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My research interests are at the intersection of plant developmental genetics, functional genomics, and molecular and systems biology, following my doctoral and postdoctoral training in the USA. The research effort in my group is focused on harnessing transformative genomics technology to understand the genetics of plant development, and to discover regulatory mechanisms coordinating plant growth and development. We utilize a variety of plant species in our research, from the model plant organism Arabidopsis to grain and horticultural crops like wheat, mango, avocado and macadamia. We employ a range of techniques based on high throughout DNA sequencing to explore gene expression, chromatin accessibility and chromatin modifications from single cell to whole plant levels, bioinformatics and computational biology tools to infer genetic components of gene regulatory networks, as well as gene editing technology to evaluate phenotypic consequences of perturbations in gene regulatory networks.

Protein trafficking in disease

The highly co-ordinated movement of the thousands of distinct membrane proteins between the cell surface and intracellular compartments is a critical factor in health and disease. This movement controls the organisation of cells in tissues and communication between cells and their environment. The success of this process depends on the regulated sorting and trafficking of proteins within the highly dynamic endosomal compartments of the cell in processes that are emerging as important drivers of neurodegenerative disease, cancer and metabolic pathologies. An understanding of how endosomal traffic is regulated, and how lysosomal traffic and degradation are modulated, is critical for providing insights into disease and devising new therapeutic approaches.

Major Undergraduate Teaching Activity

SBMS Honours Coordinator (BIOM6200)

BIOL2200 – Molecular Cell Biology I Lecturer and practical cooridinator

BIOL3006 – Molecular Cell Biology II Lecturer

Student Supervisor for Research Projects in Biomedical Sciences (SCIE3220/1 or Honours)

Valerio's current research is focused on coastal conservation and restoration. His work supports the Nature Repair Market (NRM) established by the Department of Climate Change, Energy, Environment, and Water (DCCEEW) and encompasses facilitating expert collaboration, developing best-practice guidelines for biodiversity assessment, and informing evidence-based policy for coastal restoration. He is also involved in the development of methods to assess biodiversity gains through time on oyster reef restoration projects using environmental DNA.

Originally from Ticino, an Italian-speaking region of Switzerland, Valerio had formerly a background in neuroengineering and molecular biology. He completed his BSc in Biology at the University of Lausanne (UNIL), Switzerland, and his MSc in Biology (with a focus on neuroscience) at the Swiss Federal Institute of Technology in Zurich (ETHZ), Switzerland. Despite growing up in the middle of the Alps, he has always had a fascination with marine life, which brought him to the University of Queensland to undertake his Master’s thesis as part of the Sensory Neurobiology group, studying the visual system of surgeonfish. Valerio completed his PhD as part of the Marine Sensory Ecology Lab at the University of Queensland, where he researched the development of colour vision and colouration in a coral reef fish family, applying cutting-edge technology such as CRISPR-Cas9 and single cell RNA sequencing, while also using behaviour paradigms, calibrated photography, phylogenetic comparative methods and bioinformatics.

I grew up on the Devon coast hunting among the fucoids for crabs and shrimp. I undertook research while at school on the diet of blennies. At university in Swansea, south Wales, and as a marine Biology student I investigated informally the behaviour of intertidal pool dwelling organisms andmore formally (Hons) the ecology of benthic invertebrates. My PhD at the University of Queensland delved into the ecology and evolution of halfbeaks (Hemiramphidae) . My research track-record since reflects both my early interests and those developed subsequent to my PhD. I have published in diverse fields reflecting my general curiosity about marine life, and in particular the dynamic between evolution and action addressing challenges to extant paradigms that my extensive time in the field have prompted.

