Overview
Background
Professor Sarah Medland (OAM, FASSA, FAHMS, PhD) is a Psychiatric and Statistical Geneticist working in Neuroimaging and Mental health genetics. Her work bridges Genetics, Psychology, Neuro-Imaging, Health Economics and applied Statistics with a focus on understanding the genetic and environmental contributions to human behaviour and disease. She chairs the genetics working group of the ENIGMA neuroimaging consortium and is an active member of the Psychiatric Genomics Consortium.
Primary Appointment: Coordinator of the Mental Health Research Program and Group Leader (Psychiatric Genetics) QIMR Berghofer Medical Research Institute.
ORCID: 0000-0003-1382-380X
ResearcherID: C-7630-2013
Scopus Author ID: 34571085600
Email: sarah.medland@qimrberghofer.edu.au
Qualifications
2006 PhD (Psychology), University of Queensland
Dean's Award for Outstanding Research Higher Degree Thesis
2000 BA Hons (Psychology), University of Queensland, 2000 (Psychology Double Major, English Minor)
Availability
- Honorary Professor Sarah Medland is:
- Available for supervision
Fields of research
Works
Search Professor Sarah Medland’s works on UQ eSpace
2018
Conference Publication
Psychiatric Liability Genes are Linked to Oscillatory Brain Activity: A Genome-Wide Association Study
Smit, Dirk, Wright, Margareth, Meyers, Jacquelyn, Martin, Nicholas, Ho, Yvonne, Malone, Stephen, Zhang, Jian, Burwell, Scott, Chorlian, David, de Geus, Eco, Denys, Damiaan, Hansell, Narelle, Hottenga, Jouke-Jan, McGue, Matt, van Beijsterveldt, Catharina, Jehanshad, Neda, Thompson, Paul, Whelan, Chris, Medland, Sarah, Porjesz, Bernice, Iacono, William and Boomsma, Dorret (2018). Psychiatric Liability Genes are Linked to Oscillatory Brain Activity: A Genome-Wide Association Study. 73rd Annual Scientific Convention and Meeting of the Society-of-Biological-Psychiatry (SOBP), New York NY United States, 10-12 May 2017. New York NY United States: Elsevier . doi: 10.1016/j.biopsych.2018.02.865
2018
Journal Article
Type I Error Rates and Parameter Bias in Multivariate Behavioral Genetic Models
Verhulst, Brad, Prom-Wormley, Elizabeth, Keller, Matthew, Medland, Sarah and Neale, Michael C. (2018). Type I Error Rates and Parameter Bias in Multivariate Behavioral Genetic Models. Behavior Genetics, 49 (1), 99-111. doi: 10.1007/s10519-018-9942-y
2018
Journal Article
Accuracy of inferred APOE genotypes for a range of genotyping arrays and imputation reference panels
Lupton, Michelle K., Medland, Sarah E., Gordon, Scott D., Goncalves, Tabatha, MacGregor, Stuart, Mackey, David A., Young, Terri L., Duffy, David L., Visscher, Peter M., Wray, Naomi R., Nyholt, Dale R., Bain, Lisa, Ferreira, Manuel A., Henders, Anjali K., Wallace, Leanne, Montgomery, Grant W., Wright, Margaret J. and Martin, Nicholas G. (2018). Accuracy of inferred APOE genotypes for a range of genotyping arrays and imputation reference panels. Journal of Alzheimer's Disease, 64 (1), 49-54. doi: 10.3233/JAD-171104
2018
Journal Article
Subclonal Evolution of Cancer-Related Gene Mutations in p53 Immunopositive Patches in Human Skin
Albibas, Amel A., Rose-Zerilli, Matthew J. J., Lai, Chester, Pengelly, Reuben J., Lockett, Gabrielle A., Theaker, Jeffrey, Ennis, Sarah, Holloway, John W. and Healy, Eugene (2018). Subclonal Evolution of Cancer-Related Gene Mutations in p53 Immunopositive Patches in Human Skin. Journal of Investigative Dermatology, 138 (1), 189-198. doi: 10.1016/j.jid.2017.07.844
2018
Book Chapter
Multisite metaanalysis of image-wide genome-wide associations with morphometry
