Overview
Background
Professor Sarah Medland (OAM, FASSA, FAHMS, PhD) is a Psychiatric and Statistical Geneticist working in Neuroimaging and Mental health genetics. Her work bridges Genetics, Psychology, Neuro-Imaging, Health Economics and applied Statistics with a focus on understanding the genetic and environmental contributions to human behaviour and disease. She chairs the genetics working group of the ENIGMA neuroimaging consortium and is an active member of the Psychiatric Genomics Consortium.
Primary Appointment: Coordinator of the Mental Health Research Program and Group Leader (Psychiatric Genetics) QIMR Berghofer Medical Research Institute.
ORCID: 0000-0003-1382-380X
ResearcherID: C-7630-2013
Scopus Author ID: 34571085600
Email: sarah.medland@qimrberghofer.edu.au
Qualifications
2006 PhD (Psychology), University of Queensland
Dean's Award for Outstanding Research Higher Degree Thesis
2000 BA Hons (Psychology), University of Queensland, 2000 (Psychology Double Major, English Minor)
Availability
- Honorary Professor Sarah Medland is:
- Available for supervision
Fields of research
Works
Search Professor Sarah Medland’s works on UQ eSpace
2018
Journal Article
Significant concordance of genetic variation that increases both the risk for obsessive-compulsive disorder and the volumes of the nucleus accumbens and putamen
Hibar, Derrek P., Cheung, Joshua W., Medland, Sarah E., Mufford, Mary S., Jahanshad, Neda, Dalvie, Shareefa, Ramesar, Raj, Stewart, Evelyn, Van Den Heuvel, Odile A., Pauls, David L., Knowles, James A., Stein, Dan J. and Thompson, Paul M. (2018). Significant concordance of genetic variation that increases both the risk for obsessive-compulsive disorder and the volumes of the nucleus accumbens and putamen. British Journal of Psychiatry, 213 (1), 430-436. doi: 10.1192/bjp.2018.62
2018
Journal Article
Genome-wide association analysis links multiple psychiatric liability genes to oscillatory brain activity
Smit, Dirk J. A., Wright, Margaret J., Meyers, Jacquelyn L., Martin, Nicholas G., Ho, Yvonne Y. W., Malone, Stephen M., Zhang, Jian, Burwell, Scott J., Chorlian, David B., de Geus, Eco J. C., Denys, Damiaan, Hansell, Narelle K., Hottenga, Jouke-Jan, McGue, Matt, van Beijsterveldt, Catharina E. M., Jahanshad, Neda, Thompson, Paul M., Whelan, Christopher D., Medland, Sarah E., Porjesz, Bernice, Lacono, William G. and Boomsma, Dorret I. (2018). Genome-wide association analysis links multiple psychiatric liability genes to oscillatory brain activity. Human Brain Mapping, 39 (11), 4183-4195. doi: 10.1002/hbm.24238
2018
Journal Article
Genome-wide association meta-analysis in 269,867 individuals identifies new genetic and functional links to intelligence
Savage, Jeanne E., Jansen, Philip R., Stringer, Sven, Watanabe, Kyoko, Bryois, Julien, de Leeuw, Christiaan A., Nagel, Mats, Awasthi, Swapnil, Barr, Peter B., Coleman, Jonathan R. I., Grasby, Katrina L., Hammerschlag, Anke R., Kaminski, Jakob A., Karlsson, Robert, Krapohl, Eva, Lam, Max, Nygaard, Marianne, Reynolds, Chandra A., Trampush, Joey W., Young, Hannah, Zabaneh, Delilah, Hägg, Sara, Hansell, Narelle K., Karlsson, Ida K., Linnarsson, Sten, Montgomery, Grant W., Muñoz-Manchado, Ana B., Quinlan, Erin B., Schumann, Gunter ... Posthuma, Danielle (2018). Genome-wide association meta-analysis in 269,867 individuals identifies new genetic and functional links to intelligence. Nature Genetics, 50 (7), 912-919. doi: 10.1038/s41588-018-0152-6
