Overview
Background
Professor Sarah Medland (OAM, FASSA, FAHMS, PhD) is a Psychiatric and Statistical Geneticist working in Neuroimaging and Mental health genetics. Her work bridges Genetics, Psychology, Neuro-Imaging, Health Economics and applied Statistics with a focus on understanding the genetic and environmental contributions to human behaviour and disease. She chairs the genetics working group of the ENIGMA neuroimaging consortium and is an active member of the Psychiatric Genomics Consortium.
Primary Appointment: Coordinator of the Mental Health Research Program and Group Leader (Psychiatric Genetics) QIMR Berghofer Medical Research Institute.
ORCID: 0000-0003-1382-380X
ResearcherID: C-7630-2013
Scopus Author ID: 34571085600
Email: sarah.medland@qimrberghofer.edu.au
Qualifications
2006 PhD (Psychology), University of Queensland
Dean's Award for Outstanding Research Higher Degree Thesis
2000 BA Hons (Psychology), University of Queensland, 2000 (Psychology Double Major, English Minor)
Availability
- Honorary Professor Sarah Medland is:
- Available for supervision
Fields of research
Works
Search Professor Sarah Medland’s works on UQ eSpace
2017
Other Outputs
Genome-wide association study identifies 30 Loci Associated with Bipolar Disorder
Stahl, Eli A, Breen, Gerome, Forstner, Andreas J, McQuillin, Andrew, Ripke, Stephan, Trubetskoy, Vassily, Mattheisen, Manuel, Wang, Yunpeng, Coleman, Jonathan R I, Gaspar, Héléna A, de Leeuw, Christiaan A, Steinberg, Stacy, Pavlides, Jennifer M Whitehead, Trzaskowski, Maciej, Pers, Tune H, Holmans, Peter A, Abbott, Liam, Agerbo, Esben, Akil, Huda, Albani, Diego, Alliey-Rodriguez, Ney, Als, Thomas D, Anjorin, Adebayo, Antilla, Verneri, Awasthi, Swapnil, Badner, Judith A, Bækvad-Hansen, Marie, Barchas, Jack D, Bass, Nicholas ... Sklar, Pamela (2017). Genome-wide association study identifies 30 Loci Associated with Bipolar Disorder. doi: 10.1101/173062
2017
Journal Article
Neuroticism and the Overlap between Autistic and ADHD Traits: Findings from a Population Sample of Young Adult Australian Twins
Park, Shin-Ho, Guastella, Adam J., Lynskey, Michael, Agrawal, Arpana, Constantino, John N., Medland, Sarah E., Song, Yun Ju C., Martin, Nicholas G. and Colodro-Conde, Lucía (2017). Neuroticism and the Overlap between Autistic and ADHD Traits: Findings from a Population Sample of Young Adult Australian Twins. Twin Research and Human Genetics, 20 (4), 319-329. doi: 10.1017/thg.2017.38
2017
Journal Article
Differences in genetic and environmental variation in adult BMI by sex, age, time period, and region: an individual-based pooled analysis of 40 twin cohorts
Silventoinen, Karri, Jelenkovic, Aline, Sund, Reijo, Yokoyama, Yoshie, Hur, Yoon-Mi, Cozen, Wendy, Hwang, Amie E., Mack, Thomas M., Honda, Chika, Inui, Fujio, Iwatani, Yoshinori, Watanabe, Mikio, Tomizawa, Rie, Pietilainen, Kirsi H., Rissanen, Aila, Siribaddana, Sisira H., Hotopf, Matthew, Sumathipala, Athula, Rijsdijk, Fruhling, Tan, Qihua, Zhang, Dongfeng, Pang, Zengchang, Piirtola, Maarit, Aaltonen, Sari, Oncel, Sevgi Y., Aliev, Fazil, Rebato, Esther, Hjelmborg, Jacob B., Christensen, Kaare ... Kaprio, Jaakko (2017). Differences in genetic and environmental variation in adult BMI by sex, age, time period, and region: an individual-based pooled analysis of 40 twin cohorts. American Journal of Clinical Nutrition, 106 (2), 457-466. doi: 10.3945/ajcn.117.153643
2017
Journal Article
A direct test of the diathesis–stress model for depression
