Overview
Background
Professor Sarah Medland (OAM, FASSA, FAHMS, PhD) is a Psychiatric and Statistical Geneticist working in Neuroimaging and Mental health genetics. Her work bridges Genetics, Psychology, Neuro-Imaging, Health Economics and applied Statistics with a focus on understanding the genetic and environmental contributions to human behaviour and disease. She chairs the genetics working group of the ENIGMA neuroimaging consortium and is an active member of the Psychiatric Genomics Consortium.
Primary Appointment: Coordinator of the Mental Health Research Program and Group Leader (Psychiatric Genetics) QIMR Berghofer Medical Research Institute.
ORCID: 0000-0003-1382-380X
ResearcherID: C-7630-2013
Scopus Author ID: 34571085600
Email: sarah.medland@qimrberghofer.edu.au
Qualifications
2006 PhD (Psychology), University of Queensland
Dean's Award for Outstanding Research Higher Degree Thesis
2000 BA Hons (Psychology), University of Queensland, 2000 (Psychology Double Major, English Minor)
Availability
- Honorary Professor Sarah Medland is:
- Available for supervision
Fields of research
Works
Search Professor Sarah Medland’s works on UQ eSpace
2017
Journal Article
Neuroticism and the Overlap between Autistic and ADHD Traits: Findings from a Population Sample of Young Adult Australian Twins
Park, Shin-Ho, Guastella, Adam J., Lynskey, Michael, Agrawal, Arpana, Constantino, John N., Medland, Sarah E., Song, Yun Ju C., Martin, Nicholas G. and Colodro-Conde, Lucía (2017). Neuroticism and the Overlap between Autistic and ADHD Traits: Findings from a Population Sample of Young Adult Australian Twins. Twin Research and Human Genetics, 20 (4), 319-329. doi: 10.1017/thg.2017.38
2017
Journal Article
A direct test of the diathesis–stress model for depression
Colodro-Conde, L., Couvy-Duchesne, B., Zhu, G., Coventry, W. L., Byrne, E. M., Gordon, S., Wright, M. J., Montgomery, G. W., Madden, P. A. F., Ripke, S., Eaves, L. J., Heath, A. C., Wray, N. R., Medland, S. E. and Martin, N. G. (2017). A direct test of the diathesis–stress model for depression. Molecular Psychiatry, 23 (7), 1590-1596. doi: 10.1038/mp.2017.130
2017
Journal Article
No genetic overlap between circulating iron levels and Alzheimer's disease
Lupton, Michelle K., Benyamin, Beben, Proitsi, Petroula, Nyholt, Dale R., Ferreira, Manuel A., Montgomery, Grant W., Heath, Andrew C., Madden, Pamela A., Medland, Sarah E., Gordon, Scott D., Lovestone, Simon, Tsolaki, Magda, Kloszewska, Iwona, Soininen, Hilkka, Mecocci, Patrizia, Vellas, Bruno, Powell, John F., Bush, Ashley I., Wright, Margaret J., Martin, Nicholas G. and Whitfield, John B. (2017). No genetic overlap between circulating iron levels and Alzheimer's disease. Journal of Alzheimers Disease, 59 (1), 85-99. doi: 10.3233/JAD-170027
2017
Journal Article
Polygenic transmission disequilibrium confirms that common and rare variation act additively to create risk for autism spectrum disorders
Weiner, Daniel J., Wigdor, Emilie M., Ripke, Stephan, Walters, Raymond K., Kosmicki, Jack A., Grove, Jakob, Samocha, Kaitlin E., Goldstein, Jacqueline I., Okbay, Aysu, Bybjerg-Grauholm, Jonas, Werge, Thomas, Hougaard, David M, Taylor, Jacob, Skuse, David, Devlin, Bernie, Anney, Richard, Sanders, Stephan J, Bishop, Somer, Mortensen, Preben Bo, Børglum, Anders D, Smith, George Davey, Daly, Mark J, Robinson, Elise B., Bækvad-Hansen, Marie, Dumont, Ashley, Hansen, Christine, Hansen, Thomas F., Howrigan, Daniel, Mattheisen, Manuel ... iPSYCH-Broad Autism Grp ; Psychiat Genomics Consortium (2017). Polygenic transmission disequilibrium confirms that common and rare variation act additively to create risk for autism spectrum disorders. Nature Genetics, 49 (7), 978-985. doi: 10.1038/ng.3863
