Overview
Background
Professor Sarah Medland (OAM, FASSA, FAHMS, PhD) is a Psychiatric and Statistical Geneticist working in Neuroimaging and Mental health genetics. Her work bridges Genetics, Psychology, Neuro-Imaging, Health Economics and applied Statistics with a focus on understanding the genetic and environmental contributions to human behaviour and disease. She chairs the genetics working group of the ENIGMA neuroimaging consortium and is an active member of the Psychiatric Genomics Consortium.
Primary Appointment: Coordinator of the Mental Health Research Program and Group Leader (Psychiatric Genetics) QIMR Berghofer Medical Research Institute.
ORCID: 0000-0003-1382-380X
ResearcherID: C-7630-2013
Scopus Author ID: 34571085600
Email: sarah.medland@qimrberghofer.edu.au
Qualifications
2006 PhD (Psychology), University of Queensland
Dean's Award for Outstanding Research Higher Degree Thesis
2000 BA Hons (Psychology), University of Queensland, 2000 (Psychology Double Major, English Minor)
Availability
- Honorary Professor Sarah Medland is:
- Available for supervision
Fields of research
Works
Search Professor Sarah Medland’s works on UQ eSpace
2021
Journal Article
Analysis of structural brain asymmetries in attention-deficit/hyperactivity disorder in 39 datasets
Postema, Merel C., Hoogman, Martine, Ambrosino, Sara, Asherson, Philip, Banaschewski, Tobias, Bandeira, Cibele E., Baranov, Alexandr, Bau, Claiton H.D., Baumeister, Sarah, Baur-Streubel, Ramona, Bellgrove, Mark A., Biederman, Joseph, Bralten, Janita, Brandeis, Daniel, Brem, Silvia, Buitelaar, Jan K., Busatto, Geraldo F., Castellanos, Francisco X., Cercignani, Mara, Chaim-Avancini, Tiffany M., Chantiluke, Kaylita C., Christakou, Anastasia, Coghill, David, Conzelmann, Annette, Cubillo, Ana I., Cupertino, Renata B., de Zeeuw, Patrick, Doyle, Alysa E., Durston, Sarah ... Francks, Clyde (2021). Analysis of structural brain asymmetries in attention-deficit/hyperactivity disorder in 39 datasets. Journal of Child Psychology and Psychiatry and Allied Disciplines, 62 (10) jcpp.13396, 1202-1219. doi: 10.1111/jcpp.13396
2021
Journal Article
Large-scale collaboration in ENIGMA-EEG: A perspective on the meta-analytic approach to link neurological and psychiatric liability genes to electrophysiological brain activity
Smit, Dirk J. A., Andreassen, Ole A., Boomsma, Dorret I., Burwell, Scott J., Chorlian, David B., de Geus, Eco J. C., Elvsåshagen, Torbjørn, Gordon, Reyna L., Harper, Jeremy, Hegerl, Ulrich, Hensch, Tilman, Iacono, William G., Jawinski, Philippe, Jönsson, Erik G., Luykx, Jurjen J., Magne, Cyrille L., Malone, Stephen M., Medland, Sarah E., Meyers, Jacquelyn L., Moberget, Torgeir, Porjesz, Bernice, Sander, Christian, Sisodiya, Sanjay M., Thompson, Paul M., van Beijsterveldt, Catharina E. M., van Dellen, Edwin, Via, Marc and Wright, Margaret J. (2021). Large-scale collaboration in ENIGMA-EEG: A perspective on the meta-analytic approach to link neurological and psychiatric liability genes to electrophysiological brain activity. Brain and Behavior, 11 (8) e02188, e02188. doi: 10.1002/brb3.2188
2021
Journal Article
Investigating the causal nature of the relationship of subcortical brain volume with smoking and alcohol use
