
Overview
Background
Dr Zyta Ziora received PhD (Wroclaw University of Science & Technology, Poland) in chemistry and has wide range of experience in development of antimalarial therapeutics (the University of Montpellier, France), antibacterial agents, enzyme inhibitors and drug candidates against Alzheimer disease (Kyoto Pharmaceutical University, Japan). Her research time is currently dedicated mainly to projects devoted to the modification of existing antibiotics, and complexing them with additional antimicrobial agents, like metal ions, to produce more potent alternatives and by this to overcome the drug resistance of superbugs. She is also working on alternative to antibiotics nature-derived compounds with antimicrobial and anticancer potency, such poliphenolic derivatives to control tyrosinase function.
Availability
- Dr Zyta M Ziora is:
- Available for supervision
Fields of research
Qualifications
- Doctor of Philosophy, Wroclaw University of Technology
Research interests
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Researcher and Lecturer in Biotechnology & Molecular Biology Programs
Modification of existing antibiotics – complexing with metal ions Alternative to antibiotics – nature-derived compounds with antimicrobial and anticancer potency Tyrosinase inhibition – potential treatment for skin bacterial infections and melanoma prevention
Research impacts
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Works
Search Professor Zyta M Ziora’s works on UQ eSpace
2021
Journal Article
Sortase A (SrtA) inhibitors as an alternative treatment for superbug infections
Alharthi, Sitah, Ebrahim Alavi, Seyed, Michael Moyle, Peter and Maria Ziora, Zyta (2021). Sortase A (SrtA) inhibitors as an alternative treatment for superbug infections. Drug Discovery Today, 26 (9), 2164-2172. doi: 10.1016/j.drudis.2021.03.019
2021
Journal Article
Formulation and antibacterial activity evaluation of quaternized aminochitosan membrane for wound dressing applications
Omer, Ahmed M., Tamer, Tamer M., Khalifa, Randa E., Eltaweil, Abdelazeem S., Agwa, Mona M., Sabra, Sally, Abd-Elmonem, Mahmoud S., Mohy-Eldin, Mohamed S. and Ziora, Zyta M. (2021). Formulation and antibacterial activity evaluation of quaternized aminochitosan membrane for wound dressing applications. Polymers, 13 (15) 2428, 1-20. doi: 10.3390/polym13152428
2021
Journal Article
ASSURED‐compliant point‐of‐care diagnostics for the detection of human viral infections
Naseri, Mahdi, Ziora, Zyta M., Simon, George P. and Batchelor, Warren (2021). ASSURED‐compliant point‐of‐care diagnostics for the detection of human viral infections. Reviews in Medical Virology, 32 (2) e2263, 1-17. doi: 10.1002/rmv.2263
2021
Journal Article
Bio-potency and molecular docking studies of isolated compounds from Grewia optiva J.R. Drumm. ex Burret
Ul Bari, Wasim, Ur Rehman, Najeeb, Khan, Ajmal, Ahsan Halim, Sobia, Yuan, Ye, Blaskovich, Mark A.T., Ziora, Zyta M., Zahoor, Muhammad, Naz, Sumaira, Ullah, Riaz, Alotaibi, Amal and Al-Harrasi, Ahmed (2021). Bio-potency and molecular docking studies of isolated compounds from Grewia optiva J.R. Drumm. ex Burret. Molecules, 26 (7) 2019, 2019. doi: 10.3390/molecules26072019
2021
Journal Article
Formulation of quaternized aminated chitosan nanoparticles for efficient encapsulation and slow eelease of curcumin
