
Overview
Background
Professor Michael Monteiro has established an international reputation in the field of 'living' radical polymerization to create complex polymer architectures. He is now building designer polymers for various biomedical applications, including vaccines, drug delivery and stem cells. He is dedicated to translating research into commercial outcomes, with 7 PCT and provisional patents since 2005 and start-up company DendriMed Pty Ltd. He was awarded an ARC QEII Fellowship in 2004 and an ARC Future Fellowship in 2009. He has attracted ARC and NHMRC grants; and Queensland State Government funding in excess of $7 million.
International links
Professor Monteiro has built a strong collaboration with Professor Virgil Percec from the University of Pennsylvania to develop and understand the new SET-LRP. He has developed a collaboration with Professor Rachel O'Reilly from the University of Warwick to develop nanoreactors that mimic enzyme activity. In collaboration with Professor Eugenia Kumacheva from the University of Toronto, they developed temperature responsive micron-sized particles from encapsulation of cells.
Availability
- Professor Michael Monteiro is:
- Available for supervision
- Media expert
Fields of research
Research impacts
Research
Designer polymers: Synthesis of complex polymer architectures.
Professor Monteiro's research aims to develop methods of synthesising complex polymer architectures in water, with controlled particle size, molecular weight and morphology. By understanding the structure-property relations of these novel nanomaterials, targeted properties can be manufactured for vaccine and drug delivery. Easily recycled polymers that could be used in a variety of products have been synthesised.
Memberships, funding and patents
- Editorial Advisory Boards: Biomacromolecules (ACS Journal) (2013- ), Macromolecules (ACS Journal) (2008-2010), Journal of Polymer Science Part A Polymer Chemistry (2009-)
- ARC Funding: DP120100973 Prof MJ Monteiro; Dr TP Munro, On-demand scaffolds for directed stem cell differentiation
- Selected Patents: (i) Release Media Prov. AU2012902396, (ii) Polymeric dendrimers for siRNA delivery Prov. AU2012903138
Awards and plenaries
2013 UNESCO, Stellenbosch, SA Plenary 2013 ACS, New Orleans., USA – Invited lecture 2013 IPCG, Shanghi, China, Invited and Co-chair 2012 Australian Polymer Symposium, Hobart, Keynote 2012 IUAPC POC14, Qatar, Keynote 2011 Australian Leadership Award (ADC)
Works
Search Professor Michael Monteiro’s works on UQ eSpace
2014
Journal Article
Thermoresponsive worms for expansion and release of human embryonic stem cells
Chen, Xiaoli, Prowse, Andrew B. J., Jia, Zhongfan, Tellier, Helena, Munro,Trent P., Gray, Peter P. and Monteiro, Michael J. (2014). Thermoresponsive worms for expansion and release of human embryonic stem cells. Biomacromolecules, 15 (3), 844-855. doi: 10.1021/bm401702h
2014
Journal Article
Functionalized large pore mesoporous silica nanoparticles for gene delivery featuring controlled release and co-delivery
Hartono, Sandy Budi, Phuoc, Nghia Truong, Yu, Meihua, Jia, Zhongfan, Monteiro, Michael J., Qiao, Shizhang and Yu, Chengzhong (2014). Functionalized large pore mesoporous silica nanoparticles for gene delivery featuring controlled release and co-delivery. Journal of Materials Chemistry B, 2 (16), 718-726. doi: 10.1039/C3TB21015D
2014
Conference Publication
Multifunctional nanoworms and nanorods and functional membranes
Monteiro, Michael J. and Jia, Zhongfan (2014). Multifunctional nanoworms and nanorods and functional membranes. 248th National Meeting of the American Chemical Society (ACS), San Francisco CA, United States, 10-14 August 2014. Washington, DC United States: American Chemical Society.
