Overview
Background
Associate Professor Andy Moore is a Paediatric Oncologist and Director of Research at Children's Health Queensland Hospital & Health Service (CHQ). He is also Director of the Queensland Children's Tumour Bank, a unique resource located on the Queensland Children's Hospital precinct, facilitating local, national and international collaborative research across all childhood cancer types and supporting enrolment of children on clinical trials. A/Prof. Moore's clinical and research interests focus on childhood leukaemia, particularly acute myeloid leukaemia (AML), an aggressive form of leukaemia with a poor prognosis. He also holds a number of leadership and advisory roles, including Deputy Chair of the Australian & New Zealand Childrens Haematology / Oncology Group (ANZCHOG).
Availability
- Dr Andy Moore is:
- Not available for supervision
- Media expert
Fields of research
Qualifications
- Bachelor of Medicine and Surgery and Medical Science, The University of Queensland
- Doctor of Philosophy, University College London
Research interests
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Acute Myeloid Leukaemia
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Leukaemia
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Blood Cancers
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Paediatric Oncology
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Childhood Cancer
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Biobanking
Works
Search Professor Andy Moore’s works on UQ eSpace
2018
Journal Article
Therapy-related acute myeloid leukemia following treatment for cancer in childhood: a population-based registry study
Brown, Catherine A., Youlden, Danny R., Aitken, Joanne F. and Moore, Andrew S. (2018). Therapy-related acute myeloid leukemia following treatment for cancer in childhood: a population-based registry study. Pediatric Blood & Cancer, 65 (12) e27410, e27410. doi: 10.1002/pbc.27410
2018
Conference Publication
Diffuse intrinsic pontine glioma and pediatric glioblastoma derived-exosomes have specific oncogenic signatures
Pericoli, Giulia, Galardi, Angela, Petrilli, Lucia Lisa, Colletti, Marta, Ferretti, Roberta, Paolini, Alessandro, Masotti, Andrea, Mortera, Stefano Levi, Petrini, Stefania, de Billy, Emmanuel, Pascucci, Luisa, Court, Will, Cacchione, Antonella, Carai, Andrea, Camassei, Francesca Diomedi, Moore, Andrew, Carcaboso, Angel Montero, Jones, Chris, Mastronuzzi, Angela, Locatelli, Franco, Di Giannatale, Angela and Vinci, Maria (2018). Diffuse intrinsic pontine glioma and pediatric glioblastoma derived-exosomes have specific oncogenic signatures. 23rd Annual Scientific Meeting and Education Day of the Society-for-Neuro-Oncology (SNO) / 3rd CNS Anticancer Drug Discovery and Development Conference, New Orleans, LA, United States, 14-18 November 2018. Cary, NC, United States: Oxford University Press.
2018
Conference Publication
Targeting H3.3G34R/V re-wiring of the epigenome in paediatric glioblastoma of children and young adults
Bjerke, Lynn, Mackay, Alan, Carvalho, Diana, Pemberton, Helen, Molinari, Valeria, Vinci, Maria, Carceller, Fernando, Marshall, Lynley, Moore, Andrew, Montero Carcaboso, Angel, Lord, Chris, Hargrave, Darren and Jones, Chris (2018). Targeting H3.3G34R/V re-wiring of the epigenome in paediatric glioblastoma of children and young adults. 23rd Annual Scientific Meeting and Education Day of the Society-for-Neuro-Oncology (SNO) / 3rd CNS Anticancer Drug Discovery and Development Conference, New Orleans, United States, 14-18 November, 2018. Cary, NC, United States: Oxford University Press.
