

Kim, Jong S., Bashford, Guy, Murphy, T. Kevin, Martin, Andrew, Dror, Vardit and Cheung, Raymond (2011). Safety and efficacy of pregabalin in patients with central post-stroke pain. Pain, 152 (5), 1018-1023. doi: 10.1016/j.pain.2010.12.023

Safety and efficacy of pregabalin in patients with central post-stroke pain

2011

Journal Article

Efficacy of Pregabalin for Peripheral Neuropathic Pain: Results of an 8-Week, Flexible-Dose, Double-Blind, Placebo-Controlled Study Conducted in China

Guan, Yuzhou, Ding, Xinsheng, Cheng, Yan, Fan, Dongsheng, Tan, Lan, Wang, Yongjun, Zhao, Zhongxin, Hong, Zhen, Zhou, Dong, Pan, Xiaoping, Chen, Shengdi, Martin, Andrew, Tang, Haiyun and Cui, Liying (2011). Efficacy of Pregabalin for Peripheral Neuropathic Pain: Results of an 8-Week, Flexible-Dose, Double-Blind, Placebo-Controlled Study Conducted in China. Clinical Therapeutics, 33 (2), 159-166. doi: 10.1016/j.clinthera.2011.02.007

Efficacy of Pregabalin for Peripheral Neuropathic Pain: Results of an 8-Week, Flexible-Dose, Double-Blind, Placebo-Controlled Study Conducted in China

2010

Journal Article

A Verification System for Interval-Based Specification Languages

Chen, Chunqing, Dong, Jin Song, Sun, Jun and Martin, Andrew (2010). A Verification System for Interval-Based Specification Languages. Acm Transactions On Software Engineering and Methodology, 19 (4) 13. doi: 10.1145/1734229.1734232

A Verification System for Interval-Based Specification Languages

2005

Journal Article

Randomized trial of sertraline versus venlafaxine XR in major depression: Efficacy and discontinuation symptoms

Sir, Aytekin, D'Souza, Russell F., Uguz, Sukru, George, Tom, Vahip, Simavi, Hopwood, Malcolm, Martin, Andrew J., Lam, William and Burt, Tal (2005). Randomized trial of sertraline versus venlafaxine XR in major depression: Efficacy and discontinuation symptoms. Journal of Clinical Psychiatry, 66 (10), 1312-1320. doi: 10.4088/JCP.v66n1015

Randomized trial of sertraline versus venlafaxine XR in major depression: Efficacy and discontinuation symptoms

2004

Journal Article

A phase II trial of capecitabine in heavily pre-treated platinum-resistant ovarian cancer

Rischin, Danny, Phillips, Kelly-Anne, Friedlander, Michael, Harnett, Paul, Quinn, Michael, Richardson, Gary and Martin, Andrew (2004). A phase II trial of capecitabine in heavily pre-treated platinum-resistant ovarian cancer. Gynecologic Oncology, 93 (2), 417-421. doi: 10.1016/j.ygyno.2004.01.037

A phase II trial of capecitabine in heavily pre-treated platinum-resistant ovarian cancer

2003

Journal Article

The benefits and costs of tamoxifen for breast cancer prevention

Eckermann, Simon D., Martin, Andrew J., Stockler, Martin R. and Simes, R. John (2003). The benefits and costs of tamoxifen for breast cancer prevention. Australian and New Zealand Journal of Public Health, 27 (1), 34-40. doi: 10.1111/j.1467-842X.2003.tb00377.x

The benefits and costs of tamoxifen for breast cancer prevention

2002

Journal Article

Cholesterol-lowering therapy with pravastatin in patients with average cholesterol levels and established ischaemic heart disease: is it cost-effective?

Glasziou, P. P., Eckermann, S. D., Mulray, S. E., Simes, R. J., Martin, A. J., Kirby, A. C., Hall, J. P., Caleo, S., White, H. D. and Tonkin, A. M. (2002). Cholesterol-lowering therapy with pravastatin in patients with average cholesterol levels and established ischaemic heart disease: is it cost-effective?. Medical Journal of Australia, 177 (8), 428-434. doi: 10.5694/j.1326-5377.2002.tb04883.x

Cholesterol-lowering therapy with pravastatin in patients with average cholesterol levels and established ischaemic heart disease: is it cost-effective?

2000

Journal Article

A comparison of standard gamble, time trade-off and adjusted time trade-off scores

Martin, A., Glasziou, P. P., Simes, R. J. and Lumley, T. (2000). A comparison of standard gamble, time trade-off and adjusted time trade-off scores. International Journal of Technology Assessment in Health, 16 (1), 137-147. doi: 10.1017/S0266462300161124

A comparison of standard gamble, time trade-off and adjusted time trade-off scores

2000

Journal Article

Successful treatment of invasive nasal cryptococcosis in a ferret

Malik, R., Martin, P., McGill, J., Martin, A. and Love, D. N. (2000). Successful treatment of invasive nasal cryptococcosis in a ferret. Australian Veterinary Journal, 78 (3), 158-159. doi: 10.1111/j.1751-0813.2000.tb10582.x

Successful treatment of invasive nasal cryptococcosis in a ferret

1999

Journal Article

Quality of life assessment, evidence-based medicine and cancer prevention

Martin, A. (1999). Quality of life assessment, evidence-based medicine and cancer prevention. Cancer Forum, 23 (3), 142-143.

