Associate Professor Jane Nikles
Associate Professor

Jane Nikles

Email: 

Background

I am a registered medical practitioner with a PhD from The University of Queensland. My doctoral work was in the field of population health, and focused on the use of N-of-1 trial methodology in clinical practice. I have two major research areas: N-of-1 trials/Single Case Experimental Designs (SCEDs), and whiplash and other musculoskeletal pain after Road Traffic Crashes.

I played a key role in setting up and sustaining UQ’s N-of-1 trials Unit since 1998, and am a key driver of its success, resulting in UQ becoming a world leader in N-of-1 trials since 2009. . Building on my 20 year clinical research career at UQ, I lead the research program at UQCCR in N-of-1 trials, and am a recognised leader in this field both in Australia and internationally. In addition, my skills include trial design and management more broadly.

I am also working at Recover Injury Research Centre in the field of recovery following Road Traffic injuries. Within the Designing Better Therapies research program, my main focus is on improving early management and reducing opioid prescribing for minor musculoskeletal injuries after Road Traffic Crashes. My other area of research is in applying Single Case Experimental Designs to work towards better therapies after injury, especially when caused by Road Traffic Crashes.

Availability

Associate Professor Jane Nikles is:
Available for supervision
Media expert

Qualifications

  • Bachelor of Medicine and Surgery and Medical Science, The University of Queensland
  • Doctor of Philosophy, The University of Queensland

Research interests

  • Clinical trials, n-of-1 trials, research methodology, personalised medicine, individual treatments

  • Single Case Experimental Designs

  • Whiplash, minor musculoskeletal injury, opioid prescribing

  • ADHD, children, sleep

  • Melatonin

  • Parkinson's Disease

  • Skin cancer prevention, improving children's sun protection practices

Search Professor Jane Nikles’s works on UQ eSpace

188 works between 1983 and 2026
All (188) Book (3) Journal Article (86) Other Outputs (4) Conference Publication (89) Book Chapter (6)

81 - 100 of 188 works

2018

Conference Publication

N-of-1 trials in the clinical care of patients in developing countries: a systematic review

Alemayehu, C., Mitchell, G. and Nikles, J. (2018). N-of-1 trials in the clinical care of patients in developing countries: a systematic review. 6th International Conference on Advanced Clinical Research and Clinical Trials, Zurich, Switzerland, 2018.

N-of-1 trials in the clinical care of patients in developing countries: a systematic review

2018

Conference Publication

N-of-1 therapeutic equivalence trial of two formulations of Enalapril in the treatment of hypertension in Ethiopia - Pilot study

Alemayehu, C., Mitchell, G., Aseffa, A., Clavarino, A., McGree, J. and Nikles, J. (2018). N-of-1 therapeutic equivalence trial of two formulations of Enalapril in the treatment of hypertension in Ethiopia - Pilot study. Translational Research Institute, Brisbane, QLD, Australia, 2018.

N-of-1 therapeutic equivalence trial of two formulations of Enalapril in the treatment of hypertension in Ethiopia - Pilot study

2018

Conference Publication

A pilot aquatic exercise program to improve the health and wellbeing of people with dementia and their family carers

Neville, C., Zamora, A., Neville, E., Nikles, J., Lindgren, A. and Ansari, S. (2018). A pilot aquatic exercise program to improve the health and wellbeing of people with dementia and their family carers. UQ medical student research conference , Brisbane, QLD, Australia, 2018.

A pilot aquatic exercise program to improve the health and wellbeing of people with dementia and their family carers

2018

Conference Publication

Melatonin for insomnia in stimulant-treated ADHD – the value of N-of-1 trials

Nikles, J., Heussler, H. and McGree, J. (2018). Melatonin for insomnia in stimulant-treated ADHD – the value of N-of-1 trials. NHMRC Symposium on Research Translation, Sydney, NSW Australia, 2018.

Melatonin for insomnia in stimulant-treated ADHD – the value of N-of-1 trials

2018

Conference Publication

A retrospective descriptive study of patients who presented to an Australian hospital emergency department with neck soft tissue injury

Nikles, J., Khan, S., Leou, J., Keijzers, G., Ng, J., Bond, C., Nakamura, G., Le, R. and Sterling, M. (2018). A retrospective descriptive study of patients who presented to an Australian hospital emergency department with neck soft tissue injury. BrisPain Multidisciplinary conference, Brisbane, QLD, Australia, 6 December 2018.

