Overview
Background
Professor Sarah Medland (OAM, FASSA, FAHMS, PhD) is a Psychiatric and Statistical Geneticist working in Neuroimaging and Mental health genetics. Her work bridges Genetics, Psychology, Neuro-Imaging, Health Economics and applied Statistics with a focus on understanding the genetic and environmental contributions to human behaviour and disease. She chairs the genetics working group of the ENIGMA neuroimaging consortium and is an active member of the Psychiatric Genomics Consortium.
Primary Appointment: Coordinator of the Mental Health Research Program and Group Leader (Psychiatric Genetics) QIMR Berghofer Medical Research Institute.
ORCID: 0000-0003-1382-380X
ResearcherID: C-7630-2013
Scopus Author ID: 34571085600
Email: sarah.medland@qimrberghofer.edu.au
Qualifications
2006 PhD (Psychology), University of Queensland
Dean's Award for Outstanding Research Higher Degree Thesis
2000 BA Hons (Psychology), University of Queensland, 2000 (Psychology Double Major, English Minor)
Availability
- Honorary Professor Sarah Medland is:
- Available for supervision
Fields of research
Works
Search Professor Sarah Medland’s works on UQ eSpace
2019
Conference Publication
Genetic risk for depression and treatment response in the Australian genetics of depression study
Byrne, Enda, Medland, Sarah E., Hickie, Ian, Martin, Nicholas G. and Wray, Naomi (2019). Genetic risk for depression and treatment response in the Australian genetics of depression study. 27th World Congress of Psychiatric Genetics (WCPG), Los Angeles, CA, United States, 26-31 October 2019. Amsterdam, The Netherlands: Elsevier . doi: 10.1016/j.euroneuro.2019.07.109
2019
Conference Publication
A direct test of the diathesis-stress model for depression
Conde, Lucia Colodro, Couvy-Duchesne, Baptiste, Zhu, Gu, Coventry, William, Byrne, Enda, Gordon, Scott, Wright, Margaret, Montgomery, Grant, Madden, Pamela, Ripke, Stephan, Eaves, Lindon, Heath, Andrew, Wray, Naomi, Medland, Sarah E. and Martin, Nick (2019). A direct test of the diathesis-stress model for depression. 25th World Congress of Psychiatric Genetics (WCPG), Orlando, FL United States, 13-17 October 2017. Amsterdam, Netherlands: Elsevier. doi: 10.1016/j.euroneuro.2017.08.045
2019
Conference Publication
Educational attainment polygenic risk scores predict surface area of cortical regions important for language and memory
Mitchell, Brittany, Partida, Gabriel Cuellar, Grasby, Katrina, Strike, Lachlan, Thompson, Paul, Medland, Sarah, Martin, Nicholas, Wright, Margaret and Renteria, Miguel (2019). Educational attainment polygenic risk scores predict surface area of cortical regions important for language and memory. 49th Annual Meeting of the Behavior Genetics Association (BGA), Stockholm, Sweden, 26-29 June, 2019. New York, NY, United States: Springer New York LLC. doi: 10.1007/s10519-019-09973-8
2019
Journal Article
Twenty-Five and Up (25Up) Study: A New Wave of the Brisbane Longitudinal Twin Study
Mitchell, Brittany L., Campos, Adrian I., Rentería, Miguel E., Parker, Richard, Sullivan, Lenore, McAloney, Kerrie, Couvy-Duchesne, Baptiste, Medland, Sarah E., Gillespie, Nathan A., Scott, Jan, Zietsch, Brendan P., Lind, Penelope A., Martin, Nicholas G. and Hickie, Ian B. (2019). Twenty-Five and Up (25Up) Study: A New Wave of the Brisbane Longitudinal Twin Study. Twin Research and Human Genetics, 22 (03) PII S1832427419000276, 154-163. doi: 10.1017/thg.2019.27
