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2015 Journal Article Transcriptional dynamics reveal critical roles for non-coding RNAs in the immediate-early responseAitken, Stuart, Magi, Shigeyuki, Alhendi, Ahmad M. N., Itoh, Masayoshi, Kawaji, Hideya, Lassmann, Timo, Daub, Carsten O., Arner, Erik, Carninci, Piero, Forrest, Alistair R. R., Hayashizaki, Yoshihide, Khachigian, Levon M., Okada-Hatakeyama, Mariko, Semple, Colin A., FANTOM Consortium, Forrest, Alistair R. R., Sandelin, Albin, Daub, Carsten O., Wells, Christine, Hume, David A., Arner, Erik, Kawaji, Hideya, Summers, Kim M., Vitting-Seerup, Kristoffer, Carninci, Piero, Andersson, Robin, Hayashizaki, Yoshihide and Yumoto, Noriko (2015). Transcriptional dynamics reveal critical roles for non-coding RNAs in the immediate-early response. PLoS Computational Biology, 11 (4) e1004217, e1004217. doi: 10.1371/journal.pcbi.1004217 |
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2015 Journal Article Transcribed enhancers lead waves of coordinated transcription in transitioning mammalian cellsArner, Erik, Daub, Carsten O., Vitting-Seerup, Kristoffer, Andersson, Robin, Lilje, Berit, Drabløs, Finn, Lennartsson, Andreas, Rönnerblad, Michelle, Hrydziuszko, Olga, Vitezic, Morana, Freeman, Tom C., Alhendi, Ahmad M. N., Arner, Peter, Axton, Richard, Baillie, J. Kenneth, Beckhouse, Anthony, Bodega, Beatrice, Briggs, James, Brombacher, Frank, Davis, Margaret, Detmar, Michael, Ehrlund, Anna, Endoh, Mitsuhiro, Eslami, Afsaneh, Fagiolini, Michela, Fairbairn, Lynsey, Faulkner, Geoffrey J., Ferrai, Carmelo, Fisher, Malcolm E. ... Hayashizaki, Yoshihide (2015). Transcribed enhancers lead waves of coordinated transcription in transitioning mammalian cells. Science, 347 (6225), 1010-1014. doi: 10.1126/science.1259418 |
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2015 Journal Article Technical advance: Transcription factor, promoter, and enhancer utilization in human myeloid cellsJoshi, Anagha, Pooley, Christopher, Freeman, Tom C., Lennartsson, Andreas, Babina, Magda, Schmidl, Christian, Geijtenbeek, Teunis, Michoel, Tom, Severin, Jessica, Itoh, Masayoshi, Lassmann, Timo, Kawaji, Hideya, Hayashizaki, Yoshihide, Carninci, Piero, Forrest, Alistair R. R., Rehli, Michael and Hume, David A. (2015). Technical advance: Transcription factor, promoter, and enhancer utilization in human myeloid cells. Journal of Leukocyte Biology, 97 (5), 985-995. doi: 10.1189/jlb.6TA1014-477RR |
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2015 Journal Article Oncogenic properties of apoptotic tumor cells in aggressive B cell lymphomaFord, Catriona A., Petrova, Sofia, Pound, John D., Voss, Jorine J.L.P., Melville, Lynsey, Paterson, Margaret, Farnworth, Sarah L., Gallimore, Awen M., Cuff, Simone, Wheadon, Helen, Dobbin, Edwina, Ogden, Carol Anne, Dumitriu, Ingrid E., Dunbar, Donald R., Murray, Paul G., Ruckerl, Dominik, Allen, Judith E., Hume, David A., Van Rooijen, Nico, Goodlad, John R., Freeman, Tom C. and Gregory, Christopher D. (2015). Oncogenic properties of apoptotic tumor cells in aggressive B cell lymphoma. Current Biology, 25 (5), 577-588. doi: 10.1016/j.cub.2014.12.059 |
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2015 Journal Article A transcriptional perspective on human macrophage biologySchultze, Joachim L., Freeman, Tom, Hume, David A. and Latz, Eicke (2015). A transcriptional perspective on human macrophage biology. Seminars in Immunology, 27 (1), 44-50. doi: 10.1016/j.smim.2015.02.001 |