A retrospective descriptive study of patients who presented to an Australian hospital emergency department with neck soft tissue injury

2018

Conference Publication

Managing symptoms of ME/CFS using scientific insights from N-of-1 studies

Tan, S., McDonald, S., McGree, J., Mitchell, G. and Nikles, J. (2018). Managing symptoms of ME/CFS using scientific insights from N-of-1 studies. CFS/ME International Conference , Gold Coast, QLD, Australia, 2018.

Managing symptoms of ME/CFS using scientific insights from N-of-1 studies

2018

Conference Publication

An aquatic exercise program to reduce behavioural and psychological symptoms in people with dementia: pilot study for a multi-centre, cluster-randomised, controlled trial

Neville, C., Beatty, E., Field, E., Pavey, T., Dawson, R., Nikles, J., Neville, E., Lindgren, A. and Banu, S. (2018). An aquatic exercise program to reduce behavioural and psychological symptoms in people with dementia: pilot study for a multi-centre, cluster-randomised, controlled trial. UQ Medical Student research conference , Brisbane, QLD, Australia, 2018.

An aquatic exercise program to reduce behavioural and psychological symptoms in people with dementia: pilot study for a multi-centre, cluster-randomised, controlled trial

2017

Journal Article

Management of whiplash associated disorders in Australian general practice

Nikles, Jane, Yelland, Michael, Bayram, Clare, Miller, Graeme and Sterling, Michele (2017). Management of whiplash associated disorders in Australian general practice. BMC Musculoskeletal Disorders, 18 (1) 551, 551. doi: 10.1186/s12891-017-1899-0

Management of whiplash associated disorders in Australian general practice

2017

Journal Article

Sun protective behaviors at an outdoor entertainment event in Australia

Barrett, Fiona, Usher, Kim, Woods, Cindy, Harrison, Simone L, Nikles, Jane and Conway, Jane (2017). Sun protective behaviors at an outdoor entertainment event in Australia. Nursing and Health Sciences, 20 (1), 132-138. doi: 10.1111/nhs.12396

Sun protective behaviors at an outdoor entertainment event in Australia

2017

Journal Article

A series of N-of-1 trials to assess therapeutic interchangeability of two Enalapril formulations in the treatment of hypertension, Addis Ababa, Ethiopia

Alemayu, Chalachew, Mitchell, Geoffrey, Aseffa, Abraham, Clavarino, Alexandra, McGree, James and Nikles, Jane (2017). A series of N-of-1 trials to assess therapeutic interchangeability of two Enalapril formulations in the treatment of hypertension, Addis Ababa, Ethiopia. Trials, 18 (1) 470, 470. doi: 10.1186/s13063-017-2212-0

A series of N-of-1 trials to assess therapeutic interchangeability of two Enalapril formulations in the treatment of hypertension, Addis Ababa, Ethiopia

2017

Journal Article

A series of n-of-1 trials of stimulants in brain injured children

Nikles, Jane, Mitchell, Geoffrey, McKinlay, Lynne, Waugh, Mary-Clare, Epps, Adrienne, Carmont, Sue-Ann, Schluter, Philip J., Lloyd, Owen and Senior, Hugh (2017). A series of n-of-1 trials of stimulants in brain injured children. NeuroRehabilitation, 40 (1), 11-21. doi: 10.3233/NRE-161386

A series of n-of-1 trials of stimulants in brain injured children

2017

Conference Publication

N-of-1 therapeutic equivalence trial of two formulations of Enalapril in the treatment of hypertension, Ethiopia

Alemayhu, Chalachew , Mitchell, Geoffrey , Nikles, Jane , Aseffa, Abraham , Clavarino, Alexandra and McGree, James (2017). N-of-1 therapeutic equivalence trial of two formulations of Enalapril in the treatment of hypertension, Ethiopia. PCRIS, Brisbane, Australia, 7-9 August 2017.