Jahanshad, Neda, Roshchupkin, Gennady, Faskowitz, Joshua, Hibar, Derrek P., Gutman, Boris A., Adams, Hieab H. H., Niessen, Wiro J., Vernooij, Meike W., Ikram, M. Arfan, Zwiers, Marcel P., Arias-Vasquez, Alejandro, Franke, Barbara, Ing, Alex, Desrivieres, Sylvane, Schumann, Gunter, de Zubicaray, Greig I., McMahon, Katie L., Medland, Sarah E., Wright, Margaret J. and Thompson, Paul M. (2018). Multisite metaanalysis of image-wide genome-wide associations with morphometry. Imaging genetics. (pp. 1-23) edited by Adrian Dalca, Kayhan Batmanghelich, Mert Sabuncu and Li Shen. London, United Kingdom: Academic Press. doi: 10.1016/B978-0-12-813968-4.00001-8
2017
Journal Article
Pathways to depression by age 16 years: Examining trajectories for self-reported psychological and somatic phenotypes across adolescence
Scott, Jan, Davenport, Tracey A., Parker, Richard, Hermens, Daniel F., Lind, Penelope A., Medland, Sarah E., Wright, Margaret J., Martin, Nicholas G., Gillespie, Nathan A. and Hickie, Ian B. (2017). Pathways to depression by age 16 years: Examining trajectories for self-reported psychological and somatic phenotypes across adolescence. Journal of Affective Disorders, 230, 1-6. doi: 10.1016/j.jad.2017.12.007
2017
Journal Article
Genome-wide association studies of a broad spectrum of antisocial behavior
Tielbeek, Jorim J., Johansson, Ada, Polderman, Tinca J.C., Rautiainen, Marja-Riitta, Jansen, Philip, Taylor, Michelle, Tong, Xiaoran, Lu, Qing, Burt, Alexandra S., Tiemeier, Henning, Viding, Essi, Plomin, Robert, Martin, Nicholas G., Heath, Andrew C., Madden, Pamela A.F., Montgomery, Grant, Beaver, Kevin M., Waldman, Irwin, Gelernter, Joel, Kranzler, Henry R., Farrer, Lindsay A., Perry, John R.B., Munafò, Marcus, LoParo, Devon, Paunio, Tiina, Tiihonen, Jari, Mous, Sabine E., Pappa, Irene, De Leeuw, Christiaan ... Broad Antisocial Behavior Consortium (2017). Genome-wide association studies of a broad spectrum of antisocial behavior. JAMA Psychiatry, 74 (12), 1242-1250. doi: 10.1001/jamapsychiatry.2017.3069
2017
Journal Article
Heritability and GWAS analyses of acne in australian adolescent twins
Mina-Vargas, Angela, Colodro-Conde, Lucía, Grasby, Katrina, Zhu, Gu, Gordon, Scott, Medland, Sarah E. and Martin, Nicholas G. (2017). Heritability and GWAS analyses of acne in australian adolescent twins. Twin Research and Human Genetics, 20 (6), 541-549. doi: 10.1017/thg.2017.58
2017
Journal Article
Genome-wide meta-analysis associates HLA-DQA1/DRB1 and LPA and lifestyle factors with human longevity
Joshi, Peter K., Pirastu, Nicola, Kentistou, Katherine A., Fischer, Krista, Hofer, Edith, Schraut, Katharina E., Clark, David W., Nutile, Teresa, Barnes, Catriona L. K., Timmers, Paul R. H. J., Shen, Xia, Gandin, Ilaria, McDaid, Aaron F., Hansen, Thomas Folkmann, Gordon, Scott D., Giulianini, Franco, Boutin, Thibaud S., Abdellaoui, Abdel, Zhao, Wei, Medina-Gomez, Carolina, Bartz, Traci M., Trompet, Stella, Lange, Leslie A., Raffield, Laura, Van Der Spek, Ashley, Galesloot, Tessel E., Proitsi, Petroula, Yanek, Lisa R., Bielak, Lawrence F. ... Wilson, James F. (2017). Genome-wide meta-analysis associates HLA-DQA1/DRB1 and LPA and lifestyle factors with human longevity. Nature Communications, 8 (1) 910, 910. doi: 10.1038/s41467-017-00934-5
2017
Journal Article
Hair Cortisol in Twins: Heritability and Genetic Overlap with Psychological Variables and Stress-System Genes
