Professor James Fraser
Professor

James Fraser

Email: 
Phone: 
+61 7 336 54868

Availability

Professor James Fraser is:
Available for supervision

Fields of research

Genetics Medical microbiology Microbiology

Qualifications

  • Bachelor (Honours) of Science (Advanced), University of Melbourne
  • Doctor of Philosophy, unknown

Search Professor James Fraser’s works on UQ eSpace

102 works between 1984 and 2024
All (102) Journal Article (94) Book Chapter (2) Conference Publication (6)

81 - 100 of 102 works

2006

Journal Article

Yeast diversity sampling on the San Juan Islands reveals no evidence for the spread of the Vancouver Island Cryptococcus gattii outbreak to this locale

Fraser, J. A., Lim, S. M. C., Diezmann, S., Wenink, E. C., Arndt, C. G., Cox, G. M., Dietrich, F. S. and Heitman, J. (2006). Yeast diversity sampling on the San Juan Islands reveals no evidence for the spread of the Vancouver Island Cryptococcus gattii outbreak to this locale. Fems Yeast Research, 6 (4), 620-624. doi: 10.1111/j.1567-1364.2006.00075.x

Yeast diversity sampling on the San Juan Islands reveals no evidence for the spread of the Vancouver Island Cryptococcus gattii outbreak to this locale

2006

Conference Publication

The Cryptococcus neoformans mating-type locus: evolutionary insights from related species

Fraser, J (2006). The Cryptococcus neoformans mating-type locus: evolutionary insights from related species. 8th International Mycological Conference, Cairns, August, 2006.

The Cryptococcus neoformans mating-type locus: evolutionary insights from related species

2006

Journal Article

Recent evolution of the human pathogen Cryptococcus neoformans by intervarietal transfer of a 14-gene fragment

Kavanaugh, L. A., Fraser, J. A. and Dietrich, F. S. (2006). Recent evolution of the human pathogen Cryptococcus neoformans by intervarietal transfer of a 14-gene fragment. Molecular Biology And Evolution, 23 (10), 1879-1890. doi: 10.1093/molbev/msl070

Recent evolution of the human pathogen Cryptococcus neoformans by intervarietal transfer of a 14-gene fragment

2006

Book Chapter

Sex, MAT, and the Evolution of Fungal Virulence

Fraser, James A. and Heitman, Joseph (2006). Sex, MAT, and the Evolution of Fungal Virulence. Sex, MAT, and the Evolution of Fungal Virulence. (pp. 13-33) edited by Heitman, J, Filler, SG, Edwards, JE and Mitchell, AP. WASHINGTON: AMER SOC MICROBIOLOGY.

Sex, MAT, and the Evolution of Fungal Virulence

2005

Journal Article

The genome of the basidiomycetous yeast and human pathogen Cryptococcus neoformans

Loftus, B. J., Fung, E., Roncaglia, P., Rowley, D., Amedeo, P., Bruno, D., Vamathevan, J., Miranda, M., Anderson, I. J., Fraser, J. A., Allen, J. E., Bosdet, I. E., Brent, M. R., Chiu, R., Doering, T. L., Dontin, M. J., D'Souza, C. A., Fox, D. S., Grinberg, V., Fu, J. M., Fukushima, M., Haas, B. J., Huang, J. C., Janbon, G., Jones, S. J. M., Koo, H. L., Krzywinski, M. I., Kwon-Chung, J. K., Lengeler, K. B. and Maiti, R. (2005). The genome of the basidiomycetous yeast and human pathogen Cryptococcus neoformans. Science, 307 (5713), 1321-1324. doi: 10.1126/science.1103773

The genome of the basidiomycetous yeast and human pathogen Cryptococcus neoformans

2005

Journal Article

Nuclear accumulation of the GATA factor AreA in response to complete nitrogen starvation by regulation of nuclear export

Todd, R. B., Fraser, J. A., Wong, K. H., Davis, M. A. and Hynes, M. J. (2005). Nuclear accumulation of the GATA factor AreA in response to complete nitrogen starvation by regulation of nuclear export. Eukaryotic Cell, 4 (10), 1646-1653. doi: 10.1128/EC.4.10.1646-1653.2005

