Skip to menu Skip to content Skip to footer
Dr

John Kemp

Email: 

Overview

Background

John Kemp is a senior research fellow at the University of Queensland. He first developed a keen interest in genetics while studying a Bachelor of Science at the University of Pretoria (RSA). After being awarded a first for his honours degree, he secured a scholarship from the University of Newcastle upon Tyne (UK) to study a master’s degree in medical genetics, which he subsequently completed with distinction. John was awarded a Wellcome Trust PhD studentship in molecular genetics and life-course epidemiology at the University of Bristol (UK). He duly completed his PhD, focussing on the genetics of osteoporosis (OP). His expertise lies in the genetic mapping of complex traits related to OP, and his research has yielded a step change in understanding the genetic architecture of OP. Through his extensive network of experts in functional genomics and murine genetics, he has mapped may OP loci to target genes and identified nine genes that represent new opportunities for drug development. These findings have since been published in top-tier journals such as Nature Genetics, and his contributions have been further recognised by the way of several international young investigator awards. His other interests include applying new statistical genetics methodologies to OP research, including approaches for causal modelling through Mendelian Randomization. John’s expertise extends beyond statistical genetics, as he has >6 years of experience performing advanced molecular genetics laboratory techniques and has used these to advance his OP research.

Availability

Dr John Kemp is:
Available for supervision

Qualifications

  • Masters (Coursework) of Science, Newcastle University
  • Doctor of Philosophy, University of Bristol

Research interests

  • Identifying pharmacological targets for osteoporosis intervention.

    Osteoporosis is a debilitating disease characterized by weak bones and increased risk of fracture. This research applies innovative statistical and molecular genetic methods to the world’s largest study of osteoporosis in order to identify genes, proteins and metabolites that may in the future serve as pharmacological targets to restore lost bone and prevent fracture.

Works

Search Professor John Kemp’s works on UQ eSpace

140 works between 2009 and 2026

101 - 120 of 140 works

2013

Journal Article

Nine loci for ocular axial length identified through genome-wide association studies, including shared loci with refractive error

Cheng C.-Y., Schache M., Ikram M.K., Young T.L., Guggenheim J.A., Vitart V., MacGregor S., Verhoeven V.J.M., Barathi V.A., Liao J., Hysi P.G., Bailey-Wilson J.E., St. Pourcain B., Kemp J.P., McMahon G., Timpson N.J., Evans D.M., Montgomery G.W., Mishra A., Wang Y.X., Wang J.J., Rochtchina E., Polasek O., Wright A.F., Amin N., Van Leeuwen E.M., Wilson J.F., Pennell C.E., Van Duijn C.M. ... Consortium for Refractive Error and Myopia (2013). Nine loci for ocular axial length identified through genome-wide association studies, including shared loci with refractive error. American Journal of Human Genetics, 93 (2), 264-277. doi: 10.1016/j.ajhg.2013.06.016

Nine loci for ocular axial length identified through genome-wide association studies, including shared loci with refractive error

2013

Journal Article

Meta-analysis of genome-wide association studies identifies ten loci influencing allergic sensitization

Bønnelykke, Klaus, Matheson, Melanie C., Pers, Tune H., Granell, Raquel, Strachan, David P., Alves, Alexessander Couto, Linneberg, Allan, Curtin, John A., Warrington, Nicole M., Standl, Marie, Kerkhof, Marjan, Jonsdottir, Ingileif, Bukvic, Blazenka K., Kaakinen, Marika, Sleimann, Patrick, Thorleifsson, Gudmar, Thorsteinsdottir, Unnur, Schramm, Katharina, Baltic, Svetlana, Kreiner-Møller, Eskil, Simpson, Angela, St Pourcain, Beate, Coin, Lachlan, Hui, Jennie, Walters, Eugene H., Tiesler, Carla M. T., Duffy, David L., Jones, Graham, Ring, Susan M. ... Brown, Matthew A. (2013). Meta-analysis of genome-wide association studies identifies ten loci influencing allergic sensitization. Nature Genetics, 45 (8), 902-906. doi: 10.1038/ng.2694

Meta-analysis of genome-wide association studies identifies ten loci influencing allergic sensitization

2013

Journal Article

Genome-wide association and longitudinal analyses reveal genetic loci linking pubertal height growth, pubertal timing and childhood adiposity

