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2014

Journal Article

Design and development of exome capture sequencing for the domestic pig (Sus scrofa)

Robert, Christelle, Fuentes-Utrilla, Pablo, Troup, Karen, Loecherbach, Julia, Turner, Frances, Talbot, Richard, Archibald, Alan L., Mileham, Alan, Deeb, Nader, Hume, David A. and Watson, Mick (2014). Design and development of exome capture sequencing for the domestic pig (Sus scrofa). BMC Genomics, 15 (1) 550. doi: 10.1186/1471-2164-15-550

Design and development of exome capture sequencing for the domestic pig (Sus scrofa)

2014

Journal Article

Transcription and enhancer profiling in human monocyte subsets

Schmidl, Christian, Renner, Kathrin, Peter, Katrin, Eder, Ruediger, Lassmann, Timo, Balwierz, Piotr J., Itoh, Masayohshi, Nagao-Sato, Sayaka, Kawaji, Hideya, Carninci, Piero, Suzuki, Harukazu, Hayashizaki, Yoshihide, Andreesen, Reinhard, Hume, David A., Hoffmann, Petra, Forrest, Alistair R. R., Kreutz, Marina P., Edinger, Matthias, Rehli, Michael, for the FANTOM consortium, Beckhouse, Anthony, Wells, Christine, Vijayan, Dipti, Mason, Elizabeth, Wolvetang, Ernst, Hitchens, Kelly, Le Cao, Kim-Anh, Nielsen, Lars, Fearnley, Liam and Kenna, Tony (2014). Transcription and enhancer profiling in human monocyte subsets. Blood, 123 (17), e90-e99. doi: 10.1182/blood-2013-02-484188

Transcription and enhancer profiling in human monocyte subsets

2014

Journal Article

An atlas of active enhancers across human cell types and tissues

Andersson, Robin, Gebhard, Claudia, Miguel-Escalada, Irene, Hoof, Ilka, Bornholdt, Jette, Boyd, Mette, Chen, Yun, Zhao, Xiaobei, Schmidl, Christian, Suzuki, Takahiro, Ntini, Evgenia, Arner, Erik, Valen, Eivind, Li, Kang, Schwarzfischer, Lucia, Glatz, Dagmar, Raithel, Johanna, Lilje, Berit, Rapin, Nicolas, Bagger, Frederik Otzen, Jørgensen, Mette, Andersen, Peter Refsing, Bertin, Nicolas, Rackham, Owen, Burroughs, A. Maxwell, Baillie, J. Kenneth, Ishizu, Yuri, Shimizu, Yuri, Furuhata, Erina ... Sandelin, Albin (2014). An atlas of active enhancers across human cell types and tissues. Nature, 507 (7493), 455-461. doi: 10.1038/nature12787

An atlas of active enhancers across human cell types and tissues

2014

Journal Article

Transcriptional switching in macrophages associated with the peritoneal foreign body response

Mooney, Jane E., Summers, Kim M., Gongora, Milena, Grimmond, Sean M., Campbell, Julie H., Hume, David A. and Rolfe, Barbara E. (2014). Transcriptional switching in macrophages associated with the peritoneal foreign body response. Immunology and Cell Biology, 92 (6), 518-526. doi: 10.1038/icb.2014.19

Transcriptional switching in macrophages associated with the peritoneal foreign body response

2014

Journal Article

Network analysis reveals distinct clinical syndromes underlying acute mountain sickness

Hall, David P., MacCormick, Ian J. C., Phythian-Adams, Alex T., Rzechorzek, Nina M., Hope-Jones, David, Cosens, Sorrel, Jackson, Stewart, Bates, Matthew G. D., Collier, David J., Hume, David A., Freeman, Thomas, Thompson, A. A. Roger and Baillie, John Kenneth (2014). Network analysis reveals distinct clinical syndromes underlying acute mountain sickness. PLoS ONE, 9 (1) e81229, e81229. doi: 10.1371/journal.pone.0081229

Network analysis reveals distinct clinical syndromes underlying acute mountain sickness

2014

Journal Article

Lentiviral vectors containing mouse Csf1r control elements direct macrophage-restricted expression in multiple species of birds and mammals

Pridans, Clare, Lillico, Simon, Whitelaw, Bruce and Hume, David A. (2014). Lentiviral vectors containing mouse Csf1r control elements direct macrophage-restricted expression in multiple species of birds and mammals. Molecular Therapy - Methods and Clinical Development, 1 14010, 14010. doi: 10.1038/mtm.2014.10