N-of-1 therapeutic equivalence trial of two formulations of Enalapril in the treatment of hypertension, Ethiopia

2017

Journal Article

The single-case reporting guideline in behavioural interventions (SCRIBE) 2016 statement

Tate, Robyn L., Perdices, Michael, Rosenkoetter, Ulrike, Shadish, William, Vohra, Sunita, Barlow, David H., Horner, Robert, Kazdin, Alan, Kratochwill, Thomas, McDonald, Skye, Sampson, Margaret, Shamseer, Larissa, Togher, Leanne, Albin, Richard, Backman, Catherine, Douglas, Jacinta, Evans, Jonathan J., Gast, David, Manolov, Rumen, Mitchell, Geoffrey, Nickels, Lyndsey, Nikles, Jane, Ownsworth, Tamara, Rose, Miranda, Schmid, Christopher H. and Wilson, Barbara (2017). The single-case reporting guideline in behavioural interventions (SCRIBE) 2016 statement. Neuropsychological Rehabilitation, 27 (1), 1-15. doi: 10.1080/09602011.2016.1190533

The single-case reporting guideline in behavioural interventions (SCRIBE) 2016 statement

2016

Journal Article

The single-case reporting guideline in BEhavioural Interventions (SCRIBE) 2016 statement

Tate, Robyn L., Perdices, Michael, Rosenkoetter, Ulrike, Shadish, William, Vohra, Sunita, Barlow, David H., Horner, Robert, Kazdin, Alan, Kratochwill, Thomas, McDonald, Skye, Sampson, Margaret, Shamseer, Larissa, Togher, Leanne, Albin, Richard, Backman, Catherine, Douglas, Jacinta, Evans, Jonathan J., Gast, David, Manolov, Rumen, Mitchell, Geoffrey, Nickels, Lyndsey, Nikles, Jane, Ownsworth, Tamara, Rose, Miranda, Schmid, Christopher H. and Wilson, Barbara (2016). The single-case reporting guideline in BEhavioural Interventions (SCRIBE) 2016 statement. Remedial and Special Education, 37 (6), 370-380. doi: 10.1177/0741932516652893

The single-case reporting guideline in BEhavioural Interventions (SCRIBE) 2016 statement

2016

Journal Article

Melatonin in youth: N-of-1 trials in a stimulant-treated ADHD Population (MYNAP): study protocol for a randomized controlled trial

Punja, Salima, Nikles, Catherine J., Senior, Hugh, Mitchell, Geoffrey, Schmid, Christopher H., Heussler, Helen, Witmans, Manisha and Vohra, Sunita (2016). Melatonin in youth: N-of-1 trials in a stimulant-treated ADHD Population (MYNAP): study protocol for a randomized controlled trial. Trials, 17 (1) 375, 375. doi: 10.1186/s13063-016-1499-6

Melatonin in youth: N-of-1 trials in a stimulant-treated ADHD Population (MYNAP): study protocol for a randomized controlled trial

2016

Journal Article

The Single-Case Reporting guideline In BEhavioural interventions (SCRIBE) 2016 statement

Tate, Robyn L., Perdices, Michael, Rosenkoetter, Ulrike, Shadish, William, Vohra, Sunita, Barlow, David H., Horner, Robert, Kazdin, Alan, Kratochwill, Thomas, McDonald, Skye, Sampson, Margaret, Shamseer, Larissa, Togher, Leanne, Albin, Richard, Backman, Catherine, Douglas, Jacinta, Evans, Jonathan J., Gast, David, Manolov, Rumen, Mitchell, Geoffrey, Nickels, Lyndsey, Nikles, Jane, Ownsworth, Tamara, Rose, Miranda, Schmid, Christopher H. and Wilson, Barbara (2016). The Single-Case Reporting guideline In BEhavioural interventions (SCRIBE) 2016 statement. Aphasiology, 30 (7), 862-876. doi: 10.1080/02687038.2016.1178022

The Single-Case Reporting guideline In BEhavioural interventions (SCRIBE) 2016 statement

2016

Journal Article

Do N-of-1 trials need IRB review?

Cen, Ruiqi, Hussain, Azad, Pak, Kirk J., Mitchell, Geoffrey, Nikles, Jane, Gaudreau, Stephanie, Bazzano, Lydia A. and Breault, Joseph L. (2016). Do N-of-1 trials need IRB review?. Journal of Empirical Research on Human Research Ethics, 11 (3), 250-255. doi: 10.1177/1556264616662560

Do N-of-1 trials need IRB review?