2017
Journal Article
Obstetrical, pregnancy and socio-economic predictors for new-onset severe postpartum psychiatric disorders in primiparous women
Meltzer-Brody, S., Maegbaek, M. L., Medland, S. E., Miller, W. C., Sullivan, P. and Munk-Olsen, T. (2017). Obstetrical, pregnancy and socio-economic predictors for new-onset severe postpartum psychiatric disorders in primiparous women. Psychological Medicine, 47 (8), 1427-1441. doi: 10.1017/S0033291716003020
2017
Journal Article
Meta-analysis of GWAS of over 16,000 individuals with autism spectrum disorder highlights a novel locus at 10q24.32 and a significant overlap with schizophrenia
Anney, Richard J. L., Ripke, Stephan, Anttila, Verneri, Grove, Jakob, Holmans, Peter, Huang, Hailiang, Klei, Lambertus, Lee, Phil H., Medland, Sarah E., Neale, Benjamin, Robinson, Elise, Weiss, Lauren A., Zwaigenbaum, Lonnie, Yu, Timothy W., Wittemeyer, Kerstin, Willsey, A.Jeremy, Wijsman, Ellen M., Werge, Thomas, Wassink, Thomas H., Waltes, Regina, Walsh, Christopher A., Wallace, Simon, Vorstman, Jacob A. S., Vieland, Veronica J., Vicente, Astrid M., Vanengeland, Herman, Tsang, Kathryn, Thompson, Ann P., Szatmari, Peter ... The Autism Spectrum Disorders Working Group of The Psychiatric Genomics Consortium (2017). Meta-analysis of GWAS of over 16,000 individuals with autism spectrum disorder highlights a novel locus at 10q24.32 and a significant overlap with schizophrenia. Molecular Autism, 8 (1) 21. doi: 10.1186/s13229-017-0137-9
2017
Journal Article
Subcortical brain structure and suicidal behaviour in major depressive disorder: a meta-analysis from the ENIGMA-MDD working group
Renteria, M. E., Schmaal, L., Hibar, D. P., Couvy-Duchesne, B., Strike, L. T., Mills, N. T., de Zubicaray, G. I., McMahon, K. L., Medland, S. E., Gillespie, N. A., Hatton, S. N., Lagopoulos, J., Veltman, D. J., van der Wee, N., van Erp, T. G. M., Wittfeld, K., Grabe, H. J., Block, A., Hegenscheid, K., Voelzke, H., Veer, I. M., Walter, H., Schnell, K., Schramm, E., Normann, C., Schoepf, D., Konrad, C., Zurowski, B., Godlewska, B. R. ... Hickie, I. B. (2017). Subcortical brain structure and suicidal behaviour in major depressive disorder: a meta-analysis from the ENIGMA-MDD working group. Translational Psychiatry, 7 (5) e1116, e1116-e1116. doi: 10.1038/tp.2017.84
2017
Journal Article
Does the sex of one’s co-twin affect height and BMI in adulthood? A study of dizygotic adult twins from 31 cohorts
Bogl, Leonie H., Jelenkovic, Aline, Vuoksimaa, Eero, Ahrenfeldt, Linda, Pietiläinen, Kirsi H., Stazi, Maria A., Fagnani, Corrado, D’Ippolito, Cristina, Hur, Yoon-Mi, Jeong, Hoe-Uk, Silberg, Judy L., Eaves, Lindon J., Maes, Hermine H., Bayasgalan, Gombojav, Narandalai, Danshiitsoodol, Cutler, Tessa L., Kandler, Christian, Jang, Kerry L., Christensen, Kaare, Skytthe, Axel, Kyvik, Kirsten O., Cozen, Wendy, Hwang, Amie E., Mack, Thomas M., Derom, Catherine A., Vlietinck, Robert F., Nelson, Tracy L., Whitfield, Keith E., Corley, Robin P. ... Kaprio, Jaakko (2017). Does the sex of one’s co-twin affect height and BMI in adulthood? A study of dizygotic adult twins from 31 cohorts. Biology of Sex Differences, 8 (1) 14. doi: 10.1186/s13293-017-0134-x