Professor Alan Tilbrook is nationally and internationally recognised for leading scientific research in animal science and biomedical science (endocrinology, neuroendocrinology, behaviour, stress, and reproduction). He is a global leader in animal welfare science. Professor Tilbrook has an outstanding balanced portfolio in leadership, strategic planning, research, academia, education and government. He is Professor of Animal Welfare in the School of Veterinary Science and has an affiliate appointment in the Centre for Animal Science, Queensland Alliance for Agriculture and Food Innovation at The University of Queensland. Professor Tilbrook is one of three expert members of a Strategy Advisory Group to provide expert strategic advice to the Department of Agriculture, Fisheries and Forestry to assist the development of the renewed Australian Animal Welfare Strategy. He represents Universities Australia on the Board of the Australian and New Zealand Council for the Care of Animals in Research and Teaching, represents The University of Queensland on the World Organisation for Animal Health and is a member of the Australian Government’s Live Export Animal Welfare Advisory Group. Professor Tilbrook was Chair and Research Champion of the National Primary Industries Animal Welfare Research, Development and Extension Strategy from 2013 to 2025. He established The Animal Welfare Collaborative, a university-facilitated network of individuals, companies, and organisations working together to make evidence-based improvements in animal welfare. This was a collaborative venture with The University of Newcastle, The University of Western Australia and The University of Adelaide. He was a founder, Deputy Director and Co-Director of the Animal Welfare Science Centre, was the Research Chief of Livestock and Farming Systems at the South Australian Research and Development Institute and was Deputy Head of the Department of Physiology at Monash University. He has held numerous national and local leadership roles. Professor Tilbrook's research is conceptually driven with a multidisciplinary and integrative approach. He has developed cutting edge research programs across a range of species including sheep, pigs, poultry, cattle, goats, rodents, horses, buffalo and humans. Professor Tilbrook places a huge emphasis on collaboration, training and professional development.

Dr Mauro Torres is a Lecturer in the School of Chemical Engineering at the University of Queensland, and leads a research group working at the interface of engineering and biology. designing living cells so that they behave in reliable, controllable ways

Background

Many of our most important medicines are made by cells, and a growing number of new treatments are living cells. Dr Torres's research changes how cells work by engineering the molecular mechanisms controlling how cells grow, produce therapeutic products, and respond to their surroundings, so they can be put to use more effectively. The same set of tools applies across very different goals: 1) Make biological medicines more efficiently, 2) Build cells that act as effective therapeutics, and 3) Develop tools for controlling gene expression. These goals focus of transforming how we make protein-, cell and gene therapeutics.

Dr Torres holds a PhD in Molecular Biology at the University of Manchester, and undergraduate in Chemical Engineering. His interdisciplinary background defines his approach to problems spanning the two fields. Before joining UQ, he was awarded a Leverhulme Trust Early Career Fellowship, which supported the establishment of his independent research group at Manchester. His current programme extends these principles to synthetic biology and to the engineering of cells for manufacturing biologics and advanced therapies, with industrial partnership as main focus for translating research into manufacturing settings.

Dr Torres welcomes new academic collaborations and enquiries from prospective research students.

Research areas

• Mammalian synthetic biology including designing genetic circuits that confer predictable, controllable behaviour on mammalian cells.
• Metabolic and secretory engineering for reprogramming cellular metabolism and the secretory pathway to improve the production of complex biologics in industrial cell lines.
• Cell engineering for advanced therapies including stem cells for enhancing their immunomodulatory function and therapeutic output.
• Biomanufacturing of cell and gene therapies for improving the production of the cells and viral vectors used in advanced therapeutic products.

Collaboration and supervision

Dr Torres actively seeks new academic collaborations, both within his field and across disciplines, and is particularly interested in working with researchers in immunology, disease biology, clinical translation, bioprocessing, and computational modelling. He also welcomes applications from prospective PhD and MPhil students with backgrounds in engineering, biotechnology, or the molecular life sciences. Enquiries, accompanied by a curriculum vitae and a brief statement of research interests, are warmly received.

​Dr Tosolini is a cell biologist with a focus at the intersection of axonal transport, neurotrophic factors, motor neurons and skeletal muscle, in the context of motor neuron disease (MND)/amyotrophic lateral sclerosis (ALS). His research to date has focused on utilising the connectivity between skeletal muscle and motor neurons for the enhanced delivery of therapeutic agents to the spinal cord (e.g., viral-mediated gene therapy). Building upon these foundations, his postdoctoral training focused on defining the axonal transport dynamics in a number of different experimental conditions, including stimulation with different neurotrophic factors (e.g., BDNF, GDNF), α motor neuron subtypes (i.e., fast motor neurons vs slow motor neurons), and alterations to such factors in MND/ALS pathology.