2016

Journal Article

The single-case reporting guideline in BEhavioural interventions (SCRIBE) 2016 Statement

Tate, Robyn L., Perdices, Michael, Rosenkoetter, Ulrike, Shadish, William, Vohra, Sunita, Barlow, David H., Horner, Robert, Kazdin, Alan, Kratochwill, Thomas, McDonald, Skye, Sampson, Margaret, Shamseer, Larissa, Togher, Leanne, Albin, Richard, Backman, Catherine, Douglas, Jacinta, Evans, Jonathan J., Gast, David, Manolov, Rumen, Mitchell, Geoffrey, Nickels, Lyndsey, Nikles, Jane, Ownsworth, Tamara, Rose, Miranda, Schmid, Christopher H. and Wilson, Barbara (2016). The single-case reporting guideline in BEhavioural interventions (SCRIBE) 2016 Statement. Physical Therapy, 96 (7), e1-e10. doi: 10.2522/ptj.2016.96.7.e1

The single-case reporting guideline in BEhavioural interventions (SCRIBE) 2016 Statement

2016

Journal Article

The Single-Case Reporting Guideline In BEhavioural Interventions (SCRIBE) 2016 Statement

Tate, Robyn L., Perdices, Michael, Rosenkoetter, Ulrike, Shadish, William, Vohra, Sunita, Barlow, David H., Horner, Robert, Kazdin, Alan, Kratochwill, Thomas, McDonald, Skye, Sampson, Margaret, Shamseer, Larissa, Togher, Leanne, Albin, Richard, Backman, Catherine, Douglas, Jacinta, Evans, Jonathan J., Gast, David, Manolov, Rumen, Mitchell, Geoffrey, Nickels, Lyndsey, Nikles, Jane, Ownsworth, Tamara, Rose, Miranda, Schmid, Christopher H. and Wilson, Barbara (2016). The Single-Case Reporting Guideline In BEhavioural Interventions (SCRIBE) 2016 Statement. Evidence-Based Communication Assessment and Intervention, 10 (1), 44-58. doi: 10.1080/17489539.2016.1190525

The Single-Case Reporting Guideline In BEhavioural Interventions (SCRIBE) 2016 Statement

2016

Journal Article

The Single-Case Reporting Guideline in BEhavioural Interventions (SCRIBE) 2016 statement

Tate, Robyn L., Perdices, Michael, Rosenkoetter, Ulrike, Shadish, William, Vohra, Sunita, Barlow, David H., Horner, Robert, Kazdin, Alan, Kratochwill, Thomas, McDonald, Skye, Sampson, Margaret, Shamseer, Larissa, Togher, Leanne, Albin, Richard, Backman, Catherine, Douglas, Jacinta, Evans, Jonathan J., Gast, David, Manolov, Rumen, Mitchell, Geoffrey, Nickels, Lyndsey, Nikles, Jane, Ownsworth, Tamara, Rose, Miranda, Schmid, Christopher H. and Wilson, Barbara (2016). The Single-Case Reporting Guideline in BEhavioural Interventions (SCRIBE) 2016 statement. Canadian Journal of Occupational Therapy, 83 (3), 184-195. doi: 10.1177/0008417416648124

The Single-Case Reporting Guideline in BEhavioural Interventions (SCRIBE) 2016 statement

Availability

Associate Professor Jane Nikles is:
Available for supervision

Looking for a supervisor? Read our advice on how to choose a supervisor.

Available projects

  • Opioid use and misuse following road traffic musculoskeletal injury

    Recent research by our group has shown that opioids are inappropriately prescribed for people with musculoskeletal pain after a road traffic crash. This project will explore this issue by longitudinal investigation of opioid use after injury and by using qualitative methods to explore reasons underlying opioid use in injured people and health care providers. It will also explore the physiotherapist's role in preventing opioid misuse.

  • N-of-1 trials in health care, melatonin, complementary and alternative medicines.

    N-of-1 trials in health care, melatonin, complementary and alternative medicines.

    Projects available mostly on clinical neuroscience topics – eg sleep, pain – but discussion on other topics welcome.

    Please contact me on uqjnikle@uq.edu.au to discuss several available projects.

Supervision history

Completed supervision

Enquiries

Contact Associate Professor Jane Nikles directly for media enquiries about:

  • ADHD
  • children
  • Clinical trials
  • General practice research
  • individualised treatments
  • melatonin
  • N-of-1 trials
  • Parkinson's Disease
  • Personalised medicine
  • Single Case Experimental Designs
  • sleep

Need help?

For help with finding experts, story ideas and media enquiries, contact our Media team:

communications@uq.edu.au