Omer, Ahmed M., Ziora, Zyta M., Tamer, Tamer M., Khalifa, Randa E., Hassan, Mohamed A., Mohy-Eldin, Mohamed S. and Blaskovich, Mark A. T. (2021). Formulation of quaternized aminated chitosan nanoparticles for efficient encapsulation and slow eelease of curcumin. Molecules, 26 (2) 449, 1-14. doi: 10.3390/molecules26020449
2021
Journal Article
Current perspective of innovative strategies for bioremediation of organic pollutants from wastewater
Jain, Marut, Khan, Sadaf Aiman, Sharma, Komal, Jadhao, Prashant Ram, Pant, Kamal Kishore, Ziora, Zyta Maria and Blaskovich, Mark A.T. (2021). Current perspective of innovative strategies for bioremediation of organic pollutants from wastewater. Bioresource Technology, 344 (Pt B) 126305, 126305. doi: 10.1016/j.biortech.2021.126305
2021
Journal Article
Syzygium cumini(L.),Skeels fruit extracts: in vitro and in vivo anti-inflammatory properties
Qamar, Muhammad, Akhtar, Saeed, Ismail, Tariq, Yuan, Ye, Ahmad, Naveed, Tawab, Abdul, Ismail, Amir, Barnard, Ross T., Cooper, Matthew A., Blaskovich, Mark.A.T. and Ziora, Zyta M. (2021). Syzygium cumini(L.),Skeels fruit extracts: in vitro and in vivo anti-inflammatory properties. Journal of Ethnopharmacology, 271 113805, 1-12. doi: 10.1016/j.jep.2021.113805
2020
Journal Article
Hydroxyl substituted benzoic acid/cinnamic acid derivatives: tyrosinase inhibitory kinetics, anti-melanogenic activity and molecular docking studies
Nazir, Yasir, Saeed, Aamer, Rafiq, Muhammad, Afzal, Samina, Ali, Anser, Latif, Muhammad, Zuegg, Johannes, Hussein, Waleed M., Fercher, Christian, Barnard, Ross T., Cooper, Matthew A., Blaskovich, Mark A.T., Ashraf, Zaman and Ziora, Zyta M. (2020). Hydroxyl substituted benzoic acid/cinnamic acid derivatives: tyrosinase inhibitory kinetics, anti-melanogenic activity and molecular docking studies. Bioorganic and Medicinal Chemistry Letters, 30 (1) 126722, 1-5. doi: 10.1016/j.bmcl.2019.126722
2020
Book Chapter
Solid-phase synthesis of octapeptin lipopeptides
Hansford, Karl A., Ziora, Zyta M., Cooper, Matthew A. and Blaskovich, Mark A. T. (2020). Solid-phase synthesis of octapeptin lipopeptides. Peptide synthesis: methods and protocols. (pp. 199-213) edited by Waleed M. Hussein, Mariusz Skwarczynski and Istvan Toth. New York, NY United States: Humana Press. doi: 10.1007/978-1-0716-0227-0_13
2020
Book Chapter
Metal-peptide complexes to study neurodegenerative diseases
Mital, Mariusz, Sęk, Jakub P. and Ziora, Zyta M. (2020). Metal-peptide complexes to study neurodegenerative diseases. Peptide synthesis: methods and protocols. (pp. 323-336) edited by Waleed M. Hussein, Mariusz Skwarczynski and Istvan Toth. New York, NY, United States: Humana Press. doi: 10.1007/978-1-0716-0227-0_22
2020
Book Chapter
Peptidomimetic synthesis: drug discovery for Alzheimer's disease
Hamada, Yoshio and Ziora, Zyta M. (2020). Peptidomimetic synthesis: drug discovery for Alzheimer's disease. Peptide synthesis: methods and protocols. (pp. 215-223) edited by Waleed M. Hussein, Mariusz Skwarczynski and Istvan Toth. New York, NY, United States: Humana Press. doi: 10.1007/978-1-0716-0227-0_14
2019
Journal Article
Non-antibiotic antimicrobial agents to combat biofilm-forming bacteria
Cao, Yuxue, Naseri, Mahdi, He, Yan, Xu, Chun, Walsh, Laurence J. and Ziora, Zyta M. (2019). Non-antibiotic antimicrobial agents to combat biofilm-forming bacteria. Journal of Global Antimicrobial Resistance, 21, 445-451. doi: 10.1016/j.jgar.2019.11.012
2019
Journal Article