Dr Tosolini has joined the laboratories of A/Prof. Shyuan Ngo (AIBN) and Dr. Derek Steyn (SBMS) to undertake a novel project looking at assessing a novel therapeutic compound in mouse models of ALS, and in as well as in ALS patient-derived muscle cultures. This project is in collaboration with Dr. Giovanni Nardo at Laboratory of Molecular Neurobiology, Department of Neuroscience, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Milan, Italy.

​Dr Tosolini completed his PhD in 2015 in the discipline of Anatomy at the School of Medical Sciences, University of New South Wales (UNSW). His PhD project focused on characterising the connectivity between various skeletal muscles and their innervating motor neuron pools, to optimally deliver agents (e.g., retrograde tracers, virus) to the spinal cord motor neurons via retrograde axonal transport. For the work produced in his PhD, Dr Tosolini was awarded a place on the Faculty of Medicine's Dean's List.

In 2016, Dr Tosolini joined the Schiavo Laboratory at University College London (UCL), UK as a Post-Doctoral Research Associate to undertake a project focused on: 1) understanding factors influencing axonal transport dynamics in distinct in vitro and in vivo models of motor neuron disease (MND)/amyotrophic lateral sclerosis (ALS), and 2) revealing the signalling elements governing neuronal trans-synaptic transfer.

In 2020, Dr Tosolini was awarded a Junior Non-Clinical Post-Doctoral Fellowship by the Motor Neuron Disease Association, UK to expand his work on evaluating axonal transport dynamics in mouse models of motor neuron disease (MND) as well as in diverse human induced pluripotent stem cell (hiPSC)-derived motor neurons. This project is a direct continuation of my post-doctoral training in the Schiavo laboratory, and included a novel collaboration with Prof. Rickie Patani (Francis Crick Institute, London, UK), to evaluate axonal transport dynamics of diverse organelles in mouse and human models of MND/ALS.

Associate Professor Kelvin Tuong is an NHMRC Emerging Leadership Fellow and Deputy Director and group Leader of the Ian Frazer Centre for Children’s Immunotherapy Research (IFCCIR), Child Health Research Centre. He is interested in single-cell analysis of immune cells and harnessing adaptive immune receptors for understanding immune cell development and function in health and in cancer.

A/Prof Tuong was born and raised in Singapore and moved to Brisbane, Australia, after completing national service in Singapore and obtaining a Diploma in Biomedical Laboratory Technology (Ngee Ann Polytechnic).

A/Prof Tuong was originally trained as a molecular cell biologist and gradually transitioned into bioinformatics during his post-doctoral training. He has been very prolific for an early career researcher, having published >70 articles since 2013, with nearly a third of them as first/co-first or last author and has a stellar track record of pushing out highly collaborative work in prestigious journals including Nature, Cell, Science, Nature Medicine, Nature Biotechnology J Exp Med etc. He has the rare combination of having excellent laboratory and bioinformatics skill sets which provide him a strong command of both fundamental immunology and computational approaches.

A/Prof Tuong completed his undergraduate Bachelor's degree in Biomedical science with Class I Honours, followed by his PhD in macrophage cell biology and endocrinology at UQ (Prof Jenny Stow lab and Emiritus Prof George Muscat lab, IMB, UQ). He then went on to a post-doc position with Emiritus Prof Ian Frazer (co-inventor of the Gardasil cervical cancer vaccine, UQ Frazer Institute, Translational Research Institute) where he worked on HPV immunology, cervical cancer and skin cancer. In his time in the Frazer lab, he developed an interest in bioinformatics analyses as a means to tackle and understanding immunology problems in health and disease. He then moved to the UK and joined Prof Menna Clatworthy's lab at the University of Cambridge and Prof Sarah Teichmann's lab at the Wellcome Trust Sanger Institute. He has focused his interests on single-cell analyses of tissue immune cells, including T and B cells and their specific receptors (TCR/BCR). He has developed bespoke bioinformatics software, including one tailored for single-cell B Cell Receptor sequencing analysis, Dandelion, which he used in one of the largest combined single-cell transcriptomic, surface proteomic and TCR/BCR sequencing dataset in the world, published in Nature Medicine, and more recently in Nature Biotechnology where we introduced a TCR-based pseudotime trajectory analysis method.