Colodro-Conde, L., Couvy-Duchesne, B., Zhu, G., Coventry, W. L., Byrne, E. M., Gordon, S., Wright, M. J., Montgomery, G. W., Madden, P. A. F., Ripke, S., Eaves, L. J., Heath, A. C., Wray, N. R., Medland, S. E. and Martin, N. G. (2017). A direct test of the diathesis–stress model for depression. Molecular Psychiatry, 23 (7), 1590-1596. doi: 10.1038/mp.2017.130
2017
Journal Article
No genetic overlap between circulating iron levels and Alzheimer's disease
Lupton, Michelle K., Benyamin, Beben, Proitsi, Petroula, Nyholt, Dale R., Ferreira, Manuel A., Montgomery, Grant W., Heath, Andrew C., Madden, Pamela A., Medland, Sarah E., Gordon, Scott D., Lovestone, Simon, Tsolaki, Magda, Kloszewska, Iwona, Soininen, Hilkka, Mecocci, Patrizia, Vellas, Bruno, Powell, John F., Bush, Ashley I., Wright, Margaret J., Martin, Nicholas G. and Whitfield, John B. (2017). No genetic overlap between circulating iron levels and Alzheimer's disease. Journal of Alzheimers Disease, 59 (1), 85-99. doi: 10.3233/JAD-170027
2017
Journal Article
Polygenic transmission disequilibrium confirms that common and rare variation act additively to create risk for autism spectrum disorders
Weiner, Daniel J., Wigdor, Emilie M., Ripke, Stephan, Walters, Raymond K., Kosmicki, Jack A., Grove, Jakob, Samocha, Kaitlin E., Goldstein, Jacqueline I., Okbay, Aysu, Bybjerg-Grauholm, Jonas, Werge, Thomas, Hougaard, David M, Taylor, Jacob, Skuse, David, Devlin, Bernie, Anney, Richard, Sanders, Stephan J, Bishop, Somer, Mortensen, Preben Bo, Børglum, Anders D, Smith, George Davey, Daly, Mark J, Robinson, Elise B., Bækvad-Hansen, Marie, Dumont, Ashley, Hansen, Christine, Hansen, Thomas F., Howrigan, Daniel, Mattheisen, Manuel ... iPSYCH-Broad Autism Grp ; Psychiat Genomics Consortium (2017). Polygenic transmission disequilibrium confirms that common and rare variation act additively to create risk for autism spectrum disorders. Nature Genetics, 49 (7), 978-985. doi: 10.1038/ng.3863
2017
Journal Article
Obstetrical, pregnancy and socio-economic predictors for new-onset severe postpartum psychiatric disorders in primiparous women
Meltzer-Brody, S., Maegbaek, M. L., Medland, S. E., Miller, W. C., Sullivan, P. and Munk-Olsen, T. (2017). Obstetrical, pregnancy and socio-economic predictors for new-onset severe postpartum psychiatric disorders in primiparous women. Psychological Medicine, 47 (8), 1427-1441. doi: 10.1017/S0033291716003020
2017
Journal Article
Meta-analysis of GWAS of over 16,000 individuals with autism spectrum disorder highlights a novel locus at 10q24.32 and a significant overlap with schizophrenia
Anney, Richard J. L., Ripke, Stephan, Anttila, Verneri, Grove, Jakob, Holmans, Peter, Huang, Hailiang, Klei, Lambertus, Lee, Phil H., Medland, Sarah E., Neale, Benjamin, Robinson, Elise, Weiss, Lauren A., Zwaigenbaum, Lonnie, Yu, Timothy W., Wittemeyer, Kerstin, Willsey, A.Jeremy, Wijsman, Ellen M., Werge, Thomas, Wassink, Thomas H., Waltes, Regina, Walsh, Christopher A., Wallace, Simon, Vorstman, Jacob A. S., Vieland, Veronica J., Vicente, Astrid M., Vanengeland, Herman, Tsang, Kathryn, Thompson, Ann P., Szatmari, Peter ... The Autism Spectrum Disorders Working Group of The Psychiatric Genomics Consortium (2017). Meta-analysis of GWAS of over 16,000 individuals with autism spectrum disorder highlights a novel locus at 10q24.32 and a significant overlap with schizophrenia. Molecular Autism, 8 (1) 21. doi: 10.1186/s13229-017-0137-9
2017
Journal Article
Subcortical brain structure and suicidal behaviour in major depressive disorder: a meta-analysis from the ENIGMA-MDD working group