2018
Journal Article
Extended twin study of alcohol use in Virginia and Australia
Verhulst, Brad, Neale, Michael C., Eaves, Lindon J., Medland, Sarah E., Heath, Andrew C., Martin, Nicholas G. and Maes, Hermine H. (2018). Extended twin study of alcohol use in Virginia and Australia. Twin Research and Human Genetics, 21 (3), 163-178. doi: 10.1017/thg.2018.21
2018
Journal Article
Childhood aggression and the co-occurrence of behavioural and emotional problems: results across ages 3-16 years from multiple raters in six cohorts in the EU-ACTION project
Bartels, Meike, Hendriks, Anne, Mauri, Matteo, Krapohl, Eva, Whipp, Alyce, Bolhuis, Koen, Conde, Lucia Colodro, Luningham, Justin, Fung Ip, Hill, Hagenbeek, Fiona, Roetman, Peter, Gatej, Raluca, Lamers, Audri, Nivard, Michel, van Dongen, Jenny, Lu, Yi, Middeldorp, Christel, van Beijsterveldt, Toos, Vermeiren, Robert, Hankemeijer, Thomas, Kluft, Cees, Medland, Sarah, Lundström, Sebastian, Rose, Richard, Pulkkinen, Lea, Vuoksimaa, Eero, Korhonen, Tellervo, Martin, Nicholas G., Lubke, Gitta ... Boomsma, Dorret I. (2018). Childhood aggression and the co-occurrence of behavioural and emotional problems: results across ages 3-16 years from multiple raters in six cohorts in the EU-ACTION project. European Child & Adolescent Psychiatry, 27 (9), 1-17. doi: 10.1007/s00787-018-1169-1
2018
Journal Article
Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression
Wray, Naomi R., Ripke, Stephan, Mattheisen, Manuel, Trzaskowski, Maciej, Byrne, Enda M., Abdellaoui, Abdel, Adams, Mark J., Agerbo, Esben, Air, Tracy M., Andlauer, Till M. F., Bacanu, Silviu-Alin, Baekvad-Hansen, Marie, Beekman, Aartjan F. T., Bigdeli, Tim B., Binder, Elisabeth B., Blackwood, Douglas R. H., Bryois, Julien, Buttenschon, Henriette N., Bybjerg-Grauholm, Jonas, Cai, Na, Castelao, Enrique, Christensen, Jane Hvarregaard, Clarke, Toni-Kim, Coleman, Jonathan I. R., Colodro-Conde, Lucia, Couvy-Duchesne, Baptiste, Craddock, Nick, Crawford, Gregory E., Crowley, Cheynna A. ... Sullivan, Patrick F. (2018). Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression. Nature Genetics, 50 (5), 668-+. doi: 10.1038/s41588-018-0090-3
2018
Journal Article
Genome-wide association meta-analysis of individuals of European ancestry identifies new loci explaining a substantial fraction of hair color variation and heritability
Hysi, Pirro G., Valdes, Ana M., Liu, Fan, Furlotte, Nicholas A., Evans, David M., Bataille, Veronique, Visconti, Alessia, Hemani, Gibran, McMahon, George, Ring, Susan M., Smith, George Davey, Duffy, David L., Zhu, Gu, Gordon, Scott D., Medland, Sarah E., Lin, Bochao D., Willemsen, Gonneke, Jan Hottenga, Jouke, Vuckovic, Dragana, Girotto, Giorgia, Gandin, Ilaria, Sala, Cinzia, Concas, Maria Pina, Brumat, Marco, Gasparini, Paolo, Toniolo, Daniela, Cocca, Massimiliano, Robino, Antonietta, Yazar, Seyhan ... Spector, Timothy D. (2018). Genome-wide association meta-analysis of individuals of European ancestry identifies new loci explaining a substantial fraction of hair color variation and heritability. Nature Genetics, 50 (5), 652-656. doi: 10.1038/s41588-018-0100-5
2018
Journal Article
