Overview
Background
BSc in Biology (1988) Umea University, Sweden
PhD in Molecular Biology (1994), Umea University, Sweden. Supervisor: Thomas Edlund
Postdoc, Molecular Neurobiology (1994-1999) Salk Institute, La Jolla, USA. Mentor: John B. Thomas
Assistant Professor (1999-2004), Harvard Medical School, Boston, USA
Professor of Developmental Biology (2004-2019), Linkoping University, Sweden
Professor of Developmental Biology (2019-), University of Queensland, Brisbane, Australia
Member of the Royal Swedish Academy of Sciences (2013-)
Member of ARC Collegeof Experts (2025-2027)
Availability
- Professor Stefan Thor is:
- Available for supervision
Qualifications
- Doctor of Philosophy, Institution to be confirmed
Works
Search Professor Stefan Thor’s works on UQ eSpace
1989
Conference Publication
Cis- and transacting elements regulating insulin gene transcription
Ohlsson, H., Karlsson, O., Norberg, T., Thor, S. and Edlund, T. (1989). Cis- and transacting elements regulating insulin gene transcription. Elsevier Science Publishers B.V..
Supervision
Availability
- Professor Stefan Thor is:
- Available for supervision
Looking for a supervisor? Read our advice on how to choose a supervisor.
Available projects
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The role of the hypothalamic neuropeptide Npvf in mouse fertility and sleep-wake behaviours
The hypothalamic neuropeptide Npvf is expressed by a very small subset of neurons within the hypothalamus. Npvf has been implicated in fertility, seasonal mating behaviour and sleep-wake behaviours, in several different mammalian species, as well as in the zebrafish. But these studies have been based upon correlative experiments, RNAi and peptide injections, and the Npvf gene has hitherto not beek knocked out. we have geneerated a condititional null allele of Npvf. This project aims to address the effect of a null mutation in Npvf upon a set of mouse behaviours.
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The role of the mouse Tead1/Vgll2 transcription factors in dictating hypothalamic cell fate
The hypothalamic neuropeptide Npvf is expressed by a very small subset of neurons within the hypothalamus. Npvf has been implicated in fertility, seasonal mating behaviour and sleep-wake behaviours. Using single cell transcriptional profiling, we and others have identified the transcription factors Tead1 and Vgll2 as selectively expressed in Npvf neurons in the mouse hypothalamus. The Tead and Vgll families typically interact and form a complex. We have generated a mouse Tead1 knock-out, and found that the Npvf neurons are missing. The project aims to address the underlying reason for the phenotype. We are also in the process of obtaining the mouse Vgll2 knockout, to be able to compare the effects of this knock-out with that of Tead1.
Supervision history
Current supervision
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Doctor Philosophy
Developing an in vitro human sleep system
Principal Advisor
Other advisors: Professor Michael Piper, Professor Ernst Wolvetang
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Doctor Philosophy
Generating complex brain organoids from human stem cells
Principal Advisor
Other advisors: Professor Michael Piper, Professor Ernst Wolvetang
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Doctor Philosophy
Decoding the generation of mouse and human HCRT and NPVF hypothalamic sleep neurons
Principal Advisor
Other advisors: Professor Michael Piper, Professor Ernst Wolvetang
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Doctor Philosophy
Elucidating the role of Human Aminoacyl multi- tRNA synthetase complex (MSC) in Hypomyelination with brainstem and spinal cord involvement and leg spasticity (HBSL)
Associate Advisor
Other advisors: Professor Jessica Mar, Professor Ernst Wolvetang
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Doctor Philosophy
The histone methyltransferase NSD1 regulates the development of the mouse telencephalon
Associate Advisor
Other advisors: Professor Michael Piper
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Doctor Philosophy
How SETD2 shapes cortical development
Associate Advisor
Other advisors: Professor Mikael Boden, Professor Michael Piper
Completed supervision
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2026
Doctor Philosophy
Cell state changes during metamorphosis in the marine sponge Amphimedon queenslandica
Associate Advisor
Other advisors: Professor Sandie Degnan, Professor Bernard Degnan
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2023
Doctor Philosophy
The role of the Polycomb protein Eed in the mouse cerebral cortex
Associate Advisor
Other advisors: Professor Michael Piper
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2023
Doctor Philosophy
Cell Type Definition from Single Cell RNA-seq
Associate Advisor
Other advisors: Professor Michael Piper, Professor Jessica Mar, Professor Mikael Boden
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2023
Doctor Philosophy
Machine learning models of epigenetic dynamics driving cell fate
Associate Advisor
Other advisors: Professor Jessica Mar, Professor Mikael Boden
Media
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