Lentiviral vectors containing mouse Csf1r control elements direct macrophage-restricted expression in multiple species of birds and mammals

2014

Journal Article

Visualisation of chicken macrophages using transgenic reporter genes: insights into the development of the avian macrophage lineage

Balic, Adam, Garcia-Morales, Carla, Vervelde, Lonneke, Gilhooley, Hazel, Sherman, Adrian, Garceau, Valerie, Gutowska, Maria W., Burt, David W., Kaiser, Pete, Hume, David A. and Sang, Helen M. (2014). Visualisation of chicken macrophages using transgenic reporter genes: insights into the development of the avian macrophage lineage. Development, 141 (16), 3255-3265. doi: 10.1242/dev.105593

Visualisation of chicken macrophages using transgenic reporter genes: insights into the development of the avian macrophage lineage

2014

Journal Article

Homeostasis in the mononuclear phagocyte system

Jenkins, Stephen J. and Hume, David A. (2014). Homeostasis in the mononuclear phagocyte system. Trends in Immunology, 35 (8), 358-367. doi: 10.1016/j.it.2014.06.006

Homeostasis in the mononuclear phagocyte system

2014

Journal Article

A promoter-level mammalian expression atlas

Forest, Alistair R. R., Kawaji, Hideya, Rehli, Michael, Baillie, J. Kenneth, De Hoon, Michael J. L., Haberle, Vanja, Lassmann, Timo, Kulakovskiy, Ivan V., Lizio, Marina, Itoh, Masayoshi, Andersson, Robin, Mungall, Christopher J., Meehan, Terrence F., Schmeier, Sebastian, Bertin, Nicholas, Jorgensen, Mette, Dimont, Emmanuel, Arner, Erik, Schmidl, Christian, Schaefer, Ulf, Medvedeva, Yulia A., Plessy, Charles, Vitezic, Morana, Severin, Jessica, Semple, Colin A., Ishizu, Yuri, Young, Robert S., Francescatto, Margherita, Altschuler, Intikhab ... Hayashizaki, Yoshihide (2014). A promoter-level mammalian expression atlas. Nature, 507 (7493), 462-470. doi: 10.1038/nature13182

A promoter-level mammalian expression atlas

2013

Journal Article

CSF1R mutations in hereditary diffuse leukoencephalopathy with spheroids are loss of function

Pridans, Clare, Sauter, Kristin A., Baer, Kristin, Kissel, Holger and Hume, David A. (2013). CSF1R mutations in hereditary diffuse leukoencephalopathy with spheroids are loss of function. Scientific Reports, 3 (1) 3013. doi: 10.1038/srep03013

CSF1R mutations in hereditary diffuse leukoencephalopathy with spheroids are loss of function

2013

Journal Article

IL-4 directly signals tissue-resident macrophages to proliferate beyond homeostatic levels controlled by CSF-1

Jenkins, Stephen J., Ruckerl, Dominik, Thomas, Graham D., Hewitson, James P., Duncan, Sheelagh, Brombacher, Frank, Maizels, Rick M., Hume, David A. and Allen, Judith E. (2013). IL-4 directly signals tissue-resident macrophages to proliferate beyond homeostatic levels controlled by CSF-1. Journal of Experimental Medicine, 210 (11), 2477-2491. doi: 10.1084/jem.20121999

IL-4 directly signals tissue-resident macrophages to proliferate beyond homeostatic levels controlled by CSF-1

2013

Journal Article

The equine alveolar macrophage: functional and phenotypic comparisons with peritoneal macrophages

Karagianni, Anna E., Kapetanovic, Ronan, McGorum, Bruce C., Hume, David A. and Pirie, Scott R. (2013). The equine alveolar macrophage: functional and phenotypic comparisons with peritoneal macrophages. Veterinary Immunology And Immunopathology, 155 (4), 219-228. doi: 10.1016/j.vetimm.2013.07.003

The equine alveolar macrophage: functional and phenotypic comparisons with peritoneal macrophages

2013

Journal Article

An expression atlas of human primary cells: inference of gene function from coexpression networks

Mabbott, Neil A., Baillie, J. K., Brown, Helen, Freeman, Tom C. and Hume, David A. (2013). An expression atlas of human primary cells: inference of gene function from coexpression networks. BMC Genomics, 14 (1) 632. doi: 10.1186/1471-2164-14-632