Genome-wide association study identifies nine novel loci for 2D:4D finger ratio, a putative retrospective biomarker of testosterone exposure in utero
Warrington, Nicole M., Shevroja, Enisa, Hemani, Gibran, Hysi, Pirro G., Jiang, Yunxuan, Auton, Adam, Boer, Cindy G., Mangino, Massimo, Wang, Carol A., Kemp, John P., McMahon, George, Medina-Gomez, Carolina, Hickey, Martha, Trajanoska, Katerina, Wolke, Dieter, Ikram, Arfan M., 23 and Me Research Team, Montgomery, Grant W., Felix, Janine F., Wright, Margaret J., Mackey, David A., Jaddoe, Vincent W., Martin, Nicholas G., Tung, Joyce Y., Davey Smith, George, Pennell, Craig E., Spector, Tim D., van Meurs, Joyce, Rivadeneira, Fernando ... Evans, David M. (2018). Genome-wide association study identifies nine novel loci for 2D:4D finger ratio, a putative retrospective biomarker of testosterone exposure in utero. Human Molecular Genetics, 27 (11), 2025-2038. doi: 10.1093/hmg/ddy121
2018
Journal Article
Anticytokine autoantibodies in a patient with a heterozygous <i>NFKB2</i> mutation
Ramakrishnan, Kesava A., Rae, William, Barcenas-Morales, Gabriela, Gao, Yifang, Pengelly, Reuben J., Patel, Sanjay V., Kumararatne, Dinakantha S., Ennis, Sarah, Doffinger, Rainer, Faust, Saul N. and Williams, Anthony P. (2018). Anticytokine autoantibodies in a patient with a heterozygous NFKB2 mutation. Journal of Allergy and Clinical Immunology, 141 (4), 1479-+. doi: 10.1016/j.jaci.2017.11.014
2018
Journal Article
Nineteen and Up study (19Up): Understanding pathways to mental health disorders in young Australian twins
Couvy-Duchesne, Baptiste, O'Callaghan, Victoria, Parker, Richard, Mills, Natalie, Kirk, Katherine M., Scott, Jan, Vinkhuyzen, Anna., Hermens, Daniel F., Lind, Penelope A., Davenport, Tracey A., Burns, Jane M., Connell, Melissa, Zietsch, Brendan P., Scott, James, Wright, Margaret J., Medland, Sarah E., McGrath, John, Martin, Nicholas G., Hickie, Ian B. and Gillespie, Nathan A. (2018). Nineteen and Up study (19Up): Understanding pathways to mental health disorders in young Australian twins. BMJ Open, 8 (3) e018959, 1-13. doi: 10.1136/bmjopen-2017-018959
2018
Journal Article
Publisher Correction: protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity
Turcot, Valérie, Lu, Yingchang, Highland, Heather M., Schurmann, Claudia, Justice, Anne E., Fine, Rebecca S., Bradfield, Jonathan P., Esko, Tõnu, Giri, Ayush, Graff, Mariaelisa, Guo, Xiuqing, Hendricks, Audrey E., Karaderi, Tugce, Lempradl, Adelheid, Locke, Adam E., Mahajan, Anubha, Marouli, Eirini, Sivapalaratnam, Suthesh, Young, Kristin L., Alfred, Tamuno, Feitosa, Mary F., Masca, Nicholas G. D., Manning, Alisa K., Medina-Gomez, Carolina, Mudgal, Poorva, Ng, Maggie C. Y., Reiner, Alex P., Vedantam, Sailaja, Willems, Sara M. ... Loos, Ruth J. F. (2018). Publisher Correction: protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity. Nature Genetics, 50 (5), 1-2. doi: 10.1038/s41588-018-0082-3
2018
Journal Article
The Nature of Nurture: Using a Virtual-Parent Design to Test Parenting Effects on Children's Educational Attainment in Genotyped Families
Bates, Timothy C., Maher, Brion S., Medland, Sarah E., McAloney, Kerrie, Wright, Margaret J., Hansell, Narelle K., Kendler, Kenneth S., Martin, Nicholas G. and Gillespie, Nathan A. (2018). The Nature of Nurture: Using a Virtual-Parent Design to Test Parenting Effects on Children's Educational Attainment in Genotyped Families. Twin Research and Human Genetics, 21 (2), 73-83. doi: 10.1017/thg.2018.11