Renteria, M. E., Schmaal, L., Hibar, D. P., Couvy-Duchesne, B., Strike, L. T., Mills, N. T., de Zubicaray, G. I., McMahon, K. L., Medland, S. E., Gillespie, N. A., Hatton, S. N., Lagopoulos, J., Veltman, D. J., van der Wee, N., van Erp, T. G. M., Wittfeld, K., Grabe, H. J., Block, A., Hegenscheid, K., Voelzke, H., Veer, I. M., Walter, H., Schnell, K., Schramm, E., Normann, C., Schoepf, D., Konrad, C., Zurowski, B., Godlewska, B. R. ... Hickie, I. B. (2017). Subcortical brain structure and suicidal behaviour in major depressive disorder: a meta-analysis from the ENIGMA-MDD working group. Translational Psychiatry, 7 (5) e1116, e1116-e1116. doi: 10.1038/tp.2017.84
2017
Journal Article
Does the sex of one’s co-twin affect height and BMI in adulthood? A study of dizygotic adult twins from 31 cohorts
Bogl, Leonie H., Jelenkovic, Aline, Vuoksimaa, Eero, Ahrenfeldt, Linda, Pietiläinen, Kirsi H., Stazi, Maria A., Fagnani, Corrado, D’Ippolito, Cristina, Hur, Yoon-Mi, Jeong, Hoe-Uk, Silberg, Judy L., Eaves, Lindon J., Maes, Hermine H., Bayasgalan, Gombojav, Narandalai, Danshiitsoodol, Cutler, Tessa L., Kandler, Christian, Jang, Kerry L., Christensen, Kaare, Skytthe, Axel, Kyvik, Kirsten O., Cozen, Wendy, Hwang, Amie E., Mack, Thomas M., Derom, Catherine A., Vlietinck, Robert F., Nelson, Tracy L., Whitfield, Keith E., Corley, Robin P. ... Kaprio, Jaakko (2017). Does the sex of one’s co-twin affect height and BMI in adulthood? A study of dizygotic adult twins from 31 cohorts. Biology of Sex Differences, 8 (1) 14. doi: 10.1186/s13293-017-0134-x
2017
Journal Article
Subcortical brain volume differences in participants with attention deficit hyperactivity disorder in children and adults: a cross-sectional mega-analysis
Hoogman, Martine, Bralten, Janita, Hibar, Derrek P, Mennes, Maarten, Zwiers, Marcel P, Schweren, Lizanne S J, van Hulzen, Kimm J E, Medland, Sarah E, Shumskaya, Elena, Jahanshad, Neda, Zeeuw, Patrick de, Szekely, Eszter, Sudre, Gustavo, Wolfers, Thomas, Onnink, Alberdingk M H, Dammers, Janneke T, Mostert, Jeanette C, Vives-Gilabert, Yolanda, Kohls, Gregor, Oberwelland, Eileen, Seitz, Jochen, Schulte-Rüther, Martin, Ambrosino, Sara, Doyle, Alysa E, Høvik, Marie F, Dramsdahl, Margaretha, Tamm, Leanne, van Erp, Theo G M, Dale, Anders ... Franke, Barbara (2017). Subcortical brain volume differences in participants with attention deficit hyperactivity disorder in children and adults: a cross-sectional mega-analysis. The Lancet Psychiatry, 4 (4), 310-319. doi: 10.1016/S2215-0366(17)30049-4
2017
Journal Article
Genomic analyses identify hundreds of variants associated with age at menarche and support a role for puberty timing in cancer risk
Day, Felix R., Thompson, Deborah J., Helgason, Hannes, Chasman, Daniel I., Finucane, Hilary, Sulem, Patrick, Ruth, Katherine S., Whalen, Sean, Sarkar, Abhishek K., Albrecht, Eva, Altmaier, Elisabeth, Amini, Marzyeh, Barbieri, Caterina M., Boutin, Thibaud, Campbell, Archie, Demerath, Ellen, Giri, Ayush, He, Chunyan, Hottenga, Jouke J., Karlsson, Robert, Kolcic, Ivana, Loh, Po-Ru, Lunetta, Kathryn L., Mangino, Massimo, Marco, Brumat, McMahon, George, Medland, Sarah E., Nolte, Ilja M., Noordam, Raymond ... Perry, John R. B. (2017). Genomic analyses identify hundreds of variants associated with age at menarche and support a role for puberty timing in cancer risk. Nature Genetics, 49 (6), 834-841. doi: 10.1038/ng.3841
2017
Journal Article
Genetic effects influencing risk for major depressive disorder in China and Europe
Bigdeli, T. B., Ripke, S., Peterson, R. E., Trzaskowski, M., Bacanu, S-A, Abdellaoui, A., Andlauer, T. F. M., Beekman, A. T. F., Berger, K., Blackwood, D. H. R., Boomsma, D. I., Breen, G., Buttenschon, H. N., Byrne, E. M., Cichon, S., Clarke, T-K, Couvy-Duchesne, B., Craddock, N., de Geus, E. J. C., Degenhardt, F., Dunn, E. C., Edwards, A. C., Fanous, A. H., Forstner, A. J., Frank, J., Gill, M., Gordon, S. D., Grabe, H. J., Hamilton, S. P. ... Kendler, K. S. (2017). Genetic effects influencing risk for major depressive disorder in China and Europe. Translational Psychiatry, 7 (3) e1074, e1074-e1074. doi: 10.1038/tp.2016.292