Rietschel, Liz, Streit, Fabian, Zhu, Gu, McAloney, Kerrie, Frank, Josef, Couvy-Duchesne, Baptiste, Witt, Stephanie H., Binz, Tina M., Bolton, Jennifer L., Hayward, Caroline, Direk, Nese, Anderson, Anna, Huffman, Jennifer, Wilson, James F., Campbell, Harry, Rudan, Igor, Wright, Alan, Hastie, Nicholas, Wild, Sarah H., Velders, Fleur P., Hofman, Albert, Uitterlinden, Andre G., Lahti, Jari, Räikkönen, Katri, Kajantie, Eero, Widen, Elisabeth, Palotie, Aarno, Eriksson, Johan G., Kaakinen, Marika ... Rietschel, Marcella (2017). Hair Cortisol in Twins: Heritability and Genetic Overlap with Psychological Variables and Stress-System Genes. Scientific Reports, 7 (1) 15351, 15351. doi: 10.1038/s41598-017-11852-3
2017
Journal Article
Genetic overlap between attention-deficit/hyperactivity disorder and bipolar disorder: evidence from genome-wide association study meta-analysis
van Hulzen, Kimm J.E., Scholz, Claus J., Franke, Barbara, Ripke, Stephan, Klein, Marieke, McQuillin, Andrew, Sonuga-Barke, Edmund J., Kelsoe, John R., Landén, Mikael, Andreassen, Ole A., Lesch, Klaus-Peter, Weber, Heike, Faraone, Stephen V., Arias-Vasquez, Alejandro, Reif, Andreas, Anney, Richard J.L., Vasquez, Alejandro Arias, Arranz, Maria J., Asherson, Philip, Banaschewski, Tobias J., Bayés, Mònica, Biederman, Joseph, Buitelaar, Jan K., Casas, Miguel, Charach, Alice, Cormand, Bru, Crosbie, Jennifer, Dalsgaard, Søren, Daly, Mark J. ... PGC Bipolar Disorder Working Group (2017). Genetic overlap between attention-deficit/hyperactivity disorder and bipolar disorder: evidence from genome-wide association study meta-analysis. Biological Psychiatry, 82 (9), 634-641. doi: 10.1016/j.biopsych.2016.08.040
2017
Journal Article
Education in twins and their parents across birth cohorts over 100 years: an individual-level pooled analysis of 42-twin cohorts
Silventoinen, Karri, Jelenkovic, Aline, Latvala, Antti, Sund, Reijo, Yokoyama, Yoshie, Ullemar, Vilhelmina, Almqvist, Catarina, Derom, Catherine A., Vlietinck, Robert F., Loos, Ruth J. F., Kandler, Christian, Honda, Chika, Inui, Fujio, Iwatani, Yoshinori, Watanabe, Mikio, Rebato, Esther, Stazi, Maria A., Fagnani, Corrado, Brescianini, Sonia, Hur, Yoon-Mi, Jeong, Hoe-Uk, Cutler, Tessa L., Hopper, John L., Busjahn, Andreas, Saudino, Kimberly J., Ji, Fuling, Ning, Feng, Pang, Zengchang, Rose, Richard J. ... Kaprio, Jaakko (2017). Education in twins and their parents across birth cohorts over 100 years: an individual-level pooled analysis of 42-twin cohorts. Twin Research and Human Genetics, 20 (5), 395-405. doi: 10.1017/thg.2017.49
2017
Journal Article
Human subcortical brain asymmetries in 15,847 people worldwide reveal effects of age and sex
Guadalupe, Tulio, Mathias, Samuel R., vanErp, Theo G. M., Whelan, Christopher D., Zwiers, Marcel P., Abe, Yoshinari, Abramovic, Lucija, Agartz, Ingrid, Andreassen, Ole A., Arias-Vásquez, Alejandro, Aribisala, Benjamin S., Armstrong, Nicola J., Arolt, Volker, Artiges, Eric, Ayesa-Arriola, Rosa, Baboyan, Vatche G., Banaschewski, Tobias, Barker, Gareth, Bastin, Mark E., Baune, Bernhard T., Blangero, John, Bokde, Arun L.W., Boedhoe, Premika S.W., Bose, Anushree, Brem, Silvia, Brodaty, Henry, Bromberg, Uli, Brooks, Samantha, Büchel, Christian ... Francks, Clyde (2017). Human subcortical brain asymmetries in 15,847 people worldwide reveal effects of age and sex. Brain Imaging and Behavior, 11 (5), 1497-1514. doi: 10.1007/s11682-016-9629-z
2017
Journal Article
CNV-association meta-analysis in 191,161 European adults reveals new loci associated with anthropometric traits