Cousminer D.L., Berry D.J., Timpson N.J., Ang W., Thiering E., Byrne E.M., Rob Taal H., Huikari V., Bradfield J.P., Kerkhof M., Groen-Blokhuis M.M., Kreiner-Moller E., Marinelli M., Holst C., Leinonen J.T., Perry J.R.B., Surakka I., Pietilainen O., Kettunen J., Anttila V., Kaakinen M., Sovio U., Pouta A., Das S., Lagou V., Power C., Prokopenko I., Evans D.M., Kemp J.P. ... Middeldorp, Christel (2013). Genome-wide association and longitudinal analyses reveal genetic loci linking pubertal height growth, pubertal timing and childhood adiposity. Human Molecular Genetics, 22 (13), 2735-2747. doi: 10.1093/hmg/ddt104

Genome-wide association and longitudinal analyses reveal genetic loci linking pubertal height growth, pubertal timing and childhood adiposity

2013

Journal Article

Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders

den Hoed, Marcel, Eijgelsheim, Mark, Esko, Tonu, Brundel, Bianca J. J. M., Peal, David S., Evans, David M., Nolte, Ilja M., Segre, Ayellet V., Holm, Hilma, Handsaker, Robert E., Westra, Harm-Jan, Johnson, Toby, Isaacs, Aaron, Yang, Jian, Lundby, Alicia, Zhao, Jing Hua, Kim, Young Jin, Go, Min Jin, Almgren, Peter, Bochud, Murielle, Boucher, Gabrielle, Cornelis, Marilyn C., Gudbjartsson, Daniel, Hadley, David, van der Harst, Pim, Hayward, Caroline, den Heijer, Martin, Igl, Wilmar, Jackson, Anne U. ... Loos, Ruth J. F. (2013). Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders. Nature Genetics, 45 (6), 621-634. doi: 10.1038/ng.2610

Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders

2013

Journal Article

Genome-wide association study identifies loci affecting blood copper, selenium and zinc.

Evans, David M., Zhu, Gu, Dy, Veronica, Heath, Andrew C., Madden, Pamela A. F., Kemp, John P., McMahon, George, St Pourcain, Beate, Timpson, Nicholas J., Golding, Jean, Lawlor, Debbie A., Steer, Colin, Montgomery, Grant W., Martin, Nicholas G, Smith, George Davey and Whitfield, John B. (2013). Genome-wide association study identifies loci affecting blood copper, selenium and zinc.. Human Molecular Genetics, 22 (19), 3998-4006. doi: 10.1093/hmg/ddt239

Genome-wide association study identifies loci affecting blood copper, selenium and zinc.

2013

Journal Article

Genome-wide meta-analyses of multiancestry cohorts identify multiple new susceptibility loci for refractive error and myopia (vol 45, pg 314, 2013)

Verhoeven, Virginie J. M., Hysi, Pirro G., Wojciechowski, Robert, Fan, Qiao, Guggenheim, Jeremy A., Hoehn, Rene, MacGregor, Stuart, Hewitt, Alex W., Nag, Abhishek, Cheng, Ching-Yu, Yonova-Doing, Ekaterina, Zhou, Xin, Ikram, M. Kamran, Buitendijk, Gabrielle H. S., McMahon, George, Kemp, John P., St Pourcain, Beate, Simpson, Claire L., Makela, Kari-Matti, Lehtimaki, Terho, Kahonen, Mika, Paterson, Andrew D., Hosseini, S. Mohsen, Wong, Hoi Suen, Xu, Liang, Jonas, Jost B., Parssinen, Olavi, Wedenoja, Juho, Yip, Shea Ping ... Hammond, Christopher J. (2013). Genome-wide meta-analyses of multiancestry cohorts identify multiple new susceptibility loci for refractive error and myopia (vol 45, pg 314, 2013). Nature Genetics, 45 (6), 712-712. doi: 10.1038/ng0613-712b

Genome-wide meta-analyses of multiancestry cohorts identify multiple new susceptibility loci for refractive error and myopia (vol 45, pg 314, 2013)

2013

Journal Article

Corrigendum: Common variants at 12q15 and 12q24 are associated with infant head circumference (vol 44, pg 532, 2012)

Taal, H. Rob, St Pourcain, Beate, Thiering, Elisabeth, Das, Shikta, Mook-Kanamori, Dennis O., Warrington, Nicole M., Kaakinen, Marika, Kreiner-Moller, Eskil, Bradfield, Jonathan P., Freathy, Rachel M., Geller, Frank, Guxens, Monica, Cousminer, Diana L., Kerkhof, Marjan, Timpson, Nicholas J., Ikram, M. Arfan, Beilin, Lawrence J., Bonnelykke, Klaus, Buxton, Jessica L., Charoen, Pimphen, Chawes, Bo Lund Krogsgaard, Eriksson, Johan, Evans, David M., Hofman, Albert, Kemp, John P., EKim, Cecilia, Klopp, Norman, Lahti, Jari, Lye, Stephen J. ... Jaddoe, Vincent W. V. (2013). Corrigendum: Common variants at 12q15 and 12q24 are associated with infant head circumference (vol 44, pg 532, 2012). Nature Genetics, 45 (6), 713-713. doi: 10.1038/ng0613-713a

