
Overview
Background
Andrew Martin is inaugural Professor of Innovative Clinical Trials and leads the University of Queensland’s cLinical Trials cApability (ULTRA) program. Andrew was Professor in the biostatistics group at the NHMRC Clinical Trials Centre University of Sydney. He maintains that role in an honorary capacity since joining UQ. Prior to academia, Andrew held senior biostatistics roles within research-based pharmaceutical organisations (Pfizer and Roche).
Grants
Category 1: $14.3M Category 3: $131.8M
Grants: 2023 Clinical Trials and Cohort Studies Grant ID 2032441 ($1,362,000): P3BEP Trial - Accelerating First-Line Chemotherapy to Improve Cure Rates for Advanced Germ Cell Tumours; 2022 NHMRC Partnership Projects Grant 2015773 ($1,166,592): Strengthening healthcare systems with Patient Reported Outcome Measures (PROMs); 2020 CA ($600,000): Immuno-metabolic biomarkers for metastatic prostate cancer treatment response; 2018 MRFF Grant APP1170066 ($1,596,631): WHEAT Study on reducing NEC in preterm infants; 2018 CA Grant APP1158397 ($479,375): SCORE trial for shared colorectal cancer care; 2018 CA Grant APP1159837 ($600,000): P3BEP Trial for advanced germ cell tumours; 2018 NHMRC Project Grant APP1159787 ($1,587,163): BCG+MM Trial for bladder cancer; 2016 Victorian Cancer ($300,000): SCORE project on shared care of Colorectal cancer survivors; 2015 CA Priority-driven Collaborative Cancer Research Scheme ($443,307): LEAD - Lung cancer diagnostic and treatment pathways; 2015 NHMRC Project Grant 1108328 ($624,824): Oral Nicotinamide for skin cancer chemoprevention after Transplant; 2014 Co-funded Grant 1079794 ($597,095): Methoxyflurane to reduce discomfort of prostate biopsy; 2013 NHMRC Project Grant 1064121 ($880,425): CHEST Australia project for quicker primary care consultations in lung cancer; 2012 NHMRC Project Grant APP1047100 ($2,203,171): Bovine lactoferrin study on low birthweight infants; 2011 National Breast Cancer Foundation ($199,606): Physical well-being for metastatic breast cancer; 2011 NHMRC Project Grant 1028555 ($187,018): Evidence on reduced child obesity rates; 2011 NHMRC Project Grant 1026977 ($586,691): Oral nicotinamide for skin cancer prevention; 2011 Australasian College of Dermatologists grant ($25,000): Nicotinamide for non-melanoma skin cancer in renal transplant recipients; 2010 NHMRC Project Grant 1007628 ($369,208): NEU-HORIZONS study on riluzole for oxaliplatin neurotoxicity; 2010 NHMRC Project Grant 1003414 ($564,410): Phase II prostate cancer follow-up trial in primary care.
Statistical lead on the following projects receiving industry funding with USyd as administering institution: ENZARAD NCT02446444 ($12,178,000); ENZAMET NCT02446405 ($20,408,129); INTEGRATE ACTRN12612000239864 ($6,900,000); INTEGRATE IIa ACTRN12616000420448 ($22,264,248); INTEGRATE IIb NCT04879368 ($36,330,215); DASL-HiCaP NCT04136353 ($33,777,579).
Availability
- Professor Andrew Martin is:
- Available for supervision
Research impacts
Research Achievements and Collaborations: Has made original, innovative, and distinguished contributions to methodological research, as well as the design, conduct, analysis, interpretation, and dissemination of clinical research that has had an impact at an international level policy, practice, and subsequent research programs. Has been responsible for the provision of statistical leadership to collaborative trials groups to design, undertake, analyse, and report on clinical trials, as well as promoting investigator-initiated research activities. 2020-2024 Scopus/SciVal author publication metrics: FWCI of 5.21, 51% in top 10% most cited worldwide, 39% international collaboration 3,763 citations (10,934 overall). Received the 2020 ACTA (Australian Clinical Trials Alliance) Statistics in Trials Interest Group Excellence in Trial Statistics Award for ENZAMET Trial. Research funding in last 5 years: $3.1M category 1 and $76.7M category 3.