2019
Conference Publication
A cross-country, cross-reporter twin study of oppositional defiant disorder
Grasby, Katrina, Colodro-Conde, Lucia, Morosoli, Jose J., Middeldorp, Christel, van Beijsterveldt, Toos, Boomsma, Dorret, Martin, Nicholas, Bartels, Meike and Medland, Sarah (2019). A cross-country, cross-reporter twin study of oppositional defiant disorder. 49th Annual Meeting of the Behavior Genetics Association (BGA), Stockholm, Sweden, 26-29 June, 2019. New York, NY, United States: Springer New York LLC. doi: 10.1007/s10519-019-09973-8
2019
Conference Publication
Exploring the heterogeneity of depression: stressful life events and depressive symptoms
Conde, Lucia Colodro, Couvy-Duchesne, Baptiste, Byrne, Enda, Campos, Adrian, Martin, Nick and Medland, Sarah (2019). Exploring the heterogeneity of depression: stressful life events and depressive symptoms. 27th World Congress of Psychiatric Genetics (WCPG), Los Angeles, CA, United States, 26-31 October 2019. Amsterdam, The Netherlands: Elsevier . doi: 10.1016/j.euroneuro.2019.08.109
2019
Conference Publication
Genomic structural equation models of major depression symptoms
Adams, Mark, Grotzinger, Andrew, Jermy, Bradley, Thorp, Jackson, Nivard, Michel, Byrne, Enda, Hickie, Ian, Martin, Nick, Medland, Sarah, Wray, Naomi, Tucker-Drob, Elliot, Lewis, Cathryn, Derks, Eske and McIntosh, Andrew (2019). Genomic structural equation models of major depression symptoms. 27th World Congress of Psychiatric Genetics (WCPG), Los Angeles, CA, United States, 26-31 October 2019. Amsterdam, The Netherlands: Elsevier. doi: 10.1016/j.euroneuro.2019.08.042
2019
Conference Publication
Examining the shared genetics between educational attainment and depression: results from the Australian Genetics of Depression Study
Mitchell, Brittany, Renteria, Miguel E., Byrne, Enda, Conde, Lucia Colodro, Han, Xikun, Medland, Sarah E., Wray, Naomi and Martin, Nick (2019). Examining the shared genetics between educational attainment and depression: results from the Australian Genetics of Depression Study. 27th World Congress of Psychiatric Genetics, Los Angeles, United States, 26-31 October 2019. Amsterdam, Netherlands: Elsevier. doi: 10.1016/j.euroneuro.2019.07.172
2019
Journal Article
Half the genetic variance in vitamin D concentration is shared with skin colour and sun exposure genes
Mitchell, Brittany L., Zhu, Gu, Medland, Sarah E., Renteria, Miguel. E., Eyles, Darryl W., Grasby, Katrina L., McGrath, John J. and Martin, Nicholas G. (2019). Half the genetic variance in vitamin D concentration is shared with skin colour and sun exposure genes. Behavior Genetics, 49 (4), 386-398. doi: 10.1007/s10519-019-09954-x
2019
Conference Publication
Schizophrenia and urban living: a study on half a million people from three countries
Conde, Lucia Colodro, Couvy-Duchesne, Baptiste, Whitfield, John, Streit, Fabian, Yengo, Loic, Trzaskowski, Maciej, de Zeeuw, Eveline, Nivard, Michel, Whiteman, David, Boomsma, Dorret, Yang, Jian, Rietschel, Marcella, McGrath, John, Medland, Sarah E. and Martin, Nick (2019). Schizophrenia and urban living: a study on half a million people from three countries. 26th World Congress of Psychiatric Genetics (WCPG), Glasgow, Scotland, 11-15 October 2018. Amsterdam, Netherlands: Elsevier. doi: 10.1016/j.euroneuro.2018.08.059
2018
Journal Article