Macé, Aurélien, Tuke, Marcus A., Deelen, Patrick, Kristiansson, Kati, Mattsson, Hannele, Nõukas, Margit, Sapkota, Yadav, Schick, Ursula, Porcu, Eleonora, Rüeger, Sina, McDaid, Aaron F., Porteous, David, Winkler, Thomas W., Salvi, Erika, Shrine, Nick, Liu, Xueping, Ang, Wei Q., Zhang, Weihua, Feitosa, Mary F., Venturini, Cristina, Van Der Most, Peter J., Rosengren, Anders, Wood, Andrew R., Beaumont, Robin N., Jones, Samuel E., Ruth, Katherine S., Yaghootkar, Hanieh, Tyrrell, Jessica, Havulinna, Aki S. ... Kutalik, Zoltán (2017). CNV-association meta-analysis in 191,161 European adults reveals new loci associated with anthropometric traits. Nature Communications, 8 (1) 744, 744. doi: 10.1038/s41467-017-00556-x
2017
Journal Article
Developmental Changes Within the Genetic Architecture of Social Communication Behavior: A Multivariate Study of Genetic Variance in Unrelated Individuals
St Pourcain, Beate, Eaves, Lindon J, Ring, Susan M, Fisher, Simon E, Medland, Sarah, Evans, David M and Davey Smith, George (2017). Developmental Changes Within the Genetic Architecture of Social Communication Behavior: A Multivariate Study of Genetic Variance in Unrelated Individuals. Biological psychiatry, 83 (7), 598-606. doi: 10.1016/j.biopsych.2017.09.020
2017
Journal Article
Autoimmunity/inflammation in a monogenic primary immunodeficiency cohort
Rae, William, Ward, Daniel, Mattocks, Christopher J., Gao, Yifang, Pengelly, Reuben J., Patel, Sanjay V., Ennis, Sarah, Faust, Saul N. and Williams, Anthony P. (2017). Autoimmunity/inflammation in a monogenic primary immunodeficiency cohort. Clinical & Translational Immunology, 6 e155. doi: 10.1038/cti.2017.38
2017
Journal Article
Hidden heritability due to heterogeneity across seven populations
Tropf, Felix C., Lee, S Hong, Verweij, Renske M., Stulp, Gert, van der Most, Peter J., de Vlaming, Ronald, Bakshi, Andrew, Briley, Daniel A., Rahal, Charles, Hellpap, Robert, Nyman, Anastasia, Esko, Tõnu, Metspalu, Andres, Medland, Sarah E., Martin, Nicholas G., Barban, Nicola, Snieder, Harold, Robinson, Matthew R. and Mills, Melinda C. (2017). Hidden heritability due to heterogeneity across seven populations. Nature Human Behaviour, 1 (10), 757-765. doi: 10.1038/s41562-017-0195-1
2017
Journal Article
Identification of a bipolar disorder vulnerable gene CHDH at 3p21.1
Chang, Hong, Li, Lingyi, Peng, Tao, Grigoroiu-Serbanescu, Maria, Bergen, Sarah E., Landén, Mikael, Hultman, Christina M., Forstner, Andreas J., Strohmaier, Jana, Hecker, Julian, Schulze, Thomas G., Müller-Myhsok, Bertram, Reif, Andreas, Mitchell, Philip B., Martin, Nicholas G., Cichon, Sven, Nöthen, Markus M., Jamain, Stéphane, Leboyer, Marion, Bellivier, Frank, Etain, Bruno, Kahn, Jean-Pierre, Henry, Chantal, Rietschel, Marcella, Backlund, Lena, Frisén, Louise, Lavebratt, Catharina, Schalling, Martin, Ösby, Urban ... MooDS Consortium (2017). Identification of a bipolar disorder vulnerable gene CHDH at 3p21.1. Molecular Neurobiology, 54 (7), 5166-5176. doi: 10.1007/s12035-016-0041-x
2017
Journal Article
Genome-Wide Association shows that pigmentation genes play a role in skin aging
Law, Matthew H., Medland, Sarah E., Zhu, Gu, Yazar, Seyhan, Vinuela, Ana, Wallace, Leanne, Shekar, Sri Niranjan, Duffy, David L., Bataille, Veronique, Glass, Dan, Spector, Tim D., Wood, Diane, MuTHER Consortium, Gordon, Scott D., Barbour, Julie M., Henders, Anjali K., Hewitt, Alex W., Montgomery, Grant W., Sturm, Richard A., Mackey, David A., Green, Adele C., Martin, Nicholas G. and MacGregor, Stuart (2017). Genome-Wide Association shows that pigmentation genes play a role in skin aging. Journal of Investigative Dermatology, 137 (9), 1887-1894. doi: 10.1016/j.jid.2017.04.026
2017
Other Outputs
Genomic dissection of bipolar disorder and schizophrenia including 28 subphenotypes