Tyrosinase inhibitors as potential antibacterial agents
Yuan, Ye, Jin, Wanli, Nazir, Yasir, Fercher, Christian, Thomas Blaskovich, Mark A., Cooper, Matthew A., Barnard, Ross T. and Ziora, Zyta M. (2019). Tyrosinase inhibitors as potential antibacterial agents. European Journal of Medicinal Chemistry, 187 111892, 111892. doi: 10.1016/j.ejmech.2019.111892
2019
Journal Article
Quinolone antibiotics
Pham, Thu D. M., Ziora, Zyta M. and Blaskovich, Mark A. T. (2019). Quinolone antibiotics. MedChemComm, 10 (10), 1719-1739. doi: 10.1039/c9md00120d
2018
Journal Article
Antimicrobial silver in medicinal and consumer applications: a patent review of the past decade (2007–2017)
Sim, Wilson, Barnard, Ross, Blaskovich, M.A.T. and Ziora, Zyta (2018). Antimicrobial silver in medicinal and consumer applications: a patent review of the past decade (2007–2017). Antibiotics, 7 (4) 93, 93. doi: 10.3390/antibiotics7040093
2018
Journal Article
Silver bullets: a new lustre on an old antimicrobial agent
Möhler, Jasper S., Sim, Wilson, Blaskovich, Mark A. T., Cooper, Matthew A. and Ziora, Zyta M. (2018). Silver bullets: a new lustre on an old antimicrobial agent. Biotechnology Advances, 36 (5), 1391-1411. doi: 10.1016/j.biotechadv.2018.05.004
2018
Journal Article
Wound dressings from naturally-occurring polymers: A review on homopolysaccharide-based composites
Naseri-Nosar, Mahdi and Ziora, Zyta Maria (2018). Wound dressings from naturally-occurring polymers: A review on homopolysaccharide-based composites. Carbohydrate Polymers, 189, 379-398. doi: 10.1016/j.carbpol.2018.02.003
2018
Journal Article
Biological applications of Ru(II) polypyridyl complexes
Mital, Mariusz and Ziora, Zyta (2018). Biological applications of Ru(II) polypyridyl complexes. Coordination Chemistry Reviews, 375, 434-458. doi: 10.1016/j.ccr.2018.02.013
2018
Journal Article
Protein-inspired antibiotics active against vancomycin- and daptomycin-resistant bacteria
Blaskovich, Mark A T, Hansford, Karl A., Gong, Yujing, Butler, Mark S., Muldoon, Craig, Huang, Johnny X., Ramu, Soumya, Silva, Alberto B., Cheng, Mu, Kavanagh, Angela M., Ziora, Zyta, Premraj, Rajaratnam, Lindahl, Fredrik, Bradford, Tanya A., Lee, June C., Karoli, Tomislav, Pelingon, Ruby, Edwards, David J., Amado, Maite, Elliott, Alysha G, Phetsang, Wanida, Daud, Noor Huda, Deecke, Johan E, Sidjabat, Hanna E, Ramaologa, Sefetogi, Zuegg, Johannes, Betley, Jason R, Beevers, Andrew P G, Smith, Richard A G ... Cooper, Matthew A. (2018). Protein-inspired antibiotics active against vancomycin- and daptomycin-resistant bacteria. Nature Communications, 9 (1) 02123, 22. doi: 10.1038/s41467-017-02123-w
2017
Journal Article
Enhancement of antibiotic-activity through complexation with metal ions - Combined ITC, NMR, enzymatic and biological studies
Möhler, Jasper S., Kolmar, Theresa, Synnatschke, Kevin, Hergert, Marcel, Wilson, Liam A., Ramu, Soumya, Elliott, Alysha G., Blaskovich, Mark A.T., Sidjabat, Hanna E., Paterson, David L., Schenk, Gerhard, Cooper, Matthew A. and Ziora, Zyta M. (2017). Enhancement of antibiotic-activity through complexation with metal ions - Combined ITC, NMR, enzymatic and biological studies. Journal of Inorganic Biochemistry, 167, 134-141. doi: 10.1016/j.jinorgbio.2016.11.028
Supervision
Availability
- Dr Zyta M Ziora is:
- Available for supervision
Before you email them, read our advice on how to contact a supervisor.
