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2011 Journal Article Somatic retrotransposition alters the genetic landscape of the human brainBaillie, J. Kenneth, Barnett, Mark W., Upton, Kyle R., Gerhardt, Daniel J., Richmond, Todd A., De Sapio, Fioravante, Brennan. Paul M., Rizzu, Patrizia, Smith, Sarah, Fell, Mark, Talbot, Richard T., Gustincich, Stefano, Freeman, Thomas C., Mattick, John S., Hume, David A., Heutink, Peter, Carninci, Piero, Jeddeloh, Jeffrey A. and Faulkner, Geoffrey J. (2011). Somatic retrotransposition alters the genetic landscape of the human brain. Nature, 479 (7374), 534-537. doi: 10.1038/nature10531 |
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2011 Journal Article Colony-stimulating factor-1 promotes kidney growth and repair via alteration of macrophage responsesAlikhan, Maliha A., Jones, Christina V., Williams, Timothy M., Beckhouse, Anthony G., Fletcher , Anne L., Kett, Michelle M., Sakkal, Samy, Samuel, Chrishan S., Ramsay, Robert G., Deane, James A., Wells, Christine A., Little, Melissa H., Hume, David A. and Ricardo, Sharon D. (2011). Colony-stimulating factor-1 promotes kidney growth and repair via alteration of macrophage responses. The American Journal of Pathology, 179 (3), 1243-1256. doi: 10.1016/j.ajpath.2011.05.037 |
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2011 Journal Article Osteal tissue macrophages promote in vivo intramembranous bone healing in a mouse tibial injury modelAlexander, Kylie A., Chang, Ming K., Maylin, Erin R., Kohler, Thomas, Meuller, Ralph, Wu, Andy C., van Rooijen, Nico, Sweet, Matthew J ., Hume, David A., Raggatt, Liza J. and Pettit, Allison R. (2011). Osteal tissue macrophages promote in vivo intramembranous bone healing in a mouse tibial injury model. Journal of Bone And Mineral Research, 26 (7), 1517-1532. doi: 10.1002/jbmr.354 |
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2011 Journal Article The mononuclear phagocyte system of the pig as a model for understanding human innate immunity and diseaseFairbairn, Lynsey, Kapetanovic, Ronan, Sester, David P. and Hume, David A. (2011). The mononuclear phagocyte system of the pig as a model for understanding human innate immunity and disease. Journal of Leukocyte Biology, 89 (6), 855-871. doi: 10.1189/jlb.1110607 |
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2011 Journal Article Macrophage therapy for murine liver fibrosis recruits host effector cells improving fibrosis, regeneration, and functionThomas, James A., Pope, Caroline, Wojtacha, Davina, Robson, Andrew J., Gordon-Walker, Timothy T., Hartland, Stephen, Ramachandran, Prakash, Van Deemter, Marielle, Hume, David A., Iredale, John P. and Forbes, Stuart J. (2011). Macrophage therapy for murine liver fibrosis recruits host effector cells improving fibrosis, regeneration, and function. Hepatology, 53 (6), 2003-2015. doi: 10.1002/hep.24315 |
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2011 Journal Article Applications of myeloid-specific promoters in transgenic mice support in vivo imaging and functional genomics but do not support the concept of distinct macrophage and dendritic cell lineages or roles in immunityHume, David A. (2011). Applications of myeloid-specific promoters in transgenic mice support in vivo imaging and functional genomics but do not support the concept of distinct macrophage and dendritic cell lineages or roles in immunity. Journal of Leukocyte Biology, 89 (4), 525-538. doi: 10.1189/jlb.0810472 |
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2011 Journal Article The immunostimulatory activity of phosphorothioate CpG oligonucleotides is affected by distal sequence changesRoberts, Tara L., Dunn, Jasmyn A., Sweet, Matthew J., Hume, David A. and Stacey, Katryn J. (2011). The immunostimulatory activity of phosphorothioate CpG oligonucleotides is affected by distal sequence changes. Molecular Immunology, 48 (8), 1027-1034. doi: 10.1016/j.molimm.2011.01.011 |
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2011 Journal Article The future of animal production: improving productivity and sustainabilityHume, D. A., Whitelaw, C. B. A. and Archibald, A. L. (2011). The future of animal production: improving productivity and sustainability. Journal of Agricultural Science, 149 (S1), 9-16. doi: 10.1017/S0021859610001188 |
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2011 Journal Article Macrophage activation and differentiation signals regulate Schlafen-4 gene expression: Evidence for Schlafen-4 as a modulator of myelopoiesisVan Zuylen, Wendy J., Garceau, Valerie, Idris, Adi, Schroder, Kate, Irvine, Katharine M., Lattin, Jane E., Ovchinnikov, Dmitry A., Perkins, Andrew C., Cook, Andrew D., Hamilton, John A., Hertzog, Paul J., Stacey, Katryn J., Kellie, Stuart, Hume, David A. and Sweet, Matthew J. (2011). Macrophage activation and differentiation signals regulate Schlafen-4 gene expression: Evidence for Schlafen-4 as a modulator of myelopoiesis. PLoS One, 6 (1) e15723, e15723-1-e15723-13. doi: 10.1371/journal.pone.0015723 |
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2011 Conference Publication Gene targeting of the rat Csf1r locus using homologous recombination in ES cellsUpton, Kyle R., Pridans, Clare, Meek, Stephen, Sutherland, Linda, Whitelaw, Bruce, Burdon, Tom and Hume, David (2011). Gene targeting of the rat Csf1r locus using homologous recombination in ES cells. 10th Transgenic Technology Meeting (TT2011), Florida, United States, 24-26 October 2011. Dordrecht, Netherlands: Springer Netherlands. doi: 10.1007/s11248-011-9540-8 |