Logtenberg, Emma, Overbeek, Martin F., Pasman, Joëlle A., Abdellaoui, Abdel, Luijten, Maartje, Van Holst, Ruth J., Vink, Jacqueline M., Denys, Damiaan, Medland, Sarah E., Verweij, Karin J. H. and Treur, Jorien L. (2021). Investigating the causal nature of the relationship of subcortical brain volume with smoking and alcohol use. British Journal of Psychiatry, 221 (1) PII S0007125021000817, 1-9. doi: 10.1192/bjp.2021.81
2021
Journal Article
Growth failure is rare in a contemporary cohort of paediatric inflammatory bowel disease patients
Ashton, James J., Green, Zachary, Young, Aneurin, Borca, Florina, Coelho, Tracy, Batra, Akshay, Afzal, Nadeem A., Ennis, Sarah, Johnson, Mark J. and Beattie, R. Mark (2021). Growth failure is rare in a contemporary cohort of paediatric inflammatory bowel disease patients. Acta Paediatrica, 110 (1), 326-334. doi: 10.1111/apa.15383
2020
Journal Article
Ten years of enhancing neuro-imaging genetics through meta-analysis: an overview from the ENIGMA Genetics Working Group
Medland, Sarah E., Grasby, Katrina L., Jahanshad, Neda, Painter, Jodie N., Colodro-Conde, Lucía, Bralten, Janita, Hibar, Derrek P., Lind, Penelope A., Pizzagalli, Fabrizio, Thomopoulos, Sophia I., Stein, Jason L., Franke, Barbara, Martin, Nicholas G. and Thompson, Paul M. (2020). Ten years of enhancing neuro-imaging genetics through meta-analysis: an overview from the ENIGMA Genetics Working Group. Human Brain Mapping, 43 (1), 292-299. doi: 10.1002/hbm.25311
2020
Journal Article
The evolutionary history of common genetic variants influencing human cortical surface area
Tilot, Amanda K., Khramtsova, Ekaterina A., Liang, Dan, Grasby, Katrina L., Jahanshad, Neda, Painter, Jodie, Colodro-Conde, Lucía, Bralten, Janita, Hibar, Derrek P., Lind, Penelope A., Liu, Siyao, Brotman, Sarah M., Thompson, Paul M., Medland, Sarah E., Macciardi, Fabio, Stranger, Barbara E., Davis, Lea K., Fisher, Simon E. and Stein, Jason L. (2020). The evolutionary history of common genetic variants influencing human cortical surface area. Cerebral Cortex, 31 (4), 1873-1887. doi: 10.1093/cercor/bhaa327
2020
Journal Article
Genetic and environmental variation in educational attainment: an individual-based analysis of 28 twin cohorts
Silventoinen, Karri, Jelenkovic, Aline, Sund, Reijo, Latvala, Antti, Honda, Chika, Inui, Fujio, Tomizawa, Rie, Watanabe, Mikio, Sakai, Norio, Rebato, Esther, Busjahn, Andreas, Tyler, Jessica, Hopper, John L., Ordoñana, Juan R., Sánchez-Romera, Juan F., Colodro-Conde, Lucia, Calais-Ferreira, Lucas, Oliveira, Vinicius C., Ferreira, Paulo H., Medda, Emanuela, Nisticò, Lorenza, Toccaceli, Virgilia, Derom, Catherine A., Vlietinck, Robert F., Loos, Ruth J. F., Siribaddana, Sisira H., Hotopf, Matthew, Sumathipala, Athula, Rijsdijk, Fruhling ... Kaprio, Jaakko (2020). Genetic and environmental variation in educational attainment: an individual-based analysis of 28 twin cohorts. Scientific Reports, 10 (1) 12681, 12681. doi: 10.1038/s41598-020-69526-6
2020
Journal Article
The genetic architecture of sporadic and multiple consecutive miscarriage