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2015 Journal Article The development and maintenance of the mononuclear phagocyte system of the chick is controlled by signals from the macrophage colony-stimulating factor receptorGarceau, Valerie, Balic, Adam, Garcia-Morales, Carla, Sauter, Kristin A., McGrew, Mike J., Smith, Jacqueline, Vervelde, Lonneke, Sherman, Adrian, Fuller, Troy E., Oliphant, Theodore, Shelley, John A., Tiwari, Raksha, Wilson, Thomas L., Chintoan-Uta, Cosmin, Burt, Dave W., Stevens, Mark P., Sang, Helen M. and Hume, David A. (2015). The development and maintenance of the mononuclear phagocyte system of the chick is controlled by signals from the macrophage colony-stimulating factor receptor. BMC Biology, 13 (1) 12, 12.1-12.17. doi: 10.1186/s12915-015-0121-9 |
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2015 Conference Publication Autologous Haematopotetic Stem Cell Transplantation Requires Recipient Bm MacrophagesKaur, Simranpreet, Raggatt, Liza J., Jacobsen, Rebecca, Millard, Susan, Barbier, Valerie, Nowlan, Bianca, Winkler, Ingrid G., MacDonald, Kelli P., Perkins, Andrew C., Hume, David A., Levesque, Jean P. and Pettit, Allison R. (2015). Autologous Haematopotetic Stem Cell Transplantation Requires Recipient Bm Macrophages. 44th Annual Scientific Meeting of the International-Society-for-Experimental-Hematology (ISEH), Kyoto, Japan, 17-19 September 2015. Philadelphia, PA, United States: Elsevier. doi: 10.1016/j.exphem.2015.06.157 |
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2015 Journal Article Orthogonal forms of Kac-moody groups are acylindrically hyperbolicCaprace, Pierre-Emmanuel and Hume, David (2015). Orthogonal forms of Kac-moody groups are acylindrically hyperbolic. Annales de l'Institut Fourier, 65 (6), 2613-2640. doi: 10.5802/aif.2998 |
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2015 Journal Article Exome sequencing: current and future perspectivesWarr, Amanda, Robert, Christelle, Hume, David, Archibald, Alan, Deeb, Nader and Watson, Mick (2015). Exome sequencing: current and future perspectives. G3: Genes, Genomes, Genetics, 5 (8), 1543-1550. doi: 10.1534/g3.115.018564 |
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2015 Journal Article 'Recognised veterinary practice' in the context of clinical field trialsNanjiani, Ian, Hume, David, Fitzpatrick, Julie and Murray, John (2015). 'Recognised veterinary practice' in the context of clinical field trials. Veterinary Record, 176 (21), 552-552. doi: 10.1136/vr.h2718 |
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2015 Journal Article Third Report on Chicken Genes and Chromosomes 2015:Schmid, Michael, Smith, Jacqueline, Burt, David W., Aken, Bronwen L., Antin, Parker B., Archibald, Alan L., Ashwell, Chris, Blackshear, Perry J., Boschiero, Clarissa, Brown, C. Titus, Burgess, Shane C., Cheng, Hans H., Chow, William, Coble, Derrick J., Cooksey, Amanda, Crooijmans, Richard P. M. A., Damas, Joana, Davis, Richard V.N., De Koning, Dirk-Jan, Delany, Mary E., Derrien, Thomas, Desta, Takele T., Dunn, Ian C., Dunn, Matthew, Ellegren, Hans, Eöry, Lél, Erb, Ionas, Farré, Marta, Fasold, Mario ... Zhou, Huaijun (2015). Third Report on Chicken Genes and Chromosomes 2015:. Cytogenetic and Genome Research, 145 (2), 78-179. doi: 10.1159/000430927 |
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2015 Journal Article Cell-autonomous sex differences in gene expression in chicken bone marrow-derived macrophagesGarcia-Morales, Carla, Nandi, Sunil, Zhao, Debiao, Sauter, Kristin A., Vervelde, Lonneke, McBride, Derek, Sang, Helen M., Clinton, Mike and Hume, David A. (2015). Cell-autonomous sex differences in gene expression in chicken bone marrow-derived macrophages. Journal of Immunology, 194 (5), 2338-2344. doi: 10.4049/jimmunol.1401982 |
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2015 Journal Article Identification of low-confidence regions in the pig reference genome (Sscrofa10.2)Warr, Amanda, Robert, Christelle, Hume, David, Archibald, Alan L., Deeb, Nader and Watson, Mick (2015). Identification of low-confidence regions in the pig reference genome (Sscrofa10.2). Frontiers in Genetics, 6 (NOV) 338. doi: 10.3389/fgene.2015.00338 |
