Overview
Background
I am a registered medical practitioner with a PhD from The University of Queensland. My doctoral work was in the field of population health, and focused on the use of N-of-1 trial methodology in clinical practice. I have two major research areas: N-of-1 trials/Single Case Experimental Designs (SCEDs), and whiplash and other musculoskeletal pain after Road Traffic Crashes.
I played a key role in setting up and sustaining UQ’s N-of-1 trials Unit since 1998, and am a key driver of its success, resulting in UQ becoming a world leader in N-of-1 trials since 2009. . Building on my 20 year clinical research career at UQ, I lead the research program at UQCCR in N-of-1 trials, and am a recognised leader in this field both in Australia and internationally. In addition, my skills include trial design and management more broadly.
I am also working at Recover Injury Research Centre in the field of recovery following Road Traffic injuries. Within the Designing Better Therapies research program, my main focus is on improving early management and reducing opioid prescribing for minor musculoskeletal injuries after Road Traffic Crashes. My other area of research is in applying Single Case Experimental Designs to work towards better therapies after injury, especially when caused by Road Traffic Crashes.
Availability
- Associate Professor Jane Nikles is:
- Available for supervision
- Media expert
Qualifications
- Bachelor of Medicine and Surgery and Medical Science, The University of Queensland
- Doctor of Philosophy, The University of Queensland
Research interests
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Clinical trials, n-of-1 trials, research methodology, personalised medicine, individual treatments
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Single Case Experimental Designs
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Whiplash, minor musculoskeletal injury, opioid prescribing
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ADHD, children, sleep
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Melatonin
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Parkinson's Disease
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Skin cancer prevention, improving children's sun protection practices
Works
Search Professor Jane Nikles’s works on UQ eSpace
2002
Conference Publication
Individualised medication effectiveness tests may improve osteoarthritis management and decrease NSAID expenditure
Nikles, J., Glasziou, P., Del Mar, C., Duggan, C., Yelland, M. and King, J. (2002). Individualised medication effectiveness tests may improve osteoarthritis management and decrease NSAID expenditure. Quality Use of Medicines Conference, Canberra ACT, Australia, 2002.
2001
Conference Publication
Individualised medication effectiveness tests of valerian for chronic insomnia
Nikles, J.C.J., Coxeter, P.D., Price, J., Duggan, C. M., Glasziou, P. P., Del Mar, C. B. and Schluter, P. J. (2001). Individualised medication effectiveness tests of valerian for chronic insomnia. General Practice & Primary Health Care Research Conference, Adelaide, South Australia, 31 May - 1 June 2001. Adelaide, South Australia:
2001
Conference Publication
Research as practice: using Individialised Medication Effectiveness tests to improve prescribing
Nikles, J.C.J., Duggan, C. M., Glasziou, P. P., Del Mar, C. B., Coxeter, P.D., Askew, D. A., Janamian, T., Spinks, A. B., Clavarino, A. M., Mitchell, G. K., O'Connor, V. M., Price, J., Yelland, M. J. and Schluter, P. J. (2001). Research as practice: using Individialised Medication Effectiveness tests to improve prescribing. 2001 General Practice and Primary Health Care Research Conference & Australian Association of Academic General Practice Research Meeting 2001, Canberra, 31 May - 1 June 2001. Canberra: Primary Health Care Research & Information Service.
2001
Conference Publication
Individualised medication effectiveness tests to better manage ADHD
Mitchell, G., Duggan, C., Glasziou, P., Del Mar, C., Nikles, J., Janamian, T. and Schluter, P (2001). Individualised medication effectiveness tests to better manage ADHD. General Practice Evaluation Program Conference, Adelaide, South Australia, 2001.
2001
Conference Publication
Do psychological menopausal symptoms respond to HRT? Individualised medication effectiveness tests as an applied research tool
O'Connor, V., Askew, D., Spinks, A., Nikles, J., Duggan, C., Del Mar, C. and Glasziou, P. (2001). Do psychological menopausal symptoms respond to HRT? Individualised medication effectiveness tests as an applied research tool. General Practice Evaluation Program Conference, Adelaide, South Australia, 2001.