2017
Other Outputs
An epigenome-wide association study of educational attainment (n = 10,767)
Linnér, Richard Karlsson, Marioni, Riccardo E, Rietveld, Cornelius A, Simpkin, Andrew, Davies, Neil M, Watanabe, Kyoko, Armstrong, Nicola J, Auro, Kirsi, Baumbach, Clemens, Bonder, Marc Jan, Buchwald, Jadwiga, Fiorito, Giovanni, Ismail, Khadeeja, Iurato, Stella, Joensuu, Anni, Karell, Pauliina, Kasela, Silva, Lahti, Jari, McRae, Allan F, Mandaviya, Pooja R, Seppälä, Ilkka, Wang, Yunzhang, Baglietto, Laura, Binder, Elisabeth B, Harris, Sarah E, Hodge, Allison M, Horvath, Steve, Hurme, Mikko, Johannesson, Magnus ... Benjamin, Daniel J (2017). An epigenome-wide association study of educational attainment (n = 10,767). doi: 10.1101/114637
2017
Journal Article
Identification of shared risk loci and pathways for bipolar disorder and schizophrenia
Forstner, Andreas J., Hecker, Julian, Hofmann, Andrea, Maaser, Anna, Reinbold, Céline S., Mühleisen, Thomas W., Leber, Markus, Strohmaier, Jana, Degenhardt, Franziska, Treutlein, Jens, Mattheisen, Manuel, Schumacher, Johannes, Streit, Fabian, Meier, Sandra, Herms, Stefan, Hoffmann, Per, Lacour, André, Witt, Stephanie H., Reif, Andreas, Müller-Myhsok, Bertram, Lucae, Susanne, Maier, Wolfgang, Schwarz, Markus, Vedder, Helmut, Kammerer-Ciernioch, Jutta, Pfennig, Andrea, Bauer, Michael, Hautzinger, Martin, Moebus, Susanne ... Nöthen, Markus M. (2017). Identification of shared risk loci and pathways for bipolar disorder and schizophrenia. PLoS ONE, 12 (2) e0171595, e0171595. doi: 10.1371/journal.pone.0171595
2017
Journal Article
Novel genetic loci associated with hippocampal volume
Hibar, Derrek P., Adams, Hieab H. H., Jahanshad, Neda, Chauhan, Ganesh, Stein, Jason L., Hofer, Edith, Renteria, Miguel E., Bis, Joshua C., Arias-Vasquez, Alejandro, Ikram, M. Kamran, Desrivieres, Sylvane, Vernooij, Meike W., Abramovic, Lucija, Alhusaini, Saud, Amin, Najaf, Andersson, Micael, Arfanakis, Konstantinos, Aribisala, Benjamin S., Armstrong, Nicola J., Athanasiu, Lavinia, Axelsson, Tomas, Beecham, Ashley H., Beiser, Alexa, Bernard, Manon, Blanton, Susan H., Bohlken, Marc M., Boks, Marco P., Bralten, Janita, Brickman, Adam M. ... Ikram, M. Arfan (2017). Novel genetic loci associated with hippocampal volume. Nature Communications, 8 (1) 13624, 13624. doi: 10.1038/ncomms13624
2017
Journal Article
Genetic analysis of hyperemesis gravidarum reveals association with intracellular calcium release channel (RYR2)
Fejzo, Marlena Schoenberg, Myhre, Ronny, Colodro-Conde, Lucía, MacGibbon, Kimber W, Sinsheimer, Janet S., Reddy, M. V. Prasad Linga, Pajukanta, Paivi, Nyholt, Dale R., Wright, Margaret J., Martin, Nicholas G., Engel, Stephanie M., Medland, Sarah E., Magnus, Per and Mullin, Patrick M. (2017). Genetic analysis of hyperemesis gravidarum reveals association with intracellular calcium release channel (RYR2). Molecular and Cellular Endocrinology, 439 (C), 308-316. doi: 10.1016/j.mce.2016.09.017
2017
Conference Publication
First GWAS meta-analysis on nausea and vomiting during pregnancy
Conde, Lucia Colodro, Paternoster, Lavinia, Lind, Penelope, Painter, Jodie, Wright, Margie, Montgomery, Grant, Nyholt, Dale and Medland, Sarah E. (2017). First GWAS meta-analysis on nausea and vomiting during pregnancy. 23rd Annual World Congress of Psychiatric Genetics (WCPG), Toronto, Canada, 16-20 October, 2015. Amsterdam, Netherlands: Elsevier BV.