2018
Other Outputs
Trans-ancestral GWAS of alcohol dependence reveals common genetic underpinnings with psychiatric disorders
Walters, Raymond K., Adams, Mark J., Adkins, Amy E., Aliev, Fazil, Bacanu, Silviu-Alin, Batzler, Anthony, Bertelsen, Sarah, Biernacka, Joanna, Bigdeli, Tim B., Chen, Li-Shiun, Clarke, Toni-Kim, Chou, Yi-Ling, Degenhardt, Franziska, Docherty, Anna R., Fontanillas, Pierre, Foo, Jerome, Fox, Louis, Frank, Josef, Giegling, Ina, Gordon, Scott, Hack, Laura M., Hartmann, Annette M., Hartz, Sarah M., Heilmann-Heimbach, Stefanie, Herms, Stefan, Hodgkinson, Colin, Hoffmann, Per, Hottenga, Jouke-Jan, Kennedy, Martin A. ... Agrawal, Arpana (2018). Trans-ancestral GWAS of alcohol dependence reveals common genetic underpinnings with psychiatric disorders. doi: 10.1101/257311
2018
Journal Article
Gene set enrichment analysis and expression pattern exploration implicate an involvement of neurodevelopmental processes in bipolar disorder
Mühleisen, Thomas W., Reinbold, Céline S., Forstner, Andreas J., Abramova, Lilia I., Alda, Martin, Babadjanova, Gulja, Bauer, Michael, Brennan, Paul, Chuchalin, Alexander, Cruceanu, Cristiana, Czerski, Piotr M., Degenhardt, Franziska, Fischer, Sascha B., Fullerton, Janice M., Gordon, Scott D., Grigoroiu-Serbanescu, Maria, Grof, Paul, Hauser, Joanna, Hautzinger, Martin, Herms, Stefan, Hoffmann, Per, Kammerer-Ciernioch, Jutta, Khusnutdinova, Elza, Kogevinas, Manolis, Krasnov, Valery, Lacour, André, Laprise, Catherine, Leber, Markus, Lissowska, Jolanta ... Cichon, Sven (2018). Gene set enrichment analysis and expression pattern exploration implicate an involvement of neurodevelopmental processes in bipolar disorder. Journal of Affective Disorders, 228, 20-25. doi: 10.1016/j.jad.2017.11.068
2018
Journal Article
Genome-wide association study of offspring birth weight in 86,577 women identifies five novel loci and highlights maternal genetic effects that are independent of fetal genetics
Beaumont, Robin N., Warrington, Nicole M., Cavadino, Alana, Tyrrell, Jessica, Nodzenski, Michael, Horikoshi, Momoko, Geller, Frank, Myhre, Ronny, Richmond, Rebecca C., Paternoster, Lavinia, Bradfield, Jonathan P., Kreiner-Møller, Eskil, Huikari, Ville, Metrustry, Sarah, Lunetta, Kathryn L., Painter, Jodie N., Hottenga, Jouke-Jan, Allard, Catherine, Barton, Sheila J., Espinosa, Ana, Marsh, Julie A., Potter, Catherine, Zhang, Ge, Ang, Wei, Berry, Diane J., Bouchard, Luigi, Das, Shikta, Early Growth Genetics (EGG) Consortium, Hakonarson, Hakon ... Freathy, Rachel M. (2018). Genome-wide association study of offspring birth weight in 86,577 women identifies five novel loci and highlights maternal genetic effects that are independent of fetal genetics. Human Molecular Genetics, 27 (4) ddx429, 742-756. doi: 10.1093/hmg/ddx429
2018
Journal Article
No evidence of association of oxytocin polymorphisms with breastfeeding in 2 independent samples
Colodro-Conde, L., Sánchez-Romera, J. F., Lind, P. A., Zhu, G., Martin, N. G., Medland, S. E. and Ordoñana, J. R. (2018). No evidence of association of oxytocin polymorphisms with breastfeeding in 2 independent samples. Genes, Brain and Behavior, 17 (7) e12464, e12464. doi: 10.1111/gbb.12464