Ruderfer, Douglas M, Ripke, Stephan, McQuillin, Andrew, Boocock, James, Stahl, Eli A, Pavlides, Jennifer M Whitehead, Mullins, Niamh, Charney, Alexander W, Ori, Anil P S, Loohuis, Loes M Olde, Domenici, Enrico, Di Florio, Arianna, Papiol, Sergi, Kalman, Janos L., Adolfsson, Rolf, Agartz, Ingrid, Agerbo, Esben, Akil, Huda, Albani, Diego, Albus, Margot, Alda, Martin, Alexander, Madeline, Allardyce, Judith, Alliey-Rodriguez, Ney, Als, Thomas D, Amin, Farooq, Anjorin, Adebayo, Arranz, Maria J, Awasthi, Swapnil ... Kendler, Kenneth S (2017). Genomic dissection of bipolar disorder and schizophrenia including 28 subphenotypes. doi: 10.1101/173435
Supervision
Availability
- Honorary Professor Sarah Medland is:
- Available for supervision
Before you email them, read our advice on how to contact a supervisor.
Supervision history
Current supervision
-
Doctor Philosophy
Genetic architecture of differences in symptomatology and treatment response in major depressive disorder
Principal Advisor
Other advisors: Professor Nick Martin, Associate Professor Miguel Rentería
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Doctor Philosophy
Unveiling the Complexities of Psychotic Disorders: Enhancing Treatment Safety and Understanding Heterogeneity Through Biomarkers, Genetic Analysis, and Multimodal Data Integration
Principal Advisor
Other advisors: Professor Dan Siskind
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Doctor Philosophy
Genetic and environmental risk factors influencing mood disorders
Principal Advisor
-
Doctor Philosophy
Genetic and environmental risk factors influencing mood disorders
Principal Advisor
-
Doctor Philosophy
Statistical Genetic Analyses of Major Depressive Disorder
Associate Advisor
Completed supervision
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2022
Doctor Philosophy
Exploring the influence of genetics and heritability on the heterogeneity of ADHD presentations
Principal Advisor
Other advisors: Professor Naomi Wray
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2021
Doctor Philosophy
Motivated cognition and genetics: A psychological perspective on public understanding of behaviour genetics
Principal Advisor
Other advisors: Professor Fiona Barlow, Dr Lucia Colodro-Conde
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2019
Doctor Philosophy
Evaluation of the obesity paradox in diabetes: a longitudinal case control study
Principal Advisor
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2016
Doctor Philosophy
Forensically Relevant Applications of Genome-Wide Association Studies
Principal Advisor
Other advisors: Professor Nick Martin
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2023
Doctor Philosophy
Embracing Complexity in Psychiatric Genetics: Investigating Heterogeneity and Pleiotropy in Depression and Major Psychiatric Disorders
Associate Advisor
Other advisors: Dr Enda Byrne
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2020
Doctor Philosophy
Genetic influences on substance use behaviour, substance use disorders and psychiatric disorders
Associate Advisor
Other advisors: Professor Naomi Wray, Professor Nick Martin, Dr Lucia Colodro-Conde
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2014
Doctor Philosophy
Mapping the Genetic Architecture of Subcortical Brain Anatomy
Associate Advisor
Other advisors: Professor Nick Martin
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2012
Doctor Philosophy
The genetics of complex human behaviour: Cannabis use, personality, sexuality and mating
Associate Advisor
Other advisors: Professor Nick Martin
Media
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