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2010

Journal Article

CSF-1, IGF-1, and the control of postnatal growth and development

Gow, Deborah J., Sester, David P. and Hume, David A. (2010). CSF-1, IGF-1, and the control of postnatal growth and development. Journal of Leukocyte Biology, 88 (3), 475-481. doi: 10.1189/jlb.0310158

CSF-1, IGF-1, and the control of postnatal growth and development

2010

Journal Article

Meta-analysis of lineage-specific gene expression signatures in mouse leukocyte populations

Mabbott, Neil A., Baillie, J. Kenneth, Hume, David A. and Freeman, Tom C. (2010). Meta-analysis of lineage-specific gene expression signatures in mouse leukocyte populations. Immunobiology, 215 (9-10), 724-736. doi: 10.1016/j.imbio.2010.05.012

Meta-analysis of lineage-specific gene expression signatures in mouse leukocyte populations

2010

Journal Article

The combination of gene perturbation assay and ChIP-chip reveals functional direct target genes for IRF8 in THP-1 cells

Kubosaki, A, Lindgren, G, Tagami, M, Simon, C, Tomaru, Y, Miura, H, Suzuki, T, Arner, E, Forrest, ARR, Irvine, KM, Schroder, K, Hasegawa, Y, Kanamori-Katayama, M, Rehli, M, Hume, DA, Kawai, J, Suzuki, M, Suzuki, H and Hayashizaki, Y (2010). The combination of gene perturbation assay and ChIP-chip reveals functional direct target genes for IRF8 in THP-1 cells. Molecular Immunology, 47 (14), 2295-2302. doi: 10.1016/j.molimm.2010.05.289

The combination of gene perturbation assay and ChIP-chip reveals functional direct target genes for IRF8 in THP-1 cells

2010

Journal Article

Functional clustering and lineage markers: insights into cellular differentiation and gene function from large-scale microarray studies of purified primary cell populations

Hume, David A., Summers, Kim M., Raza, Sobia, Baillie, J. Kenneth and Freeman, Thomas C. (2010). Functional clustering and lineage markers: insights into cellular differentiation and gene function from large-scale microarray studies of purified primary cell populations. Genomics, 95 (6), 328-338. doi: 10.1016/j.ygeno.2010.03.002

Functional clustering and lineage markers: insights into cellular differentiation and gene function from large-scale microarray studies of purified primary cell populations

2010

Journal Article

Differential effects of selective HDAC inhibitors on macrophage inflammatory responses to the Toll-like receptor 4 agonist LPS

Halili, Maria A., Andrews, Melanie R., Labzin, Larisa I., Schroder, Kate, Matthias, Gabriele, Cao, Chun, Lovelace, Erica, Reid, Robert C., Le, Giang T., Hume, David A., Irvine, Katharine M., Matthias, Patrick, Fairlie, David P. and Sweet, Matthew J. (2010). Differential effects of selective HDAC inhibitors on macrophage inflammatory responses to the Toll-like receptor 4 agonist LPS. Journal of Leukocyte Biology, 87 (6), 1103-1114. doi: 10.1189/jlb.0509363

Differential effects of selective HDAC inhibitors on macrophage inflammatory responses to the Toll-like receptor 4 agonist LPS

2010

Journal Article

Avian colony-stimulating factor 1 (CSF-1), interleukin-34 (IL-34), and CSF-1 receptor genes and gene products

Garceau, Valerie, Smith, Jacqueline, Paton, Ian R., Davey, Megan, Fares, Mario A., Sester, David P., Burt, David W. and Hume, David A. (2010). Avian colony-stimulating factor 1 (CSF-1), interleukin-34 (IL-34), and CSF-1 receptor genes and gene products. Journal of Leukocyte Biology, 87 (5), 753-764. doi: 10.1189/jlb.0909624

Avian colony-stimulating factor 1 (CSF-1), interleukin-34 (IL-34), and CSF-1 receptor genes and gene products

2010

Journal Article

A conserved distal segment of the mouse CSF-1 receptor promoter is required for maximal expression of a reporter gene in macrophages and osteoclasts of transgenic mice

Ovchinnikov, Dmitry A., DeBats, Claire E. E., Sester, David P., Sweet, Matthew J. and Hume, David A. (2010). A conserved distal segment of the mouse CSF-1 receptor promoter is required for maximal expression of a reporter gene in macrophages and osteoclasts of transgenic mice. Journal of Leukocyte Biology, 87 (5), 815-822. doi: 10.1189/jlb.0809557

A conserved distal segment of the mouse CSF-1 receptor promoter is required for maximal expression of a reporter gene in macrophages and osteoclasts of transgenic mice

