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2010 Journal Article The combination of gene perturbation assay and ChIP-chip reveals functional direct target genes for IRF8 in THP-1 cellsKubosaki, A, Lindgren, G, Tagami, M, Simon, C, Tomaru, Y, Miura, H, Suzuki, T, Arner, E, Forrest, ARR, Irvine, KM, Schroder, K, Hasegawa, Y, Kanamori-Katayama, M, Rehli, M, Hume, DA, Kawai, J, Suzuki, M, Suzuki, H and Hayashizaki, Y (2010). The combination of gene perturbation assay and ChIP-chip reveals functional direct target genes for IRF8 in THP-1 cells. Molecular Immunology, 47 (14), 2295-2302. doi: 10.1016/j.molimm.2010.05.289 |
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2010 Journal Article Differential effects of selective HDAC inhibitors on macrophage inflammatory responses to the Toll-like receptor 4 agonist LPSHalili, Maria A., Andrews, Melanie R., Labzin, Larisa I., Schroder, Kate, Matthias, Gabriele, Cao, Chun, Lovelace, Erica, Reid, Robert C., Le, Giang T., Hume, David A., Irvine, Katharine M., Matthias, Patrick, Fairlie, David P. and Sweet, Matthew J. (2010). Differential effects of selective HDAC inhibitors on macrophage inflammatory responses to the Toll-like receptor 4 agonist LPS. Journal of Leukocyte Biology, 87 (6), 1103-1114. doi: 10.1189/jlb.0509363 |
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2010 Journal Article Functional clustering and lineage markers: insights into cellular differentiation and gene function from large-scale microarray studies of purified primary cell populationsHume, David A., Summers, Kim M., Raza, Sobia, Baillie, J. Kenneth and Freeman, Thomas C. (2010). Functional clustering and lineage markers: insights into cellular differentiation and gene function from large-scale microarray studies of purified primary cell populations. Genomics, 95 (6), 328-338. doi: 10.1016/j.ygeno.2010.03.002 |
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2010 Journal Article Unravelling mononuclear phagocyte heterogeneityGeissmann, Frederic, Gordon, Siamon, Hume, David A., Mowat, Allan M. and Randolph, Gwendalyn J. (2010). Unravelling mononuclear phagocyte heterogeneity. Nature Reviews Immunology, 10 (6), 453-460. doi: 10.1038/nri2784 |
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2010 Journal Article A conserved distal segment of the mouse CSF-1 receptor promoter is required for maximal expression of a reporter gene in macrophages and osteoclasts of transgenic miceOvchinnikov, Dmitry A., DeBats, Claire E. E., Sester, David P., Sweet, Matthew J. and Hume, David A. (2010). A conserved distal segment of the mouse CSF-1 receptor promoter is required for maximal expression of a reporter gene in macrophages and osteoclasts of transgenic mice. Journal of Leukocyte Biology, 87 (5), 815-822. doi: 10.1189/jlb.0809557 |
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2010 Journal Article Avian colony-stimulating factor 1 (CSF-1), interleukin-34 (IL-34), and CSF-1 receptor genes and gene productsGarceau, Valerie, Smith, Jacqueline, Paton, Ian R., Davey, Megan, Fares, Mario A., Sester, David P., Burt, David W. and Hume, David A. (2010). Avian colony-stimulating factor 1 (CSF-1), interleukin-34 (IL-34), and CSF-1 receptor genes and gene products. Journal of Leukocyte Biology, 87 (5), 753-764. doi: 10.1189/jlb.0909624 |
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2010 Journal Article An atlas of combinatorial transcriptional regulation in mouse and manRavasi, Timothy, Suzuki, Harukazu, Cannistraci, Carlo Vittorio, Katayama, Shintaro, Bajic, Vladimir B., Tan, Kai, Akalin, Altuna, Schmeier, Sebastian, Kanamori-Katayama, Mutsumi, Bertin, Nicolas, Carninci, Piero, Daub, Carsten O., Forrest, Alistair R.R., Gough, Julian, Grimmond, Sean, Han, Jung-Hoon, Hashimoto, Takehiro, Hide, Winston, Hofmann, Oliver, Kamburov, Atanas, Kaur, Mandeep, Kawaji, Hideya, Kubosaki, Atsutaka, Lassmann, Timo, van Nimwegen, Erik, MacPherson, Cameron Ross, Ogawa, Chihiro, Radovanovic, Aleksandar, Schwartz, Ariel ... Hayashizaki, Yoshihide (2010). An atlas of combinatorial transcriptional regulation in mouse and man. Cell, 141 (2), 369. doi: 10.1016/j.cell.2010.04.004 |