2014
Journal Article
Nanoparticles of Well-defined 4-Arm stars made using nanoreactors in water
Sebakhy, Khaled O., Gavrilov, Mikhail, Valade, David, Jia, Zhongfan and Monteiro, Michael J. (2014). Nanoparticles of Well-defined 4-Arm stars made using nanoreactors in water. Macromolecular Rapid Communications, 35 (2), 193-197. doi: 10.1002/marc.201300665
2014
Conference Publication
Synthesis of therapeutic vaccine against cervical cancer
Skwarczynski, Mariusz, Liu, Tzu-Yu, Hussein, Waleed M., Jia, Zhongfan, Ziora, Zyta M., McMillan, Nigel A. J., Monteiro, Michael J. and Toth, Istvan (2014). Synthesis of therapeutic vaccine against cervical cancer. 4th Asia-Pacific International Peptide Symposium in conjunction with 50th Japanese Peptide Symposium, Osaka, Japan, 6-8 November 2013. Osaka, Japan: Japanese Peptide Society.
2014
Other Outputs
Polymers for siRNA delivery
Monteiro, Michael, Gu, W., Phuoc, T. and Jia, Z. (2014). Polymers for siRNA delivery. WO2014015367.
2014
Journal Article
Polymer–peptide hybrids as a highly immunogenic single-dose nanovaccine
Ahmad Fuaad, Abdullah A. H., Jia, Zhongfan, Hartas, Jon, Ziora, Zyta M., Lin, I-Chun, Moyle, Peter M., Batzloff, Michael R., Good, Michael F., Monteiro, Michael J., Skwarczynski, Mariusz and Toth, Istvan (2014). Polymer–peptide hybrids as a highly immunogenic single-dose nanovaccine. Nanomedicine, 9 (1), 35-43. doi: 10.2217/NNM.13.7
2014
Journal Article
Interaction of human arylamine n-acetyltransferase 1 with different nanomaterials
Deng, Zhou J., Butcher, Neville J., Mortimer, Gysell M., Jia, Zhongfan, Monteiro, Michael J., Martin, Darren J. and Minchin, Rodney F. (2014). Interaction of human arylamine n-acetyltransferase 1 with different nanomaterials. Drug Metabolism and Disposition, 42 (3), 377-383. doi: 10.1124/dmd.113.055988
2013
Journal Article
Fine tuning the disassembly time of thermoresponsive polymer nanoparticles
Tran, Nguyen T. D., Jia, Zhongfan, Truong, Nghia P., Cooper, Matthew and Monteiro, Michael J. (2013). Fine tuning the disassembly time of thermoresponsive polymer nanoparticles. Biomacromolecules, 14 (10), 3463-3471. doi: 10.1021/bm4007858
2013
Journal Article
Polymer nanocarrier system for endosome escape and timed release of siRNA with complete gene silencing and cell death in cancer cells
Gu, Wenyi, Jia, Zhongfan, Truong, Nghia P., Prasadam, Indira, Xiao, Yin and Monteiro, Michael J. (2013). Polymer nanocarrier system for endosome escape and timed release of siRNA with complete gene silencing and cell death in cancer cells. Biomacromolecules, 14 (10), 3386-3389. doi: 10.1021/bm401139e
2013
Journal Article
Self-adjuvanting polymer-peptide conjugates as therapeutic vaccine candidates against cervical cancer
Liu, Tzu-Yu, Hussein, Waleed M., Jia, Zhongfan, Ziora, Zyta M., McMillan, Nigel A. J., Monteiro, Michael J., Toth, Istvan and Skwarczynski, Mariusz (2013). Self-adjuvanting polymer-peptide conjugates as therapeutic vaccine candidates against cervical cancer. Biomacromolecules, 14 (8), 2798-2806. doi: 10.1021/bm400626w
2013
Journal Article
An influenza virus-inspired polymer system for the timed release of siRNA