Transancestral GWAS of alcohol dependence reveals common genetic underpinnings with psychiatric disorders
Walters, Raymond K., Polimanti, Renato, Johnson, Emma C., McClintick, Jeanette N., Adams, Mark J., Adkins, Amy E., Aliev, Fazil, Bacanu, Silviu-Alin, Batzler, Anthony, Bertelsen, Sarah, Biernacka, Joanna M., Bigdeli, Tim B., Chen, Li-Shiun, Clarke, Toni-Kim, Chou, Yi-Ling, Degenhardt, Franziska, Docherty, Anna R., Edwards, Alexis C., Fontanillas, Pierre, Foo, Jerome C., Fox, Louis, Frank, Josef, Giegling, Ina, Gordon, Scott, Hack, Laura M., Hartmann, Annette M., Hartz, Sarah M., Heilmann-Heimbach, Stefanie, Herms, Stefan ... Agrawal, Arpana (2018). Transancestral GWAS of alcohol dependence reveals common genetic underpinnings with psychiatric disorders. Nature Neuroscience, 21 (12), 1656-1669. doi: 10.1038/s41593-018-0275-1
2018
Journal Article
A fast method for estimating statistical power of multivariate GWAS in real case scenarios: examples from the field of imaging genetics
Couvy-Duchesne, Baptiste, Strike, Lachlan T., McMahon, Katie L., de Zubicaray, Greig I., Thompson, Paul M., Martin, Nicholas G., Medland, Sarah E. and Wright, Margaret J. (2018). A fast method for estimating statistical power of multivariate GWAS in real case scenarios: examples from the field of imaging genetics. Behavior Genetics, 49 (1), 112-121. doi: 10.1007/s10519-018-9936-9
2018
Journal Article
Genome-wide association meta-analysis of age at first cannabis use
Minică, Camelia C., Verweij, Karin J. H., van der Most, Peter J., Mbarek, Hamdi, Bernard, Manon, van Eijk, Kristel R., Lind, Penelope A., Liu, Meng Zhen, Maciejewski, Dominique F., Palviainen, Teemu, Sánchez-Mora, Cristina, Sherva, Richard, Taylor, Michelle, Walters, Raymond K., Abdellaoui, Abdel, Bigdeli, Timothy B., Branje, Susan J. T., Brown, Sandra A., Casas, Miguel, Corley, Robin P., Smith, George Davey, Davies, Gareth E., Ehli, Erik A., Farrer, Lindsay, Fedko, Iryna O., Garcia-Martínez, Iris, Gordon, Scott D., Hartman, Catharina A., Heath, Andrew C. ... Derks, Eske M. (2018). Genome-wide association meta-analysis of age at first cannabis use. Addiction, 113 (11), 2073-2086. doi: 10.1111/add.14368
2018
Journal Article
Towards broadening Forensic DNA Phenotyping beyond pigmentation: Improving the prediction of head hair shape from DNA
Pośpiech, Ewelina, Chen, Yan, Kukla-Bartoszek, Magdalena, Breslin, Krystal, Aliferi, Anastasia, Andersen, Jeppe D., Ballard, David, Chaitanya, Lakshmi, Freire-Aradas, Ana, van der Gaag, Kristiaan J., Girón-Santamaría, Lorena, Gross, Theresa E., Gysi, Mario, Huber, Gabriela, Mosquera-Miguel, Ana, Muralidharan, Charanya, Skowron, Małgorzata, Carracedo, Ángel, Haas, Cordula, Morling, Niels, Parson, Walther, Phillips, Christopher, Schneider, Peter M., Sijen, Titia, Syndercombe-Court, Denise, Vennemann, Marielle, Wu, Sijie, Xu, Shuhua, Jin, Li ... EUROFORGEN NoE Consortium (2018). Towards broadening Forensic DNA Phenotyping beyond pigmentation: Improving the prediction of head hair shape from DNA. Forensic Science International: Genetics, 37, 241-251. doi: 10.1016/j.fsigen.2018.08.017
2018
Journal Article
Applying polygenic risk scoring for psychiatric disorders to a large family with bipolar disorder and major depressive disorder
