
Overview
Background
Dr Zyta Ziora received PhD (Wroclaw University of Science & Technology, Poland) in chemistry and has wide range of experience in development of antimalarial therapeutics (the University of Montpellier, France), antibacterial agents, enzyme inhibitors and drug candidates against Alzheimer disease (Kyoto Pharmaceutical University, Japan). Her research time is currently dedicated mainly to projects devoted to the modification of existing antibiotics, and complexing them with additional antimicrobial agents, like metal ions, to produce more potent alternatives and by this to overcome the drug resistance of superbugs. She is also working on alternative to antibiotics nature-derived compounds with antimicrobial and anticancer potency, such poliphenolic derivatives to control tyrosinase function.
Availability
- Dr Zyta M Ziora is:
- Available for supervision
Fields of research
Qualifications
- Doctor of Philosophy, Wroclaw University of Technology
Research interests
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Researcher and Lecturer in Biotechnology & Molecular Biology Programs
Modification of existing antibiotics – complexing with metal ions Alternative to antibiotics – nature-derived compounds with antimicrobial and anticancer potency Tyrosinase inhibition – potential treatment for skin bacterial infections and melanoma prevention
Research impacts
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Works
Search Professor Zyta M Ziora’s works on UQ eSpace
2023
Journal Article
Sortase A Inhibitor Protein Nanoparticle Formulations Demonstrate Antibacterial Synergy When Combined with Antimicrobial Peptides
Alharthi, Sitah, Popat, Amirali, Ziora, Zyta Maria and Moyle, Peter Michael (2023). Sortase A Inhibitor Protein Nanoparticle Formulations Demonstrate Antibacterial Synergy When Combined with Antimicrobial Peptides. Molecules, 28 (5) 2114, 1-17. doi: 10.3390/molecules28052114
2023
Journal Article
Bioactive peptide discovery from edible insects for potential applications in human health and agriculture
Quah, Yixian, Tong, Shi-Ruo, Bojarska, Joanna, Giller, Katrin, Tan, Sheri-Ann, Ziora, Zyta Maria, Esatbeyoglu, Tuba and Chai, Tsun-Thai (2023). Bioactive peptide discovery from edible insects for potential applications in human health and agriculture. Molecules, 28 (3) 1233, 1-23. doi: 10.3390/molecules28031233
2023
Journal Article
Antioxidant and antibacterial activity of four tannins isolated from different sources and their effect on the shelf-life extension of vacuum-packed minced meat
Nguyen, Chau Ngoc Minh, Nirmal, Nilesh Prakash, Sultanbawa, Yasmina and Ziora, Zyta M. (2023). Antioxidant and antibacterial activity of four tannins isolated from different sources and their effect on the shelf-life extension of vacuum-packed minced meat. Foods, 12 (2) 354, 1-16. doi: 10.3390/foods12020354
2022
Journal Article
Leveraging the potential of silver nanoparticles-based materials towards sustainable water treatment
Khan, Sadaf Aiman, Jain, Marut, Pandey, Ashish, Pant, Kamal Kishore, Ziora, Zyta Maria, Blaskovich, Mark A. T., Shetti, Nagaraj P. and Aminabhavi, Tejraj M. (2022). Leveraging the potential of silver nanoparticles-based materials towards sustainable water treatment. Journal of Environmental Management, 319 115675, 115675. doi: 10.1016/j.jenvman.2022.115675
2022
Journal Article
Antispasmodic activity of the ethanol extract of Citrullus lanatus seeds: justifying ethnomedicinal use in Pakistan to treat asthma and diarrhea
Wahid, Muqeet, Saqib, Fatima, Qamar, Muhammad and Ziora, Zyta M. (2022). Antispasmodic activity of the ethanol extract of Citrullus lanatus seeds: justifying ethnomedicinal use in Pakistan to treat asthma and diarrhea. Journal of Ethnopharmacology, 295 115314, 115314. doi: 10.1016/j.jep.2022.115314
2022
Journal Article
A lipoglycopeptide antibiotic for Gram-positive biofilm-related infections