Truong, Nghia P., Gu, Wenyi, Prasadam, Indira, Jia, Zhongfan, Crawford, Ross, Xiao, Yin and Monteiro, Michael J. (2013). An influenza virus-inspired polymer system for the timed release of siRNA. Nature Communications, 4 (1) 1902, 1902. doi: 10.1038/ncomms2905
2013
Journal Article
Plasma protein binding of positively and negatively charged polymer-coated gold nanoparticles elicits different biological responses
Deng, Zhou J., Liang, Mingtao, Toth, Istvan, Monteiro, Michael and Minchin, Rodney F. (2013). Plasma protein binding of positively and negatively charged polymer-coated gold nanoparticles elicits different biological responses. Nanotoxicology, 7 (3), 314-322. doi: 10.3109/17435390.2012.655342
2013
Journal Article
Facile Fabrication of CoreShell-Structured Ag@Carbon and Mesoporous YolkShell-Structured Ag@Carbon@Silica by an Extended Stober Method
Yang, Tianyu, Liu, Jian, Zheng, Yao, Monteiro, Michael J. and Qiao, Shi Zhang (2013). Facile Fabrication of CoreShell-Structured Ag@Carbon and Mesoporous YolkShell-Structured Ag@Carbon@Silica by an Extended Stober Method. Chemistry-A European Journal, 19 (22), 6942-6945. doi: 10.1002/chem.201300523
2013
Journal Article
Thermoresponsive polymer-supported L-proline micelle catalysts for the direct asymmetric aldol reaction in water
Zayas, Hazit A., Lu, Annhelen, Valade, David, Amir, Faheem, Jia, Zhongfan, O'Reilly, Rachel K. and Monteiro, Michael J. (2013). Thermoresponsive polymer-supported L-proline micelle catalysts for the direct asymmetric aldol reaction in water. ACS Macro Letters, 2 (4), 327-331. doi: 10.1021/mz4000943
2013
Journal Article
Laser engineered graphene paper for mass spectrometry imaging
Qian, Kun, Zhou, Liang, Liu, Jian, Yang, Jie, Xu, Hongyi, Yu, Meihua, Nouwens, Amanda, Zou, Jin, Monteiro, Michael J. and Yu, Chengzhong (2013). Laser engineered graphene paper for mass spectrometry imaging. Scientific Reports, 3 (1) 1415, 1415.1-1415.7. doi: 10.1038/srep01415
2013
Journal Article
Timed-release polymer nanoparticles
Nguyen, Tran T. D., Nghia, Truong P., Gu, Wenyi, Jia, Zhongfan, Cooper, Matthew A. and Monteiro, Michael J. (2013). Timed-release polymer nanoparticles. Biomacromolecules, 14 (2), 495-502. doi: 10.1021/bm301721k
2013
Journal Article
Nanofibrillar thermoreversible micellar microgels
Velasco, Diego, Chau, Mokit, Therien-Aubin, Heloise, Kumachev, Alexander, Tumarkin, Ethan, Jia, Zhongfan, Walker, Gilbert C., Monteiro, Michael J. and Kumacheva, Eugenia (2013). Nanofibrillar thermoreversible micellar microgels. Soft Matter, 9 (8), 2380-2383. doi: 10.1039/c2sm27796d
2013
Journal Article
Reversible polymer nanostructures by regulating SDS/PNIPAM binding
Jia, Zhongfan, Truong, Nghia P. and Monteiro, Michael J. (2013). Reversible polymer nanostructures by regulating SDS/PNIPAM binding. Polymer Chemistry, 4 (2), 233-236. doi: 10.1039/c2py20628e
2013
Conference Publication
Various topologies built from tailored cyclic polystyrene via CuAAC/NRC reactions
Monteiro, Michael J. (2013). Various topologies built from tailored cyclic polystyrene via CuAAC/NRC reactions. 245th National Spring Meeting of the American Chemical Society (ACS), New Orleans La, 07-11 April 2013. Washington, DC United States: American Chemical Society.