Corrigendum: Common variants at 12q15 and 12q24 are associated with infant head circumference (vol 44, pg 532, 2012)

2013

Journal Article

Using genetic proxies for lifecourse sun exposure to assess the causal relationship of sun exposure with circulating vitamin d and prostate cancer risk

Bonilla, C., Gilbert, R., Kemp, J. P., Timpson, N. J., Evans, D. M., Donovan, J. L., Hamdy, F. C., Neal, D. E., Fraser, W. D., Smith, G. D., Lewis, S. J., Lathrop, M. and Martin, R. M. (2013). Using genetic proxies for lifecourse sun exposure to assess the causal relationship of sun exposure with circulating vitamin d and prostate cancer risk. Cancer Epidemiology Biomarkers and Prevention, 22 (4), 597-606. doi: 10.1158/1055-9965.EPI-12-1248

Using genetic proxies for lifecourse sun exposure to assess the causal relationship of sun exposure with circulating vitamin d and prostate cancer risk

2013

Journal Article

Genome-wide meta-analyses of multiancestry cohorts identify multiple new susceptibility loci for refractive error and myopia

Verhoeven V.J.M., Hysi P.G., Wojciechowski R., Fan Q., Guggenheim J.A., Hohn R., Macgregor S., Hewitt A.W., Nag A., Cheng C.-Y., Yonova-Doing E., Zhou X., Ikram M.K., Buitendijk G.H.S., Mcmahon G., Kemp J.P., Pourcain B.S., Simpson C.L., Makela K.-M., Lehtimaki T., Kahonen M., Paterson A.D., Hosseini S.M., Wong H.S., Xu L., Jonas J.B., Parssinen O., Wedenoja J., Yip S.P. ... Hammond C.J. (2013). Genome-wide meta-analyses of multiancestry cohorts identify multiple new susceptibility loci for refractive error and myopia. Nature Genetics, 45 (3), 314-318. doi: 10.1038/ng.2554

Genome-wide meta-analyses of multiancestry cohorts identify multiple new susceptibility loci for refractive error and myopia

2013

Journal Article

Examination of the relationship between variation at 17q21 and childhood wheeze phenotypes

Granell, R., Henderson A. J., Timpson, N., St. Pourcain, B., Kemp, J. P., Ring, S. M., Ho, K., Montgomery, S. B., Dermitzakis, E. T., Evans, D. M. and Sterne, J. A. C. (2013). Examination of the relationship between variation at 17q21 and childhood wheeze phenotypes. Journal of Allergy and Clinical Immunology, 131 (3), 685-694. doi: 10.1016/j.jaci.2012.09.021

Examination of the relationship between variation at 17q21 and childhood wheeze phenotypes

2013

Journal Article

Meta-analysis of genome-wide studies identifies WNT16 and ESR1 SNPs associated with bone mineral density in premenopausal women

Koller D.L., Zheng H.-F., Karasik D., Yerges-Armstrong L., Liu C.-T., McGuigan F., Kemp J.P., Giroux S., Lai D., Edenberg H.J., Peacock M., Czerwinski S.A., Choh A.C., McMahon G., St Pourcain B., Timpson N.J., Lawlor D.A., Evans D.M., Towne B., Blangero J., Carless M.A., Kammerer C., Goltzman D., Kovacs C.S., Prior J.C., Spector T.D., Rousseau F., Tobias J.H., Akesson K. ... Foroud T. (2013). Meta-analysis of genome-wide studies identifies WNT16 and ESR1 SNPs associated with bone mineral density in premenopausal women. Journal of Bone and Mineral Research, 28 (3), 547-558. doi: 10.1002/jbmr.1796

Meta-analysis of genome-wide studies identifies WNT16 and ESR1 SNPs associated with bone mineral density in premenopausal women

2013

Journal Article

Coordinated genetic scaling of the human eye: Shared determination of axial eye length and corneal curvature

Guggenheim, J. A., Zhou, X., Evans, D. M., Timpson, N. J., McMahon, G., Kemp, J. P., Pourcain, B. S., Northstone, K., Ring, S. M., Fan, Q., Wong, T. -Y., Cheng, C. Y., Khor, C. C., Aung, T., Saw, S. M. and Williams, C. (2013). Coordinated genetic scaling of the human eye: Shared determination of axial eye length and corneal curvature. Investigative Ophthalmology and Visual Science, 54 (3), 1715-1721. doi: 10.1167/iovs.12-10560