Quality of life assessment, evidence-based medicine and cancer prevention

1999

Journal Article

A cardiovascular extension of the Health Measurement Questionnaire

Martin, A. J., Glasziou, P. P. and Simes, R. J. (1999). A cardiovascular extension of the Health Measurement Questionnaire. Journal of Epidemiology and Community Health, 53 (9), 548-557. doi: 10.1136/jech.53.9.548

A cardiovascular extension of the Health Measurement Questionnaire

1998

Journal Article

Predicting patients' utilities from quality of life items: an improved scoring system for the UBQ-H

Martin, A. J., Glasziou, P. P., Simes, R. J. and Lumley, T. (1998). Predicting patients' utilities from quality of life items: an improved scoring system for the UBQ-H. Quality of Life Research, 7 (8), 703-711. doi: 10.1023/A:1008857131564

Predicting patients' utilities from quality of life items: an improved scoring system for the UBQ-H

1998

Journal Article

Prevention of cardiovascular events and death with pravastatin in patients with coronary heart disease and a broad range of initial cholesterol levels

Tonkin, A., Aylward, P., Colquhoun, D., Glasziou, P., Harris, P., MacMahon, S., Magnus, P., Newel, D., Nestel, P., Sharpe, N., Hunt, D., Shaw, J., Simes, R. J., Thompson, P., Thomson, A., West, M., White, H., Simes, S., Hague, W., Caleo, S., Hall, J., Martin, A., Mulray, S., Barter, P., Beilin, L., Collins, R., McNeil, J., Meier, P., Willimott, H. ... Keech, A. (1998). Prevention of cardiovascular events and death with pravastatin in patients with coronary heart disease and a broad range of initial cholesterol levels. New England Journal of Medicine, 339 (19), 1349-1357. doi: 10.1056/NEJM199811053391902

Prevention of cardiovascular events and death with pravastatin in patients with coronary heart disease and a broad range of initial cholesterol levels

1998

Journal Article

Quality-of-life assessment in health care research and practice

Martin, Andrew J. and Stockler, Martin (1998). Quality-of-life assessment in health care research and practice. Evaluation and the Health Professions, 21 (2), 141-156. doi: 10.1177/016327879802100202

Quality-of-life assessment in health care research and practice

1995

Journal Article

Design features and baseline characteristics of the LIPID (long-term intervention with pravastatin in ischemic disease) study: A randomized trial in patients with previous acute myocardial infarction and/or unstable angina pectoris

Tonkin, A., Aylward, P., Colquhoun, D., Glasziou, P., Harris, P., Hunt, D., MacMahon, S., Nestel, P., Sharpe, N., Símes, J., Thompson, P., Thomson, A., West, M., White, H., Shaw, J., Ablett, M., MacAskill, M., Turner, R., Magnus, P., Wallace, P., Keech, A., Newell, D., Raupach, H., Hague, W., Hall, J., Mulray, S., Wiseman, V., Davies, P., Smithers, D. ... Thompson, R. (1995). Design features and baseline characteristics of the LIPID (long-term intervention with pravastatin in ischemic disease) study: A randomized trial in patients with previous acute myocardial infarction and/or unstable angina pectoris. The American Journal of Cardiology, 76 (7), 474-479. doi: 10.1016/S0002-9149(99)80133-7

Design features and baseline characteristics of the LIPID (long-term intervention with pravastatin in ischemic disease) study: A randomized trial in patients with previous acute myocardial infarction and/or unstable angina pectoris

1995

Journal Article

A controlled trial of a behavioral and educational intervention following coronary artery bypass surgery

Oldenburg, B., Martin, A., Greenwood, J., Bernstein, L. and Allan, R. (1995). A controlled trial of a behavioral and educational intervention following coronary artery bypass surgery. Journal of Cardiopulmonary Rehabilitation, 15 (1), 39-46. doi: 10.1097/00008483-199501000-00006

A controlled trial of a behavioral and educational intervention following coronary artery bypass surgery

1994

Journal Article

Mark‐recapture estimates of injecting drug users in Sydney

Duque‐Portugal, Francisco, Martin, Andrew J., Taylor, Richard and Ross, Michael W. (1994). Mark‐recapture estimates of injecting drug users in Sydney. Australian Journal of Public Health, 18 (2), 201-204. doi: 10.1111/j.1753-6405.1994.tb00226.x

Mark‐recapture estimates of injecting drug users in Sydney

Funding

Current funding

  • 2024 - 2025
    SAFTEP: Semiparametric Accelerated Failure Time Evaluation Project
    Seed Funding for Methodology Research Scheme
    Open grant
  • 2024 - 2026
    Reducing blood culture contamination with the use of a needle-less blood draw device (PIVO Pro): An adaptive group sequential randomized controlled trial (The PIVO Trial)
    Becton, Dickinson and Company
    Open grant

Supervision

Availability

Professor Andrew Martin is:
Available for supervision

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Supervision history

Current supervision

Media

Enquiries

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