Nuclear accumulation of the GATA factor AreA in response to complete nitrogen starvation by regulation of nuclear export

2005

Journal Article

Chromosomal translocation and segmental duplication in Cryptococcus neoformans

Fraser, J. A., Huang, J. C., Pukkila-Worley, R., Alspaugh, J. A., Mitchell, T. G. and Heitman, J. (2005). Chromosomal translocation and segmental duplication in Cryptococcus neoformans. Eukaryotic Cell, 4 (2), 401-406. doi: 10.1128/EC.4.2.401-406.2005

Chromosomal translocation and segmental duplication in Cryptococcus neoformans

2005

Journal Article

Same-sex mating and the origin of the Vancouver Island Cryptococcus gattii outbreak

Fraser, J. A., Giles, S. S., Wenink, E. C., Geunes-Boyer, S. G., Wright, J. R., Diezmann, S., Allen, A., Stajich, J. E., Dietrich, F. S., Perfect, J. R. and Heitman, J. (2005). Same-sex mating and the origin of the Vancouver Island Cryptococcus gattii outbreak. Nature, 437 (7063), 1360-1364. doi: 10.1038/nature04220

Same-sex mating and the origin of the Vancouver Island Cryptococcus gattii outbreak

2005

Journal Article

Deciphering the model pathogenic fungus Cryptococcus neoformans

Idnurm, A., Bahn, Y. S., Nielsen, K., Lin, X. R., Fraser, J. A. and Heitman, J. (2005). Deciphering the model pathogenic fungus Cryptococcus neoformans. Nature Reviews Microbiology, 3 (10), 753-764. doi: 10.1038/nrmicro1245

Deciphering the model pathogenic fungus Cryptococcus neoformans

2005

Journal Article

Chromosomal sex-determining regions in animals, plants and fungi

Fraser, J. A. and Heitman, J. (2005). Chromosomal sex-determining regions in animals, plants and fungi. Current Opinion In Genetics & Development, 15 (6), 645-651. doi: 10.1016/j.gde.2005.09.002

Chromosomal sex-determining regions in animals, plants and fungi

2005

Journal Article

Clinical and environmental isolates of Cryptococcus gattii from Australia that retain sexual fecundity

Campbell, L. T., Fraser, J. A., Nichols, C. B., Dietrich, F. S., Dietrich and Heitman, J. (2005). Clinical and environmental isolates of Cryptococcus gattii from Australia that retain sexual fecundity. Eukaryotic Cell, 4 (8), 1410-1419. doi: 10.1128/EC.4.8.1410-1419.2005

Clinical and environmental isolates of Cryptococcus gattii from Australia that retain sexual fecundity

2004

Journal Article

Convergent evolution of chromosomal sex-determining regions in the animal and fungal kingdoms

Fraser, James A., Diezmann, Stephanie, Subaran, Ryan L., Allen, Andria, Lengeler, Klaus B., Dietrich, Fred S. and Heitman, Joseph (2004). Convergent evolution of chromosomal sex-determining regions in the animal and fungal kingdoms. Plos Biology, 2 (12), 2243-2255. doi: 10.1371/journal.pbio.0020384

Convergent evolution of chromosomal sex-determining regions in the animal and fungal kingdoms

2004

Journal Article

Evolution of fungal sex chromosomes

Fraser, J. A. and Heitman, J. (2004). Evolution of fungal sex chromosomes. Molecular Microbiology, 51 (2), 299-306. doi: 10.1046/j.1365-2958.2003.03874.x

Evolution of fungal sex chromosomes

2004

Journal Article

PAK kinases Ste20 and Pak1 govern cell polarity at different stages of mating in Cryptococcus neoformans

Nichols, C. B., Fraser, J. A. and Heitman, J. (2004). PAK kinases Ste20 and Pak1 govern cell polarity at different stages of mating in Cryptococcus neoformans. Molecular Biology of The Cell, 15 (10), 4476-4489. doi: 10.1091/mbc.E04-05-0370

