
Overview
Background
Andrew Martin is inaugural Professor of Innovative Clinical Trials and leads the University of Queensland’s cLinical Trials cApability (ULTRA) program. Andrew was Professor in the biostatistics group at the NHMRC Clinical Trials Centre University of Sydney. He maintains that role in an honorary capacity since joining UQ. Prior to academia, Andrew held senior biostatistics roles within research-based pharmaceutical organisations (Pfizer and Roche).
Grants
Category 1: $14.3M Category 3: $131.8M
Grants: 2023 Clinical Trials and Cohort Studies Grant ID 2032441 ($1,362,000): P3BEP Trial - Accelerating First-Line Chemotherapy to Improve Cure Rates for Advanced Germ Cell Tumours; 2022 NHMRC Partnership Projects Grant 2015773 ($1,166,592): Strengthening healthcare systems with Patient Reported Outcome Measures (PROMs); 2020 CA ($600,000): Immuno-metabolic biomarkers for metastatic prostate cancer treatment response; 2018 MRFF Grant APP1170066 ($1,596,631): WHEAT Study on reducing NEC in preterm infants; 2018 CA Grant APP1158397 ($479,375): SCORE trial for shared colorectal cancer care; 2018 CA Grant APP1159837 ($600,000): P3BEP Trial for advanced germ cell tumours; 2018 NHMRC Project Grant APP1159787 ($1,587,163): BCG+MM Trial for bladder cancer; 2016 Victorian Cancer ($300,000): SCORE project on shared care of Colorectal cancer survivors; 2015 CA Priority-driven Collaborative Cancer Research Scheme ($443,307): LEAD - Lung cancer diagnostic and treatment pathways; 2015 NHMRC Project Grant 1108328 ($624,824): Oral Nicotinamide for skin cancer chemoprevention after Transplant; 2014 Co-funded Grant 1079794 ($597,095): Methoxyflurane to reduce discomfort of prostate biopsy; 2013 NHMRC Project Grant 1064121 ($880,425): CHEST Australia project for quicker primary care consultations in lung cancer; 2012 NHMRC Project Grant APP1047100 ($2,203,171): Bovine lactoferrin study on low birthweight infants; 2011 National Breast Cancer Foundation ($199,606): Physical well-being for metastatic breast cancer; 2011 NHMRC Project Grant 1028555 ($187,018): Evidence on reduced child obesity rates; 2011 NHMRC Project Grant 1026977 ($586,691): Oral nicotinamide for skin cancer prevention; 2011 Australasian College of Dermatologists grant ($25,000): Nicotinamide for non-melanoma skin cancer in renal transplant recipients; 2010 NHMRC Project Grant 1007628 ($369,208): NEU-HORIZONS study on riluzole for oxaliplatin neurotoxicity; 2010 NHMRC Project Grant 1003414 ($564,410): Phase II prostate cancer follow-up trial in primary care.
Statistical lead on the following projects receiving industry funding with USyd as administering institution: ENZARAD NCT02446444 ($12,178,000); ENZAMET NCT02446405 ($20,408,129); INTEGRATE ACTRN12612000239864 ($6,900,000); INTEGRATE IIa ACTRN12616000420448 ($22,264,248); INTEGRATE IIb NCT04879368 ($36,330,215); DASL-HiCaP NCT04136353 ($33,777,579).
Availability
- Professor Andrew Martin is:
- Available for supervision
Research impacts
Research Achievements and Collaborations: Has made original, innovative, and distinguished contributions to methodological research, as well as the design, conduct, analysis, interpretation, and dissemination of clinical research that has had an impact at an international level policy, practice, and subsequent research programs. Has been responsible for the provision of statistical leadership to collaborative trials groups to design, undertake, analyse, and report on clinical trials, as well as promoting investigator-initiated research activities. 2020-2024 Scopus/SciVal author publication metrics: FWCI of 5.21, 51% in top 10% most cited worldwide, 39% international collaboration 3,763 citations (10,934 overall). Received the 2020 ACTA (Australian Clinical Trials Alliance) Statistics in Trials Interest Group Excellence in Trial Statistics Award for ENZAMET Trial. Research funding in last 5 years: $3.1M category 1 and $76.7M category 3.
Contributions to the Field: Led methodological research with international impact. Examples in the last 5 years focus on the topic of changes to the design of ongoing trials. This work has been cited in the CONSERVE 2021 Statement (JAMA. 2021;326(3):257-265 FWCI 7.38; top 1% of general medical journals). Also co-published innovative method for appropriately adjusting estimates of effect obtained from trials that terminate early based on the results of an interim analysis (Statistical Methods in Medical Research – top 11% for statistics journals). Co-designed andled the statistical aspects of design, conduct, analysis, and interpretation of many trial. Two key examples in the last 5 years include ENZAMET and TheraP. (1) ENZAMET study selected for plenary presentation at ASCO (peak international clinical oncology conference attended by over 30,000 international delegates). Am second author for both main N Engl J Med paper (2019;381:121) (journal ranked top 1% general medicine), the quality of life J Clin Oncol paper (2022;40:837-46) (journal ranked top 2% cancer research), and the follow-up Lancet Oncol paper (2022;23:1389) (journal ranked top 1% cancer research). Results were used in support of successful registration of enzalutamide with US FDA in this indication and have been incorporated into US and European treatment guidelines. (2) TheraP evaluated efficacy of cutting-edge targeted radiopharmaceutical (Lu-PSMA) in advance prostate cancer that delivers radiation to cells expressing the prostate-specific membrane antigen. Selected for oral presentation at highly prestigious ASCO 2020 and ASCO GU 2021 conferences. Second senior author of The Lancet paper (2021;397:797) (journal ranked top 1% general medicine). Has led to 2 additional RCTs of Lu-PSMA that I co-designed. One (ENZA-p) was just published in Lancet Oncol (2024 Apr 12:S1470-2045(24)00135-9) (journal ranked top 1% cancer research).
Works
Search Professor Andrew Martin’s works on UQ eSpace
2016
Journal Article
Regorafenib for the treatment of advanced gastric cancer (INTEGRATE): A multinational placebo-controlled phase II Trial
Pavlakis, Nick, Sjoquist, Katrin M., Martin, Andrew J., Tsobanis, Eric, Yip, Sonia, Kang, Yoon-Koo, Bang, Yung-Jue, Alcindor, Thierry, O'Callaghan, Christopher J., Burnell, Margot J., Tebbutt, Niall C., Rha, Sun Young, Lee, Jeeyun, Cho, Jae-Yong, Lipton, Lara R., Wong, Mark, Strickland, Andrew, Kim, Jin Won, Zalcberg, John R., Simes, John and Goldstein, David (2016). Regorafenib for the treatment of advanced gastric cancer (INTEGRATE): A multinational placebo-controlled phase II Trial. Journal of Clinical Oncology, 34 (23), 2728-2735. doi: 10.1200/JCO.2015.65.1901
2016
Journal Article
Delivery mode and pelvic organ prolapse: a retrospective observational study
Trutnovsky, G., Kamisan Atan, I., Martin, A. and Dietz, H. P. (2016). Delivery mode and pelvic organ prolapse: a retrospective observational study. BJOG: An International Journal of Obstetrics and Gynaecology, 123 (9), 1551-1556. doi: 10.1111/1471-0528.13692
2016
Conference Publication
Are Multiple Interventions Needed To Influence Physician Prescribing Behaviour: Implications For The Future?
Truter, Ilse, Godman, Brian, Baker, Amanj, Bucsics, Anna, Fadare, Joseph, Hesse, Ulrik, Martin, Andrew, Kwon, Hye Young, Zara, Corinne and Bennie, Marion (2016). Are Multiple Interventions Needed To Influence Physician Prescribing Behaviour: Implications For The Future?. HOBOKEN: WILEY-BLACKWELL.