2010

Journal Article

Unravelling mononuclear phagocyte heterogeneity

Geissmann, Frederic, Gordon, Siamon, Hume, David A., Mowat, Allan M. and Randolph, Gwendalyn J. (2010). Unravelling mononuclear phagocyte heterogeneity. Nature Reviews Immunology, 10 (6), 453-460. doi: 10.1038/nri2784

Unravelling mononuclear phagocyte heterogeneity

2010

Journal Article

Macrophages from BALB/c and CBA/Ca mice differ in their cellular responses to Streptococcus pneumoniae

Ripoll, Vera M., Kadioglu, Aras, Cox, Roger, Hume, David A. and Denny, Paul (2010). Macrophages from BALB/c and CBA/Ca mice differ in their cellular responses to Streptococcus pneumoniae. Journal of Leukocyte Biology, 87 (4), 735-741. doi: 10.1189/jlb.0509359

Macrophages from BALB/c and CBA/Ca mice differ in their cellular responses to Streptococcus pneumoniae

2010

Journal Article

An atlas of combinatorial transcriptional regulation in mouse and man

Ravasi, Timothy, Suzuki, Harukazu, Cannistraci, Carlo Vittorio, Katayama, Shintaro, Bajic, Vladimir B., Tan, Kai, Akalin, Altuna, Schmeier, Sebastian, Kanamori-Katayama, Mutsumi, Bertin, Nicolas, Carninci, Piero, Daub, Carsten O., Forrest, Alistair R.R., Gough, Julian, Grimmond, Sean, Han, Jung-Hoon, Hashimoto, Takehiro, Hide, Winston, Hofmann, Oliver, Kamburov, Atanas, Kaur, Mandeep, Kawaji, Hideya, Kubosaki, Atsutaka, Lassmann, Timo, van Nimwegen, Erik, MacPherson, Cameron Ross, Ogawa, Chihiro, Radovanovic, Aleksandar, Schwartz, Ariel ... Hayashizaki, Yoshihide (2010). An atlas of combinatorial transcriptional regulation in mouse and man. Cell, 141 (2), 369. doi: 10.1016/j.cell.2010.04.004

An atlas of combinatorial transcriptional regulation in mouse and man

2010

Journal Article

An atlas of combinatorial transcriptional regulation in mouse and man

Ravasi, Timothy, Suzuki, Harukazu, Cannistraci, Carlo Vittorio, Katayama, Shintaro, Bajic, Vladimir B., Tan, Kai, Akalin, Altuna, Schmeier, Sebastian, Kanamori-Katayama, Mutsumi, Carninci, Piero, Bertin, Nicholas, Daub, Cartsten O., Forrest, Alistair R. R., Gough, Julian, Grimmond, Sean, Han, Jung-Hoon, Hashimoto, Takehiro, Hide, Winston, Hofmann, Oliver, Kamburov, Atanas, Kaur, Mandeep, Kawaji, Hideya, Kubosaki, Atsutaka, Lassmann, Timo, van Nimwegen, Erik, MacPherson, Cameron Ross, Ogawa, Chihiro, Radovanovic, Aleksandar, Schwartz, Ariel ... Hayashizaki, Yoshihide (2010). An atlas of combinatorial transcriptional regulation in mouse and man. Cell, 140 (5), 744-752. doi: 10.1016/j.cell.2010.01.044

An atlas of combinatorial transcriptional regulation in mouse and man

2010

Journal Article

Identification and characterisation of new inhibitors for the human hematopoietic prostaglandin D-2 synthase

Weber, Jane E., Oakley, Aaron J., Christ, Angelika N., Hayes, John D., Hall, Rhonda, Hume, David A., Board, Philip G., Smythe, Mark L. and Flanagan, Jack U. (2010). Identification and characterisation of new inhibitors for the human hematopoietic prostaglandin D-2 synthase. European Journal of Medicinal Chemistry, 45 (2), 447-454. doi: 10.1016/j.ejmech.2009.10.025

Identification and characterisation of new inhibitors for the human hematopoietic prostaglandin D-2 synthase

2010

Journal Article

A novel mouse model of inflammatory bowel disease links mammalian target of rapamycin-dependent hyperproliferation of colonic epithelium to inflammation-associated tumorigenesis

Deng, Lin, Zhou, Jin-Feng, Sellers, Rani S., Li, Jiu-Feng, Nguyen, Andrew V., Wang, Yubao, Orlofsky, Amos, Liu, Qiang, Hume, David A., Pollard, Jeffrey W., Augenlicht, Leonard and Lin, Elaine Y. (2010). A novel mouse model of inflammatory bowel disease links mammalian target of rapamycin-dependent hyperproliferation of colonic epithelium to inflammation-associated tumorigenesis. American Journal of Pathology, 176 (2), 952-967. doi: 10.2353/ajpath.2010.090622

