Dr Zyta M Ziora
Dr

Zyta M Ziora

Email: 
Phone: 
+61 7 334 62202

Background

Dr Zyta Ziora received PhD (Wroclaw University of Science & Technology, Poland) in chemistry and has wide range of experience in development of antimalarial therapeutics (the University of Montpellier, France), antibacterial agents, enzyme inhibitors and drug candidates against Alzheimer disease (Kyoto Pharmaceutical University, Japan). Her research time is currently dedicated mainly to projects devoted to the modification of existing antibiotics, and complexing them with additional antimicrobial agents, like metal ions, to produce more potent alternatives and by this to overcome the drug resistance of superbugs. She is also working on alternative to antibiotics nature-derived compounds with antimicrobial and anticancer potency, such poliphenolic derivatives to control tyrosinase function.

Availability

Dr Zyta M Ziora is:
Available for supervision

Fields of research

Medicinal and biomolecular chemistry Organic chemistry Pharmacology and pharmaceutical sciences

Qualifications

  • Doctor of Philosophy, Wroclaw University of Technology

Research interests

  • Researcher and Lecturer in Biotechnology & Molecular Biology Programs

    Modification of existing antibiotics – complexing with metal ions Alternative to antibiotics – nature-derived compounds with antimicrobial and anticancer potency Tyrosinase inhibition – potential treatment for skin bacterial infections and melanoma prevention

Research impacts

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Search Professor Zyta M Ziora’s works on UQ eSpace

101 works between 1999 and 2025
All (101) Journal Article (89) Book Chapter (7) Conference Publication (5)

61 - 80 of 101 works

2016

Journal Article

Short cationic lipopeptides as effective antibacterial agents: design, physicochemical properties and biological evaluation

Azmi, Fazren, Elliott, Alysha G., Marasini, Nirmal, Ramu, Soumya, Ziora, Zyta, Kavanagh, Angela M., Blaskovich, Mark A. T., Cooper, Matthew A., Skwarczynski, Mariusz and Toth, Istvan (2016). Short cationic lipopeptides as effective antibacterial agents: design, physicochemical properties and biological evaluation. Bioorganic and Medicinal Chemistry, 24 (10), 2235-2241. doi: 10.1016/j.bmc.2016.03.053

Short cationic lipopeptides as effective antibacterial agents: design, physicochemical properties and biological evaluation

2016

Journal Article

Platinum-based anticancer drugs encapsulated liposome and polymeric micelle formulation in clinical trials

Hang, Zhou, Cooper, Matthew A. and Ziora, Zyta M. (2016). Platinum-based anticancer drugs encapsulated liposome and polymeric micelle formulation in clinical trials. Biochemical Compounds, 4. doi: 10.7243/2052-9341-4-2

Platinum-based anticancer drugs encapsulated liposome and polymeric micelle formulation in clinical trials

2015

Journal Article

Ethanol concentration influences the mechanisms of wine tannin interactions with poly(l -proline) in model wine

McRae, Jacqui M., Ziora, Zyta M., Kassara, Stella, Cooper, Matthew A. and Smith, Paul A. (2015). Ethanol concentration influences the mechanisms of wine tannin interactions with poly(l -proline) in model wine. Journal of Agricultural and Food Chemistry, 63 (17), 4345-4352. doi: 10.1021/acs.jafc.5b00758

Ethanol concentration influences the mechanisms of wine tannin interactions with poly(l -proline) in model wine

2014

Journal Article

Anti-cooperative ligand binding and dimerisation in the glycopeptide antibiotic dalbavancin

Cheng, Mu, Ziora, Zyta M., Hansford, Karl A., Blaskovich, Mark A., Butler, Mark S. and Cooper, Matthew A. (2014). Anti-cooperative ligand binding and dimerisation in the glycopeptide antibiotic dalbavancin. Organic and Biomolecular Chemistry, 12 (16), 2568-2575. doi: 10.1039/c3ob42428f

Anti-cooperative ligand binding and dimerisation in the glycopeptide antibiotic dalbavancin

2014

Journal Article

Ovalbumin lipid core peptide vaccines and their CD4+ and CD8+ T cell responses

Simerska, Pavla, Suksamran, Tittaya, Ziora, Zyta Maria, Rivera, Fabian de Labastida, Engwerda, Christian and Toth, Istvan (2014). Ovalbumin lipid core peptide vaccines and their CD4+ and CD8+ T cell responses. Vaccine, 32 (37), 4743-4750. doi: 10.1016/j.vaccine.2014.06.049

