
Overview
Background
Professor Ian Yang is a Thoracic Physician and Director of Thoracic Medicine at The Prince Charles Hospital, and Head of the PCH-Northside Clinical Unit, School of Clinical Medicine, Faculty of Medicine, The University of Queensland, Brisbane, Australia.
Availability
- Professor Ian Yang is:
- Available for supervision
Fields of research
Qualifications
- Bachelor (Honours) of Medicine Surgery, The University of Queensland
- Postgraduate Diploma, University of Newcastle
- Doctor of Philosophy, The University of Queensland
- Asian Pacific Society of Respirology, Asian Pacific Society of Respirology
- Royal Australasian College of Physicians, Royal Australasian College of Physicians
- The Thoracic Society of Australia and New Zealand, The Thoracic Society of Australia and New Zealand
Research interests
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Clinical and translational research in chronic lung diseases
Pathogenesis, diagnosis and treatment of chronic lung diseases, including COPD, asthma, lung cancer, mesothelioma and effects of air pollution
Research impacts
His clinical work is in the field of thoracic medicine, and his research team is studying gene-environmental interaction in COPD, asthma, lung cancer and air pollution. He is involved in the training of higher degree students in translational research into lung diseases.
He is a Chair of the National COPD Guidelines Committee of the Lung Foundation Australia, and a member of the COPD Coordinating Committee. He is Chair of the Medical Programs and Research Advisory Committee of the Asthma Foundation Queensland NSW.
Works
Search Professor Ian Yang’s works on UQ eSpace
2018
Journal Article
Molecular Characterization and Clinical Relevance of Metabolic Expression Subtypes in Human Cancers
Peng, Xinxin, Chen, Zhongyuan, Farshidfar, Farshad, Xu, Xiaoyan, Lorenzi, Philip L., Wang, Yumeng, Cheng, Feixiong, Tan, Lin, Mojumdar, Kamalika, Du, Di, Ge, Zhongqi, Li, Jun, Thomas, George V., Birsoy, Kivanc, Liu, Lingxiang, Zhang, Huiwen, Zhao, Zhongming, Marchand, Calena, Weinstein, John N., Bathe, Oliver F., Liang, Han, The Cancer Genome Atlas Research Network and Yang, Ian (2018). Molecular Characterization and Clinical Relevance of Metabolic Expression Subtypes in Human Cancers. Cell Reports, 23 (1), 255-269.e4. doi: 10.1016/j.celrep.2018.03.077
2018
Journal Article
Spatial Organization and Molecular Correlation of Tumor-Infiltrating Lymphocytes Using Deep Learning on Pathology Images
Saltz, Joel, Gupta, Rajarsi, Hou, Le, Kurc, Tahsin, Singh, Pankaj, Nguyen, Vu, Samaras, Dimitris, Shroyer, Kenneth R., Zhao, Tianhao, Batiste, Rebecca, Van Arnam, John, Shmulevich, Ilya, Rao, Arvind U. K., Lazar, Alexander J., Sharma, Ashish, Thorsson, Vesteinn, The Cancer Genome Atlas Research Network and Yang, Ian (2018). Spatial Organization and Molecular Correlation of Tumor-Infiltrating Lymphocytes Using Deep Learning on Pathology Images. Cell Reports, 23 (1), 181-193.e7. doi: 10.1016/j.celrep.2018.03.086
2018
Journal Article
Genomic and Molecular Landscape of DNA Damage Repair Deficiency across The Cancer Genome Atlas
Knijnenburg, Theo A., Wang, Linghua, Zimmermann, Michael T., Chambwe, Nyasha, Gao, Galen F., Cherniack, Andrew D., Fan, Huihui, Shen, Hui, Way, Gregory P., Greene, Casey S., Liu, Yuexin, Akbani, Rehan, Feng, Bin, Donehower, Lawrence A., Miller, Chase, Shen, Yang, Karimi, Mostafa, Chen, Haoran, Kim, Pora, Jia, Peilin, Shinbrot, Eve, Zhang, Shaojun, Liu, Jianfang, Hu, Hai, Bailey, Matthew H., Yau, Christina, Wolf, Denise, Zhao, Zhongming, Weinstein, John N. ... Yang, Ian (2018). Genomic and Molecular Landscape of DNA Damage Repair Deficiency across The Cancer Genome Atlas. Cell Reports, 23 (1), 239-254.e6. doi: 10.1016/j.celrep.2018.03.076
2018
Journal Article