Blaskovich, Mark A.T., Hansford, Karl A., Butler, Mark S., Ramu, Soumya, Kavanagh, Angela M., Jarrad, Angie M., Prasetyoputri, Anggia, Pitt, Miranda E., Huang, Johnny X., Lindahl, Fredrik, Ziora, Zyta M., Bradford, Tanya, Muldoon, Craig, Rajaratnam, Premraj, Pelingon, Ruby, Edwards, David J., Zhang, Bing, Amado, Maite, Elliott, Alysha G., Zuegg, Johannes, Coin, Lachlan, Woischnig, Anne-Kathrin, Khanna, Nina, Breidenstein, Elena, Stincone, Anna, Mason, Clive, Khan, Nawaz, Cho, Hye-Kyung, Karau, Melissa J. ... Cooper, Matthew A. (2022). A lipoglycopeptide antibiotic for Gram-positive biofilm-related infections. Science Translational Medicine, 14 (662) abj2381. doi: 10.1126/scitranslmed.abj238
2022
Journal Article
A lipoglycopeptide antibiotic for Gram-positive biofilm-related infections
Blaskovich, Mark A.T., Hansford, Karl A., Butler, Mark S., Ramu, Soumya, Kavanagh, Angela M., Jarrad, Angie M., Prasetyoputri, Anggia, Pitt, Miranda E., Huang, Johnny X., Lindahl, Fredrik, Ziora, Zyta M., Bradford, Tanya, Muldoon, Craig, Rajaratnam, Premraj, Pelingon, Ruby, Edwards, David J., Zhang, Bing, Amado, Maite, Elliott, Alysha G., Zuegg, Johannes, Coin, Lachlan, Woischnig, Anne-Kathrin, Khanna, Nina, Breidenstein, Elena, Stincone, Anna, Mason, Clive, Khan, Nawaz, Cho, Hye-Kyung, Karau, Melissa J. ... Cooper, Matthew A. (2022). A lipoglycopeptide antibiotic for Gram-positive biofilm-related infections. Science Translational Medicine, 14 (662) abj2381, 1-16. doi: 10.1126/scitranslmed.abj2381
2022
Journal Article
New Advances in Short Peptides: Looking Forward
Apostolopoulos, Vasso, Bojarska, Joanna, Chai, Tsun-Thai, Feehan, Jack, Kaczmarek, Krzysztof, Matsoukas, John M., Paredes Lopez, Octavio, Saviano, Michele, Skwarczynski, Mariusz, Smith-Carpenter, Jillian, Venanzi, Mariano, Wolf, Wojciech M., Zielenkiewicz, Piotr and Ziora, Zyta M. (2022). New Advances in Short Peptides: Looking Forward. Molecules, 27 (11) 3635, 3635. doi: 10.3390/molecules27113635
2022
Journal Article
Synthesis and characterization of Zinc(II) complex with ONO donor type new phenylpropanehydrazide based ligand: crystal structure, Hirshfeld surface analysis, DFT, energy frameworks and molecular docking
Somashekar, M. N., Chetana, P. R., Chethan, B. S., Rajegowda, H. R., Cooper, M. A., Ziora, Z. M., Lokanath, N. K., Ganapathy, P.S. Sujan and Srinatha, B. S. (2022). Synthesis and characterization of Zinc(II) complex with ONO donor type new phenylpropanehydrazide based ligand: crystal structure, Hirshfeld surface analysis, DFT, energy frameworks and molecular docking. Journal of Molecular Structure, 1255 132429, 132429. doi: 10.1016/j.molstruc.2022.132429
2022
Journal Article
Formulation and biological evaluation of mesoporous silica nanoparticles loaded with combinations of sortase A inhibitors and antimicrobial peptides
Alharthi, Sitah, Ziora, Zyta M., Janjua, Taskeen, Popat, Amirali and Moyle, Peter M. (2022). Formulation and biological evaluation of mesoporous silica nanoparticles loaded with combinations of sortase A inhibitors and antimicrobial peptides. Pharmaceutics, 14 (5) 986, 986. doi: 10.3390/pharmaceutics14050986
2022
Journal Article
Statistical evaluation of cow-dung derived activated biochar for phenol adsorption: adsorption isotherms, kinetics, and thermodynamic studies
Jain, Marut, Khan, Sadaf Aiman, Sahoo, Abhisek, Dubey, Prashant, Pant, Kamal Kishore, Ziora, Zyta Maria and Blaskovich, Mark A.T. (2022). Statistical evaluation of cow-dung derived activated biochar for phenol adsorption: adsorption isotherms, kinetics, and thermodynamic studies. Bioresource Technology, 352 127030, 127030. doi: 10.1016/j.biortech.2022.127030
2022
Journal Article
Syzygium cumini (L.) Skeels extracts; in vivo anti-nociceptive, anti-inflammatory, acute and subacute toxicity assessment
Qamar, Muhammad, Akhtar, Saeed, Ismail, Tariq, Wahid, Muqeet, Ali, Sajed, Nazir, Yasir, Murtaza, Shahid, Abbas, Malik Waseem and Ziora, Zyta M. (2022). Syzygium cumini (L.) Skeels extracts; in vivo anti-nociceptive, anti-inflammatory, acute and subacute toxicity assessment. Journal of Ethnopharmacology, 287 114919, 114919. doi: 10.1016/j.jep.2021.114919
2022
Journal Article
Antiinflammatory and anticancer properties of Grewia asiatica crude extracts and fractions: a bioassay-guided approach