An expression atlas of human primary cells: inference of gene function from coexpression networks

2013

Journal Article

CX3CR1 reduces Ly6Chigh-monocyte motility within and release from the bone marrow after chemotherapy in mice

Jacquelin, Sébastien, Licata, Fabrice, Dorgham, Karim, Hermand, Patricia, Poupel, Lucie, Guyon, Elodie, Deterre, Philippe, Hume, David A., Combadière, Christophe and Boissonnas, Alexandre (2013). CX3CR1 reduces Ly6Chigh-monocyte motility within and release from the bone marrow after chemotherapy in mice. Blood, 122 (5), 674-683. doi: 10.1182/blood-2013-01-480749

CX3CR1 reduces Ly6Chigh-monocyte motility within and release from the bone marrow after chemotherapy in mice

2013

Journal Article

The impact of breed and tissue compartment on the response of pig macrophages to lipopolysaccharide

Kapetanovic, Ronan, Fairbairn, Lynsey, Downing, Alison, Beraldi, Dario, Sester, David P., Freeman, Tom C., Tuggle, Christopher K., Archibald, Alan L. and Hume, David A. (2013). The impact of breed and tissue compartment on the response of pig macrophages to lipopolysaccharide. Bmc Genomics, 14 (1) 581. doi: 10.1186/1471-2164-14-581

The impact of breed and tissue compartment on the response of pig macrophages to lipopolysaccharide

2013

Journal Article

Embedding universal covers of graph manifolds in products of trees

Hume, David and Sisto, Alessandro (2013). Embedding universal covers of graph manifolds in products of trees. Proceedings of the American Mathematical Society, 141 (10), 3337-3340. doi: 10.1090/S0002-9939-2013-11669-2

Embedding universal covers of graph manifolds in products of trees

2013

Journal Article

Coexpression analysis of large cancer datasets provides insight into the cellular phenotypes of the tumour microenvironment

Doig, Tamasin N., Hume, David A., Theocharidis, Thanasis, Goodlad, John R., Gregory, Christopher D. and Freeman, Tom C. (2013). Coexpression analysis of large cancer datasets provides insight into the cellular phenotypes of the tumour microenvironment. BMC Genomics, 14 (1) 469. doi: 10.1186/1471-2164-14-469

Coexpression analysis of large cancer datasets provides insight into the cellular phenotypes of the tumour microenvironment

2013

Journal Article

Comparative analysis of monocyte subsets in the pig

Fairbairn, Lynsey, Kapetanovic, Ronan, Beraldi, Dario, Sester, David P., Tuggle, Chris K., Archibald, Alan L. and Hume, David A. (2013). Comparative analysis of monocyte subsets in the pig. Journal of Immunology, 190 (12), 6389-6396. doi: 10.4049/jimmunol.1300365

Comparative analysis of monocyte subsets in the pig

2013

Journal Article

Histone deacetylase 7 promotes Toll-like Receptor 4-dependent pro-inflammatory gene expression in macrophages

Shakespear, Melanie R., Hohenhaus, Daniel M., Kelly, Greg M., Kamal, Nabilah A., Gupta, Praveer, Labzin, Larisa I., Schroder, Kate, Garceau, Valerie, Barbero, Sheila, Iyer, Abishek, Hume, David A., Reid, Robert C., Irvine, Katharine M., Fairlie, David P. and Sweet, Matthew J. (2013). Histone deacetylase 7 promotes Toll-like Receptor 4-dependent pro-inflammatory gene expression in macrophages. Journal of Biological Chemistry, 288 (35), 25362-25374. doi: 10.1074/jbc.M113.496281

Histone deacetylase 7 promotes Toll-like Receptor 4-dependent pro-inflammatory gene expression in macrophages

2013

Journal Article

Regulated expression of PTPRJ/CD148 and an antisense long noncoding RNA in macrophages by proinflammatory stimuli

Dave, Richa K., Dinger, Marcel E., Andrew, Megan, Askarian-Amiri, Marjan, Hume, David A. and Kellie, Stuart (2013). Regulated expression of PTPRJ/CD148 and an antisense long noncoding RNA in macrophages by proinflammatory stimuli. PLoS One, 8 (6) e68306, e68306.1-e68306.13. doi: 10.1371/journal.pone.0068306

Regulated expression of PTPRJ/CD148 and an antisense long noncoding RNA in macrophages by proinflammatory stimuli