Contributions to the Field: Led methodological research with international impact. Examples in the last 5 years focus on the topic of changes to the design of ongoing trials. This work has been cited in the CONSERVE 2021 Statement (JAMA. 2021;326(3):257-265 FWCI 7.38; top 1% of general medical journals). Also co-published innovative method for appropriately adjusting estimates of effect obtained from trials that terminate early based on the results of an interim analysis (Statistical Methods in Medical Research – top 11% for statistics journals). Co-designed andled the statistical aspects of design, conduct, analysis, and interpretation of many trial. Two key examples in the last 5 years include ENZAMET and TheraP. (1) ENZAMET study selected for plenary presentation at ASCO (peak international clinical oncology conference attended by over 30,000 international delegates). Am second author for both main N Engl J Med paper (2019;381:121) (journal ranked top 1% general medicine), the quality of life J Clin Oncol paper (2022;40:837-46) (journal ranked top 2% cancer research), and the follow-up Lancet Oncol paper (2022;23:1389) (journal ranked top 1% cancer research). Results were used in support of successful registration of enzalutamide with US FDA in this indication and have been incorporated into US and European treatment guidelines. (2) TheraP evaluated efficacy of cutting-edge targeted radiopharmaceutical (Lu-PSMA) in advance prostate cancer that delivers radiation to cells expressing the prostate-specific membrane antigen. Selected for oral presentation at highly prestigious ASCO 2020 and ASCO GU 2021 conferences. Second senior author of The Lancet paper (2021;397:797) (journal ranked top 1% general medicine). Has led to 2 additional RCTs of Lu-PSMA that I co-designed. One (ENZA-p) was just published in Lancet Oncol (2024 Apr 12:S1470-2045(24)00135-9) (journal ranked top 1% cancer research).
Works
Search Professor Andrew Martin’s works on UQ eSpace
2014
Journal Article
Protocol for the ProCare Trial: A phase II randomised controlled trial of shared care for follow-up of men with prostate cancer
Emery, Jon, Doorey, Juanita, Jefford, Michael, King, Madeleine, Pirotta, Marie, Hayne, Dickon, Martin, Andrew, Trevena, Lyndal, Lim, Tee, Constable, Roger, Hawks, Cynthia, Hyatt, Amelia, Hamid, Akhlil, Violet, John, Gill, Suki, Frydenberg, Mark and Schofield, Penelope (2014). Protocol for the ProCare Trial: A phase II randomised controlled trial of shared care for follow-up of men with prostate cancer. BMJ Open, 4 (3) e004972, 1-10. doi: 10.1136/bmjopen-2014-004972
2014
Journal Article
The relationships between obsessive-compulsive symptom dimensions and cognitions in obsessive-compulsive disorder
Brakoulias, Vlasios, Starcevic, Vladan, Berle, David, Milicevic, Denise, Hannan, Anthony and Martin, Andrew (2014). The relationships between obsessive-compulsive symptom dimensions and cognitions in obsessive-compulsive disorder. Psychiatric Quarterly, 85 (2), 133-142. doi: 10.1007/s11126-013-9278-y
2014
Conference Publication
The use of 3-dimensional ultrasound of the pelvic floor to predict recurrence risk after pelvic reconstructive surgery
Rodrigo, Natassia, Wong, Vivien, Shek, Ka Lai, Martin, Andrew and Dietz, Hans Peter (2014). The use of 3-dimensional ultrasound of the pelvic floor to predict recurrence risk after pelvic reconstructive surgery. Blackwell Publishing. doi: 10.1111/ajo.12171
2013
Journal Article
Performance of the Parent Report of Children's Abilities-Revised (PARCA-R) versus the Bayley Scales of Infant Development III
Martin, Andrew J., Darlow, Brian A., Salt, Alison, Hague, Wendy, Sebastian, Lucille, McNeill, Nicki and Tarnow-Mordi, William (2013). Performance of the Parent Report of Children's Abilities-Revised (PARCA-R) versus the Bayley Scales of Infant Development III. Archives of Disease in Childhood, 98 (12), 955-958. doi: 10.1136/archdischild-2012-303288
2013
Journal Article
The median informs the message: accuracy of individualized scenarios for survival time based on oncologists' estimates
Kiely, Belinda E., Martin, Andrew J., Tattersall, Martin H. N., Nowak, Anna K., Goldstein, David, Wilcken, Nicholas R. C., Wyld, David K., Abdi, Ehtesham A., Glasgow, Amanda, Beale, Philip J., Jefford, Michael, Glare, Paul A. and Stockler, Martin R. (2013). The median informs the message: accuracy of individualized scenarios for survival time based on oncologists' estimates. Journal of Clinical Oncology, 31 (28), 3565-3572. doi: 10.1200/JCO.2012.44.7821
2013
Journal Article
Balloon warming time is the strongest predictor of late pulmonary vein electrical reconnection following cryoballoon ablation for atrial fibrillation
Ghosh, Justin, Martin, Andrew, Keech, Anthony C., Chan, Kim H., Gomes, Sean, Singarayar, Suresh and McGuire, Mark A. (2013). Balloon warming time is the strongest predictor of late pulmonary vein electrical reconnection following cryoballoon ablation for atrial fibrillation. Heart Rhythm, 10 (9), 1311-1317. doi: 10.1016/j.hrthm.2013.06.014
2013
Journal Article
Can urodynamic stress incontinence be diagnosed by ultrasound?