PAK kinases Ste20 and Pak1 govern cell polarity at different stages of mating in Cryptococcus neoformans

2003

Journal Article

Fungal mating-type loci

Fraser, J. A. and Heitman, J. (2003). Fungal mating-type loci. Current Biology, 13 (20), R792-R795. doi: 10.1016/j.cub.2003.09.046

Fungal mating-type loci

2003

Journal Article

Recapitulation of the sexual cycle of the primary fungal pathogen Cryptococcus neoformans var. gattii: Implications for an outbreak on Vancouver Island, Canada

Fraser, James A., Subaran, Ryan L., Nichols, Connie B. and Heitman, Joseph (2003). Recapitulation of the sexual cycle of the primary fungal pathogen Cryptococcus neoformans var. gattii: Implications for an outbreak on Vancouver Island, Canada. Eukaryotic Cell, 2 (5), 1036-1045. doi: 10.1128/EC.2.5.1036-1045.2003

Recapitulation of the sexual cycle of the primary fungal pathogen Cryptococcus neoformans var. gattii: Implications for an outbreak on Vancouver Island, Canada

2002

Journal Article

Mating-type locus of Cryptococcus neoformans: A step in the evolution of sex chromosomes

Lengeler, Klaus B., Fox, Deborah S., Fraser, James A., Allen, Andria, Forrester, Keri, Dietrich, Fred S. and Heitman, Joseph (2002). Mating-type locus of Cryptococcus neoformans: A step in the evolution of sex chromosomes. Eukaryotic Cell, 1 (5), 704-718. doi: 10.1128/EC.1.5.704-718.2002

Mating-type locus of Cryptococcus neoformans: A step in the evolution of sex chromosomes

2002

Journal Article

A gene from Aspergillus nidulans with similarity to URE2 of Saccharomyces cerevisiae encodes a glutathione S-transferase which contributes to heavy metal and xenobiotic resistance

Fraser, J. A., Davis, M. A. and Hynes, M. J. (2002). A gene from Aspergillus nidulans with similarity to URE2 of Saccharomyces cerevisiae encodes a glutathione S-transferase which contributes to heavy metal and xenobiotic resistance. Applied And Environmental Microbiology, 68 (6), 2802-2808. doi: 10.1128/AEM.68.6.2802-2808.2002

A gene from Aspergillus nidulans with similarity to URE2 of Saccharomyces cerevisiae encodes a glutathione S-transferase which contributes to heavy metal and xenobiotic resistance

2002

Journal Article

Isolation and characterization of two ammonium permease genes, meaA and mepA, from Aspergillus nidulans

Monahan, B. J., Fraser, J. A., Hynes, M. J. and Davis, M. A. (2002). Isolation and characterization of two ammonium permease genes, meaA and mepA, from Aspergillus nidulans. Eukaryotic Cell, 1 (1), 85-94. doi: 10.1128/EC.1.1.85-94.2002

Isolation and characterization of two ammonium permease genes, meaA and mepA, from Aspergillus nidulans

2002

Journal Article

The genes gmdA, encoding an amidase, and bzuA, encoding a cytochrome P450, are required for benzamide utilization in Aspergillus nidulans

Fraser, J. A., Davis, M. A. and Hynes, M. J. (2002). The genes gmdA, encoding an amidase, and bzuA, encoding a cytochrome P450, are required for benzamide utilization in Aspergillus nidulans. Fungal Genetics And Biology, 35 (2), 135-146. doi: 10.1006/fgbi.2001.1307

The genes gmdA, encoding an amidase, and bzuA, encoding a cytochrome P450, are required for benzamide utilization in Aspergillus nidulans