de Jong, Simone, Abdalla Diniz, Mateus Jose, Saloma, Andiara, Gadelha, Ary, Santoro, Marcos L., Ota, Vanessa K., Noto, Cristiano, Curtis, Charlesg, Newhouse, Stephen J., Patel, Hamel, Hall, Lynsey S., O'Reilly, Paul F., Belangero, Sintia, Bressan, Rodrigo A., Breen, Gerome, Wray, Naomi R., Ripke, Stephan, Mattheisen, Manuel, Trzaskowski, Maciej, Byrne, Enda M., Abdellaoui, Abdel, Adams, Mark J., Agerbo, Esben, Air, Tracy M., Andlauer, Till F. M., Bacanu, Silviu-Alin, Baekvad-Hansen, Marie, Beekman, Aartjan T. F., Bigdeli, Tim B. ... Major Depressive Disorder and Bipolar Disorder Working Groups of the Psychiatric Genomics Consortium (2018). Applying polygenic risk scoring for psychiatric disorders to a large family with bipolar disorder and major depressive disorder. Communications Biology, 1 (163) 163. doi: 10.1038/s42003-018-0155-y
2018
Journal Article
Mutations in <i>TYR</i> and <i>OCA2</i> associated with oculocutaneous albinism in Pakistani families
Arshad, Muhammad Waqar, Harlalka, Gaurav V., Lin, Siying, D'Atri, Ilaria, Mehmood, Sarmad, Shakil, Muhammad, Hassan, Muhammad Jawad, Chioza, Barry A., Self, Jay E., Ennis, Sarah, O'Gorman, Luke, Norman, Chelsea, Aman, Tahir, Ali, Shaheer Sabz, Kaul, Haiba, Baple, Emma L., Crosby, Andrew H., Ullah, Muhammad Ikram and Shabbir, Muhammad Imran (2018). Mutations in TYR and OCA2 associated with oculocutaneous albinism in Pakistani families. Meta Gene, 17, 48-55. doi: 10.1016/j.mgene.2018.03.007
2018
Journal Article
The genetic relationship between psychological distress, somatic distress, affective disorders, and substance use in young Australian adults: a multivariate twin study
Chang, Lun-Hsien, Couvy-Duchesne, Baptiste, Medland, Sarah E., Gillespie, Nathan A., Hickie, Ian B., Parker, Richard and Martin, Nicholas G. (2018). The genetic relationship between psychological distress, somatic distress, affective disorders, and substance use in young Australian adults: a multivariate twin study. Twin Research and Human Genetics, 21 (5), 347-360. doi: 10.1017/thg.2018.33
2018
Journal Article
Association of current and former smoking with body mass index: a study of smoking discordant twin pairs from 21 twin cohorts
Piirtola, Maarit, Jelenkovic, Aline, Latvala, Antti, Sund, Reijo, Honda, Chika, Inui, Fujio, Watanabe, Mikio, Tomizawa, Rie, Iwatani, Yoshinori, Ordoñana, Juan R., Sánchez-Romera, Juan F., Colodro-Conde, Lucia, Tarnoki, Adam D., Tarnoki, David L., Martin, Nicholas G., Montgomery, Grant W., Medland, Sarah E., Rasmussen, Finn, Tynelius, Per, Tan, Qihua, Zhang, Dongfeng, Pang, Zengchang, Rebato, Esther, Stazi, Maria A., Fagnani, Corrado, Brescianini, Sonia, Busjahn, Andreas, Harris, Jennifer R., Brandt, Ingunn ... Silventoinen, Karri (2018). Association of current and former smoking with body mass index: a study of smoking discordant twin pairs from 21 twin cohorts. PLoS One, 13 (7) e0200140, e0200140. doi: 10.1371/journal.pone.0200140
2018
Conference Publication
The contribution of common population variants to hypomorphic oculocutaneous albinism phenotypes: a novel tri-allelic <i>TYR</i> genotype
Norman, Chelsea Sarah, O'Gorman, Luke, Gibson, Jane, Pengelly, Reuben J., Baralle, Diana, Ratnayaka, J. Arjuna, Ennis, Sarah and Self, James E. (2018). The contribution of common population variants to hypomorphic oculocutaneous albinism phenotypes: a novel tri-allelic TYR genotype. Annual Meeting of the Association-for-Research-in-Vision-and-Ophthalmology (ARVO), Honolulu Hi, Apr 21-May 03, 2018. ROCKVILLE: ASSOC RESEARCH VISION OPHTHALMOLOGY INC.