A/Prof Tuong is now leading the Computational Immunology group at the IFCCIR and his lab is focused on investigating how pediatric immunity is perturbed during cancer at the cellular level and how this information can be used for creating novel warning systems for children with cancer. For potential students/post-docs/trainees interested in joining the team, please contact A/Prof Tuong at z.tuong@uq.edu.au.

Mark is a Professor of food microbiology and serves as the current Discipline Head of Food Science & Technology in the School of Agriculture and Food Sustainability. Between 2019 and 2025 he held the position of Deputy Head of School where he played (and continues to play) a significant role in staff mentoring and the preparation of academic staff for probation and promotion. Mark is also currently a Deputy Lead of the Innovative Ingredients program at the Food and Beverage Accelerator (FaBA), funded by the Australian Trailblazer university program scheme. He leads a research team focused on food safety, quality, and fermentation. After completing his PhD at Queensland University of Technology (QUT) he underwent postdoctoral training at Cornell University, USA (1999-2000), and at the CRC for Diagnostic Technologies, QUT (2000-01). He subsequently supported his position through a Dairy Australia Fellowship (2001-03) and an NHMRC New Investigator Grant (2004-06). In 2007, he joined UQ as an academic specialising in food microbiology.

Mark's research is currently funded by Hort Innovation, and he has received past funding from ARC Discovery, ARC Linkage, ARC Industrial Transformation Research Hub and ARC Industry Transformation Training Centre schemes. He has also been supported by Agrifutures Australia, Dairy Innovation Australia Ltd (DIAL), and the Geoffrey Gardiner Dairy Foundation (GGDF). His research primarily focuses on foodborne pathogen source tracking using WGS, lactic acid bacteria applications, plant-based dairy alternative fermentations, beer fermentation microbiology, precision fermentation and biocontrol food applications targeting pathogens like Campylobacter and Listeria monocytogenes. He has successfully supervised 25 PhD and MPhil students to completion.

Mark was the Director of the Master of Food Science & Technology program from 2008-2018. He contributes to teaching in food microbiology, food safety, and food biotechnology subjects at UQ. He is a Fellow of both the Australian Society for Microbiology (FASM) and the Australian Institute of Food Science and Technology (FAIFST), and serves on the editorial boards the Journal of Food Protection and Fermented Foods. He was the recipient of the 2017 Keith Farrer Award of Merit and the 2023 President's Award from the Australian Institute of Food Science and Technology (AIFST) for service to the food industry and the Institute. Additionally, Mark currently holds the position of President of the Australian Association for Food Protection (AAFP), an affiliate of the International Association for Food Protection (IAFP). He is also currently co-Convenor of the AIFST Education Special Interest Group, coordinating national activities to promote and support excellence in food science and technology education across tertiary and vocational education and training sectors.

Dr Turni leads a national and international reference laboratory for respiratory bacterial pathogens where identification, serotyping, genotyping, sequencing and antimicrobial sensitivity testing is performed. Her team works with the poultry, pig and cattle industries, as well as major veterinary pharmaceutical companies around the world. The group performs vaccine efficacy trials, provides advice on vaccine strain selection, performs antimicrobial sensitivity testing and evaluates candidate novel antimicrobial agents. Essentially, the services provided by the group underpins the entire Australian prevention and control programs for the major bacterial respiratory diseases of pigs, poultry and cattle.

Her research has extended beyond vaccines and antibiotic sensitivity to determining optimal sample sites for collecting pathogens, understanding the association of different pathogens with disease, development of animal infection models, classification of bacteria and epidemiology of pathogens. Conny supervises PhD students with diverse projects such as antimicrobial sensitivity studies, risk factors and profiling of pathogenic Escherichia coli associated with avian collibacillosis, alternatives to antibiotics, development of on farm test for a virus and study of epidemiology of a new species of bacteria. She works in collaboration with a team of epidemiologist, veterinarian and virologist on projects in Australia and overseas.