2018
Journal Article
The genetic basis and cell of origin of mixed phenotype acute leukaemia
Alexander, Thomas B., Gu, Zhaohui, Iacobucci, Ilaria, Dickerson, Kirsten, Choi, John K., Xu, Beisi, Payne-Turner, Debbie, Yoshihara, Hiroki, Loh, Mignon L., Horan, John, Buldini, Barbara, Basso, Giuseppe, Elitzur, Sarah, de Haas, Valerie, Zwaan, C. Michel, Yeoh, Allen, Reinhardt, Dirk, Tomizawa, Daisuke, Kiyokawa, Nobutaka, Lammens, Tim, De Moerloose, Barbara, Catchpoole, Daniel, Hori, Hiroki, Moorman, Anthony, Moore, Andrew S., Hrusak, Ondrej, Meshinchi, Soheil, Orgel, Etan, Devidas, Meenakshi ... Mullighan, Charles G. (2018). The genetic basis and cell of origin of mixed phenotype acute leukaemia. Nature, 562 (7727), 373-379. doi: 10.1038/s41586-018-0436-0
2018
Journal Article
Functional diversity and cooperativity between subclonal populations of pediatric glioblastoma and diffuse intrinsic pontine glioma cells
Vinci, Mara, Burford, Anna, Molinari, Valeria, Kessler, Ketty, Popov, Sergey, Clarke, Matthew, Taylor, Kathryn R., Pemberton, Helen N., Lord, Christopher J., Gutteridge, Alice, Forshew, Tim, Carvalho, Diana, Marshall, Lynley V., Qin, Elizabeth Y., Ingram, Wendy J., Moore, Andrew S., Ng, Ho-Keung, Trabelsi, Saoussen, H’mida-Ben Brahim, Dorra, Entz-Werle, Natacha, Zacharoulis, Stergios, Vaidya, Sucheta, Mandeville, Henry C., Bridges, Leslie R., Martin, Andrew J., Al-Sarraj, Safa, Chandler, Christopher, Sunol, Mariona, Mora, Jaume ... Jones, Chris (2018). Functional diversity and cooperativity between subclonal populations of pediatric glioblastoma and diffuse intrinsic pontine glioma cells. Nature Medicine, 24 (8), 1204-1215. doi: 10.1038/s41591-018-0086-7
2018
Journal Article
Molecular minimal residual disease monitoring in acute myeloid leukemia: challenges and future directions
Selim, Adrian and Moore, Andrew S (2018). Molecular minimal residual disease monitoring in acute myeloid leukemia: challenges and future directions. The Journal of Molecular Diagnostics, 20 (4), 389-397. doi: 10.1016/j.jmoldx.2018.03.005
2018
Journal Article
Assessing the feasibility and validity of the Toronto Childhood Cancer Stage Guidelines: a population-based registry study
Aitken, Joanne F, Youlden, Danny R, Moore, Andrew S, Baade, Peter D, Ward, Leisa J, Thursfield, Vicky J, Valery, Patricia C, Green, Adèle C, Gupta, Sumit and Frazier, A Lindsay (2018). Assessing the feasibility and validity of the Toronto Childhood Cancer Stage Guidelines: a population-based registry study. The Lancet Child and Adolescent Health, 2 (3), 173-179. doi: 10.1016/S2352-4642(18)30023-3
2018
Journal Article
The MLL recombinome of acute leukemias in 2017
Meyer, C, Burmeister, T, Gröger, D, Tsaur, G, Fechina, L, Renneville, A, Sutton, R, Venn, N C, Emerenciano, M, Pombo-de-Oliveira, M S, Barbieri Blunck, C, Almeida Lopes, B, Zuna, J, Trka, J, Ballerini, P, Lapillonne, H, De Braekeleer, M, Cazzaniga, G, Corral Abascal, L, van der Velden, V H J, Delabesse, E, Park, T S, Oh, S H, Silva, M L M, Lund-Aho, T, Juvonen, V, Moore, A S, Heidenreich, O, Vormoor, J ... Marschalek, R (2018). The MLL recombinome of acute leukemias in 2017. Leukemia, 32 (2), 273-284. doi: 10.1038/leu.2017.213
2018
Journal Article
The ten-year evolutionary trajectory of a highly recurrent paediatric high grade neuroepithelial tumour with MN1:BEND2 fusion
Burford, Anna, Mackay, Alan, Popov, Sergey, Vinci, Maria, Carvalho, Diana, Clarke, Matthew, Izquierdo, Elisa, Avery, Aimee, Jacques, Thomas S., Ingram, Wendy J., Moore, Andrew S., Frawley, Kieran, Hassall, Timothy E., Robertson, Thomas and Jones, Chris (2018). The ten-year evolutionary trajectory of a highly recurrent paediatric high grade neuroepithelial tumour with MN1:BEND2 fusion. Scientific Reports, 8 (1) 1032, 1-10. doi: 10.1038/s41598-018-19389-9
2018
Conference Publication
Aberrant splicing of KMT2A as a potential molecular MRD marker in cytogenetically-normal AML
Zhang, Christine R. C., Afrin, Sadia, Maybury, Mellissa, Pham, Thy, Fink, Lynn and Moore, Andrew S. (2018). Aberrant splicing of KMT2A as a potential molecular MRD marker in cytogenetically-normal AML. 60th Annual Meeting of the American Society of Hematology (ASH), San Diego, CA USA, 1-4 December 2018. Washington, DC USA: American Society of Hematology. doi: 10.1182/blood-2018-99-117759
2018
Conference Publication
The molecular pathology of infant gliomas
Clarke, M., Jones, D. T. W., Carvalho, D., Mackay, A., Izquierdo, E., Hargrave, D., Moore, A. S., Popov, S., Jacques, T. and Jones, C. (2018). The molecular pathology of infant gliomas. 119th Meeting of the British-Neuropathological-Society (BNS) / Epilepsy Neuropathology Symposium, London England, Feb 28-Mar 02 2018. Hoboken, NJ United States: Wiley.