Laisk, Triin, Soares, Ana Luiza G., Ferreira, Teresa, Painter, Jodie N., Censin, Jenny C., Laber, Samantha, Bacelis, Jonas, Chen, Chia-Yen, Lepamets, Maarja, Lin, Kuang, Liu, Siyang, Millwood, Iona Y., Ramu, Avinash, Southcombe, Jennifer, Andersen, Marianne S., Yang, Ling, Becker, Christian M., Børglum, Anders D., Gordon, Scott D., Bybjerg-Grauholm, Jonas, Helgeland, Øyvind, Hougaard, David M., Jin, Xin, Johansson, Stefan, Juodakis, Julius, Kartsonaki, Christiana, Kukushkina, Viktorija, Lind, Penelope A., Metspalu, Andres ... Lindgren, Cecilia M. (2020). The genetic architecture of sporadic and multiple consecutive miscarriage. Nature Communications, 11 (1) 5980, 1-12. doi: 10.1038/s41467-020-19742-5
2020
Journal Article
A large-scale genome-wide association study meta-analysis of cannabis use disorder
Johnson, Emma C., Demontis, Ditte, Thorgeirsson, Thorgeir E., Walters, Raymond K., Polimanti, Renato, Hatoum, Alexander S., Sanchez-Roige, Sandra, Paul, Sarah E., Wendt, Frank R., Clarke, Toni-Kim, Lai, Dongbing, Reginsson, Gunnar W., Zhou, Hang, He, June, Baranger, David A. A., Gudbjartsson, Daniel F., Wedow, Robbee, Adkins, Daniel E., Adkins, Amy E., Alexander, Jeffry, Bacanu, Silviu-Alin, Bigdeli, Tim B., Boden, Joseph, Brown, Sandra A., Bucholz, Kathleen K., Bybjerg-Grauholm, Jonas, Corley, Robin P., Degenhardt, Louisa, Dick, Danielle M. ... Agrawal, Arpana (2020). A large-scale genome-wide association study meta-analysis of cannabis use disorder. The Lancet Psychiatry, 7 (12), 1032-1045. doi: 10.1016/S2215-0366(20)30339-4
2020
Journal Article
Short communication: Self-reported sleep-wake disturbances preceding onset of full-threshold mood and/or psychotic syndromes in community residing adolescents and young adults
Scott, Jan, Byrne, Enda, Medland, Sarah and Hickie, Ian (2020). Short communication: Self-reported sleep-wake disturbances preceding onset of full-threshold mood and/or psychotic syndromes in community residing adolescents and young adults. Journal of Affective Disorders, 277, 592-595. doi: 10.1016/j.jad.2020.08.083
2020
Journal Article
Distinctive features of orbital adipose tissue (OAT) in Graves' Orbitopathy
Zhang, Lei, Evans, Anna, von Ruhland, Chris, Draman, Mohd Shazli, Edkins, Sarah, Vincent, Amy E., Berlinguer-Palmini, Rolando, Rees, D. Aled, Haridas, Anjana S., Morris, Dan, Tee, Andrew R., Ludgate, Marian, Turnbull, Doug M., Karpe, Fredrik and Dayan, Colin M. (2020). Distinctive features of orbital adipose tissue (OAT) in Graves' Orbitopathy. International Journal of Molecular Sciences, 21 (23) 9145, 1-18. doi: 10.3390/ijms21239145
2020
Conference Publication
Symptom-level genetic modelling identifies novel risk loci and unravels the shared genetic architecture of anxiety and depression
Thorp, Jackson G., Campos, Adrian I., Grotzinger, Andrew D., Gerring, Zachary, An, Jiyuan, Ong, Jue-Sheng, Wang, Wei, Shringarpure, Suyash, Byrne, Enda M., MacGregor, Stuart, Martin, Nicholas G., Medland, Sarah E., Middeldorp, Christel M. and Derks, Eske M. (2020). Symptom-level genetic modelling identifies novel risk loci and unravels the shared genetic architecture of anxiety and depression. 50th Annual Meeting of the Behavior-Genetics-Association (BGA), Electr Network, Jun 26, 2020. NEW YORK: SPRINGER.
2020
Conference Publication
Modifiable risk factors and miscarriage: a Mendelian Randomization analysis
Painter, Jodie N., Martin, Nick G. and Medland, Sarah E. (2020). Modifiable risk factors and miscarriage: a Mendelian Randomization analysis. 50th Annual Meeting of the Behavior-Genetics-Association (BGA), Electr Network, Jun 26, 2020. NEW YORK: SPRINGER.
