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Professor Andrew Martin
Professor

Andrew Martin

Email: 

Overview

Background

Andrew Martin is inaugural Professor of Innovative Clinical Trials and leads the University of Queensland’s cLinical Trials cApability (ULTRA) program. Andrew was Professor in the biostatistics group at the NHMRC Clinical Trials Centre University of Sydney. He maintains that role in an honorary capacity since joining UQ. Prior to academia, Andrew held senior biostatistics roles within research-based pharmaceutical organisations (Pfizer and Roche).

orcid ID: 0000-0001-5804-2295

Scopus Author ID: 57223730436

Grants

Category 1: $14.3M Category 3: $131.8M

Grants: 2023 Clinical Trials and Cohort Studies Grant ID 2032441 ($1,362,000): P3BEP Trial - Accelerating First-Line Chemotherapy to Improve Cure Rates for Advanced Germ Cell Tumours; 2022 NHMRC Partnership Projects Grant 2015773 ($1,166,592): Strengthening healthcare systems with Patient Reported Outcome Measures (PROMs); 2020 CA ($600,000): Immuno-metabolic biomarkers for metastatic prostate cancer treatment response; 2018 MRFF Grant APP1170066 ($1,596,631): WHEAT Study on reducing NEC in preterm infants; 2018 CA Grant APP1158397 ($479,375): SCORE trial for shared colorectal cancer care; 2018 CA Grant APP1159837 ($600,000): P3BEP Trial for advanced germ cell tumours; 2018 NHMRC Project Grant APP1159787 ($1,587,163): BCG+MM Trial for bladder cancer; 2016 Victorian Cancer ($300,000): SCORE project on shared care of Colorectal cancer survivors; 2015 CA Priority-driven Collaborative Cancer Research Scheme ($443,307): LEAD - Lung cancer diagnostic and treatment pathways; 2015 NHMRC Project Grant 1108328 ($624,824): Oral Nicotinamide for skin cancer chemoprevention after Transplant; 2014 Co-funded Grant 1079794 ($597,095): Methoxyflurane to reduce discomfort of prostate biopsy; 2013 NHMRC Project Grant 1064121 ($880,425): CHEST Australia project for quicker primary care consultations in lung cancer; 2012 NHMRC Project Grant APP1047100 ($2,203,171): Bovine lactoferrin study on low birthweight infants; 2011 National Breast Cancer Foundation ($199,606): Physical well-being for metastatic breast cancer; 2011 NHMRC Project Grant 1028555 ($187,018): Evidence on reduced child obesity rates; 2011 NHMRC Project Grant 1026977 ($586,691): Oral nicotinamide for skin cancer prevention; 2011 Australasian College of Dermatologists grant ($25,000): Nicotinamide for non-melanoma skin cancer in renal transplant recipients; 2010 NHMRC Project Grant 1007628 ($369,208): NEU-HORIZONS study on riluzole for oxaliplatin neurotoxicity; 2010 NHMRC Project Grant 1003414 ($564,410): Phase II prostate cancer follow-up trial in primary care.

Statistical lead on the following projects receiving industry funding with USyd as administering institution: ENZARAD NCT02446444 ($12,178,000); ENZAMET NCT02446405 ($20,408,129); INTEGRATE ACTRN12612000239864 ($6,900,000); INTEGRATE IIa ACTRN12616000420448 ($22,264,248); INTEGRATE IIb NCT04879368 ($36,330,215); DASL-HiCaP NCT04136353 ($33,777,579).

Availability

Professor Andrew Martin is:
Available for supervision

Research impacts

Research Achievements and Collaborations: Has made original, innovative, and distinguished contributions to methodological research, as well as the design, conduct, analysis, interpretation, and dissemination of clinical research that has had an impact at an international level policy, practice, and subsequent research programs. Has been responsible for the provision of statistical leadership to collaborative trials groups to design, undertake, analyse, and report on clinical trials, as well as promoting investigator-initiated research activities. 2020-2024 Scopus/SciVal author publication metrics: FWCI of 5.21, 51% in top 10% most cited worldwide, 39% international collaboration 3,763 citations (10,934 overall). Received the 2020 ACTA (Australian Clinical Trials Alliance) Statistics in Trials Interest Group Excellence in Trial Statistics Award for ENZAMET Trial. Research funding in last 5 years: $3.1M category 1 and $76.7M category 3.