Coordinated genetic scaling of the human eye: Shared determination of axial eye length and corneal curvature

2013

Journal Article

Genetic determinants of trabecular and cortical volumetric bone mineral densities and bone microstructure

Paternoster, Lavinia, Lorentzon, Mattias, Lehtimaki, Terho, Eriksson, Joel, Kahonen, Mika, Raitakari, Olli, Laaksonen, Marika, Sievanen, Harri, Viikari, Jorma V, Lyytikainen, Leo-Pekka, Mellstrom, Dan, Karlsson, Magnus, Ljunggren, Osten, Grundberg, Elin, Kemp, John P., Sayers, Adrian, Nethander, Maria, Evans, David M., Vandenput, Liesbeth, Tobias, Jon H. and Ohlsson, Claes (2013). Genetic determinants of trabecular and cortical volumetric bone mineral densities and bone microstructure. PLoS Genetics, 9 (2) e1003247, 1-15. doi: 10.1371/journal.pgen.1003247

Genetic determinants of trabecular and cortical volumetric bone mineral densities and bone microstructure

2013

Journal Article

A genome-wide association study for corneal curvature identifies the platelet-derived growth factor receptor alpha gene as a quantitative trait locus for eye size in white Europeans

Guggenheim, Jeremy A., McMahon, George, Kemp, John P., Akhtar, Saeed, St Pourcain, Beate, Northstone, Kate, Ring, Susan M., Evans, David M., Smith, George Davey, Timpson, Nicholas J. and Williams, Cathy (2013). A genome-wide association study for corneal curvature identifies the platelet-derived growth factor receptor alpha gene as a quantitative trait locus for eye size in white Europeans. Molecular Vision, 19, 243-253.

A genome-wide association study for corneal curvature identifies the platelet-derived growth factor receptor alpha gene as a quantitative trait locus for eye size in white Europeans

2013

Journal Article

Body stature growth trajectories during childhood and the development of myopia

Northstone, Kate, Guggenheim, Jeremy A., Howe, Laura D., Tilling, Kate, Paternoster, Lavinia, Kemp, John P., McMahon, George and Williams, Cathy (2013). Body stature growth trajectories during childhood and the development of myopia. Ophthalmology, 120 (5), 1064-1073. doi: 10.1016/j.ophtha.2012.11.004

Body stature growth trajectories during childhood and the development of myopia

2013

Journal Article

Genome-wide association study of primary tooth eruption identifies pleiotropic loci associated with height and craniofacial distances

Fatemifar, Ghazaleh, Hoggart, Clive J., Paternoster, Lavinia, Kemp, John P., Prokopenko, Inga, Horikoshi, Momoko, Wright, Victoria J., Tobias, Jon H., Richmond, Stephen, Zhurov, Alexei I., Toma, Arshed M., Pouta, Anneli, Taanila, Anja, Sipila, Kirsi, Lahdesmaki, Raija, Pillas, Demetris, Geller, Frank, Feenstra, Bjarke, Melbye, Mads, Nohr, Ellen A., Ring, Susan M., St Pourcain, Beate, Timpson, Nicholas J., Smith, George D., Jarvelin, Marjo-Riitta and Evans, David M. (2013). Genome-wide association study of primary tooth eruption identifies pleiotropic loci associated with height and craniofacial distances. Human Molecular Genetics, 22 (18) ddt231, 3807-3817. doi: 10.1093/hmg/ddt231

Genome-wide association study of primary tooth eruption identifies pleiotropic loci associated with height and craniofacial distances

2013

Journal Article

New loci associated with birth weight identify genetic links between intrauterine growth and adult height and metabolism

Horikoshi M., Yaghootkar H., Mook-Kanamori D.O., Sovio U., Taal H.R., Hennig B.J., Bradfield J.P., St Pourcain B., Evans D.M., Charoen P., Kaakinen M., Cousminer D.L., Lehtimaki T., Kreiner-Moller E., Warrington N.M., Bustamante M., Feenstra B., Berry D.J., Thiering E., Pfab T., Barton S.J., Shields B.M., Kerkhof M., Van Leeuwen E.M., Fulford A.J., Kutalik Z., Zhao J.H., Den Hoed M., Mahajan A. ... Freathy R.M. (2013). New loci associated with birth weight identify genetic links between intrauterine growth and adult height and metabolism. Nature Genetics, 45 (1), 76-82. doi: 10.1038/ng.2477