2018
Journal Article
Significant concordance of genetic variation that increases both the risk for obsessive-compulsive disorder and the volumes of the nucleus accumbens and putamen
Hibar, Derrek P., Cheung, Joshua W., Medland, Sarah E., Mufford, Mary S., Jahanshad, Neda, Dalvie, Shareefa, Ramesar, Raj, Stewart, Evelyn, Van Den Heuvel, Odile A., Pauls, David L., Knowles, James A., Stein, Dan J. and Thompson, Paul M. (2018). Significant concordance of genetic variation that increases both the risk for obsessive-compulsive disorder and the volumes of the nucleus accumbens and putamen. British Journal of Psychiatry, 213 (1), 430-436. doi: 10.1192/bjp.2018.62
Supervision
Availability
- Honorary Professor Sarah Medland is:
- Available for supervision
Looking for a supervisor? Read our advice on how to choose a supervisor.
Supervision history
Current supervision
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Doctor Philosophy
Genetic determinants of treatment outcomes in mental health: harnessing the shared genetic etiology of mental disorders for precision psychiatry.
Principal Advisor
-
Doctor Philosophy
Genetic and environmental risk factors influencing mood disorders
Principal Advisor
-
Master Philosophy
Novel efficient statistical methods for biobank-scale prediction from brain imaging
Principal Advisor
-
Doctor Philosophy
Unveiling the Complexities of Psychotic Disorders: Enhancing Treatment Safety and Understanding Heterogeneity Through Biomarkers, Genetic Analysis, and Multimodal Data Integration
Principal Advisor
Other advisors: Professor Dan Siskind
-
Doctor Philosophy
Genetic architecture of differences in symptomatology and treatment response in major depressive disorder
Associate Advisor
Other advisors: Professor Nick Martin, Associate Professor Miguel Rentería
Completed supervision
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2022
Doctor Philosophy
Exploring the influence of genetics and heritability on the heterogeneity of ADHD presentations
Principal Advisor
Other advisors: Professor Naomi Wray
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2021
Doctor Philosophy
Motivated cognition and genetics: A psychological perspective on public understanding of behaviour genetics
Principal Advisor
Other advisors: Professor Fiona Barlow, Dr Lucia Colodro-Conde
-
2019
Doctor Philosophy
Evaluation of the obesity paradox in diabetes: a longitudinal case control study
Principal Advisor
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2016
Doctor Philosophy
Forensically Relevant Applications of Genome-Wide Association Studies
Principal Advisor
Other advisors: Professor Nick Martin
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2023
Doctor Philosophy
Embracing Complexity in Psychiatric Genetics: Investigating Heterogeneity and Pleiotropy in Depression and Major Psychiatric Disorders
Associate Advisor
Other advisors: Dr Enda Byrne
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2020
Doctor Philosophy
Genetic influences on substance use behaviour, substance use disorders and psychiatric disorders
Associate Advisor
Other advisors: Professor Naomi Wray, Professor Nick Martin, Dr Lucia Colodro-Conde
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2014
Doctor Philosophy
Mapping the Genetic Architecture of Subcortical Brain Anatomy
Associate Advisor
Other advisors: Professor Nick Martin
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2012
Doctor Philosophy
The genetics of complex human behaviour: Cannabis use, personality, sexuality and mating
Associate Advisor
Other advisors: Professor Nick Martin
Media
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