2018
Conference Publication
The Molecular Pathology of Infant Gliomas
Clarke, M. T., Jones, D., Carvalho, D. M., Mackay, A., Izquierdo, E., Hargrave, D., Moore, A. S., Popov, S., Jacques, T. S. and Jones, C. (2018). The Molecular Pathology of Infant Gliomas. Winter Meeting on Epigenetics - Understanding Disease and Guiding Therapies / Joint Meeting of the Royal-Society-of-Medicine / 209th Scientific Meeting of the Pathological-Society-of-Great-Britain-and-Ireland, Marylebone England, 25-26 January 2018. Hoboken, NJ United States: Wiley.
2018
Conference Publication
Quantitative analysis of MLL fusion transcripts by droplet digital PCR to monitor minimal residual disease in MLL-rearranged acute myeloid leukemia
Afrin, Sadia, Zhang, Christine R. C., Meyer, Claus, Maybury, Mellissa, Pham, Thy, Venn, Nicola, Trahair, Toby N., Sutton, Rosemary, Marschalek, Rolf, Fink, Lynn and Moore, Andrew S. (2018). Quantitative analysis of MLL fusion transcripts by droplet digital PCR to monitor minimal residual disease in MLL-rearranged acute myeloid leukemia. 60th Annual Meeting of the American-Society-of-Hematology (ASH), San Diego, CA USA, 1-4 December 2018. Washington, DC USA: American Society of Hematology. doi: 10.1182/blood-2018-99-117761
2017
Journal Article
Development of a targeted sequencing approach to identify prognostic, predictive and diagnostic markers in paediatric solid tumours
Izquierdo, Elisa, Yuan, Lina, George, Sally, Hubank, Michael, Jones, Chris, Proszek, Paula, Shipley, Janet, Gatz, Susanne A., Stinson, Caedyn, Moore, Andrew S., Clifford, Steven C., Hicks, Debbie, Lindsey, Janet C., Hill, Rebecca M., Jacques, Thomas S., Chalker, Jane, Thway, Khin, O'Connor, Simon, Marshall, Lynley, Moreno, Lucas, Pearson, Andrew, Chesler, Louis, Walker, Brian A. and De Castro, David Gonzalez (2017). Development of a targeted sequencing approach to identify prognostic, predictive and diagnostic markers in paediatric solid tumours. Oncotarget, 8 (67), 112036-112050. doi: 10.18632/oncotarget.23000
2017
Journal Article
High prevalence of relapse in children with Philadelphia-like acute lymphoblastic leukemia despite risk-adapted treatment
Heatley, Susan L., Sadras, Teresa, Kok, Chung H., Nievergall, Eva, Quek, Kelly, Dang, Phuong, McClure, Barbara, Venn, Nicola, Moore, Sarah, Suttle, Jeffrey, Law, Tamara, Ng, Anthea, Muskovic, Walter, Norris, Murray D., Revesz, Tamas, Osborn, Michael, Moore, Andrew S., Suppiah, Ram, Fraser, Chris, Alvaro, Frank, Hughes, Timothy P., Mullighan, Charles G., Marshall, Glenn M., Pozza, Luciano Dalla, Yeung, David T., Sutton, Rosemary and White, Deborah L. (2017). High prevalence of relapse in children with Philadelphia-like acute lymphoblastic leukemia despite risk-adapted treatment. Haematologica, 102 (12), 490-493. doi: 10.3324/haematol.2016.162925
2017
Journal Article
Differential expression of MUC4, GPR110 and IL2RA defines two groups of CRLF2-rearranged acute lymphoblastic leukemia patients with distinct secondary lesions
Sadras, Teresa, Heatley, Susan L, Kok, Chung H., Dang, Phuong, Galbraith, Kate M., McClure, Barbara J., Muskovic, Walter, Venn, Nicola C., Moore, Sarah, Osborn, Michael, Revesz, Tamas, Moore, Andrew S., Hughes, Timothy P., Yeung, David, Sutton, Rosemary and White, Deborah L. (2017). Differential expression of MUC4, GPR110 and IL2RA defines two groups of CRLF2-rearranged acute lymphoblastic leukemia patients with distinct secondary lesions. Cancer Letters, 408, 92-101. doi: 10.1016/j.canlet.2017.08.034