2020
Conference Publication
The relationship between comorbid chronic pain and poorer self-reported antidepressant efficacy is partly mediated by genetics
Campos, Adrián I., Roughan, William H., García-Marin, Luis M., Cuéllar-Partida, Gabriel, Lupton, Michelle K., Hickie, Ian B., Medland, Sarah E., Wray, Naomi R., Byrne, Enda M., Ngo, Trung T., Martin, Nicholas G. and Rentería, Miguel E. (2020). The relationship between comorbid chronic pain and poorer self-reported antidepressant efficacy is partly mediated by genetics. Virtual 2020 World Congress of Psychiatric Genetics (WCPG), Online, 16–22 October 2020.
2020
Journal Article
Comparison of genome-wide association scans for quantitative and observational measures of human hair curvature
Ho, Yvonne Y. W., Mina-Vargas, Angela, Zhu, Gu, Brims, Mark, Mcnevin, Dennis, Montgomery, Grant W., Martin, Nicholas G., Medland, Sarah E. and Painter, Jodie N. (2020). Comparison of genome-wide association scans for quantitative and observational measures of human hair curvature. Twin Research and Human Genetics, 23 (5) PII S183242742000078X, 271-277. doi: 10.1017/thg.2020.78
2020
Journal Article
Genome-wide association study identifies 48 common genetic variants associated with handedness
Cuellar-Partida, Gabriel, Tung, Joyce Y., Eriksson, Nicholas, Albrecht, Eva, Aliev, Fazil, Andreassen, Ole A., Barroso, Inês, Beckmann, Jacques S., Boks, Marco P., Boomsma, Dorret I., Boyd, Heather A., Breteler, Monique M. B., Campbell, Harry, Chasman, Daniel I., Cherkas, Lynn F., Davies, Gail, de Geus, Eco J. C., Deary, Ian J., Deloukas, Panos, Dick, Danielle M., Duffy, David L., Eriksson, Johan G., Esko, Tõnu, Feenstra, Bjarke, Geller, Frank, Gieger, Christian, Giegling, Ina, Gordon, Scott D., Han, Jiali ... Medland, Sarah E. (2020). Genome-wide association study identifies 48 common genetic variants associated with handedness. Nature Human Behaviour, 5 (1), 59-70. doi: 10.1038/s41562-020-00956-y
2020
Journal Article
Genetic correlations and genome-wide associations of cortical structure in general population samples of 22,824 adults
Hofer, Edith, Roshchupkin, Gennady V., Adams, Hieab H. H., Knol, Maria J., Lin, Honghuang, Li, Shuo, Zare, Habil, Ahmad, Shahzad, Armstrong, Nicola J., Satizabal, Claudia L., Bernard, Manon, Bis, Joshua C., Gillespie, Nathan A., Luciano, Michelle, Mishra, Aniket, Scholz, Markus, Teumer, Alexander, Xia, Rui, Jian, Xueqiu, Mosley, Thomas H., Saba, Yasaman, Pirpamer, Lukas, Seiler, Stephan, Becker, James T., Carmichael, Owen, Rotter, Jerome I., Psaty, Bruce M., Lopez, Oscar L., Amin, Najaf ... Hansell, Narelle K. (2020). Genetic correlations and genome-wide associations of cortical structure in general population samples of 22,824 adults. Nature Communications, 11 (1) 4796, 4796. doi: 10.1038/s41467-020-18367-y
2020
Journal Article
Septic shock: a genomewide association study and polygenic risk score analysis
D'Urso, Shannon, Rajbhandari, Dorrilyn, Peach, Elizabeth, De Guzman, Erika, Li, Qiang, Medland, Sarah E., Gordon, Scott D., Martin, Nicholas G., Ligthart, Symen, Brown, Matthew A., Powell, Joseph, McArthur, Colin, Rhodes, Andrew, Meyer, Jason, Finfer, Simon, Myburgh, John, Blumenthal, Antje, Cohen, Jeremy, Venkatesh, Balasubramanian, Cuellar-Partida, Gabriel and Evans, David M. (2020). Septic shock: a genomewide association study and polygenic risk score analysis. Twin Research and Human Genetics, 23 (4) PII S1832427420000602, 204-213. doi: 10.1017/thg.2020.60
2020
Journal Article
Challenges in the diagnosis and discovery of rare genetic disorders using contemporary sequencing technologies
Seaby, Eleanor G. and Ennis, Sarah (2020). Challenges in the diagnosis and discovery of rare genetic disorders using contemporary sequencing technologies. Briefings in Functional Genomics, 19 (4), 243-258. doi: 10.1093/bfgp/elaa009
2020
Journal Article