2018
Journal Article
The protocadherin 17 gene affects cognition, personality, amygdala structure and function, synapse development and risk of major mood disorders
Chang, H., Hoshina, N., Zhang, C., Ma, Y., Cao, H., Wang, Y., Wu, D. D., Bergen, S. E., Landén, M., Hultman, C. M., Preisig, M., Kutalik, Z., Castelao, E., Grigoroiu-Serbanescu, M., Forstner, A. J., Strohmaier, J., Hecker, J., Schulze, T. G., Müller-Myhsok, B., Reif, A., Mitchell, P. B., Martin, N. G., Schofield, P. R., Cichon, S., Nöthen, M. M., Walter, H., Erk, S., Heinz, A., Amin, N. ... MooDS Bipolar Consortium (2018). The protocadherin 17 gene affects cognition, personality, amygdala structure and function, synapse development and risk of major mood disorders. Molecular Psychiatry, 23 (2), 400-412. doi: 10.1038/mp.2016.231
2018
Journal Article
Meta-analysis of genome-wide association studies identifies 8 novel loci involved in shape variation of human head hair
Liu, Fan, Chen, Yan, Zhu, Gu, Hysi, Pirro G., Wu, Sijie, Adhikari, Kaustubh, Breslin, Krystal, Pośpiech, Ewelina, Hamer, Merel A., Peng, Fuduan, Muralidharan, Charanya, Acuna-Alonzo, Victor, Canizales-Quinteros, Samuel, Bedoya, Gabriel, Gallo, Carla, Poletti, Giovanni, Rothhammer, Francisco, Bortolini, Maria Catira, Gonzalez-Jose, Rolando, Zeng, Changqing, Xu, Shuhua, Jin, Li, Uitterlinden, André G., Arfan Ikram, M., van Duijn, Cornelia M., Nijsten, Tamar, Walsh, Susan, Branicki, Wojciech, Wang, Sijia ... Kayser, Manfred (2018). Meta-analysis of genome-wide association studies identifies 8 novel loci involved in shape variation of human head hair. Human Molecular Genetics, 27 (3), 559-575. doi: 10.1093/hmg/ddx416
2018
Journal Article
Association of whole-genome and NETRIN1 signaling pathway–derived polygenic risk scores for major depressive disorder and white matter microstructure in the UK Biobank
Barbu, Miruna C., Zeng, Yanni, Shen, Xueyi, Cox, Simon R., Clarke, Toni-Kim, Gibson, Jude, Adams, Mark J., Johnstone, Mandy, Haley, Chris S., Lawrie, Stephen M., Deary, Ian J., Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Wray, Naomi R., Ripke, Stephan, Mattheisen, Manuel, Trzaskowski, Maciej, Byrne, Enda M., Abdellaoui, Abdel, Adams, Mark J., Agerbo, Esben, Air, Tracy M., Andlauer, Till F.M., Bacanu, Silviu-Alin, Bækvad-Hansen, Marie, Beekman, Aartjan T.F., Bigdeli, Tim B., Binder, Elisabeth B., Blackwood, Douglas H.R., Bryois, Julien ... Whalley, Heather C. (2018). Association of whole-genome and NETRIN1 signaling pathway–derived polygenic risk scores for major depressive disorder and white matter microstructure in the UK Biobank. Biological Psychiatry: Cognitive Neuroscience and Neuroimaging, 4 (1), 91-100. doi: 10.1016/j.bpsc.2018.07.006
2018
Conference Publication
Psychiatric Liability Genes are Linked to Oscillatory Brain Activity: A Genome-Wide Association Study
Smit, Dirk, Wright, Margareth, Meyers, Jacquelyn, Martin, Nicholas, Ho, Yvonne, Malone, Stephen, Zhang, Jian, Burwell, Scott, Chorlian, David, de Geus, Eco, Denys, Damiaan, Hansell, Narelle, Hottenga, Jouke-Jan, McGue, Matt, van Beijsterveldt, Catharina, Jehanshad, Neda, Thompson, Paul, Whelan, Chris, Medland, Sarah, Porjesz, Bernice, Iacono, William and Boomsma, Dorret (2018). Psychiatric Liability Genes are Linked to Oscillatory Brain Activity: A Genome-Wide Association Study. 73rd Annual Scientific Convention and Meeting of the Society-of-Biological-Psychiatry (SOBP), New York NY United States, 10-12 May 2017. New York NY United States: Elsevier . doi: 10.1016/j.biopsych.2018.02.865