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2010 Journal Article An antibody against the colony-stimulating factor 1 receptor (CSF1R) depletes the resident subset of monocytes and tissue and tumor-associated macrophages but does not inhibit inflammationMacDonald, Kelli P. A., Palmer, James S., Cronau, Stephen, Seppanen, Elke Jane, Olver, Stuart, Raffelt, Neil C., Kuns, Rachel, Pettit, Allison R., Clouston, Andrew, Wainwright, Brandon J., Branstetter, Dan, Smith, Jeffrey, Paxton, Raymond J., Cerretti, Douglas Pat, Bonham, Lynn, Hill, Geoffrey R. and Hume, David A. (2010). An antibody against the colony-stimulating factor 1 receptor (CSF1R) depletes the resident subset of monocytes and tissue and tumor-associated macrophages but does not inhibit inflammation. Blood, 116 (19), 3955-3963. doi: 10.1182/blood-2010-02-266296 |
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2010 Journal Article Co-expression of FBN1 with mesenchyme-specific genes in mouse cell lines: implications for phenotypic variability in Marfan syndromeSummers, Kim M., Raza, Sobia, van Nimwegen, Erik, Freeman, Thomas C. and Hume, David A. (2010). Co-expression of FBN1 with mesenchyme-specific genes in mouse cell lines: implications for phenotypic variability in Marfan syndrome. European Journal of Human Genetics, 18 (11), 1209-1215. doi: 10.1038/ejhg.2010.91 |
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2010 Journal Article Meta-analysis of lineage-specific gene expression signatures in mouse leukocyte populationsMabbott, Neil A., Baillie, J. Kenneth, Hume, David A. and Freeman, Tom C. (2010). Meta-analysis of lineage-specific gene expression signatures in mouse leukocyte populations. Immunobiology, 215 (9-10), 724-736. doi: 10.1016/j.imbio.2010.05.012 |
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2010 Journal Article CSF-1, IGF-1, and the control of postnatal growth and developmentGow, Deborah J., Sester, David P. and Hume, David A. (2010). CSF-1, IGF-1, and the control of postnatal growth and development. Journal of Leukocyte Biology, 88 (3), 475-481. doi: 10.1189/jlb.0310158 |
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2010 Journal Article The combination of gene perturbation assay and ChIP-chip reveals functional direct target genes for IRF8 in THP-1 cellsKubosaki, A, Lindgren, G, Tagami, M, Simon, C, Tomaru, Y, Miura, H, Suzuki, T, Arner, E, Forrest, ARR, Irvine, KM, Schroder, K, Hasegawa, Y, Kanamori-Katayama, M, Rehli, M, Hume, DA, Kawai, J, Suzuki, M, Suzuki, H and Hayashizaki, Y (2010). The combination of gene perturbation assay and ChIP-chip reveals functional direct target genes for IRF8 in THP-1 cells. Molecular Immunology, 47 (14), 2295-2302. doi: 10.1016/j.molimm.2010.05.289 |
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2010 Journal Article Differential effects of selective HDAC inhibitors on macrophage inflammatory responses to the Toll-like receptor 4 agonist LPSHalili, Maria A., Andrews, Melanie R., Labzin, Larisa I., Schroder, Kate, Matthias, Gabriele, Cao, Chun, Lovelace, Erica, Reid, Robert C., Le, Giang T., Hume, David A., Irvine, Katharine M., Matthias, Patrick, Fairlie, David P. and Sweet, Matthew J. (2010). Differential effects of selective HDAC inhibitors on macrophage inflammatory responses to the Toll-like receptor 4 agonist LPS. Journal of Leukocyte Biology, 87 (6), 1103-1114. doi: 10.1189/jlb.0509363 |
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2010 Journal Article Functional clustering and lineage markers: insights into cellular differentiation and gene function from large-scale microarray studies of purified primary cell populationsHume, David A., Summers, Kim M., Raza, Sobia, Baillie, J. Kenneth and Freeman, Thomas C. (2010). Functional clustering and lineage markers: insights into cellular differentiation and gene function from large-scale microarray studies of purified primary cell populations. Genomics, 95 (6), 328-338. doi: 10.1016/j.ygeno.2010.03.002 |
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2010 Journal Article Unravelling mononuclear phagocyte heterogeneityGeissmann, Frederic, Gordon, Siamon, Hume, David A., Mowat, Allan M. and Randolph, Gwendalyn J. (2010). Unravelling mononuclear phagocyte heterogeneity. Nature Reviews Immunology, 10 (6), 453-460. doi: 10.1038/nri2784 |
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2010 Journal Article A conserved distal segment of the mouse CSF-1 receptor promoter is required for maximal expression of a reporter gene in macrophages and osteoclasts of transgenic miceOvchinnikov, Dmitry A., DeBats, Claire E. E., Sester, David P., Sweet, Matthew J. and Hume, David A. (2010). A conserved distal segment of the mouse CSF-1 receptor promoter is required for maximal expression of a reporter gene in macrophages and osteoclasts of transgenic mice. Journal of Leukocyte Biology, 87 (5), 815-822. doi: 10.1189/jlb.0809557 |
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2010 Journal Article Avian colony-stimulating factor 1 (CSF-1), interleukin-34 (IL-34), and CSF-1 receptor genes and gene productsGarceau, Valerie, Smith, Jacqueline, Paton, Ian R., Davey, Megan, Fares, Mario A., Sester, David P., Burt, David W. and Hume, David A. (2010). Avian colony-stimulating factor 1 (CSF-1), interleukin-34 (IL-34), and CSF-1 receptor genes and gene products. Journal of Leukocyte Biology, 87 (5), 753-764. doi: 10.1189/jlb.0909624 |