Ovalbumin lipid core peptide vaccines and their CD4+ and CD8+ T cell responses

2014

Journal Article

Polymer–peptide hybrids as a highly immunogenic single-dose nanovaccine

Ahmad Fuaad, Abdullah A. H., Jia, Zhongfan, Hartas, Jon, Ziora, Zyta M., Lin, I-Chun, Moyle, Peter M., Batzloff, Michael R., Good, Michael F., Monteiro, Michael J., Skwarczynski, Mariusz and Toth, Istvan (2014). Polymer–peptide hybrids as a highly immunogenic single-dose nanovaccine. Nanomedicine, 9 (1), 35-43. doi: 10.2217/NNM.13.7

Polymer–peptide hybrids as a highly immunogenic single-dose nanovaccine

2014

Conference Publication

Synthesis of therapeutic vaccine against cervical cancer

Skwarczynski, Mariusz, Liu, Tzu-Yu, Hussein, Waleed M., Jia, Zhongfan, Ziora, Zyta M., McMillan, Nigel A. J., Monteiro, Michael J. and Toth, Istvan (2014). Synthesis of therapeutic vaccine against cervical cancer. 4th Asia-Pacific International Peptide Symposium in conjunction with 50th Japanese Peptide Symposium, Osaka, Japan, 6-8 November 2013. Osaka, Japan: Japanese Peptide Society.

Synthesis of therapeutic vaccine against cervical cancer

2013

Journal Article

ChemInform abstract: lipoamino acids as major components of absorption promoters in drug delivery

Ziora, Zyta M., Blaskovich, Mark A., Toth, Istvan and Cooper, Matthew A. (2013). ChemInform abstract: lipoamino acids as major components of absorption promoters in drug delivery. ChemInform, 44 (43), no-no. doi: 10.1002/chin.201343267

ChemInform abstract: lipoamino acids as major components of absorption promoters in drug delivery

2013

Journal Article

Design, synthesis and characterisation of mannosylated ovalbumin lipid core peptide self-adjuvanting vaccine delivery system

Simerska, Pavla, Ziora, Zyta Maria, Fagan, Vincent, Goodwin, Daryn, Edrous, Farrah and Toth, Istvan (2013). Design, synthesis and characterisation of mannosylated ovalbumin lipid core peptide self-adjuvanting vaccine delivery system. Drug Delivery and Translational Research, Online First (3), 1-10. doi: 10.1007/s13346-013-0173-8

Design, synthesis and characterisation of mannosylated ovalbumin lipid core peptide self-adjuvanting vaccine delivery system

2013

Journal Article

Self-adjuvanting polymer-peptide conjugates as therapeutic vaccine candidates against cervical cancer

Liu, Tzu-Yu, Hussein, Waleed M., Jia, Zhongfan, Ziora, Zyta M., McMillan, Nigel A. J., Monteiro, Michael J., Toth, Istvan and Skwarczynski, Mariusz (2013). Self-adjuvanting polymer-peptide conjugates as therapeutic vaccine candidates against cervical cancer. Biomacromolecules, 14 (8), 2798-2806. doi: 10.1021/bm400626w

Self-adjuvanting polymer-peptide conjugates as therapeutic vaccine candidates against cervical cancer

2013

Journal Article

pH-Triggered peptide self-assembly into fibrils: a potential peptide-based subunit vaccine delivery platform

Skwarczynski, Mariusz, Kowapradit, Jariya, Ziora, Zyta Maria and Toth, Istvan (2013). pH-Triggered peptide self-assembly into fibrils: a potential peptide-based subunit vaccine delivery platform. Biochemical Compounds, 1. doi: 10.7243/2052-9341-1-2

pH-Triggered peptide self-assembly into fibrils: a potential peptide-based subunit vaccine delivery platform

2012

Journal Article

Structure-activity relationship for the development of a self-adjuvanting mucosally active lipopeptide vaccine against Streptococcus pyogenes

Zaman, Mehfuz, Abdel-Aal, Abu-Baker M., Fujita, Yoshio, Ziora, Zyta M., Batzloff, Michael R., Good, Michael F. and Toth, Istvan (2012). Structure-activity relationship for the development of a self-adjuvanting mucosally active lipopeptide vaccine against Streptococcus pyogenes. Journal of Medicinal Chemistry, 55 (19), 8515-8523. doi: 10.1021/jm301074n

Structure-activity relationship for the development of a self-adjuvanting mucosally active lipopeptide vaccine against Streptococcus pyogenes

2012

Journal Article

Lipoamino acids as major components of absorption promoters in drug delivery

Ziora, Zyta M., Blaskovich, Mark A., Toth, Istvan and Cooper, Matthew A. (2012). Lipoamino acids as major components of absorption promoters in drug delivery. Current Topics in Medicinal Chemistry, 12 (14), 1562-1580. doi: 10.2174/156802612802652448