Dietz, H. P., Nazemian, K., Shek, K. L. and Martin, A. (2013). Can urodynamic stress incontinence be diagnosed by ultrasound?. International Urogynecology Journal and Pelvic Floor Dysfunction, 24 (8), 1399-1403. doi: 10.1007/s00192-012-2032-4
2013
Journal Article
Human papillomavirus, smoking status and outcomes in tonsillar squamous cell carcinoma
Hong, Angela M., Martin, Andrew, Chatfield, Mark, Jones, Deanna, Zhang, Mei, Armstrong, Bruce, Lee, C. Soon, Harnett, Gerald, Milross, Christopher, Clark, Jonathan, Elliott, Michael, Smee, Robert, Corry, June, Liu, Chen, Porceddu, Sandro, Rees, Guy and Rose, Barbara (2013). Human papillomavirus, smoking status and outcomes in tonsillar squamous cell carcinoma. International Journal of Cancer, 132 (12), 2748-2754. doi: 10.1002/ijc.27956
2013
Journal Article
Hypertensive disease of pregnancy is associated with decreased risk for respiratory distress syndrome in moderate preterm neonates
Liu, Anthony, Carlsson, Eva, Nilsson, Sofia, Oei, Julee, Bajuk, Barbara, Peek, Michael, Martin, Andrew and Nanan, Ralph (2013). Hypertensive disease of pregnancy is associated with decreased risk for respiratory distress syndrome in moderate preterm neonates. Hypertension in Pregnancy, 32 (2), 169-177. doi: 10.3109/10641955.2013.784786
2013
Journal Article
Risk assessment to guide prostate cancer screening decisions: A cost-effectiveness analysis
Martin, Andrew J., Lord, Sarah J., Verry, Hannah E., Stockler, Martin R. and Emery, Jon D. (2013). Risk assessment to guide prostate cancer screening decisions: A cost-effectiveness analysis. Medical Journal of Australia, 198 (10), 546-550. doi: 10.5694/mja12.11597
2013
Journal Article
Pelvic floor dysfunction-Does menopause duration matter?
Trutnovsky, Gerda, Guzman-Rojas, Rodrigo, Martin, Andrew and Dietz, Hans P. (2013). Pelvic floor dysfunction-Does menopause duration matter?. Maturitas, 76 (2), 134-138. doi: 10.1016/j.maturitas.2013.06.012
2013
Journal Article
Human papillomavirus modifies the prognostic significance of T stage and possibly N stage in tonsillar cancer
Hong, A. M., Martin, A., Armstrong, B. K., Lee, C. S., Jones, D., Chatfield, M. D., Zhang, M., Harnett, G., Clark, J., Elliott, M., Milross, C., Smee, R., Corry, J., Liu, C., Porceddu, S., Vaska, K., Veness, M., Morgan, G., Fogarty, G., Veivers, D., Rees, G. and Rose, B. (2013). Human papillomavirus modifies the prognostic significance of T stage and possibly N stage in tonsillar cancer. Annals of Oncology, 24 (1) mds205, 215-219. doi: 10.1093/annonc/mds205
2013
Journal Article
The use of psychotropic agents for the symptoms of obsessive-compulsive disorder
Brakoulias, Vlasios, Starcevic, Vladan, Berle, David, Milicevic, Denise, Moses, Karen, Hannan, Anthony, Sammut, Peter and Martin, Andrew (2013). The use of psychotropic agents for the symptoms of obsessive-compulsive disorder. Australasian Psychiatry, 21 (2), 117-121. doi: 10.1177/1039856212470502
2013
Journal Article
Further support for five dimensions of obsessive-compulsive symptoms
Brakoulias, Vlasios, Starcevic, Vladan, Berle, David, Sammut, Peter, Milicevic, Denise, Moses, Karen, Hannan, Anthony and Martin, Andrew (2013). Further support for five dimensions of obsessive-compulsive symptoms. Journal of Nervous and Mental Disease, 201 (6), 452-459. doi: 10.1097/NMD.0b013e318294804e