New loci associated with birth weight identify genetic links between intrauterine growth and adult height and metabolism

2013

Journal Article

Common Variants in Left/Right Asymmetry Genes and Pathways Are Associated with Relative Hand Skill

Brandler, William M., Morris, Andrew P., Evans, David M., Scerri, Thomas S., Kemp, John P., Timpson, Nicholas J., St Pourcain, Beate, Smith, George Davey, Ring, Susan M., Stein, John, Monaco, Anthony P., Talcott, Joel B., Fisher, Simon E., Webber, Caleb and Paracchini, Silvia (2013). Common Variants in Left/Right Asymmetry Genes and Pathways Are Associated with Relative Hand Skill. PLoS Genetics, 9 (9) e1003751, e100375.1-e100375.11. doi: 10.1371/journal.pgen.1003751

Common Variants in Left/Right Asymmetry Genes and Pathways Are Associated with Relative Hand Skill

2013

Journal Article

Common variation contributes to the genetic architecture of social communication traits

St Pourcain, Beate, Whitehouse, Andrew J. O., Ang, Wei Q., Warrington, Nicole M., Glessner, Joseph T., Wang, Kai, Timpson, Nicholas J., Evans, David M., Kemp, John P., Ring,Susan M., McArdle, Wendy L., Golding, Jean, Hakonarson, Hakon, Pennell, Craig E. and Smith, George Davey (2013). Common variation contributes to the genetic architecture of social communication traits. Molecular Autism, 4 (1) 34, 34.1-34.12. doi: 10.1186/2040-2392-4-34

Common variation contributes to the genetic architecture of social communication traits

2013

Journal Article

Distinct relationships of intramuscular and subcutaneous fat with cortical bone: Findings from a cross-sectional study of young adult males and females

Deere, K., Sayers, A., Viljakainen, H. T., Lawlor, D. A., Sattar, N., Kemp, J. P., Fraser, W. D. and Tobias, J. H. (2013). Distinct relationships of intramuscular and subcutaneous fat with cortical bone: Findings from a cross-sectional study of young adult males and females. Journal of Clinical Endocrinology and Metabolism, 98 (6), E1041-E1049. doi: 10.1210/jc.2013-1272

Distinct relationships of intramuscular and subcutaneous fat with cortical bone: Findings from a cross-sectional study of young adult males and females

Funding

Current funding

  • 2025 - 2029
    Using human genetics, single cell transcriptomics and animal models to accelerate drug development for patients with osteoporosis.
    NHMRC Investigator Grants
    Open grant
  • 2023 - 2027
    Identifying genetic and lifestyle determinants of abdominal aortic calcification that predispose to cardiovascular disease (MRFF Cardiovascular Health Mission Grant administered by Edith Cowan Uni)
    Edith Cowan University
    Open grant

Past funding

  • 2021 - 2025
    Identifying drug targets for osteoporosis by synthesising murine single cell transcriptomics with data from human genetic association studies [ASBMR Rising Star Award]
    ASBMR Rising Star Award
    Open grant
  • 2020 - 2024
    Identifying pharmacological targets for osteoporosis intervention using whole genome and exome sequencing of bone related phenotypes
    NHMRC Investigator Grants
    Open grant
  • 2019 - 2023
    Using large scale genome-wide association studies to identify pharmacological targets for osteoporosis intervention
    NHMRC Project Grant
    Open grant
  • 2017 - 2020
    Identifying molecular genetic pathways and modifiable risk factors that underpin osteoporosis pathogenesis through genome-wide association and Mendelian randomization
    UQ Development Fellowships
    Open grant

Supervision

Availability

Dr John Kemp is:
Available for supervision

Looking for a supervisor? Read our advice on how to choose a supervisor.

Available projects

  • Identifying cellular and genetic determinants of osteoporosis and related co-morbidities

    Osteoporosis is a debilitating disease characterized by brittle bones and increased risk of fracture. This project applies innovative statistical and molecular genetic methods to the world’s largest study of osteoporosis in order to identify genes, proteins and metabolites that may in the future serve as pharmacological targets to restore lost bone and prevent fracture.

Supervision history

Current supervision

  • Doctor Philosophy

    Using single cell transcriptomics, gene-mapping, and animal models to accelerate drug discovery for patients with osteoporosis

    Principal Advisor

    Other advisors: Dr Nicole Warrington

Completed supervision

Media

Enquiries

For media enquiries about Dr John Kemp's areas of expertise, story ideas and help finding experts, contact our Media team:

communications@uq.edu.au