Lipoamino acids as major components of absorption promoters in drug delivery

2012

Journal Article

ChemInform Abstract: Medicinal Chemistry of α-Hydroxy-β-amino Acids

Ziora, Zyta, Skwarczynski, Mariusz and Kiso, Yoshiaki (2012). ChemInform Abstract: Medicinal Chemistry of α-Hydroxy-β-amino Acids. ChemInform, 43 (25), no-no. doi: 10.1002/chin.201225259

ChemInform Abstract: Medicinal Chemistry of α-Hydroxy-β-amino Acids

2012

Journal Article

Lipopeptides for the fragment-based pharmaceutics design

Ziora, Zyta M., Wimmer, Norbert, New, Roger, Skwarczynski, Mariusz and Toth, Istvan (2012). Lipopeptides for the fragment-based pharmaceutics design. International Journal of Organic Chemistry, 2 (01), 75-81. doi: 10.4236/ijoc.2012.21013

Lipopeptides for the fragment-based pharmaceutics design

2012

Conference Publication

New glycopeptidic antibiotics to combat multidrug resistant pathogens

Gong, Y., Muldoon, C. A., Premraj, R., Ziora, Z. M., Bradford, T. A., Cheng, M., Ramu, S., Huang, J. X., Kavanagh, A., Pelingon, R., Lee, J. C., Wong, K., Butler, M. S., Blaskovich, M. A. and Cooper, M. A. (2012). New glycopeptidic antibiotics to combat multidrug resistant pathogens. 32nd European Peptide Symposium, Athens, Greece, 2-7 September 2012. Chichester, West Sussex, United Kingdom: John Wiley & Sons. doi: 10.1002/psc.2449

New glycopeptidic antibiotics to combat multidrug resistant pathogens

2012

Conference Publication

Nanoparticles-based peptide subunit vaccines against group A Streptococcus

Skwarczynski, M., Fuaad, A. A. H. A., Zaman, M., Jia, Z., Kowapradit, J., Rustanti, L., Ziora, Z. M., Monteiro, M. L. J., Batzloff, M. R., Goodc, M. F. and Toth, I. (2012). Nanoparticles-based peptide subunit vaccines against group A Streptococcus. 32nd European Peptide Symposium, Athens, Greece, 2-7 September 2012. Chichester, West Sussex, United Kingdom: John Wiley & Sons. doi: 10.1002/psc.2448

Nanoparticles-based peptide subunit vaccines against group A Streptococcus

2011

Journal Article

Synthesis of glycolipopeptidic building blocks for carbohydrate receptor discovery

Ziora, Zyta M., Wimmer, Norbert, New, Roger, Skwarczynski, Mariusz and Toth, Istvan (2011). Synthesis of glycolipopeptidic building blocks for carbohydrate receptor discovery. Carbohydrate Research, 346 (12), 1439-1444. doi: 10.1016/j.carres.2011.03.019

Synthesis of glycolipopeptidic building blocks for carbohydrate receptor discovery

2011

Journal Article

Interaction of densely polymer-coated gold nanoparticles with epithelial Caco-2 monolayers

Lin, I-Chun, Liang, Mingtao, Liu, Tzu-Yu, Ziora, Zyta M., Monteiro, Michael J. and Toth, Istvan (2011). Interaction of densely polymer-coated gold nanoparticles with epithelial Caco-2 monolayers. Biomacromolecules, 12 (4), 1339-1348. doi: 10.1021/bm200116z

Interaction of densely polymer-coated gold nanoparticles with epithelial Caco-2 monolayers

2011

Journal Article

Group A streptococcal vaccine candidates based on the conserved conformational epitope from M protein

Skwarczynski, Mariusz, Ahmad Fuaad, Abdullah A. H., Rustanti, Lina, Ziora, Zyta M., Aqil, Mohammed, Batzloff, Michael R., Good, Michael F. and Toth, Istvan (2011). Group A streptococcal vaccine candidates based on the conserved conformational epitope from M protein. Drug Delivery Letters, 1 (1), 2-8. doi: 10.2174/2210304X11101010002

Group A streptococcal vaccine candidates based on the conserved conformational epitope from M protein

Current funding

  • 2023 - 2028
    ARC Training Centre for Environmental and Agricultural Solutions to Antimicrobial Resistance (ARC CEA-StAR)
    ARC Industrial Transformation Training Centres
    Open grant

Past funding

  • 2017 - 2018
    Natureceuticals from post-production wine extracts
    Innovation Connections
    Open grant

Availability

Dr Zyta M Ziora is:
Available for supervision

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Available projects

Supervision history

Current supervision

Completed supervision

Enquiries

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