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2010 Journal Article Macrophages from BALB/c and CBA/Ca mice differ in their cellular responses to Streptococcus pneumoniaeRipoll, Vera M., Kadioglu, Aras, Cox, Roger, Hume, David A. and Denny, Paul (2010). Macrophages from BALB/c and CBA/Ca mice differ in their cellular responses to Streptococcus pneumoniae. Journal of Leukocyte Biology, 87 (4), 735-741. doi: 10.1189/jlb.0509359 |
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2010 Journal Article An atlas of combinatorial transcriptional regulation in mouse and manRavasi, Timothy, Suzuki, Harukazu, Cannistraci, Carlo Vittorio, Katayama, Shintaro, Bajic, Vladimir B., Tan, Kai, Akalin, Altuna, Schmeier, Sebastian, Kanamori-Katayama, Mutsumi, Carninci, Piero, Bertin, Nicholas, Daub, Cartsten O., Forrest, Alistair R. R., Gough, Julian, Grimmond, Sean, Han, Jung-Hoon, Hashimoto, Takehiro, Hide, Winston, Hofmann, Oliver, Kamburov, Atanas, Kaur, Mandeep, Kawaji, Hideya, Kubosaki, Atsutaka, Lassmann, Timo, van Nimwegen, Erik, MacPherson, Cameron Ross, Ogawa, Chihiro, Radovanovic, Aleksandar, Schwartz, Ariel ... Hayashizaki, Yoshihide (2010). An atlas of combinatorial transcriptional regulation in mouse and man. Cell, 140 (5), 744-752. doi: 10.1016/j.cell.2010.01.044 |
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2010 Journal Article A novel mouse model of inflammatory bowel disease links mammalian target of rapamycin-dependent hyperproliferation of colonic epithelium to inflammation-associated tumorigenesisDeng, Lin, Zhou, Jin-Feng, Sellers, Rani S., Li, Jiu-Feng, Nguyen, Andrew V., Wang, Yubao, Orlofsky, Amos, Liu, Qiang, Hume, David A., Pollard, Jeffrey W., Augenlicht, Leonard and Lin, Elaine Y. (2010). A novel mouse model of inflammatory bowel disease links mammalian target of rapamycin-dependent hyperproliferation of colonic epithelium to inflammation-associated tumorigenesis. American Journal of Pathology, 176 (2), 952-967. doi: 10.2353/ajpath.2010.090622 |
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2010 Journal Article Identification and characterisation of new inhibitors for the human hematopoietic prostaglandin D-2 synthaseWeber, Jane E., Oakley, Aaron J., Christ, Angelika N., Hayes, John D., Hall, Rhonda, Hume, David A., Board, Philip G., Smythe, Mark L. and Flanagan, Jack U. (2010). Identification and characterisation of new inhibitors for the human hematopoietic prostaglandin D-2 synthase. European Journal of Medicinal Chemistry, 45 (2), 447-454. doi: 10.1016/j.ejmech.2009.10.025 |
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2010 Journal Article Cellular plasticity of inflammatory myeloid cells in the peritoneal foreign body responseMooney, Jane E., Rolfe, Barbara E., Osborne, Geoffrey W., Sester, David P., van Rooijen, Nico, Campbell, Gordon R., Hume, David A. and Campbell, Julie H. (2010). Cellular plasticity of inflammatory myeloid cells in the peritoneal foreign body response. American Journal of Pathology, 176 (1), 369-380. doi: 10.2353/ajpath.2010.090545 |
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2010 Conference Publication Induction of microRNAs, mir-155, mir-222, mir-424 and mir-503, promotes monocytic differentiation through combinatorial regulationForrest, A. R. R., Kanamori-Katayama, M., Tomaru, Y., Lassmann, T., Ninomiya, N., Takahashi, Y., de Hoon, M. J. L., Kubosaki, A., Kaiho, A., Suzuki, M., Yasuda, J., Kawai, J., Hayashizaki, Y., Hume, D. A. and Suzuki, H. (2010). Induction of microRNAs, mir-155, mir-222, mir-424 and mir-503, promotes monocytic differentiation through combinatorial regulation. ELSEVIER SCI LTD. doi: 10.1016/j.diff.2010.09.048 |