2001
Conference Publication
Do psychological menopausal symptoms respond to HRT Individualised Medication Effectiveness Tests as an applied research tool
O'Connor, V. M., Askew, D. A., Spinks, A. B., Nikles, J.C.J., Duggan, C. M., Del Mar, C. B. and Glasziou, P. P. (2001). Do psychological menopausal symptoms respond to HRT Individualised Medication Effectiveness Tests as an applied research tool. General Practice & Primary Health Care Research Conference, Adelaide, Australia, 31 May - 1 June 2001. Adelaide:
2001
Conference Publication
Individualised Medication Effectiveness Tests to better manage ADHD
Mitchell, G. K., Duggan, C. M., Glasziou, P. P., Del Mar, C. B., Nikles, J.C.J., Janamian, T. and Schluter, P. J. (2001). Individualised Medication Effectiveness Tests to better manage ADHD. 2001 General Practice and Primary Health Care Research Conf, Canberra, 31 May - 1 June 2001. Canberra: Primary Health Care Research & Information Service.
2001
Conference Publication
Individualised medication effectiveness tests of valerian for chronic insomnia
Nikles, J., Coxeter, P., Price, J., Duggan, C., Glasziou, P., Del Mar, C. and Schluter, P. (2001). Individualised medication effectiveness tests of valerian for chronic insomnia. General Practice Evaluation Program Conference, Adelaide, South Australia, 2001.
2001
Conference Publication
Research as practice: using individualised medication effectiveness tests to improve prescribing
Nikles, J., Duggan, C., Glasziou, P., Del Mar, C., Coxeter, P., Askew, D., Janamian, T., Spinks, A., Clavarino, A., Mitchell, G., O'Connor, V., Price, J., Yelland, M. and Schluter, P. (2001). Research as practice: using individualised medication effectiveness tests to improve prescribing. General Practice Evaluation Program Conference, Adelaide, SA, Australia, 2001.
2001
Conference Publication
Individualised medication effectiveness tests may improve OA management and decrease NSAID expenditure
Nikles, J.C.J., Duggan, C. M., Glasziou, P. P., Del Mar, C. B. and Yelland, M. J. (2001). Individualised medication effectiveness tests may improve OA management and decrease NSAID expenditure. General Practice & Primary Health Care Research Conference, Adelaide, South Australia, 31 May - 1 June 2001. Adelaide, South Australia:
2001
Conference Publication
Research as practice: using Individualised medication effectiveness tests to improve prescribing
Nikles, J., Glasziou, P., Del Mar, C., Duggan, C., Mitchell, G., O'Connor, V., Price, J., Yelland, M., Coxeter, P., Askew, D., Janamian, T., Spinks, A., Clavarino, A. and Schluter, P. (2001). Research as practice: using Individualised medication effectiveness tests to improve prescribing. General Practice and Primary Health Care conference, Brisbane, QLD, Australia, 2001.
2001
Conference Publication
Individualised medication effectiveness tests may improve OA management and decrease NSAID expenditure
Nikles, J., Duggan, C., Glasziou, P., Del Mar, C. and Yelland, M. (2001). Individualised medication effectiveness tests may improve OA management and decrease NSAID expenditure. General Practice Evaluation Program Conference, Adelaide, South Australia, 2001.
2000
Conference Publication
Single patient trials of stimulants in Attention Deficit Hyperactivity Disorder
Mitchell, G. K., Nikles, C. J., Glasziou, P. P. and Schluter, P. J. (2000). Single patient trials of stimulants in Attention Deficit Hyperactivity Disorder. General Practice Evaluation Conference, Flinders University, Adelaide, Australia, 2000. Adelaide: Flinders University.