2017
Journal Article
Subcortical brain volume differences in participants with attention deficit hyperactivity disorder in children and adults: a cross-sectional mega-analysis
Hoogman, Martine, Bralten, Janita, Hibar, Derrek P, Mennes, Maarten, Zwiers, Marcel P, Schweren, Lizanne S J, van Hulzen, Kimm J E, Medland, Sarah E, Shumskaya, Elena, Jahanshad, Neda, Zeeuw, Patrick de, Szekely, Eszter, Sudre, Gustavo, Wolfers, Thomas, Onnink, Alberdingk M H, Dammers, Janneke T, Mostert, Jeanette C, Vives-Gilabert, Yolanda, Kohls, Gregor, Oberwelland, Eileen, Seitz, Jochen, Schulte-Rüther, Martin, Ambrosino, Sara, Doyle, Alysa E, Høvik, Marie F, Dramsdahl, Margaretha, Tamm, Leanne, van Erp, Theo G M, Dale, Anders ... Franke, Barbara (2017). Subcortical brain volume differences in participants with attention deficit hyperactivity disorder in children and adults: a cross-sectional mega-analysis. The Lancet Psychiatry, 4 (4), 310-319. doi: 10.1016/S2215-0366(17)30049-4
2017
Journal Article
Genomic analyses identify hundreds of variants associated with age at menarche and support a role for puberty timing in cancer risk
Day, Felix R., Thompson, Deborah J., Helgason, Hannes, Chasman, Daniel I., Finucane, Hilary, Sulem, Patrick, Ruth, Katherine S., Whalen, Sean, Sarkar, Abhishek K., Albrecht, Eva, Altmaier, Elisabeth, Amini, Marzyeh, Barbieri, Caterina M., Boutin, Thibaud, Campbell, Archie, Demerath, Ellen, Giri, Ayush, He, Chunyan, Hottenga, Jouke J., Karlsson, Robert, Kolcic, Ivana, Loh, Po-Ru, Lunetta, Kathryn L., Mangino, Massimo, Marco, Brumat, McMahon, George, Medland, Sarah E., Nolte, Ilja M., Noordam, Raymond ... Perry, John R. B. (2017). Genomic analyses identify hundreds of variants associated with age at menarche and support a role for puberty timing in cancer risk. Nature Genetics, 49 (6), 834-841. doi: 10.1038/ng.3841
2017
Journal Article
Genetic effects influencing risk for major depressive disorder in China and Europe
Bigdeli, T. B., Ripke, S., Peterson, R. E., Trzaskowski, M., Bacanu, S-A, Abdellaoui, A., Andlauer, T. F. M., Beekman, A. T. F., Berger, K., Blackwood, D. H. R., Boomsma, D. I., Breen, G., Buttenschon, H. N., Byrne, E. M., Cichon, S., Clarke, T-K, Couvy-Duchesne, B., Craddock, N., de Geus, E. J. C., Degenhardt, F., Dunn, E. C., Edwards, A. C., Fanous, A. H., Forstner, A. J., Frank, J., Gill, M., Gordon, S. D., Grabe, H. J., Hamilton, S. P. ... Kendler, K. S. (2017). Genetic effects influencing risk for major depressive disorder in China and Europe. Translational Psychiatry, 7 (3) e1074, e1074-e1074. doi: 10.1038/tp.2016.292
2017
Journal Article
Identification of shared risk loci and pathways for bipolar disorder and schizophrenia
Forstner, Andreas J., Hecker, Julian, Hofmann, Andrea, Maaser, Anna, Reinbold, Céline S., Mühleisen, Thomas W., Leber, Markus, Strohmaier, Jana, Degenhardt, Franziska, Treutlein, Jens, Mattheisen, Manuel, Schumacher, Johannes, Streit, Fabian, Meier, Sandra, Herms, Stefan, Hoffmann, Per, Lacour, André, Witt, Stephanie H., Reif, Andreas, Müller-Myhsok, Bertram, Lucae, Susanne, Maier, Wolfgang, Schwarz, Markus, Vedder, Helmut, Kammerer-Ciernioch, Jutta, Pfennig, Andrea, Bauer, Michael, Hautzinger, Martin, Moebus, Susanne ... Nöthen, Markus M. (2017). Identification of shared risk loci and pathways for bipolar disorder and schizophrenia. PLoS ONE, 12 (2) e0171595, e0171595. doi: 10.1371/journal.pone.0171595