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2010 Journal Article Induction of microRNAs, mir-155, mir-222, mir-424 and mir-503, promotes monocytic differentiation through combinatorial regulationForrest, A. R.R., Kanamori-Katayama, M., Tomaru, Y., Lassmann, T., Ninomiya, N., Takahashi, Y., De Hoon, M. J.L., Kubosaki, A., Kaiho, A., Suzuki, M., Yasuda, J., Kawai, J., Hayashizaki, Y., Hume, D. A. and Suzuki, H. (2010). Induction of microRNAs, mir-155, mir-222, mir-424 and mir-503, promotes monocytic differentiation through combinatorial regulation. Leukemia, 24 (2), 460-466. doi: 10.1038/leu.2009.246 |
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2009 Journal Article Beta-arrestin 2 is required for complement C1q expression in macrophages and constrains factor-independent survivalLattin, J. E., Greenwood, K. P., Daly, N. L., Kelly, G, Zidar, D. A., Clark, R. J., Thomas, W. G., Kellie, Stuart, Craik, D. J., Hume, D. A. and Sweet, M. J. (2009). Beta-arrestin 2 is required for complement C1q expression in macrophages and constrains factor-independent survival. Molecular Immunology, 47 (2-3), 340-347. doi: 10.1016/j.molimm.2009.09.012 |
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2009 Journal Article Experimental and bioinformatic characterisation of the promoter region of the Marfan syndrome gene, FBN1Summers, Kim M., Bokil, Nilesh J., Baisden, John M., West, Malcolm J., Sweet, Matthew J., Raggatt, Liza J. and Hume, David A. (2009). Experimental and bioinformatic characterisation of the promoter region of the Marfan syndrome gene, FBN1. Genomics, 94 (4), 233-240. doi: 10.1016/j.ygeno.2009.06.005 |
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2009 Book Chapter The impact of CAGE data on understanding macrophage transcriptional biologyHume, David A., Schroder, Kate and Irvine, Katharine M. (2009). The impact of CAGE data on understanding macrophage transcriptional biology. Cap-Analysis Gene Expression (CAGE): The Science of Decoding Genes Transcription. (pp. 227-243) Pan Stanford Publishing Pte. Ltd.. doi: 10.4032/9789814241359 |
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2009 Journal Article Docosahexaenoic acid attenuates microglial activation and delays early retinal degenerationEbert, Stefanie, Weigelt, Karin, Walczak, Yana, Drobnik, Wolfgang, Mauerer, Richard, Hume, David A., Weber, Bernhard H. F. and Langmann, Thomas (2009). Docosahexaenoic acid attenuates microglial activation and delays early retinal degeneration. Journal of Neurochemistry, 110 (6), 1863-1875. doi: 10.1111/j.1471-4159.2009.06286.x |
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2009 Journal Article Corrigendum: Tiny RNAs associated with transcription start sites in animals (vol 41, pg 572, 2009)Taft, Ryan J., Glazov, Evgeny A., Cloonan, Nicole, Simons, Cas, Stephen, Stuart, Faulkner, Geoffrey J., Lassmann, Timo, Forrest, Alistair R. R., Grimmond, Sean M., Schroder, Kate, Irvine, Katharine, Arakawa, Takahiro, Nakamura, Mari, Kubosaki, Atsutaka, Hayashida, Kengo, Kawazu, Chika, Murata, Mitsuyoshi, Nishiyori, Hiromi, Fukuda, Shiro, Kawai, Jun, Daub, Carsten O., Hume, David A., Suzuki, Harukazu, Orlando, Valerio, Carninci, Piero, Hayashizaki, Yoshihide and Mattick, John S. (2009). Corrigendum: Tiny RNAs associated with transcription start sites in animals (vol 41, pg 572, 2009). Nature Genetics, 41 (7), 859-859. doi: 10.1038/ng0709-859a |
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2009 Journal Article Selective induction of the Notch ligand Jagged -1 in macrophages by soluble egg antigen from Schistosoma mansoni involves ERK signalingGoh, Felicia, Irvine, Katharine M., Lovelace, Erica, Donnelly, Sheila, Jones, Malcolm K ., Brion, Kristian, Hume, David A., Kotze, Andrew C., Dalton John P., Ingham, Aaron and Sweet, Matthew J. (2009). Selective induction of the Notch ligand Jagged -1 in macrophages by soluble egg antigen from Schistosoma mansoni involves ERK signaling. Immunology, 127 (3), 326-337. doi: 10.1111/j.1365-2567.2008.02979.x |
