Overview
Background
I am a registered medical practitioner with a PhD from The University of Queensland. My doctoral work was in the field of population health, and focused on the use of N-of-1 trial methodology in clinical practice. I have two major research areas: N-of-1 trials/Single Case Experimental Designs (SCEDs), and whiplash and other musculoskeletal pain after Road Traffic Crashes.
I played a key role in setting up and sustaining UQ’s N-of-1 trials Unit since 1998, and am a key driver of its success, resulting in UQ becoming a world leader in N-of-1 trials since 2009. . Building on my 20 year clinical research career at UQ, I lead the research program at UQCCR in N-of-1 trials, and am a recognised leader in this field both in Australia and internationally. In addition, my skills include trial design and management more broadly.
I am also working at Recover Injury Research Centre in the field of recovery following Road Traffic injuries. Within the Designing Better Therapies research program, my main focus is on improving early management and reducing opioid prescribing for minor musculoskeletal injuries after Road Traffic Crashes. My other area of research is in applying Single Case Experimental Designs to work towards better therapies after injury, especially when caused by Road Traffic Crashes.
Availability
- Associate Professor Jane Nikles is:
- Available for supervision
- Media expert
Qualifications
- Bachelor of Medicine and Surgery and Medical Science, The University of Queensland
- Doctor of Philosophy, The University of Queensland
Research interests
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Clinical trials, n-of-1 trials, research methodology, personalised medicine, individual treatments
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Single Case Experimental Designs
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Whiplash, minor musculoskeletal injury, opioid prescribing
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ADHD, children, sleep
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Melatonin
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Parkinson's Disease
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Skin cancer prevention, improving children's sun protection practices
Works
Search Professor Jane Nikles’s works on UQ eSpace
2000
Conference Publication
Consumer perspectives of individualised medication effectiveness tests in General Practices
Nikles, J., Del Mar, C., Glasziou, P., Clavarino, A. and Duggan, C. (2000). Consumer perspectives of individualised medication effectiveness tests in General Practices. General Practice Evaluation Program Conference, Hobart , TAS, Australia, 2000.
2000
Conference Publication
Consumer perspectives of single patient trials in general practice
Clavarino, A. M., Del Mar, C. B., Duggan, C. M., Glasziou, P. P. and Nikles, C. J. (2000). Consumer perspectives of single patient trials in general practice. The General Practice Evaluation Program, Hobart: Hotel Grand Chancellor, 4-5 May 2000. Canberra: National Information Service.
2000
Conference Publication
Single patient trials of stimulants in Attention Deficit Hyperactivity Disorder - a pilot study
Mitchell, G., Nikles, J., Glasziou, P. and Schluter, P. (2000). Single patient trials of stimulants in Attention Deficit Hyperactivity Disorder - a pilot study. 6th European Wonca Conference on General Practice & Family Doctors, Hafburg Conference Centre, Vienna, 2 - 6 July 2000. Euopean WONCA.
1999
Conference Publication
Single patient trials in general practice
Nikles, C. J., Glasziou, P. P. and Del Mar, C. B. (1999). Single patient trials in general practice. General Practice Evaluation Program Conference, Sheraton, Brisbane, 6-7 May 1999. Bedford Park SA: Flinders Uni.
1999
Conference Publication
Individualised medication effectiveness tests in general practice
Nikles, J., Glasziou, P. and Del Mar, C. (1999). Individualised medication effectiveness tests in general practice. General Practice Evaluation Program Conference, Brisbane, QLD, Australia, 1999.
1984
Journal Article
Infections in renal transplant recipients
Hardie, I. R., Moses, D. and Nikles, J. (1984). Infections in renal transplant recipients. Transplantation Proceedings, 16 (4), 988-989.
1983
Conference Publication
Infections in renal transplant recipients
Moses, Diana, Nikles, Jane, Leong, Geoff and Hardie, Ian (1983). Infections in renal transplant recipients. Meeting of the Surgical Research Society of Australasia, Perth, Western Australia, 14-16 October 1982. Richmond, VIC, Australia: Wiley-Blackwell Publishing. doi: 10.1111/j.1445-2197.1983.tb02463.x
Funding
Current funding
Supervision
Availability
- Associate Professor Jane Nikles is:
- Available for supervision
Before you email them, read our advice on how to contact a supervisor.
Available projects
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Opioid use and misuse following road traffic musculoskeletal injury
Recent research by our group has shown that opioids are inappropriately prescribed for people with musculoskeletal pain after a road traffic crash. This project will explore this issue by longitudinal investigation of opioid use after injury and by using qualitative methods to explore reasons underlying opioid use in injured people and health care providers. It will also explore the physiotherapist's role in preventing opioid misuse.
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N-of-1 trials in health care, melatonin, complementary and alternative medicines.
N-of-1 trials in health care, melatonin, complementary and alternative medicines.
Projects available mostly on clinical neuroscience topics – eg sleep, pain – but discussion on other topics welcome.
Please contact me on uqjnikle@uq.edu.au to discuss several available projects.
Supervision history
Completed supervision
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2019
Doctor Philosophy
N-of-1 Trials as a Bioequivalence Method to assess local medicines in resources limited countries: the case of Anti-hypertensive Medicines in Ethiopia
Associate Advisor
Media
Enquiries
Contact Associate Professor Jane Nikles directly for media enquiries about:
- ADHD
- children
- Clinical trials
- General practice research
- individualised treatments
- melatonin
- N-of-1 trials
- Parkinson's Disease
- Personalised medicine
- Single Case Experimental Designs
- sleep
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