Contributions to the Field: Led methodological research with international impact. Examples in the last 5 years focus on the topic of changes to the design of ongoing trials. This work has been cited in the CONSERVE 2021 Statement (JAMA. 2021;326(3):257-265 FWCI 7.38; top 1% of general medical journals). Also co-published innovative method for appropriately adjusting estimates of effect obtained from trials that terminate early based on the results of an interim analysis (Statistical Methods in Medical Research – top 11% for statistics journals). Co-designed andled the statistical aspects of design, conduct, analysis, and interpretation of many trial. Two key examples in the last 5 years include ENZAMET and TheraP. (1) ENZAMET study selected for plenary presentation at ASCO (peak international clinical oncology conference attended by over 30,000 international delegates). Am second author for both main N Engl J Med paper (2019;381:121) (journal ranked top 1% general medicine), the quality of life J Clin Oncol paper (2022;40:837-46) (journal ranked top 2% cancer research), and the follow-up Lancet Oncol paper (2022;23:1389) (journal ranked top 1% cancer research). Results were used in support of successful registration of enzalutamide with US FDA in this indication and have been incorporated into US and European treatment guidelines. (2) TheraP evaluated efficacy of cutting-edge targeted radiopharmaceutical (Lu-PSMA) in advance prostate cancer that delivers radiation to cells expressing the prostate-specific membrane antigen. Selected for oral presentation at highly prestigious ASCO 2020 and ASCO GU 2021 conferences. Second senior author of The Lancet paper (2021;397:797) (journal ranked top 1% general medicine). Has led to 2 additional RCTs of Lu-PSMA that I co-designed. One (ENZA-p) was just published in Lancet Oncol (2024 Apr 12:S1470-2045(24)00135-9) (journal ranked top 1% cancer research).

Works

Search Professor Andrew Martin’s works on UQ eSpace

221 works between 1991 and 2025

121 - 140 of 221 works

2017

Journal Article

Discussing and prescribing expensive unfunded anticancer drugs in Australia

Karikios, Deme John, Mileshkin, Linda, Martin, Andrew, Ferraro, Danielle and Stockler, Martin R. (2017). Discussing and prescribing expensive unfunded anticancer drugs in Australia. ESMO Open, 2 (2) e000170. doi: 10.1136/esmoopen-2017-000170

Discussing and prescribing expensive unfunded anticancer drugs in Australia

2017

Journal Article

BCG + Mitomycin trial for high-risk non-muscle-invasive bladder cancer: progress report and lessons learned

Hayne, Dickon, Stockler, Martin, McCombie, Steve P., Lawrence, Nicola, Martin, Andrew, Sengupta, Shomik and Davis, Ian D. (2017). BCG + Mitomycin trial for high-risk non-muscle-invasive bladder cancer: progress report and lessons learned. BJU International, 119 (S5), 55-57. doi: 10.1111/bju.13873

BCG + Mitomycin trial for high-risk non-muscle-invasive bladder cancer: progress report and lessons learned

2017

Journal Article

Is it all about price? Why requests for government subsidy of anticancer drugs were rejected in Australia

Karikios, Deme J., Chim, Lesley, Martin, Andrew, Nagrial, Adnan, Howard, Kirsten, Salkeld, Glenn and Stockler, Martin R. (2017). Is it all about price? Why requests for government subsidy of anticancer drugs were rejected in Australia. Internal Medicine Journal, 47 (4), 400-407. doi: 10.1111/imj.13350

Is it all about price? Why requests for government subsidy of anticancer drugs were rejected in Australia

2017

Journal Article

Intrapartum predictors of maternal levator ani injury

Caudwell-Hall, Jessica, Kamisan Atan, Ixora, Martin, Andrew, Guzman Rojas, Rodrigo, Langer, Susanne, Shek, Kalai and Dietz, Hans P. (2017). Intrapartum predictors of maternal levator ani injury. Acta Obstetricia et Gynecologica Scandinavica, 96 (4), 426-431. doi: 10.1111/aogs.13103

Intrapartum predictors of maternal levator ani injury

2017

Journal Article

ProCare Trial: a phase II randomized controlled trial of shared care for follow-up of men with prostate cancer

Emery, Jon D., Jefford, Michael, King, Madeleine, Hayne, Dickon, Martin, Andrew, Doorey, Juanita, Hyatt, Amelia, Habgood, Emily, Lim, Tee, Hawks, Cynthia, Pirotta, Marie, Trevena, Lyndal and Schofield, Penelope (2017). ProCare Trial: a phase II randomized controlled trial of shared care for follow-up of men with prostate cancer. BJU International, 119 (3), 381-389. doi: 10.1111/bju.13593

ProCare Trial: a phase II randomized controlled trial of shared care for follow-up of men with prostate cancer

2017

Journal Article

Exergy Analysis of Air-Gap Membrane Distillation Systems for Water Purification Applications

Woldemariam, Daniel, Martin, Andrew and Santarelli, Massimo (2017). Exergy Analysis of Air-Gap Membrane Distillation Systems for Water Purification Applications. Applied Sciences-Basel, 7 (3) 301, 301. doi: 10.3390/app7030301