Qamar, Muhammad, Akhtar, Saeed, Barnard, Ross T., Sestili, Piero, Ziora, Zyta M., Lazarte, Claudia E. and Ismail, Tariq (2022). Antiinflammatory and anticancer properties of Grewia asiatica crude extracts and fractions: a bioassay-guided approach. BioMed Research International, 2022 (1) 2277417, 1-14. doi: 10.1155/2022/2277417
2022
Journal Article
Antimicrobial activity enhancers: towards smart delivery of antimicrobial agents
Skwarczynski, Mariusz, Bashiri, Sahra, Yuan, Ye, Ziora, Zyta M., Nabil, Osama, Masuda, Keita, Khongkow, Mattaka, Rimsueb, Natchanon, Cabral, Horacio, Ruktanonchai, Uracha, Blaskovich, Mark A. T. and Toth, Istvan (2022). Antimicrobial activity enhancers: towards smart delivery of antimicrobial agents. Antibiotics, 11 (3) 412, 412. doi: 10.3390/antibiotics11030412
2022
Journal Article
Insights into recent advances of chitosan-based adsorbents for sustainable removal of heavy metals and anions
Omer, Ahmed M., Dey, Rana, Eltaweil, Abdelazeem S., Abd El-Monaem, Eman M. and Ziora, Zyta M. (2022). Insights into recent advances of chitosan-based adsorbents for sustainable removal of heavy metals and anions. Arabian Journal of Chemistry, 15 (2) 103543, 103543. doi: 10.1016/j.arabjc.2021.103543
2022
Journal Article
Phytochemical profile, biological properties, and food applications of the medicinal plant Syzygium cumini
Qamar, Muhammad, Akhtar, Saeed, Ismail, Tariq, Wahid, Muqeet, Abbas, Malik Waseem, Mubarak, Mohammad S., Yuan, Ye, Barnard, Ross T., Ziora, Zyta M. and Esatbeyoglu, Tuba (2022). Phytochemical profile, biological properties, and food applications of the medicinal plant Syzygium cumini. Foods, 11 (3) 378, 378. doi: 10.3390/foods11030378
2021
Journal Article
The chemical composition and health-promoting effects of the Grewia species—a systematic review and meta-analysis
Qamar, Muhammad, Akhtar, Saeed, Ismail, Tariq, Wahid, Muqeet, Barnard, Ross T., Esatbeyoglu, Tuba and Ziora, Zyta M. (2021). The chemical composition and health-promoting effects of the Grewia species—a systematic review and meta-analysis. Nutrients, 13 (12) 4565, 4565. doi: 10.3390/nu13124565
2021
Journal Article
Optimized protocols for assessing libraries of poorly soluble sortase A inhibitors for antibacterial activity against medically-relevant bacteria, toxicity and enzyme inhibition
Alharthi, Sitah, Ziora, Zyta Maria and Moyle, Peter Michael (2021). Optimized protocols for assessing libraries of poorly soluble sortase A inhibitors for antibacterial activity against medically-relevant bacteria, toxicity and enzyme inhibition. Bioorganic and Medicinal Chemistry, 52 116527, 116527. doi: 10.1016/j.bmc.2021.116527
2021
Journal Article
Instructive analysis of engineered carbon materials for potential application in water and wastewater treatment
Jain, Marut, Khan, Sadaf Aiman, Pandey, Ashish, Pant, Kamal Kishore, Ziora, Zyta Maria and Blaskovich, Mark A.T. (2021). Instructive analysis of engineered carbon materials for potential application in water and wastewater treatment. Science of The Total Environment, 793 148583, 1-19. doi: 10.1016/j.scitotenv.2021.148583
2021
Journal Article
Cyclic dipeptides: the biological and structural landscape with special focus on the anti-cancer proline-based scaffold
Bojarska, Joanna, Mieczkowski, Adam, Ziora, Zyta, Skwarczynski, Mariusz, Toth, Istvan, Shalash, Ahmed O., Parang, Keykavous, El-Mowafi, Shaima A., Mohammed, Eman H. M., Elnagdy, Sherif, AlKhazindar, Maha and Wolf, Wojciech M. (2021). Cyclic dipeptides: the biological and structural landscape with special focus on the anti-cancer proline-based scaffold. Biomolecules, 11 (10) 1515, 1515. doi: 10.3390/biom11101515
Supervision
Availability
- Dr Zyta M Ziora is:
- Available for supervision
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Available projects
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engineered mesoporous silica nanoparticles loaded with natural bioactive molecules for breast cancer therapy
Silica nanoparticles afford excellent carriers for drug loading and ligand conjugation. This project will design nanoformulations loaded with bioactive molecules. Engineered particles conjugated with ligands/antibodies will achieve high efficacy of nature derived molecules for breast cancer therapy.