Funding
Current funding
Past funding
Supervision
Availability
- Professor Michael Monteiro is:
- Available for supervision
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Supervision history
Current supervision
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Doctor Philosophy
Triblock copolymer nanoparticles for anti-cancer delivery
Principal Advisor
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Doctor Philosophy
Synthesis of polymeric vessicles
Principal Advisor
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Doctor Philosophy
Mechanisms of RGD-Functionalized Nanomaterials in Tumor Cell Biology
Principal Advisor
Other advisors: Dr Wenyi Gu, Dr Merja Joensuu
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Doctor Philosophy
Precision-built dynamic and functional polymer dendrimers
Principal Advisor
Completed supervision
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2022
Doctor Philosophy
Topology and Molecular Weight Distribution Control in Polymers
Principal Advisor
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2022
Doctor Philosophy
Synthesis and Self-Assembly of Stimuli-Responsive of Polymer Nanoparticles
Principal Advisor
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2022
Doctor Philosophy
Synthesis of Well-defined Thermoresponsive Polymer Nanostuctures
Principal Advisor
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2019
Doctor Philosophy
Reducing allergic airway inflammation with high-density microprojection array skin patches
Principal Advisor
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2017
Doctor Philosophy
Temperature-Directed Morphology Transformation Method to Produce Well-Defined Complex Multifunctional Polymer Particles
Principal Advisor
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2017
Doctor Philosophy
Synthesis of Well-defined Complex Polymer Architectures by Iterative Growth
Principal Advisor
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2017
Doctor Philosophy
New Insights into Copper-Mediated Polymerization and Polymer Topologies
Principal Advisor
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2015
Doctor Philosophy
Design, Synthesis and Applications of Functional Cabonaceous Nanospheres
Principal Advisor
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2014
Doctor Philosophy
Engineered Polymer Nanoparticles for Intracellular DNA Delivery
Principal Advisor
Other advisors: Professor Peter Gray
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2013
Doctor Philosophy
Development of Ultrafast, Selective and Reversible Nitroxide Radical Coupling Reactions
Principal Advisor
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2013
Doctor Philosophy
Synthesis of Functional Polymers and Nanostructures for siRNA Delivery
Principal Advisor
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2011
Doctor Philosophy
Copper Catalysed Reactions for the Synthesis of Polymeric Architectures
Principal Advisor
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2011
Doctor Philosophy
Synthesis of Complex Polymer Topologies and Their Self-Assembly in Water
Principal Advisor
Other advisors: Professor Joanne Blanchfield
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2009
Doctor Philosophy
New Insights into Diffusion¿Controlled Bimolecular Termination using `Controlled/Living¿ Radical Polymerisation
Principal Advisor
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2021
Doctor Philosophy
Synthesis of Novel Nitroxide Radical Derivatives for Energy Storage and Green Catalyst applications
Associate Advisor
Other advisors: Professor Yusuke Yamauchi
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2018
Doctor Philosophy
Rational Design of Nitroxide Radical Polymers for Enhanced Electrochemical Performance in Rechargeable Batteries
Associate Advisor
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2017
Doctor Philosophy
Understanding the Mechanisms of Transition Metal Catalysed Redox Reactions
Associate Advisor
Other advisors: Professor Paul Bernhardt
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2015
Doctor Philosophy
Development of a Culture Platform for the Expansion of Pluripotent Human Embryonic Stem Cells Cells with the use of Nanopolymers
Associate Advisor
Other advisors: Professor Peter Gray
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2014
Doctor Philosophy
Zinc oxide-centred deterioration of modern artists' oil paint and implications for the conservation of twentieth century paintings
Associate Advisor
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2014
Doctor Philosophy
A Novel Platform Built on Designed Materials for Purification, Enrichment and Detection of Bio-Molecules
Associate Advisor
Other advisors: Dr Wenyi Gu, Professor Michael Yu
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2011
Doctor Philosophy
The Synthesis, Physicochemical Characterization and Biological Interactions of Polymer-coated Nanoparticles
Associate Advisor
Other advisors: Emeritus Professor Istvan Toth
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2010
Doctor Philosophy
Tailored nanoparticles for nanotoxicological investigations
Associate Advisor
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2008
Doctor Philosophy
Synthesis of Nano-scale Polymers via RAFT Polymerization
Associate Advisor
Other advisors: Professor Andrew Whittaker
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2008
Doctor Philosophy
Nanoparticulate Carriers And Adjuvants For Novel Synthetic Peptide Vaccines
Associate Advisor
Other advisors: Emeritus Professor Istvan Toth
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2007
Master Philosophy
SURFACE MODIFICATION USING AMPHIPLILIC DIBLOCK COPOLYMERS FOR TISSUE ENGINEERING APPLICATIONS
Associate Advisor
Other advisors: Professor Justin Cooper-White
Media
Enquiries
Contact Professor Michael Monteiro directly for media enquiries about:
- Dendrimers
- Dendrons
- Drug delivery
- Emulsion polymerisation
- Immunisation - delivery of
- Living radical ploymerisation
- Nanostructures
- Polymer dendrimers
- Polymer nanoparticles
- Polymerisation
- Vaccine delivery
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