Past funding

  • 2020 - 2023
    Novel Broad Spectrum Antifungals Active Against Drug Resistant Candida Auris
    NHMRC IDEAS Grants
    Open grant
  • 2019
    A versatile accurate mass, high resolution QTOF mass spectrometer for chemistry and proteomic applications
    UQ Major Equipment and Infrastructure
    Open grant
  • 2018
    Epifluorescent and live-cell imaging microscopes for the investigation of host-pathogen interactions and for molecular and cellular biology
    UQ Major Equipment and Infrastructure
    Open grant
  • 2017 - 2021
    Microevolution of Cryptococcus neoformans
    NHMRC Project Grant
    Open grant
  • 2015
    A sensitive, high resolution QTOF mass spectrometer with nanoUPLC system for qualitative and quantitative biomolecule analysis.
    UQ Major Equipment and Infrastructure
    Open grant
  • 2015 - 2018
    Acetohydroxyacid synthase: A new drug target for human fungal pathogens
    NHMRC Project Grant
    Open grant
  • 2014
    A confocal microscope for investigation of live bacterial and viral pathogens and for molecular cell biology
    UQ Major Equipment and Infrastructure
    Open grant
  • 2013 - 2016
    Purine metabolism as an antifungal drug target
    NHMRC Project Grant
    Open grant
  • 2012 - 2013
    IMPDH as an antifungal drug target
    Therapeutic Innovation Australia Limited
    Open grant
  • 2011 - 2014
    Targeting acetohydroxyacid synthase to discover new antifungal agents
    NHMRC Project Grant
    Open grant
  • 2010 - 2012
    ResTeach 2010 0.1 FTE School of Chemistry and Molecular Biosciences
    UQ ResTeach
    Open grant
  • 2010 - 2012
    Understanding an exotic disease: Initiation of sex and infection by the sugarcane smut Ustilago scitaminea
    ARC Discovery Projects
    Open grant
  • 2007 - 2010
    Transposable element mobility and chromosomal rearrangement in the fungal pathogen Cryptococcus during human infection
    NHMRC Project Grant
    Open grant

Availability

Professor James Fraser is:
Available for supervision

Before you email them, read our advice on how to contact a supervisor.

Supervision history

Current supervision

  • Doctor Philosophy

    The Cryptococcus neoformans SAGA: Investigating the SAGA associated Histone acetyltransferase and Deubiquitinase modules opposing influence on virulence

    Principal Advisor

    Other advisors: Professor Benjamin Schulz

  • Doctor Philosophy

    Antifungal agents to target disseminated mycoses

    Principal Advisor

    Other advisors: Dr Kylie Agnew-Francis, Professor Avril Robertson

  • Doctor Philosophy

    Purine biosynthesis as an anti fungal target

    Principal Advisor

    Other advisors: Professor Bostjan Kobe

  • Doctor Philosophy

    The role of the cotranscriptional activator complex SAGA in virulence of Cryptococcus neoformans

    Principal Advisor

    Other advisors: Professor Benjamin Schulz

  • Doctor Philosophy

    Advanced Genetic Toolkit for Cryptococcus neoformans: Iterating Upon Currently Used Techniques in the WHO¿s Top-Ranked Fungal Pathogen

    Principal Advisor

    Other advisors: Associate Professor Nick West

  • Doctor Philosophy

    Resolving a Dichotomy: A Journey between the Laboratory and the Classroom

    Principal Advisor

    Other advisors: Professor Bostjan Kobe

  • Doctor Philosophy

    Targetting Candida Auris

    Associate Advisor

    Other advisors: Dr Kylie Agnew-Francis, Professor Avril Robertson

  • Doctor Philosophy

    Developing a cell-free, structural model of fungal cell walls

    Associate Advisor

    Other advisors: Dr Evelyne Deplazes

  • Doctor Philosophy

    Targeting Deadly Mycotic Infection

    Associate Advisor

    Other advisors: Dr Kylie Agnew-Francis, Professor Avril Robertson

  • Doctor Philosophy

    Characterising the membrane interactions and cytotoxic activity of the anti-fungal peptide Lactofungin

    Associate Advisor

    Other advisors: Dr Evelyne Deplazes

Completed supervision

Enquiries

For media enquiries about Professor James Fraser's areas of expertise, story ideas and help finding experts, contact our Media team:

communications@uq.edu.au