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2014 Journal Article Characterisation of a novel fc conjugate of macrophage colony-stimulating factorGow, Deborah J, Sauter, Kristin A., Pridans, Clare, Moffat, Lindsey, Sehgal, Anuj, Stutchfield, Ben M., Raza, Sobia, Beard, Philippa M., Tsai, Yi Ting, Bainbridge, Graeme, Boner, Pamela L., Fici, Greg, Garcia-Tapia, David, Martin, Roger A., Oliphant, Theodore, Shelly, John A., Tiwari, Raksha, Wilson, Thomas L., Smith, Lee B., Mabbott, Neil A. and Hume, David A. (2014). Characterisation of a novel fc conjugate of macrophage colony-stimulating factor. Molecular Therapy, 22 (9), 1580-1592. doi: 10.1038/mt.2014.112 |
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2014 Journal Article Development and characterisation of monoclonal antibodies reactive with porcine CSF1R (CD115)Moffat, L., Rothwell, L., Garcia-Morales, C., Sauter, K. A., Kapetanovic, R., Gow, D. J. and Hume, D. A. (2014). Development and characterisation of monoclonal antibodies reactive with porcine CSF1R (CD115). Developmental and Comparative Immunology, 47 (1), 123-128. doi: 10.1016/j.dci.2014.07.001 |
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2014 Journal Article Transcriptomic analysis of mononuclear phagocyte differentiation and activationHume, David A. and Freeman, Tom C. (2014). Transcriptomic analysis of mononuclear phagocyte differentiation and activation. Immunological Reviews, 262 (1), 74-84. doi: 10.1111/imr.12211 |
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2014 Journal Article Production and characterisation of a monoclonal antibody that recognises the chicken CSF1 receptor and confirms that expression is restricted to macrophage-lineage cellsGarcia-Morales, Carla, Rothwell, Lisa, Moffat, Lindsey, Garceau, Valerie, Balic, Adam, Sang, Helen M., Kaiser, Pete and Hume, David A. (2014). Production and characterisation of a monoclonal antibody that recognises the chicken CSF1 receptor and confirms that expression is restricted to macrophage-lineage cells. Developmental and Comparative Immunology, 42 (2), 278-285. doi: 10.1016/j.dci.2013.09.011 |
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2014 Journal Article The MacBlue Binary Transgene (csf1r-gal4VP16/UAS-ECFP) provides a novel marker for visualisation of subsets of monocytes, macrophages and dendritic cells and responsiveness to CSF1 administrationSauter, Kristin A., Pridans, Clare, Sehgal, Anuj, Bain, Calum C., Scott, Charlotte, Moffat, Lindsey, Rojo, Rocío, Stutchfield, Ben M., Davies, Claire L., Donaldson, David S., Renault, Kathleen, McColl, Barry W., Mowat, Alan M., Serrels, Alan, Frame, Margaret C., Mabbott, Neil A. and Hume, David A. (2014). The MacBlue Binary Transgene (csf1r-gal4VP16/UAS-ECFP) provides a novel marker for visualisation of subsets of monocytes, macrophages and dendritic cells and responsiveness to CSF1 administration. PLoS ONE, 9 (8) e105429, 1-12. doi: 10.1371/journal.pone.0105429 |
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2014 Journal Article Pleiotropic effects of extended blockade of CSF1R signaling in adult miceSauter, Kristin A., Pridans, Clare, Sehgal, Anuj, Tsai, Yi Ting, Bradford, Barry M., Raza, Sobia, Moffat, Lindsey, Gow, Deborah J., Beard, Philippa M., Mabbott, Neil A., Smith, Lee B. and Hume, David A. (2014). Pleiotropic effects of extended blockade of CSF1R signaling in adult mice. Journal of Leukocyte Biology, 96 (2), 265-274. doi: 10.1189/jlb.2A0114-006R |
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2014 Journal Article Analysis of the transcriptional networks underpinning the activation of murine macrophages by inflammatory mediatorsRaza, Sobia, Barnett, Mark W., Barnett-Itzhaki, Zohar, Amit, Ido, Hume, David A. and Freeman, Tom C. (2014). Analysis of the transcriptional networks underpinning the activation of murine macrophages by inflammatory mediators. Journal of Leukocyte Biology, 96 (2), 167-183. doi: 10.1189/jlb.6HI0313-169R |