A novel mouse model of inflammatory bowel disease links mammalian target of rapamycin-dependent hyperproliferation of colonic epithelium to inflammation-associated tumorigenesis

2010

Conference Publication

Induction of microRNAs, mir-155, mir-222, mir-424 and mir-503, promotes monocytic differentiation through combinatorial regulation

Forrest, A. R. R., Kanamori-Katayama, M., Tomaru, Y., Lassmann, T., Ninomiya, N., Takahashi, Y., de Hoon, M. J. L., Kubosaki, A., Kaiho, A., Suzuki, M., Yasuda, J., Kawai, J., Hayashizaki, Y., Hume, D. A. and Suzuki, H. (2010). Induction of microRNAs, mir-155, mir-222, mir-424 and mir-503, promotes monocytic differentiation through combinatorial regulation. ELSEVIER SCI LTD. doi: 10.1016/j.diff.2010.09.048

Induction of microRNAs, mir-155, mir-222, mir-424 and mir-503, promotes monocytic differentiation through combinatorial regulation

2010

Journal Article

Induction of microRNAs, mir-155, mir-222, mir-424 and mir-503, promotes monocytic differentiation through combinatorial regulation

Forrest, A. R.R., Kanamori-Katayama, M., Tomaru, Y., Lassmann, T., Ninomiya, N., Takahashi, Y., De Hoon, M. J.L., Kubosaki, A., Kaiho, A., Suzuki, M., Yasuda, J., Kawai, J., Hayashizaki, Y., Hume, D. A. and Suzuki, H. (2010). Induction of microRNAs, mir-155, mir-222, mir-424 and mir-503, promotes monocytic differentiation through combinatorial regulation. Leukemia, 24 (2), 460-466. doi: 10.1038/leu.2009.246

Induction of microRNAs, mir-155, mir-222, mir-424 and mir-503, promotes monocytic differentiation through combinatorial regulation

2010

Journal Article

Cellular plasticity of inflammatory myeloid cells in the peritoneal foreign body response

Mooney, Jane E., Rolfe, Barbara E., Osborne, Geoffrey W., Sester, David P., van Rooijen, Nico, Campbell, Gordon R., Hume, David A. and Campbell, Julie H. (2010). Cellular plasticity of inflammatory myeloid cells in the peritoneal foreign body response. American Journal of Pathology, 176 (1), 369-380. doi: 10.2353/ajpath.2010.090545

Cellular plasticity of inflammatory myeloid cells in the peritoneal foreign body response

2009

Journal Article

Beta-arrestin 2 is required for complement C1q expression in macrophages and constrains factor-independent survival

Lattin, J. E., Greenwood, K. P., Daly, N. L., Kelly, G, Zidar, D. A., Clark, R. J., Thomas, W. G., Kellie, Stuart, Craik, D. J., Hume, D. A. and Sweet, M. J. (2009). Beta-arrestin 2 is required for complement C1q expression in macrophages and constrains factor-independent survival. Molecular Immunology, 47 (2-3), 340-347. doi: 10.1016/j.molimm.2009.09.012

Beta-arrestin 2 is required for complement C1q expression in macrophages and constrains factor-independent survival

2009

Journal Article

Experimental and bioinformatic characterisation of the promoter region of the Marfan syndrome gene, FBN1

Summers, Kim M., Bokil, Nilesh J., Baisden, John M., West, Malcolm J., Sweet, Matthew J., Raggatt, Liza J. and Hume, David A. (2009). Experimental and bioinformatic characterisation of the promoter region of the Marfan syndrome gene, FBN1. Genomics, 94 (4), 233-240. doi: 10.1016/j.ygeno.2009.06.005

Experimental and bioinformatic characterisation of the promoter region of the Marfan syndrome gene, FBN1

2009

Book Chapter

The impact of CAGE data on understanding macrophage transcriptional biology

Hume, David A., Schroder, Kate and Irvine, Katharine M. (2009). The impact of CAGE data on understanding macrophage transcriptional biology. Cap-Analysis Gene Expression (CAGE): The Science of Decoding Genes Transcription. (pp. 227-243) Pan Stanford Publishing Pte. Ltd.. doi: 10.4032/9789814241359

The impact of CAGE data on understanding macrophage transcriptional biology

2009

Journal Article

Docosahexaenoic acid attenuates microglial activation and delays early retinal degeneration

Ebert, Stefanie, Weigelt, Karin, Walczak, Yana, Drobnik, Wolfgang, Mauerer, Richard, Hume, David A., Weber, Bernhard H. F. and Langmann, Thomas (2009). Docosahexaenoic acid attenuates microglial activation and delays early retinal degeneration. Journal of Neurochemistry, 110 (6), 1863-1875. doi: 10.1111/j.1471-4159.2009.06286.x

Docosahexaenoic acid attenuates microglial activation and delays early retinal degeneration