Dr. Susannah Tye joined the Queensland Brain Institute in 2017 and has established a research program within the Asia Pacific Centre for Neuromodulation (QLD, Australia). Before returning to Australia, Dr. Tye directed the Translational Neuroscience Laboratory at the Mayo Clinic (2012-2017). While there she led efforts to develop brain stimulation devices (for rodents and humans) that can quantify neural activity and neurotransmitter dynamics in the living brain. This body of work now forms the basis of the neuropsychiatric arm of the Mayo Clinic’s Deep Brain Stimulation Consortium. Her specific research expertise are in utilising voltammetric (electrochemical) recording techniques to monitor rapid, synaptic neurotransmission in the living brain.

Dr. Tye has over ten years of experience studying neuromodulation in preclinical rodent models and human patients. Her long-term goal is to bridge preclinical and clinical studies to maximise translational impact, specifically in terms of improving patient outcomes for those with severe refractory psychiatric illness. Towards this end, she maintains many international collaborations with both clinical and basic science researchers. Dr. Tye also has a longstanding interest in mentoring young scientists to help them expand their skills in preclinical and basic science research and achieve a successful research career.

Professor Bruno van Swinderen received his PhD in Evolutionary and Population Biology in 1998 from Washington University in St. Louis, Missouri. His graduate work was on general anesthesia in a Caenorhabditis elegans model, applying both quantitative genetics and molecular genetic approaches. For his postdoc at The Neurosciences Institute (NSI) in San Diego, California (1999-2003), he switched to Drosophila melanogaster to develop methods of studying perception in the fruit-fly model. He ran a lab at NSI from 2003 to late 2007.

Professor van Swinderen established a new laboratory at the Queensland Brain Institute in February 2008.

Bruno van Swinderen's group use Drosophila as a genetic model system to study mechanisms of perception in the brain and are interested in three phenomena: selective attention, sleep, and general anesthesia. Their focus is on visual perception and how it is affected by these different arousal states. Their current effort is in understanding how sleep regulates selective attention and predictive processing. Toward this goal, they use various novel visual paradigms in a Drosophila molecular genetics context. The lab is also focussed on understanding presynaptic mechamisms of general anaesthesia, with a view to uncovering new strategies to improve recovery from this common medical procedure.

Visscher joined the University of Queensland in 2011, where he is Professor of Quantitative Genetics. He is a Laureate Fellow of the Australian Research Council. Visscher was elected a Fellow of the Australian Academy of Science in 2010, a Fellow of the Royal Society (London) in 2018 and a Foreign Member of the Royal Netherlands Academy of Arts and Sciences in 2018.

Visscher’s research is about genetic variation for complex traits (including quantitative traits and disease) in populations, with the broad aim to understand and quantify the causes and consequences of human trait variation.

Prof Peter Visscher, Prof Naomi Wray and Prof Jian Yang together comprise the Executive Team of the Program in Complex Trait Genomics (PCTG). PCTG comprises a critical mass of more than 30 post-doctoral researchers plus research assistants and students, all supported by external grant funding. Their skills lie in the ability to develop and apply statistical methods within the framework of quantitative, population and statistical genetics and to use theory to understand and predict results from data analyses. They play leading roles in the international research consortia. The focus of current research activities is in the detection and fine-mapping of loci underlying complex traits (including common disease), based upon theoretical studies and applications of methods to large datasets, in population genetics studies using theoretical approaches and high-density genetic marker data, and in systems genomics studies.

Dr T. Thang Vo-Doan is a Lecturer of the School of Mechanical and Mining Engineering at the University of Queensland. He was a postdoctoral researcher at the Institute of Biology I, University of Freiburg, Germany (2019-2023). He was also a Research Fellow at Nanyang Technological University (NTU), Singapore (2016-2018). He was awarded his PhD in Mechanical Engineering from the School of Mechanical & Aerospace Engineering, NTU in 2016. He received his M.Eng. degree in Manufacturing Engineering and B.Eng. degree in Mechanical Engineering from Ho Chi Minh City University of Technology, Vietnam in 2010 and 2008 respectively. He was awarded the prestigious Human Frontier Science Program Cross-disciplinary Fellowship (2019-2022).