Exergy Analysis of Air-Gap Membrane Distillation Systems for Water Purification Applications

2017

Journal Article

Parallel multicentre randomised trial of a clinical trial question prompt list in patients considering participation in phase 3 cancer treatment trials

Tattersall, Martin H N, Jefford, Michael, Martin, Andrew, Olver, Ian, Thompson, John F, Brown, Richard F and Butow, Phyllis N (2017). Parallel multicentre randomised trial of a clinical trial question prompt list in patients considering participation in phase 3 cancer treatment trials. BMJ Open, 7 (3) e012666. doi: 10.1136/bmjopen-2016-012666

Parallel multicentre randomised trial of a clinical trial question prompt list in patients considering participation in phase 3 cancer treatment trials

2017

Journal Article

Thermodynamic and economy analysis of solid oxide electrolyser system for syngas production

Samavati, Mahrokh, Santarelli, Massimo, Martin, Andrew and Nemanova, Vera (2017). Thermodynamic and economy analysis of solid oxide electrolyser system for syngas production. Energy, 122, 37-49. doi: 10.1016/j.energy.2017.01.067

Thermodynamic and economy analysis of solid oxide electrolyser system for syngas production

2017

Journal Article

The effect of anti-angiogenic agents on overall survival in metastatic oesophago-gastric cancer: A systematic review and meta-analysis

Chan, David L., Sjoquist, Katrin M., Goldstein, David, Price, Timothy J., Martin, Andrew J., Bang, Yung-Jue, Kang, Yoon-Koo and Pavlakis, Nick (2017). The effect of anti-angiogenic agents on overall survival in metastatic oesophago-gastric cancer: A systematic review and meta-analysis. PLoS ONE, 12 (2) e0172307, e0172307. doi: 10.1371/journal.pone.0172307

The effect of anti-angiogenic agents on overall survival in metastatic oesophago-gastric cancer: A systematic review and meta-analysis

2017

Journal Article

Authors' response to a reply to ‘A phase II randomized controlled trial of nicotinamide for skin cancer chemoprevention in renal transplant recipients’

Damian, D. L., Martin, A. J., Scolyer, R. A., Chen, A. C. and Halliday, G. M. (2017). Authors' response to a reply to ‘A phase II randomized controlled trial of nicotinamide for skin cancer chemoprevention in renal transplant recipients’. British Journal of Dermatology, 176 (2), 552-553. doi: 10.1111/bjd.15204

Authors' response to a reply to ‘A phase II randomized controlled trial of nicotinamide for skin cancer chemoprevention in renal transplant recipients’

2017

Journal Article

Exergy analysis of a polygeneration-enabled district heating and cooling system based on gasification of refuse derived fuel

Kabalina, Natalia, Costa, Mario, Yang, Weihong, Martin, Andrew and Santarelli, Massimo (2017). Exergy analysis of a polygeneration-enabled district heating and cooling system based on gasification of refuse derived fuel. Journal of Cleaner Production, 141, 760-773. doi: 10.1016/j.jclepro.2016.09.151

Exergy analysis of a polygeneration-enabled district heating and cooling system based on gasification of refuse derived fuel

2017

Journal Article

Fampridine treatment and walking distance in multiple sclerosis: A randomised controlled trial

Pickering, Hannah, Murray, Jenna, Lin, Cindy S.-Y., Cormack, Christine, Martin, Andrew, Kiernan, Matthew C. and Krishnan, Arun V. (2017). Fampridine treatment and walking distance in multiple sclerosis: A randomised controlled trial. Clinical Neurophysiology, 128 (1), 93-99. doi: 10.1016/j.clinph.2016.10.088

Fampridine treatment and walking distance in multiple sclerosis: A randomised controlled trial

2016

Journal Article

Membrane distillation pilot plant trials with pharmaceutical residues and energy demand analysis

Woldemariam, Daniel, Kullab, Alaa, Fortkamp, Uwe, Magner, Jorgen, Royen, Hugo and Martin, Andrew (2016). Membrane distillation pilot plant trials with pharmaceutical residues and energy demand analysis. Chemical Engineering Journal, 306, 471-483. doi: 10.1016/j.cej.2016.07.082

Membrane distillation pilot plant trials with pharmaceutical residues and energy demand analysis

2016

Journal Article

Production of Synthetic Natural Gas from Refuse-Derived Fuel Gasification for Use in a Polygeneration District Heating and Cooling System

Kabalina, Natalia, Costa, Mario, Yang, Weihong and Martin, Andrew (2016). Production of Synthetic Natural Gas from Refuse-Derived Fuel Gasification for Use in a Polygeneration District Heating and Cooling System. Energies, 9 (12) 1080, 1080. doi: 10.3390/en9121080

Production of Synthetic Natural Gas from Refuse-Derived Fuel Gasification for Use in a Polygeneration District Heating and Cooling System