2016
Journal Article
International prescribing practices in obsessive–compulsive disorder (OCD)
Brakoulias, Vlasios, Starcevic, Vladan, Belloch, Amparo, Dell’Osso, Liliana, Fer rão, Ygor A., Fontenelle, Leonardo F., Lochner, Christine, Marazziti, Donatella, Martin, Andrew, Matsunaga, Hisato, Miguel, Euripedes C., Reddy, Y. C. Janardhan, do Rosário, Maria C., Shavitt, Roseli G., Sundar, Arumugham Shyam, Stein, Dan Joseph and Viswasam, Kirupamani (2016). International prescribing practices in obsessive–compulsive disorder (OCD). Human Psychopharmacology, 31 (4), 319-324. doi: 10.1002/hup.2541
2016
Conference Publication
A PROSPECTIVE, LONGITUDINAL COHORT STUDY TO INVESTIGATE THE IMPACT OF CHEMOTHERAPY ON COGNITION IN TESTICULAR CANCER
Stockler, Martin, Whitford, Hayley S., Kalinowski, Pawel, Schembri, Adrian, Toner, Guy, Grimison, Peter, Martin, Andrew, Davis, Ian, Wong, Nicole and Olver, Ian (2016). A PROSPECTIVE, LONGITUDINAL COHORT STUDY TO INVESTIGATE THE IMPACT OF CHEMOTHERAPY ON COGNITION IN TESTICULAR CANCER. HOBOKEN: WILEY-BLACKWELL.
2016
Conference Publication
LONG-TERM OUTCOMES OF ACCELERATED BEP (BLEOMYCIN, ETOPOSIDE, CISPLATIN) FOR ADVANCED GERM-CELL TUMORS: UPDATED ANALYSIS OF AN AUSTRALIAN MULTICENTER PHASE II TRIAL
Lawrence, Nicola, Martin, Andrew, Toner, Guy, Stockler, Martin, Buizen, Luke, Thomson, Damien, Gebski, Val, Friedlander, Michael, Yeung, Annie, Gurney, Howard, Rosenthal, Mark, Singhal, Nimit, Kichenadasse, Ganessan, Wong, Shirley, Lewis, Craig, Vasey, Paul and Grimison, Peter (2016). LONG-TERM OUTCOMES OF ACCELERATED BEP (BLEOMYCIN, ETOPOSIDE, CISPLATIN) FOR ADVANCED GERM-CELL TUMORS: UPDATED ANALYSIS OF AN AUSTRALIAN MULTICENTER PHASE II TRIAL. HOBOKEN: WILEY-BLACKWELL.
2016
Journal Article
Experimental investigation of a novel solar thermal polygeneration plant in United Arab Emirates
Mohan, Gowtham, Kumar, N. T. Uday, Pokhrel, Manoj Kumar and Martin, Andrew (2016). Experimental investigation of a novel solar thermal polygeneration plant in United Arab Emirates. Renewable Energy, 91, 361-373. doi: 10.1016/j.renene.2016.01.072
2016
Journal Article
Upgrading of a traditional sugar cane mill to a modern mill and assessing the potential of energy saving during steady state and transient conditions-part II: models for a modified cogeneration unit
Birru, Eyerusalem, Erlich, Catharina, Beyene, Getachew Bekele and Martin, Andrew (2016). Upgrading of a traditional sugar cane mill to a modern mill and assessing the potential of energy saving during steady state and transient conditions-part II: models for a modified cogeneration unit. Biomass Conversion and Biorefinery, 6 (2), 233-245. doi: 10.1007/s13399-015-0180-8
2016
Journal Article
What is normal bladder neck anatomy?
Naranjo-Ortiz, Cristina, Shek, Ka Lai, Martin, Andrew James and Dietz, Hans Peter (2016). What is normal bladder neck anatomy?. International Urogynecology Journal, 27 (6), 945-950. doi: 10.1007/s00192-015-2916-1
2016
Journal Article
Assessing the potential of energy saving in a traditional sugar cane mill during steady state and transient conditions-part I: base case plant model
Birru, Eyerusalem, Erlich, Catharina, Beyene, Getachew Bekele and Martin, Andrew (2016). Assessing the potential of energy saving in a traditional sugar cane mill during steady state and transient conditions-part I: base case plant model. Biomass Conversion and Biorefinery, 6 (2), 219-232. doi: 10.1007/s13399-015-0179-1
2016
Journal Article
The familiality of specific symptoms of obsessive-compulsive disorder
Brakoulias, Vlasios, Starcevic, Vladan, Martin, Andrew, Berle, David, Milicevic, Denise and Viswasam, Kirupamani (2016). The familiality of specific symptoms of obsessive-compulsive disorder. Psychiatry Research, 239, 315-319. doi: 10.1016/j.psychres.2016.03.047
2016
Journal Article
Performance analysis of solar cogeneration system with different integration strategies for potable water and domestic hot water production