2017
Conference Publication
Heritability of hair cortisol and genetic overlap with psychological variables
Streit, Fabian, Rietschel, Liz, Zhu, Gu, McAloney, Kerrie, Frank, Josef, Couvy-Duchesne, Baptiste, Witt, Stephanie H., Binz, Tina, McGrath, John, Hickie, Ian B., Hansell, Narelle K., Wright, Margaret J., Gillespie, Nathan, Forstner, Andreas J., Schulze, Thomas G., Wüst, Stefan, Nöthen, Markus M., Baumgartner, Markus, Walker, Brian R., Crawford, Andrew A., Conde, Lucia Colodro, Medland, Sarah E., Martin, Nicholas G. and Rietschel, Marcella (2017). Heritability of hair cortisol and genetic overlap with psychological variables. 47th Annual Conference of the International Society of Psychoneuroendocrinology, Zurich, Switzerland, 7-9 September, 2017. OXFORD: Pergamon. doi: 10.1016/j.psyneuen.2017.07.452
2017
Book Chapter
Continuous inflation analysis: a threshold-free method to estimate genetic overlap and boost power in imaging genetics
Hibar, Derrek P., Jahanshad, Neda, Medland, Sarah E. and Thompson, Paul M. (2017). Continuous inflation analysis: a threshold-free method to estimate genetic overlap and boost power in imaging genetics. Imaging Genetics. (pp. 147-162) Kidlington, Oxford, United Kingdom: Elsevier Inc.. doi: 10.1016/B978-0-12-813968-4.00009-2
Supervision
Availability
- Honorary Professor Sarah Medland is:
- Available for supervision
Before you email them, read our advice on how to contact a supervisor.
Supervision history
Current supervision
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Doctor Philosophy
Genetic and environmental risk factors influencing mood disorders
Principal Advisor
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Doctor Philosophy
Genetic and environmental risk factors influencing mood disorders
Principal Advisor
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Doctor Philosophy
Genetic architecture of differences in symptomatology and treatment response in major depressive disorder
Principal Advisor
Other advisors: Professor Nick Martin, Associate Professor Miguel Rentería
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Doctor Philosophy
Unveiling the Complexities of Psychotic Disorders: Enhancing Treatment Safety and Understanding Heterogeneity Through Biomarkers, Genetic Analysis, and Multimodal Data Integration
Principal Advisor
Other advisors: Professor Dan Siskind
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Doctor Philosophy
Statistical Genetic Analyses of Major Depressive Disorder
Associate Advisor
Completed supervision
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2022
Doctor Philosophy
Exploring the influence of genetics and heritability on the heterogeneity of ADHD presentations
Principal Advisor
Other advisors: Professor Naomi Wray
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2021
Doctor Philosophy
Motivated cognition and genetics: A psychological perspective on public understanding of behaviour genetics
Principal Advisor
Other advisors: Professor Fiona Barlow, Dr Lucia Colodro-Conde
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2019
Doctor Philosophy
Evaluation of the obesity paradox in diabetes: a longitudinal case control study
Principal Advisor
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2016
Doctor Philosophy
Forensically Relevant Applications of Genome-Wide Association Studies
Principal Advisor
Other advisors: Professor Nick Martin
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2023
Doctor Philosophy
Embracing Complexity in Psychiatric Genetics: Investigating Heterogeneity and Pleiotropy in Depression and Major Psychiatric Disorders
Associate Advisor
Other advisors: Dr Enda Byrne
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2020
Doctor Philosophy
Genetic influences on substance use behaviour, substance use disorders and psychiatric disorders
Associate Advisor
Other advisors: Professor Naomi Wray, Professor Nick Martin, Dr Lucia Colodro-Conde
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2014
Doctor Philosophy
Mapping the Genetic Architecture of Subcortical Brain Anatomy
Associate Advisor
Other advisors: Professor Nick Martin
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2012
Doctor Philosophy
The genetics of complex human behaviour: Cannabis use, personality, sexuality and mating
Associate Advisor
Other advisors: Professor Nick Martin
Media
Enquiries
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