2016

Journal Article

A Comparison of Various Technological Options for Improving Energy and Water Use Efficiency in a Traditional Sugar Mill

Birru, Eyerusalem, Erlich, Catharina, Herrera, Idalberto, Martin, Andrew, Feychting, Sofia, Vitez, Marina, Abdulhadi, Emma Bednarcik, Larsson, Anna, Onoszko, Emanuel, Hallersbo, Mattias, Weilenmann, Louise and Puskoriute, Laura (2016). A Comparison of Various Technological Options for Improving Energy and Water Use Efficiency in a Traditional Sugar Mill. Sustainability, 8 (12) 1227, 1227. doi: 10.3390/su8121227

A Comparison of Various Technological Options for Improving Energy and Water Use Efficiency in a Traditional Sugar Mill

2016

Journal Article

Oral nicotinamide reduces transepidermal water loss: a randomized controlled trial

Chen, A. C., Martin, A. J., Dalziell, R. A., Halliday, G. M. and Damian, D. L. (2016). Oral nicotinamide reduces transepidermal water loss: a randomized controlled trial. British Journal of Dermatology, 175 (6), 1363-1365. doi: 10.1111/bjd.14648

Oral nicotinamide reduces transepidermal water loss: a randomized controlled trial

2016

Journal Article

Long-term outcomes of accelerated BEP (bleomycin, etoposide, cisplatin) for advanced germ cell tumours: updated analysis of an Australian multicentre phase II trial by the Australian and New Zealand Urogenital and Prostate Cancer Trials Group (ANZUP)

Lawrence, N., Martin, A., Toner, G., Stockler, M., Buizen, L., Thomson, D., Gebski, V., Friedlander, M., Yeung, A., Wong, N., Gurney, H., Rosenthal, M., Singhal, N., Kichenadasse, G., Wong, S., Lewis, C., Vasey, P. and Grimison, P. (2016). Long-term outcomes of accelerated BEP (bleomycin, etoposide, cisplatin) for advanced germ cell tumours: updated analysis of an Australian multicentre phase II trial by the Australian and New Zealand Urogenital and Prostate Cancer Trials Group (ANZUP). Annals of Oncology, 27 (12), 2302-2303. doi: 10.1093/annonc/mdw313

Long-term outcomes of accelerated BEP (bleomycin, etoposide, cisplatin) for advanced germ cell tumours: updated analysis of an Australian multicentre phase II trial by the Australian and New Zealand Urogenital and Prostate Cancer Trials Group (ANZUP)

2016

Journal Article

Levator ani trauma and pelvic organ prolapse – a comparison of three translabial ultrasound scoring systems

Trutnovsky, Gerda, Kamisan Atan, Ixora, Ulrich, Daniela, Martin, Andrew and Dietz, Hans P. (2016). Levator ani trauma and pelvic organ prolapse – a comparison of three translabial ultrasound scoring systems. Acta Obstetricia et Gynecologica Scandinavica, 95 (12), 1411-1417. doi: 10.1111/aogs.13018

Levator ani trauma and pelvic organ prolapse – a comparison of three translabial ultrasound scoring systems

2016

Journal Article

Three suturing techniques for closing fusiform excisions. A randomised controlled study

Ling, Nicholas and Martin, Andrew (2016). Three suturing techniques for closing fusiform excisions. A randomised controlled study. Australasian Journal of Dermatology, 57 (4), 271-277. doi: 10.1111/ajd.12359

Three suturing techniques for closing fusiform excisions. A randomised controlled study

2016

Journal Article

Transperineal use of a pocket-sized ultrasound machine vs conventional transvaginal ultrasound: a blinded comparison of cervical length in pregnancy

Wye, D., Woo, J., Mein, B., Magotti, R., Martin, A. and Benzie, R. (2016). Transperineal use of a pocket-sized ultrasound machine vs conventional transvaginal ultrasound: a blinded comparison of cervical length in pregnancy. Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology, 48 (4), 535-536. doi: 10.1002/uog.15861

Transperineal use of a pocket-sized ultrasound machine vs conventional transvaginal ultrasound: a blinded comparison of cervical length in pregnancy

Funding

Current funding

  • 2024 - 2025
    SAFTEP: Semiparametric Accelerated Failure Time Evaluation Project
    Seed Funding for Methodology Research Scheme
    Open grant
  • 2024 - 2026
    Reducing blood culture contamination with the use of a needle-less blood draw device (PIVO Pro): An adaptive group sequential randomized controlled trial (The PIVO Trial)
    Becton, Dickinson and Company
    Open grant

Supervision

Availability

Professor Andrew Martin is:
Available for supervision

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Supervision history

Current supervision

Media

Enquiries

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communications@uq.edu.au