2000
Conference Publication
Is a individualised medication effectiveness tests service feasible in general practice? Preliminary experiences
Nikles, J., Glasziou, P., Del Mar, C., Duggan, C., Clavarino, A. and Yelland, M. (2000). Is a individualised medication effectiveness tests service feasible in general practice? Preliminary experiences. General Practice Evaluation Program Conference, Hobart , TAS, Australia, 2000.
2000
Conference Publication
Single patient trials in the treatment of ADHD in General Practice - a pilot study
Mitchell, G. K., Glasziou, P. P. and Nikles, C. J. (2000). Single patient trials in the treatment of ADHD in General Practice - a pilot study. 6th European Conference on General Practice and Family Medicine, Vienna; Hafburg Conference Centre, Vienna, 2-6 July 2000. Vienna: WONCA.
2000
Conference Publication
Individualised medication effectiveness tests service: feasibility in general practice
Nikles, J., Glasziou, P., Del Mar, C., Duggan, C., Askew, D., Janamian, T. and Coxeter, P. (2000). Individualised medication effectiveness tests service: feasibility in general practice. RACGP 43rd Annual Scientific Convention, Townsville, QLD, Australia, 2000.
2000
Conference Publication
Single patient trials of stimulants in Attention Deficit Hyperactivity Disorder - a pilot study
Mitchell, G. K., Nikles, C. J., Glasziou, P. P. and Schluter, P. J. (2000). Single patient trials of stimulants in Attention Deficit Hyperactivity Disorder - a pilot study. 29th Annual Scientific Meeting Association of University Departments of General Practice, Bournemouth, England., 2000. England: Association of University Departments of General Practice.
2000
Conference Publication
Preliminary experience with single patient trials in general practice
Glasziou, P. P., Del Mar, C. B., Nikles, C. J. and Duggan, C. M. (2000). Preliminary experience with single patient trials in general practice. The 2000 General Practice Evaluation Program, Hobart, 2000. Canberra: National Information Service.
2000
Conference Publication
Consumer perspectives of individualised medication effectiveness tests in General Practices
Nikles, J., Del Mar, C., Glasziou, P., Clavarino, A. and Duggan, C. (2000). Consumer perspectives of individualised medication effectiveness tests in General Practices. General Practice Evaluation Program Conference, Hobart , TAS, Australia, 2000.
2000
Conference Publication
Consumer perspectives of single patient trials in general practice
Clavarino, A. M., Del Mar, C. B., Duggan, C. M., Glasziou, P. P. and Nikles, C. J. (2000). Consumer perspectives of single patient trials in general practice. The General Practice Evaluation Program, Hobart: Hotel Grand Chancellor, 4-5 May 2000. Canberra: National Information Service.
Funding
Current funding
Supervision
Availability
- Associate Professor Jane Nikles is:
- Available for supervision
Before you email them, read our advice on how to contact a supervisor.
Available projects
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Opioid use and misuse following road traffic musculoskeletal injury
Recent research by our group has shown that opioids are inappropriately prescribed for people with musculoskeletal pain after a road traffic crash. This project will explore this issue by longitudinal investigation of opioid use after injury and by using qualitative methods to explore reasons underlying opioid use in injured people and health care providers. It will also explore the physiotherapist's role in preventing opioid misuse.
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N-of-1 trials in health care, melatonin, complementary and alternative medicines.
N-of-1 trials in health care, melatonin, complementary and alternative medicines.
Projects available mostly on clinical neuroscience topics – eg sleep, pain – but discussion on other topics welcome.
Please contact me on uqjnikle@uq.edu.au to discuss several available projects.
Supervision history
Completed supervision
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2019
Doctor Philosophy
N-of-1 Trials as a Bioequivalence Method to assess local medicines in resources limited countries: the case of Anti-hypertensive Medicines in Ethiopia
Associate Advisor
Media
Enquiries
Contact Associate Professor Jane Nikles directly for media enquiries about:
- ADHD
- children
- Clinical trials
- General practice research
- individualised treatments
- melatonin
- N-of-1 trials
- Parkinson's Disease
- Personalised medicine
- Single Case Experimental Designs
- sleep
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