2017
Journal Article
Novel genetic loci associated with hippocampal volume
Hibar, Derrek P., Adams, Hieab H. H., Jahanshad, Neda, Chauhan, Ganesh, Stein, Jason L., Hofer, Edith, Renteria, Miguel E., Bis, Joshua C., Arias-Vasquez, Alejandro, Ikram, M. Kamran, Desrivieres, Sylvane, Vernooij, Meike W., Abramovic, Lucija, Alhusaini, Saud, Amin, Najaf, Andersson, Micael, Arfanakis, Konstantinos, Aribisala, Benjamin S., Armstrong, Nicola J., Athanasiu, Lavinia, Axelsson, Tomas, Beecham, Ashley H., Beiser, Alexa, Bernard, Manon, Blanton, Susan H., Bohlken, Marc M., Boks, Marco P., Bralten, Janita, Brickman, Adam M. ... Ikram, M. Arfan (2017). Novel genetic loci associated with hippocampal volume. Nature Communications, 8 (1) 13624, 13624. doi: 10.1038/ncomms13624
2017
Journal Article
Genetic analysis of hyperemesis gravidarum reveals association with intracellular calcium release channel (RYR2)
Fejzo, Marlena Schoenberg, Myhre, Ronny, Colodro-Conde, Lucía, MacGibbon, Kimber W, Sinsheimer, Janet S., Reddy, M. V. Prasad Linga, Pajukanta, Paivi, Nyholt, Dale R., Wright, Margaret J., Martin, Nicholas G., Engel, Stephanie M., Medland, Sarah E., Magnus, Per and Mullin, Patrick M. (2017). Genetic analysis of hyperemesis gravidarum reveals association with intracellular calcium release channel (RYR2). Molecular and Cellular Endocrinology, 439 (C), 308-316. doi: 10.1016/j.mce.2016.09.017
2017
Conference Publication
A perceptual endophenotype for mental illness: Characterising normal genetic variation in the trait
Cuéllar-Partida, Gabriel, Ngo, Trung T., Couvy-Duchesne, Baptiste, Rentería, Miguel E., Colodro Conde, Lucia, Gordon, Scott D., Hansell, Narelle K., Medland, Sarah E., Wright, Margaret J. and Martin, Nicholas G. (2017). A perceptual endophenotype for mental illness: Characterising normal genetic variation in the trait. BLiSS 2017 — Brisbane Life Science ECR Symposium, Translational Research Institute, Brisbane, 24 November 2017.
2017
Conference Publication
Genetic correlation between nausea and vomiting during pregnancy and major depressive disorder
Conde, Lucia Colodro, Paternoster, Lavinia, Lind, Penelope, Painter, Jodie, Wright, Margaret, Montgomery, Grant, Martin, Nicholas, Nyholt, Dale and Medland, Sarah (2017). Genetic correlation between nausea and vomiting during pregnancy and major depressive disorder. 47th Annual Meeting of the Behavior-Genetics-Association (BGA), Oslo, Norway, 28 June-1 July 2017. New York, NY United States: Springer New York.
2017
Conference Publication
Genetic risk for major depressive disorder as a predictor of nausea and vomiting during pregnancy
Conde, Lucia Colodro, Couvy-Duchesne, Baptiste, Lind, Penelope, Painter, Jodie, Wright, Margie, Montgomery, Grant, Nyholt, Dale and Medland, Sarah E. (2017). Genetic risk for major depressive disorder as a predictor of nausea and vomiting during pregnancy. 23rd Annual World Congress of Psychiatric Genetics (WCPG), Toronto, Canada, 16-20 October 2015. Amsterdam, Netherlands: Elsevier.
2017
Conference Publication
GWAS of complementary perceptual endophenotype measures: How do they rate?