Cohort profile: the Australian genetics of depression study
Byrne, Enda M., Kirk, Katherine M., Medland, Sarah E., McGrath, John J., Colodro-Conde, Lucia, Parker, Richard, Cross, Simone, Sullivan, Lenore, Statham, Dixie J., Levinson, Douglas F., Licinio, Julio, Wray, Naomi R, Hickie, Ian B. and Martin, Nicholas G. (2020). Cohort profile: the Australian genetics of depression study. BMJ Open, 10 (5) e032580, e032580. doi: 10.1136/bmjopen-2019-032580
Supervision
Availability
- Honorary Professor Sarah Medland is:
- Available for supervision
Looking for a supervisor? Read our advice on how to choose a supervisor.
Supervision history
Current supervision
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Doctor Philosophy
Genetic determinants of treatment outcomes in mental health: harnessing the shared genetic etiology of mental disorders for precision psychiatry.
Principal Advisor
Other advisors: Professor Dan Siskind
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Doctor Philosophy
Genetic and environmental risk factors influencing mood disorders
Principal Advisor
-
Master Philosophy
Novel efficient statistical methods for biobank-scale prediction from brain imaging
Principal Advisor
-
Doctor Philosophy
Unveiling the Complexities of Psychotic Disorders: Enhancing Treatment Safety and Understanding Heterogeneity Through Biomarkers, Genetic Analysis, and Multimodal Data Integration
Principal Advisor
Other advisors: Professor Dan Siskind
-
Doctor Philosophy
Genetic architecture of differences in symptomatology and treatment response in major depressive disorder
Associate Advisor
Other advisors: Honorary Professor Nick Martin, Associate Professor Miguel Rentería
Completed supervision
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2022
Doctor Philosophy
Exploring the influence of genetics and heritability on the heterogeneity of ADHD presentations
Principal Advisor
Other advisors: Professor Naomi Wray
-
2021
Doctor Philosophy
Motivated cognition and genetics: A psychological perspective on public understanding of behaviour genetics
Principal Advisor
Other advisors: Professor Fiona Barlow, Dr Lucia Colodro-Conde
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2019
Doctor Philosophy
Evaluation of the obesity paradox in diabetes: a longitudinal case control study
Principal Advisor
-
2016
Doctor Philosophy
Forensically Relevant Applications of Genome-Wide Association Studies
Principal Advisor
Other advisors: Honorary Professor Nick Martin
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2023
Doctor Philosophy
Embracing Complexity in Psychiatric Genetics: Investigating Heterogeneity and Pleiotropy in Depression and Major Psychiatric Disorders
Associate Advisor
Other advisors: Dr Enda Byrne
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2020
Doctor Philosophy
Genetic influences on substance use behaviour, substance use disorders and psychiatric disorders
Associate Advisor
Other advisors: Professor Naomi Wray, Honorary Professor Nick Martin, Dr Lucia Colodro-Conde
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2014
Doctor Philosophy
Mapping the Genetic Architecture of Subcortical Brain Anatomy
Associate Advisor
Other advisors: Honorary Professor Nick Martin
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2012
Doctor Philosophy
The genetics of complex human behaviour: Cannabis use, personality, sexuality and mating
Associate Advisor
Other advisors: Honorary Professor Nick Martin
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2011
Doctor Philosophy
Genetic influences on quality of life throughout the life span: Genetic and environmental influences on the variation in and covariation among traits related to quality of life throughout life time and in the aged.
Associate Advisor
Other advisors: Honorary Professor Nick Martin
Media
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