Available projects
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engineered mesoporous silica nanoparticles loaded with natural bioactive molecules for breast cancer therapy
Silica nanoparticles afford excellent carriers for drug loading and ligand conjugation. This project will design nanoformulations loaded with bioactive molecules. Engineered particles conjugated with ligands/antibodies will achieve high efficacy of nature derived molecules for breast cancer therapy.
Supervision history
Current supervision
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Doctor Philosophy
Development of Biobased Silver Nano-Particles for Application as Wastewater Disinfectant
Principal Advisor
Other advisors: Professor Mark Blaskovich
-
Doctor Philosophy
Synthesis and Physico-chemical characterization of waste derived carbon adsorbents for wastewater treatment
Principal Advisor
Other advisors: Professor Mark Blaskovich
-
Doctor Philosophy
Novel antibiotics containing tyrosinase inhibitors
Associate Advisor
Other advisors: Professor Mark Blaskovich
-
Doctor Philosophy
Engineered mesoporous silica nanoparticles loaded with natural bioactive molecules for breast cancer therapy
Associate Advisor
Other advisors: Associate Professor Peter Moyle
-
Doctor Philosophy
Engineering nanoparticulate anti-virulence compounds for synergy with other antimicrobials
Associate Advisor
Other advisors: Associate Professor Peter Moyle
-
Doctor Philosophy
Bio-evaluation of Human Tyrosinase Inhibitors as Potential Anti-melanoma Agents and Novel Treatment for Parkinson's Disease
Associate Advisor
Other advisors: Professor Mark Blaskovich
-
Doctor Philosophy
Development of Antibacterial Topical Formulations for Post-Production Wine By-Products
Associate Advisor
Other advisors: Dr Harendra Parekh, Dr Anjana Jayasree
-
Doctor Philosophy
ANTIVIRULENCE AGENT NANOFORMULATIONS: A NOVEL STRATEGY TO OVERCOME ANTIBIOTIC RESISTANCE
Associate Advisor
Other advisors: Dr Ben Ross, Professor Amirali Popat, Dr Jared Miles, Associate Professor Jaya Seneviratne, Associate Professor Peter Moyle
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Doctor Philosophy
Engineered mesoporous silica nanoparticles loaded with natural bioactive molecules for breast cancer therapy
Associate Advisor
Other advisors: Associate Professor Peter Moyle
-
Doctor Philosophy
Chemoprevention of Melanoma using natural products and TRAIL- based therapeutics.
Associate Advisor
Other advisors: Professor Brian Gabrielli, Professor Peter Soyer, Associate Professor Helmut Schaider, Dr Jazmina Gonzalez Cruz
-
Doctor Philosophy
Novel topical formulations for the treatment of diseases and infections of the skin
Associate Advisor
Other advisors: Associate Professor Peter Moyle
-
Doctor Philosophy
ANTIVIRULENCE AGENT NANOFORMULATIONS: A NOVEL STRATEGY TO OVERCOME ANTIBIOTIC RESISTANCE
Associate Advisor
Other advisors: Dr Ben Ross, Professor Amirali Popat, Dr Jared Miles, Associate Professor Peter Moyle, Associate Professor Jaya Seneviratne
Completed supervision
-
2024
Doctor Philosophy
Synthesis and Physico-chemical characterization of waste derived carbon adsorbents for wastewater treatment
Principal Advisor
Other advisors: Professor Mark Blaskovich
-
2024
Doctor Philosophy
Development of Biobased Silver Nano-Particles for Application as Wastewater Disinfectant
Principal Advisor
Other advisors: Professor Mark Blaskovich
-
2024
Doctor Philosophy
Expression and Characterisation of Human Tyrosinase as a Target for Novel Inhibitor Development
Associate Advisor
Other advisors: Professor Mark Blaskovich
-
2022
Doctor Philosophy
Naturally Derived Sortase A Inhibitors as an Alternative Treatment for Superbug Infections
Associate Advisor
Other advisors: Associate Professor Peter Moyle
Media
Enquiries
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