Supervision history
Current supervision
-
Doctor Philosophy
Synthesis and Physico-chemical characterization of waste derived carbon adsorbents for wastewater treatment
Principal Advisor
Other advisors: Professor Mark Blaskovich
-
Doctor Philosophy
Development of Biobased Silver Nano-Particles for Application as Wastewater Disinfectant
Principal Advisor
Other advisors: Professor Mark Blaskovich
-
Doctor Philosophy
Chemoprevention of Melanoma using natural products and TRAIL- based therapeutics.
Associate Advisor
Other advisors: Professor Brian Gabrielli, Professor Peter Soyer, Associate Professor Helmut Schaider, Dr Jazmina Gonzalez Cruz
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Doctor Philosophy
Novel topical formulations for the treatment of diseases and infections of the skin
Associate Advisor
Other advisors: Associate Professor Peter Moyle
-
Doctor Philosophy
ANTIVIRULENCE AGENT NANOFORMULATIONS: A NOVEL STRATEGY TO OVERCOME ANTIBIOTIC RESISTANCE
Associate Advisor
Other advisors: Dr Ben Ross, Professor Amirali Popat, Dr Jared Miles, Associate Professor Peter Moyle, Associate Professor Jaya Seneviratne
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Doctor Philosophy
Novel antibiotics containing tyrosinase inhibitors
Associate Advisor
Other advisors: Professor Mark Blaskovich
-
Doctor Philosophy
Engineered mesoporous silica nanoparticles loaded with natural bioactive molecules for breast cancer therapy
Associate Advisor
Other advisors: Associate Professor Peter Moyle
-
Doctor Philosophy
Engineering nanoparticulate anti-virulence compounds for synergy with other antimicrobials
Associate Advisor
Other advisors: Associate Professor Peter Moyle
-
Doctor Philosophy
Bio-evaluation of Human Tyrosinase Inhibitors as Potential Anti-melanoma Agents and Novel Treatment for Parkinson's Disease
Associate Advisor
Other advisors: Professor Mark Blaskovich
-
Doctor Philosophy
Development of Antibacterial Topical Formulations for Post-Production Wine By-Products
Associate Advisor
Other advisors: Dr Harendra Parekh, Dr Anjana Jayasree
-
Doctor Philosophy
ANTIVIRULENCE AGENT NANOFORMULATIONS: A NOVEL STRATEGY TO OVERCOME ANTIBIOTIC RESISTANCE
Associate Advisor
Other advisors: Dr Ben Ross, Professor Amirali Popat, Dr Jared Miles, Associate Professor Jaya Seneviratne, Associate Professor Peter Moyle
-
Doctor Philosophy
Engineered mesoporous silica nanoparticles loaded with natural bioactive molecules for breast cancer therapy
Associate Advisor
Other advisors: Associate Professor Peter Moyle
Completed supervision
-
2024
Doctor Philosophy
Synthesis and Physico-chemical characterization of waste derived carbon adsorbents for wastewater treatment
Principal Advisor
Other advisors: Professor Mark Blaskovich
-
2024
Doctor Philosophy
Development of Biobased Silver Nano-Particles for Application as Wastewater Disinfectant
Principal Advisor
Other advisors: Professor Mark Blaskovich
-
2024
Doctor Philosophy
Expression and Characterisation of Human Tyrosinase as a Target for Novel Inhibitor Development
Associate Advisor
Other advisors: Professor Mark Blaskovich
-
2022
Doctor Philosophy
Naturally Derived Sortase A Inhibitors as an Alternative Treatment for Superbug Infections
Associate Advisor
Other advisors: Associate Professor Peter Moyle
Media
Enquiries
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