He directs the UQ Biorobotics lab after joining in the University of Queensland. Current research activities of the lab focus on insect-machine hybrid robots, bio-inspired robotics, insect structures and functions, biomechanics, fast lock-on tracking, and brain imaging in untethered insects.

Overview

Professor Waldemar Vollmer is a microbiologist working on the structure and biogenesis of the bacterial cell wall in various model bacteria and a range of pathogenic and environmental bacteria. He is particularly interested in how bacteria enlarge their cell wall when they grow and divide, and how antibiotics inhibit cell wall synthesis to kill bacteria. Antimicrobial resistance (AMR) is a global problem that is predicted to claim 10 million lives annually by the year 2050 if no new antibiotics are developed. Currently the pipeline of antibiotic development is almost empty and mostly limited to slightly modified versions to existing antibiotics. Professor Vollmer addresses the problem of AMR by generating tailored assays for the development of novel antibiotics that target AMR bacteria.

Collaborations: Professor Vollmer collaborates world-wide with more than 50 researchers at top national and international institutions on cell wall topics in over 30 different bacteria. These topics include: structure and composition of the cell wall and its role in maintaining cell morphology; molecular mechanisms of cell envelope biogenesis; role of new cell wall modifying enzymes in the interaction of pathogenic bacteria with components of the immune system; mechanisms of antibiotic resistance and targeting of cell wall biogenesis by new antibiotics.

Funding and Publications: Professor Vollmer has been awarded more than $15 million funding from research councils and charities in Germany, UK, Europe and USA. He has published more than 200 articles in international journals and has been recognised as a Highly Cited Researcher in Microbiology.

Honours and Awards: Professor Vollmer has been elected to Fellow of the American Academy of Microbiology (2014) and European Academy of Microbiology (2018). He received the annual Academic Distinction Awards from the Vice Chancellor of Newcastle University (2014), has been awarded a Distinguished Scientist Visiting Scholarships at Ben-Gurion University of the Negev (Israel, 2012) and a Visiting Professorship at the University of Cagliari (Italy, 2015), and won a Wellcome Trust Senior Investigator Award (2014). He has co-organised the 2018 Gordon Conference (GRC) "Bacterial Cell Surfaces" (Mt Snow, USA) and the 2016 EMBO Workshop "Bacterial Cell Division: Orchestrating the Ring Cycle" (Prague, Czech Republic).

Short Biography: Prof Waldemar Vollmer has studied chemistry at the University of Applied Sciences in Reutlingen (Germany) and University of Basel (Switzerland). In 1998 he obtained a PhD degree (Dr.rer.nat.) from the University of Tübingen (Germany) for his work on cell wall synthesis in the model bacterium Escherichia coli undertaken at the Max Planck Institute for Developmental Biology. During his postdoctoral studies at the Rockefeller University (New York, USA) he discovered novel cell wall enzymes that are crucial for the virulence of the pathogenic bacterium Streptococcus pneumoiae. In 2003 he was appointed Assistant Professor at the University of Tübingen and moved 2007 to the Centre for Bacterial Cell Biology at Newcastle University (UK), where he worked as Professor of Bacterial Biochemistry on various bacterial cell wall topics in a range of different bacteria. Since April 2023 he is Professorial Research Fellow and Group Leader at the Centre for Superbug Solutions, Institute for Molecular Bioscience (IMB) at the University of Queensland.

Dr Adam Walker received his BSc(Hons) in Biochemistry from the University of Tasmania, and PhD in Neuroscience from the Florey Institute of Neuroscience and Mental Health at the University of Melbourne, focused on understanding the molecular mechanisms of motor neuron disease (MND). He undertook a postdoctoral fellowship with Professor Virginia Lee at the Center for Neurodegenerative Disease Research, University of Pennsylvania (2011-2015), developing new transgenic TDP-43 mouse models of disease. Dr Walker was previously an NHMRC CJ Martin Overseas Biomedical Research Fellow and was awarded an NHMRC RD Wright Career Development Fellowship (2018-2022), to continue his research on neurodegenerative diseases.

He was Group Leader in the Clem Jones Centre for Ageing Dementia Research at the Queensland Brain Institute 2018-2025, and is now Honorary Professor.