2017
Journal Article
Integrated molecular meta-analysis of 1,000 pediatric high-grade and diffuse intrinsic pontine glioma
Mackay, Alan, Burford, Anna, Carvalho, Diana, Izquierdo, Elisa, Fazal-Salom, Janat, Taylor, Kathryn R., Bjerke, Lynn, Clarke, Matthew, Vinci, Mara, Nandhabalan, Meera, Temelso, Sara, Popov, Sergey, Molinari, Valeria, Raman, Pichai, Waanders, Angela J., Han, Harry J., Gupta, Saumya, Marshall, Lynley, Zacharoulis, Stergios, Vaidya, Sucheta, Mandeville, Henry C., Bridges, Leslie R., Martin, Andrew J., Al-Sarraj, Safa, Chandler, Christopher, Ng, Ho-Keung, Li, Xingang, Mu, Kun, Trabelsi, Saoussen ... Jones, Chris (2017). Integrated molecular meta-analysis of 1,000 pediatric high-grade and diffuse intrinsic pontine glioma. Cancer Cell, 32 (4), 520-+. doi: 10.1016/j.ccell.2017.08.017
2017
Journal Article
Erratum to: Population pharmacokinetic modelling of doxorubicin and doxorubicinol in children with cancer: is there a relationship with cardiac troponin profiles? (Cancer Chemotherapy and Pharmacology, (2017), 80, 1, (15-25), 10.1007/s00280-017-3309-6)
Kunarajah, Kuhan, Hennig, Stefanie, Norris, Ross L. G., Lobb, Michael, Charles, Bruce G., Pinkerton, Ross and Moore, Andrew S. (2017). Erratum to: Population pharmacokinetic modelling of doxorubicin and doxorubicinol in children with cancer: is there a relationship with cardiac troponin profiles? (Cancer Chemotherapy and Pharmacology, (2017), 80, 1, (15-25), 10.1007/s00280-017-3309-6). Cancer Chemotherapy and Pharmacology, 80 (1), 27-28. doi: 10.1007/s00280-017-3338-1
2017
Journal Article
Intertumoral heterogeneity within medulloblastoma subgroups
Cavalli, Florence M. G., Remke, Marc, Rampasek, Ladislav, Peacock, John, Shih, David J. H., Luu, Betty, Garzia, Livia, Torchia, Jonathon, Nor, Carolina, Morrissy, A. Sorana, Agnihotri, Sameer, Thompson, Yuan Yao, Kuzan-Fischer, Claudia M., Farooq, Hamza, Isaev, Karen, Daniels, Craig, Cho, Byung-Kyu, Kim, Seung-Kim, Wang, Kyu-Chang, Lee, Ji Yeoun, Grajkowska, Wieslawa A., Perek-Polnik, Marta, Vasiljevic, Alexandre, Faure-Conter, Cecile, Jouvet, Anne, Giannini, Caterina, Nageswara Rao, Anulya A., Li, Kay Ka Wai, Ng, Ho-Keung ... Taylor, Michael D. (2017). Intertumoral heterogeneity within medulloblastoma subgroups. Cancer Cell, 31 (6), 737-754.e6. doi: 10.1016/j.ccell.2017.05.005
2017
Journal Article
Population pharmacokinetic modelling of doxorubicin and doxorubicinol in children with cancer: is there a relationship with cardiac troponin profiles?
Kunarajah, Kuhan, Hennig, Stefanie, Norris, Ross L. G., Lobb, Michael, Charles, Bruce G., Pinkerton, Ross and Moore, Andrew S. (2017). Population pharmacokinetic modelling of doxorubicin and doxorubicinol in children with cancer: is there a relationship with cardiac troponin profiles?. Cancer Chemotherapy and Pharmacology, 80 (1), 15-25. doi: 10.1007/s00280-017-3309-6
Supervision
Availability
- Dr Andy Moore is:
- Not available for supervision
Supervision history
Completed supervision
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2020
Doctor Philosophy
Characterisation of the MLL fusion transcriptome in childhood leukaemia
Principal Advisor
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Doctor Philosophy
Aminopeptidase Inhibition as a Potential Therapeutic Strategy for Acute Myeloid Leukaemia
Principal Advisor
Media
Enquiries
Contact Dr Andy Moore directly for media enquiries about:
- Childhood Cancer
- Childhood Leukaemia
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