Kumar, N. T. Uday, Mohan, Gowtham and Martin, Andrew (2016). Performance analysis of solar cogeneration system with different integration strategies for potable water and domestic hot water production. Applied Energy, 170, 466-475. doi: 10.1016/j.apenergy.2016.02.033
2016
Journal Article
Benefit of treatment of latent tuberculosis infection in individual patients
Dobler, Claudia C., Martin, Andrew and Marks, Guy B. (2016). Benefit of treatment of latent tuberculosis infection in individual patients. The European respiratory journal, 47 (5), 1594-1595. doi: 10.1183/13993003.00175-2016
2016
Journal Article
A novel solar thermal polygeneration system for sustainable production of cooling, clean water and domestic hot water in United Arab Emirates: Dynamic simulation and economic evaluation
Mohan, Gowtham, Kumar, Uday, Pokhrel, Manoj Kumar and Martin, Andrew (2016). A novel solar thermal polygeneration system for sustainable production of cooling, clean water and domestic hot water in United Arab Emirates: Dynamic simulation and economic evaluation. Applied Energy, 167, 173-188. doi: 10.1016/j.apenergy.2015.10.116
2016
Journal Article
Perioperative management of diabetes in elective patients: A region-wide audit
Jackson, M. J., Patvardhan, C., Wallace, F., Martin, A., Yusuff, H., Briggs, G. and Malik, R. A. (2016). Perioperative management of diabetes in elective patients: A region-wide audit. British Journal of Anaesthesia, 116 (4), 501-506. doi: 10.1093/bja/aev554
2016
Conference Publication
Permanently grafted abrasion resistant nanocomposites for anti-icing applications
Gao, Jing, Martin, Andrew, Yatvin, Jeremy and Locklin, Jason (2016). Permanently grafted abrasion resistant nanocomposites for anti-icing applications. WASHINGTON: AMER CHEMICAL SOC.
2016
Journal Article
The authors reply
Chen, Andrew C., Martin, Andrew J. and Damian, Diona L. (2016). The authors reply. New England Journal of Medicine, 374 (8). doi: 10.1056/NEJMc1514791
2016
Journal Article
Testing the Assessment of New Radiation Oncology Technology and Treatments framework using the evaluation of post-prostatectomy radiotherapy techniques
Duchesne, Gillian M., Haworth, Annette, Bone, Eric, Carter, Hannah, Ebert, Martin A., Gagliardi, Frank, Gibbs, Adrian, Hornby, Colin, Martin, Andrew, Sidhom, Mark, Wood, Maree and Jackson, Michael (2016). Testing the Assessment of New Radiation Oncology Technology and Treatments framework using the evaluation of post-prostatectomy radiotherapy techniques. Journal of Medical Imaging and Radiation Oncology, 60 (1), 129-137. doi: 10.1111/1754-9485.12390
2016
Journal Article
Relationships between p53 mutation, HPV status and outcome in oropharyngeal squamous cell carcinoma
Hong, Angela, Zhang, Xiaoying, Jones, Deanna, Veillard, Anne-Sophie, Zhang, Mei, Martin, Andrew, Lyons, J. Guy, Lee, C. Soon and Rose, Barbara (2016). Relationships between p53 mutation, HPV status and outcome in oropharyngeal squamous cell carcinoma. Radiotherapy and Oncology, 118 (2), 342-349. doi: 10.1016/j.radonc.2016.02.009
2016
Journal Article
Maternal abdominal subcutaneous fat thickness as a predictor for adverse pregnancy outcome: A longitudinal cohort study
Kennedy, N. J., Peek, M. J., Quinton, A. E., Lanzarone, V., Martin, A., Benzie, R. and Nanan, R. (2016). Maternal abdominal subcutaneous fat thickness as a predictor for adverse pregnancy outcome: A longitudinal cohort study. BJOG: An International Journal of Obstetrics and Gynaecology, 123 (2), 225-232. doi: 10.1111/1471-0528.13758
Funding
Current funding
Supervision
Availability
- Professor Andrew Martin is:
- Available for supervision
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Supervision history
Current supervision
-
Doctor Philosophy
Advanced methods for biomarker informed endometrial cancer
Associate Advisor
Other advisors: Dr Eva Baxter, Dr Zoe West, Professor Andreas Obermair
Media
Enquiries
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