Supervision
Availability
- Honorary Professor Sarah Medland is:
- Available for supervision
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Supervision history
Current supervision
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Doctor Philosophy
Genetic architecture of differences in symptomatology and treatment response in major depressive disorder
Principal Advisor
Other advisors: Professor Nick Martin, Associate Professor Miguel Rentería
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Doctor Philosophy
Unveiling the Complexities of Psychotic Disorders: Enhancing Treatment Safety and Understanding Heterogeneity Through Biomarkers, Genetic Analysis, and Multimodal Data Integration
Principal Advisor
Other advisors: Professor Dan Siskind
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Doctor Philosophy
Genetic and environmental risk factors influencing mood disorders
Principal Advisor
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Doctor Philosophy
Genetic and environmental risk factors influencing mood disorders
Principal Advisor
-
Doctor Philosophy
Statistical Genetic Analyses of Major Depressive Disorder
Associate Advisor
Completed supervision
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2022
Doctor Philosophy
Exploring the influence of genetics and heritability on the heterogeneity of ADHD presentations
Principal Advisor
Other advisors: Professor Naomi Wray
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2021
Doctor Philosophy
Motivated cognition and genetics: A psychological perspective on public understanding of behaviour genetics
Principal Advisor
Other advisors: Professor Fiona Barlow, Dr Lucia Colodro-Conde
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2019
Doctor Philosophy
Evaluation of the obesity paradox in diabetes: a longitudinal case control study
Principal Advisor
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2016
Doctor Philosophy
Forensically Relevant Applications of Genome-Wide Association Studies
Principal Advisor
Other advisors: Professor Nick Martin
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2023
Doctor Philosophy
Embracing Complexity in Psychiatric Genetics: Investigating Heterogeneity and Pleiotropy in Depression and Major Psychiatric Disorders
Associate Advisor
Other advisors: Dr Enda Byrne
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2020
Doctor Philosophy
Genetic influences on substance use behaviour, substance use disorders and psychiatric disorders
Associate Advisor
Other advisors: Professor Naomi Wray, Professor Nick Martin, Dr Lucia Colodro-Conde
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2014
Doctor Philosophy
Mapping the Genetic Architecture of Subcortical Brain Anatomy
Associate Advisor
Other advisors: Professor Nick Martin
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2012
Doctor Philosophy
The genetics of complex human behaviour: Cannabis use, personality, sexuality and mating
Associate Advisor
Other advisors: Professor Nick Martin
Media
Enquiries
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