Ngo, Trung T., Cuéllar-Partida, Gabriel, Couvy-Duchesne, Baptiste, Rentería, Miguel E., Colodro Conde, Lucia, Gordon, Scott D., Hansell, Narelle K., Medland, Sarah E., Wright, Margaret J. and Martin, Nicholas G. (2017). GWAS of complementary perceptual endophenotype measures: How do they rate?. Australasian Society for Bipolar & Depressive Disorders (ASBDD) 2017 Conference, Deakin Edge, Melbourne, 15–17 September 2017.
2017
Book Chapter
Estimating heritability from twin studies
Grasby, Katrina L., Verweij, Karin J. H., Mosing, Miriam A., Zietsch, Brendan P. and Medland, Sarah E. (2017). Estimating heritability from twin studies. In Robert C. Elston (Ed.), Statistical human genetics: methods and protocols 2nd ed. (pp. 171-194) New York, NY, United States: Humana Press. doi:10.1007/978-1-4939-7274-6_9
2017
Conference Publication
Binocular rivalry rate as a novel candidate endophenotype for bipolar disorder
Trung Ngo,, Renteria, Miguel E., Conde, Lucia Colodro, Couvy-Duchesne, Baptiste, Cuellar-Partida, Gabriel, Hansen, Narelle K., Medland, Sarah E., Miller, Steven M., Wright, Margaret J. and Martin, Nicholas G. (2017). Binocular rivalry rate as a novel candidate endophenotype for bipolar disorder. 23rd Annual World Congress of Psychiatric Genetics (WCPG), Toronto, Canada, 16-20 October 2015. Amsterdam, Netherlands: Elsevier.
Supervision
Availability
- Honorary Professor Sarah Medland is:
- Available for supervision
Before you email them, read our advice on how to contact a supervisor.
Supervision history
Current supervision
-
Doctor Philosophy
Genetic architecture of differences in symptomatology and treatment response in major depressive disorder
Principal Advisor
Other advisors: Professor Nick Martin, Associate Professor Miguel Rentería
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Doctor Philosophy
Unveiling the Complexities of Psychotic Disorders: Enhancing Treatment Safety and Understanding Heterogeneity Through Biomarkers, Genetic Analysis, and Multimodal Data Integration
Principal Advisor
Other advisors: Professor Dan Siskind
-
Doctor Philosophy
Genetic and environmental risk factors influencing mood disorders
Principal Advisor
-
Doctor Philosophy
Genetic determinants of treatment outcomes in mental health: harnessing the shared genetic etiology of mental disorders for precision psychiatry.
Principal Advisor
Completed supervision
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2022
Doctor Philosophy
Exploring the influence of genetics and heritability on the heterogeneity of ADHD presentations
Principal Advisor
Other advisors: Professor Naomi Wray
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2021
Doctor Philosophy
Motivated cognition and genetics: A psychological perspective on public understanding of behaviour genetics
Principal Advisor
Other advisors: Professor Fiona Barlow, Dr Lucia Colodro-Conde
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2019
Doctor Philosophy
Evaluation of the obesity paradox in diabetes: a longitudinal case control study
Principal Advisor
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2016
Doctor Philosophy
Forensically Relevant Applications of Genome-Wide Association Studies
Principal Advisor
Other advisors: Professor Nick Martin
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2023
Doctor Philosophy
Embracing Complexity in Psychiatric Genetics: Investigating Heterogeneity and Pleiotropy in Depression and Major Psychiatric Disorders
Associate Advisor
Other advisors: Dr Enda Byrne
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2020
Doctor Philosophy
Genetic influences on substance use behaviour, substance use disorders and psychiatric disorders
Associate Advisor
Other advisors: Professor Naomi Wray, Professor Nick Martin, Dr Lucia Colodro-Conde
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2014
Doctor Philosophy
Mapping the Genetic Architecture of Subcortical Brain Anatomy
Associate Advisor
Other advisors: Professor Nick Martin
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2012
Doctor Philosophy
The genetics of complex human behaviour: Cannabis use, personality, sexuality and mating
Associate Advisor
Other advisors: Professor Nick Martin
Media
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