2013
Journal Article
The characteristics of unacceptable/taboo thoughts in obsessive-compulsive disorder
Brakoulias, Vlasios, Starcevic, Vladan, Berle, David, Milicevic, Denise, Moses, Karen, Hannan, Anthony, Sammut, Peter and Martin, Andrew (2013). The characteristics of unacceptable/taboo thoughts in obsessive-compulsive disorder. Comprehensive Psychiatry, 54 (7), 750-757. doi: 10.1016/j.comppsych.2013.02.005
2012
Journal Article
A phase II clinical trial of a dental health education program delivered by aboriginal health workers to prevent early childhood caries
Blinkhorn, Fiona, Brown, Ngiare, Freeman, Ruth, Humphris, Gerry, Martin, Andrew and Blinkhorn, Anthony (2012). A phase II clinical trial of a dental health education program delivered by aboriginal health workers to prevent early childhood caries. BMC Public Health, 12 (1) 681. doi: 10.1186/1471-2458-12-681
2012
Journal Article
Determination of postvoid residual by translabial ultrasound
Dietz, H. P., Velez, D., Shek, K. L. and Martin, A. (2012). Determination of postvoid residual by translabial ultrasound. International Urogynecology Journal and Pelvic Floor Dysfunction, 23 (12), 1749-1752. doi: 10.1007/s00192-012-1769-0
2012
Journal Article
Comparison of maternal abdominal subcutaneous fat thickness and body mass index as markers for pregnancy outcomes: A stratified cohort study
Suresh, Ashwin, Liu, Anthony, Poulton, Alison, Quinton, Ann, Amer, Zara, Mongelli, Max, Martin, Andrew, Benzie, Ronald, Peek, Michael and Nanan, Ralph (2012). Comparison of maternal abdominal subcutaneous fat thickness and body mass index as markers for pregnancy outcomes: A stratified cohort study. Australian and New Zealand Journal of Obstetrics and Gynaecology, 52 (5), 420-426. doi: 10.1111/j.1479-828X.2012.01471.x
2012
Journal Article
Impaired fetal thymic growth precedes clinical preeclampsia: A case-control study
Eviston, David P., Quinton, Ann E., Benzie, Ron J., Peek, Michael J., Martin, Andrew and Nanan, Ralph K. (2012). Impaired fetal thymic growth precedes clinical preeclampsia: A case-control study. Journal of Reproductive Immunology, 94 (2), 183-189. doi: 10.1016/j.jri.2012.04.001
2012
Conference Publication
Usefulness of medical oncologists' estimates of survival time in people with advanced cancer
Kiely, Belinda E., Martin, Andrew J., Tattersall, Martin H. N., Nowak, Anna K., Goldstein, David, Wilcken, Nicholas, Wyld, David, Beale, Philip James, Jefford, Michael, Glasgow, Amanda L., Abdi, Ehtesham A., Glare, Paul A. and Stockler, Martin R. (2012). Usefulness of medical oncologists' estimates of survival time in people with advanced cancer. 48th Annual Meeting of the American-Society-of-Clinical-Oncology (ASCO), Chicago, IL USA, 1-6 June 2012. Alexandria, VA USA: American Society of Clinical Oncology.
Funding
Current funding
Supervision
Availability
- Professor Andrew Martin is:
- Available for supervision
Before you email them, read our advice on how to contact a supervisor.
Supervision history
Current supervision
-
Doctor Philosophy
Advanced methods for biomarker informed endometrial cancer
Associate Advisor
Other advisors: Dr Eva Baxter, Dr Zoe West, Professor Andreas Obermair
Media
Enquiries
For media enquiries about Professor Andrew Martin's areas of expertise, story ideas and help finding experts, contact our Media team: