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2010

Journal Article

Macrophages from BALB/c and CBA/Ca mice differ in their cellular responses to Streptococcus pneumoniae

Ripoll, Vera M., Kadioglu, Aras, Cox, Roger, Hume, David A. and Denny, Paul (2010). Macrophages from BALB/c and CBA/Ca mice differ in their cellular responses to Streptococcus pneumoniae. Journal of Leukocyte Biology, 87 (4), 735-741. doi: 10.1189/jlb.0509359

Macrophages from BALB/c and CBA/Ca mice differ in their cellular responses to Streptococcus pneumoniae

2010

Journal Article

An atlas of combinatorial transcriptional regulation in mouse and man

Ravasi, Timothy, Suzuki, Harukazu, Cannistraci, Carlo Vittorio, Katayama, Shintaro, Bajic, Vladimir B., Tan, Kai, Akalin, Altuna, Schmeier, Sebastian, Kanamori-Katayama, Mutsumi, Bertin, Nicolas, Carninci, Piero, Daub, Carsten O., Forrest, Alistair R.R., Gough, Julian, Grimmond, Sean, Han, Jung-Hoon, Hashimoto, Takehiro, Hide, Winston, Hofmann, Oliver, Kamburov, Atanas, Kaur, Mandeep, Kawaji, Hideya, Kubosaki, Atsutaka, Lassmann, Timo, van Nimwegen, Erik, MacPherson, Cameron Ross, Ogawa, Chihiro, Radovanovic, Aleksandar, Schwartz, Ariel ... Hayashizaki, Yoshihide (2010). An atlas of combinatorial transcriptional regulation in mouse and man. Cell, 141 (2), 369. doi: 10.1016/j.cell.2010.04.004

An atlas of combinatorial transcriptional regulation in mouse and man

2010

Journal Article

An atlas of combinatorial transcriptional regulation in mouse and man

Ravasi, Timothy, Suzuki, Harukazu, Cannistraci, Carlo Vittorio, Katayama, Shintaro, Bajic, Vladimir B., Tan, Kai, Akalin, Altuna, Schmeier, Sebastian, Kanamori-Katayama, Mutsumi, Carninci, Piero, Bertin, Nicholas, Daub, Cartsten O., Forrest, Alistair R. R., Gough, Julian, Grimmond, Sean, Han, Jung-Hoon, Hashimoto, Takehiro, Hide, Winston, Hofmann, Oliver, Kamburov, Atanas, Kaur, Mandeep, Kawaji, Hideya, Kubosaki, Atsutaka, Lassmann, Timo, van Nimwegen, Erik, MacPherson, Cameron Ross, Ogawa, Chihiro, Radovanovic, Aleksandar, Schwartz, Ariel ... Hayashizaki, Yoshihide (2010). An atlas of combinatorial transcriptional regulation in mouse and man. Cell, 140 (5), 744-752. doi: 10.1016/j.cell.2010.01.044

An atlas of combinatorial transcriptional regulation in mouse and man

2010

Journal Article

A novel mouse model of inflammatory bowel disease links mammalian target of rapamycin-dependent hyperproliferation of colonic epithelium to inflammation-associated tumorigenesis

Deng, Lin, Zhou, Jin-Feng, Sellers, Rani S., Li, Jiu-Feng, Nguyen, Andrew V., Wang, Yubao, Orlofsky, Amos, Liu, Qiang, Hume, David A., Pollard, Jeffrey W., Augenlicht, Leonard and Lin, Elaine Y. (2010). A novel mouse model of inflammatory bowel disease links mammalian target of rapamycin-dependent hyperproliferation of colonic epithelium to inflammation-associated tumorigenesis. American Journal of Pathology, 176 (2), 952-967. doi: 10.2353/ajpath.2010.090622

A novel mouse model of inflammatory bowel disease links mammalian target of rapamycin-dependent hyperproliferation of colonic epithelium to inflammation-associated tumorigenesis

2010

Journal Article

Identification and characterisation of new inhibitors for the human hematopoietic prostaglandin D-2 synthase

Weber, Jane E., Oakley, Aaron J., Christ, Angelika N., Hayes, John D., Hall, Rhonda, Hume, David A., Board, Philip G., Smythe, Mark L. and Flanagan, Jack U. (2010). Identification and characterisation of new inhibitors for the human hematopoietic prostaglandin D-2 synthase. European Journal of Medicinal Chemistry, 45 (2), 447-454. doi: 10.1016/j.ejmech.2009.10.025

Identification and characterisation of new inhibitors for the human hematopoietic prostaglandin D-2 synthase

2010

Journal Article

Cellular plasticity of inflammatory myeloid cells in the peritoneal foreign body response

Mooney, Jane E., Rolfe, Barbara E., Osborne, Geoffrey W., Sester, David P., van Rooijen, Nico, Campbell, Gordon R., Hume, David A. and Campbell, Julie H. (2010). Cellular plasticity of inflammatory myeloid cells in the peritoneal foreign body response. American Journal of Pathology, 176 (1), 369-380. doi: 10.2353/ajpath.2010.090545

Cellular plasticity of inflammatory myeloid cells in the peritoneal foreign body response

2010

Conference Publication

Induction of microRNAs, mir-155, mir-222, mir-424 and mir-503, promotes monocytic differentiation through combinatorial regulation

Forrest, A. R. R., Kanamori-Katayama, M., Tomaru, Y., Lassmann, T., Ninomiya, N., Takahashi, Y., de Hoon, M. J. L., Kubosaki, A., Kaiho, A., Suzuki, M., Yasuda, J., Kawai, J., Hayashizaki, Y., Hume, D. A. and Suzuki, H. (2010). Induction of microRNAs, mir-155, mir-222, mir-424 and mir-503, promotes monocytic differentiation through combinatorial regulation. ELSEVIER SCI LTD. doi: 10.1016/j.diff.2010.09.048

Induction of microRNAs, mir-155, mir-222, mir-424 and mir-503, promotes monocytic differentiation through combinatorial regulation

2010

Journal Article

Induction of microRNAs, mir-155, mir-222, mir-424 and mir-503, promotes monocytic differentiation through combinatorial regulation

Forrest, A. R.R., Kanamori-Katayama, M., Tomaru, Y., Lassmann, T., Ninomiya, N., Takahashi, Y., De Hoon, M. J.L., Kubosaki, A., Kaiho, A., Suzuki, M., Yasuda, J., Kawai, J., Hayashizaki, Y., Hume, D. A. and Suzuki, H. (2010). Induction of microRNAs, mir-155, mir-222, mir-424 and mir-503, promotes monocytic differentiation through combinatorial regulation. Leukemia, 24 (2), 460-466. doi: 10.1038/leu.2009.246

Induction of microRNAs, mir-155, mir-222, mir-424 and mir-503, promotes monocytic differentiation through combinatorial regulation

2009

Journal Article

Beta-arrestin 2 is required for complement C1q expression in macrophages and constrains factor-independent survival

Lattin, J. E., Greenwood, K. P., Daly, N. L., Kelly, G, Zidar, D. A., Clark, R. J., Thomas, W. G., Kellie, Stuart, Craik, D. J., Hume, D. A. and Sweet, M. J. (2009). Beta-arrestin 2 is required for complement C1q expression in macrophages and constrains factor-independent survival. Molecular Immunology, 47 (2-3), 340-347. doi: 10.1016/j.molimm.2009.09.012

Beta-arrestin 2 is required for complement C1q expression in macrophages and constrains factor-independent survival

2009

Journal Article

Experimental and bioinformatic characterisation of the promoter region of the Marfan syndrome gene, FBN1

Summers, Kim M., Bokil, Nilesh J., Baisden, John M., West, Malcolm J., Sweet, Matthew J., Raggatt, Liza J. and Hume, David A. (2009). Experimental and bioinformatic characterisation of the promoter region of the Marfan syndrome gene, FBN1. Genomics, 94 (4), 233-240. doi: 10.1016/j.ygeno.2009.06.005

Experimental and bioinformatic characterisation of the promoter region of the Marfan syndrome gene, FBN1

2009

Book Chapter

The impact of CAGE data on understanding macrophage transcriptional biology

Hume, David A., Schroder, Kate and Irvine, Katharine M. (2009). The impact of CAGE data on understanding macrophage transcriptional biology. Cap-Analysis Gene Expression (CAGE): The Science of Decoding Genes Transcription. (pp. 227-243) Pan Stanford Publishing Pte. Ltd.. doi: 10.4032/9789814241359

The impact of CAGE data on understanding macrophage transcriptional biology

2009

Journal Article

Docosahexaenoic acid attenuates microglial activation and delays early retinal degeneration

Ebert, Stefanie, Weigelt, Karin, Walczak, Yana, Drobnik, Wolfgang, Mauerer, Richard, Hume, David A., Weber, Bernhard H. F. and Langmann, Thomas (2009). Docosahexaenoic acid attenuates microglial activation and delays early retinal degeneration. Journal of Neurochemistry, 110 (6), 1863-1875. doi: 10.1111/j.1471-4159.2009.06286.x

Docosahexaenoic acid attenuates microglial activation and delays early retinal degeneration

2009

Journal Article

Selective induction of the Notch ligand Jagged -1 in macrophages by soluble egg antigen from Schistosoma mansoni involves ERK signaling

Goh, Felicia, Irvine, Katharine M., Lovelace, Erica, Donnelly, Sheila, Jones, Malcolm K ., Brion, Kristian, Hume, David A., Kotze, Andrew C., Dalton John P., Ingham, Aaron and Sweet, Matthew J. (2009). Selective induction of the Notch ligand Jagged -1 in macrophages by soluble egg antigen from Schistosoma mansoni involves ERK signaling. Immunology, 127 (3), 326-337. doi: 10.1111/j.1365-2567.2008.02979.x

Selective induction of the Notch ligand Jagged -1 in macrophages by soluble egg antigen from Schistosoma mansoni involves ERK signaling

2009

Journal Article

Corrigendum: Tiny RNAs associated with transcription start sites in animals (vol 41, pg 572, 2009)

Taft, Ryan J., Glazov, Evgeny A., Cloonan, Nicole, Simons, Cas, Stephen, Stuart, Faulkner, Geoffrey J., Lassmann, Timo, Forrest, Alistair R. R., Grimmond, Sean M., Schroder, Kate, Irvine, Katharine, Arakawa, Takahiro, Nakamura, Mari, Kubosaki, Atsutaka, Hayashida, Kengo, Kawazu, Chika, Murata, Mitsuyoshi, Nishiyori, Hiromi, Fukuda, Shiro, Kawai, Jun, Daub, Carsten O., Hume, David A., Suzuki, Harukazu, Orlando, Valerio, Carninci, Piero, Hayashizaki, Yoshihide and Mattick, John S. (2009). Corrigendum: Tiny RNAs associated with transcription start sites in animals (vol 41, pg 572, 2009). Nature Genetics, 41 (7), 859-859. doi: 10.1038/ng0709-859a

Corrigendum: Tiny RNAs associated with transcription start sites in animals (vol 41, pg 572, 2009)

2009

Journal Article

CD148/DEP-1 association with areas of cytoskeletal organisation in macrophages

Dave, R. K., Hume, D. A., Elsegood, C and Kellie, S (2009). CD148/DEP-1 association with areas of cytoskeletal organisation in macrophages. Experimental Cell Research, 315 (10), 1734-1744. doi: 10.1016/j.yexcr.2009.02.023

CD148/DEP-1 association with areas of cytoskeletal organisation in macrophages

2009

Journal Article

Tiny RNAs associated with transcription start sites in animals

Taft, RJ, Glazov, EA, Cloonan, N, Simons, C, Stephen, S, Faulkner, GJ, Lassmann, T, Forrest, ARR, Grimmond, SM, Schroder, K, Irvine, K, Arakawa, T, Nakamura, M, Kubosaki, A, Hayashida, K, Kawazu, C, Murata, M, Nishiyori, H, Fukuda, S, Kawai, J, Daub, CO, Hume, DA, Suzuki, H, Orlando, V, Carninci, P, Hayashizaki, Y and Mattick, JS (2009). Tiny RNAs associated with transcription start sites in animals. Nature Genetics, 41 (5), 572-578. doi: 10.1038/ng.312

Tiny RNAs associated with transcription start sites in animals

2009

Journal Article

The regulated retrotransposon transcriptome of mammalian cells

Faulkner, Geoffrey J., Kimura, Yasumasa, Daub, Carsten O., Wani, Shivangi, Plessy, Charles, Irvine, Katharine M., Schroder, Kate, Cloonan, Nicole, Steptoe, Anita L., Lassmann, Timo, Waki, Kazunori, Hornig, Nadine, Arakawa, Takahiro, Takahashi, Hazuki, Kawai, Jun, Forrest, Alistair R. R., Suzuki, Harukazu, Hayashizaki, Yoshihide, Hume, David A., Orlando, Valerio, Grimmond, Sean M. and Carninci, Piero (2009). The regulated retrotransposon transcriptome of mammalian cells. Nature Genetics, 41 (5), 563-571. doi: 10.1038/ng.368

The regulated retrotransposon transcriptome of mammalian cells

2009

Journal Article

Data-driven normalization strategies for high-throughput quantitative RT-PCR

Mar, Jessica C., Kimura, Yasumasa, Schroder, Kate, Irvine, Katherine M., Hayashizaki, Yoshihide, Suzuki, Harukazu, Hume, David and Quackenbush, John (2009). Data-driven normalization strategies for high-throughput quantitative RT-PCR. BMC Bioinformatics, 10 (1) 110, 110.1-110.10. doi: 10.1186/1471-2105-10-110

Data-driven normalization strategies for high-throughput quantitative RT-PCR

2009

Journal Article

The FANTOM web resource: from mammalian transcriptional landscape to its dynamic regulation

Kawaji, H, Severin, J, Lizio, M, Waterhouse, A, Katayama, S, Irvine, K. M., Hume, D. A., Forrest, A. R. R., Suzuki, H, Carninci, P, Hayashizaki, Y and Daub, C. O. (2009). The FANTOM web resource: from mammalian transcriptional landscape to its dynamic regulation. Genome Biology, 10 (4) R40. doi: 10.1186/gb-2009-10-4-r40

The FANTOM web resource: from mammalian transcriptional landscape to its dynamic regulation

2009

Journal Article

FANTOM4 EdgeExpressDB: an integrated database of promoters, genes, microRNAs, expression dynamics and regulatory interactions

Severin, Jessica, Waterhouse, Andrew M., Kawaji, Hideya, Lassmann, Timo, van Nimwegen, Erik, Balwierz, Piotr J., de Hoon, Michiel J. L., Hume, David A., Carninci, Piero, Hayashizaki, Yoshihide, Suzuki, Harukazu, Daub, Carsten O. and Forrest, Alistair R. R. (2009). FANTOM4 EdgeExpressDB: an integrated database of promoters, genes, microRNAs, expression dynamics and regulatory interactions. Genome Biology, 10 (4) R39. doi: 10.1186/gb-2009-10-4-r39

FANTOM4 EdgeExpressDB: an integrated database of promoters, genes, microRNAs, expression dynamics and regulatory interactions