Integrated Genomic Analysis of the Ubiquitin Pathway across Cancer Types
Ge, Zhongqi, Leighton, Jake S., Wang, Yumeng, Peng, Xinxin, Chen, Zhongyuan, Chen, Hu, Sun, Yutong, Yao, Fan, Li, Jun, Zhang, Huiwen, Liu, Jianfang, Shriver, Craig D., Hu, Hai, Piwnica-Worms, Helen, Ma, Li, Liang, Han, The Cancer Genome Atlas Research Network and Yang, Ian (2018). Integrated Genomic Analysis of the Ubiquitin Pathway across Cancer Types. Cell Reports, 23 (1), 213-226.e3. doi: 10.1016/j.celrep.2018.03.047
2018
Journal Article
Machine Learning Detects Pan-cancer Ras Pathway Activation in The Cancer Genome Atlas
Way, Gregory P., Sanchez-Vega, Francisco, La, Konnor, Armenia, Joshua, Chatila, Walid K., Luna, Augustin, Sander, Chris, Cherniack, Andrew D., Mina, Marco, Ciriello, Giovanni, Schultz, Nikolaus, Sanchez, Yolanda, Greene, Casey S., The Cancer Genome Atlas Research Network and Yang, Ian (2018). Machine Learning Detects Pan-cancer Ras Pathway Activation in The Cancer Genome Atlas. Cell Reports, 23 (1), 172-180.e3. doi: 10.1016/j.celrep.2018.03.046
2018
Journal Article
Pan-Cancer Analysis of lncRNA Regulation Supports Their Targeting of Cancer Genes in Each Tumor Context
Chiu, Hua-Sheng, Somvanshi, Sonal, Patel, Ektaben, Chen, Ting-Wen, Singh, Vivek P., Zorman, Barry, Patil, Sagar L., Pan, Yinghong, Chatterjee, Sujash S., Sood, Anil K., Gunaratne, Preethi H., Sumazin, Pavel, The Cancer Genome Atlas Research Network and Yang, Ian (2018). Pan-Cancer Analysis of lncRNA Regulation Supports Their Targeting of Cancer Genes in Each Tumor Context. Cell Reports, 23 (1), 297-312.e12. doi: 10.1016/j.celrep.2018.03.064
2018
Journal Article
Systematic Analysis of Splice-Site-Creating Mutations in Cancer
Jayasinghe, Reyka G., Cao, Song, Gao, Qingsong, Wendl, Michael C., Vo, Nam Sy, Reynolds, Sheila M., Zhao, Yanyan, Climente-Gonzalez, Hector, Chai, Shengjie, Wang, Fang, Varghese, Rajees, Huang, Mo, Liang, Wen-Wei, Wyczalkowski, Matthew A., Sengupta, Sohini, Li, Zhi, Payne, Samuel H., Fenyo, David, Miner, Jeffrey H., Walter, Matthew J., Vincent, Benjamin, Eyras, Eduardo, Chen, Ken, Shmulevich, Ilya, Chen, Feng, Ding, Li, The Cancer Genome Atlas Research Network and Yang, Ian (2018). Systematic Analysis of Splice-Site-Creating Mutations in Cancer. Cell Reports, 23 (1), 270-281.e3. doi: 10.1016/j.celrep.2018.03.052
2018
Journal Article
Genomic, Pathway Network, and Immunologic Features Distinguishing Squamous Carcinomas
Campbell, Joshua D., Yau, Christina, Bowlby, Reanne, Liu, Yuexin, Brennan, Kevin, Fan, Huihui, Taylor, Alison M., Wang, Chen, Walter, Vonn, Akbani, Rehan, Byers, Lauren Averett, Creighton, Chad J., Coarfa, Cristian, Shih, Juliann, Cherniack, Andrew D., Gevaert, Olivier, Prunello, Marcos, Shen, Hui, Anur, Pavana, Chen, Jianhong, Cheng, Hui, Hayes, D. Neil, Bullman, Susan, Pedamallu, Chandra Sekhar, Ojesina, Akinyemi I., Sadeghi, Sara, Mungall, Karen L., Robertson, A. Gordon, Benz, Christopher ... Yang, Ian (2018). Genomic, Pathway Network, and Immunologic Features Distinguishing Squamous Carcinomas. Cell Reports, 23 (1), 194-212.e6. doi: 10.1016/j.celrep.2018.03.063
2018
Journal Article
The Cancer Genome Atlas Comprehensive Molecular Characterization of Renal Cell Carcinoma
Ricketts, Christopher J., de Cubas, Aguirre A., Fan, Huihui, Smith, Christof C., Lang, Martin, Reznik, Ed, Bowlby, Reanne, Gibb, Ewan A., Akbani, Rehan, Beroukhim, Rameen, Bottaro, Donald P., Choueiri, Toni K., Gibbs, Richard A., Godwin, Andrew K., Haake, Scott, Hakimi, A. Ari, Henske, Elizabeth P., Hsieh, James J., Ho, Thai H., Kanchi, Rupa S., Krishnan, Bhavani, Kwaitkowski, David J., Lui, Wembin, Merino, Maria J., Mills, Gordon B., Myers, Jerome, Nickerson, Michael L., Reuter, Victor E., Schmidt, Laura S. ... Yang, Ian (2018). The Cancer Genome Atlas Comprehensive Molecular Characterization of Renal Cell Carcinoma. Cell Reports, 23 (1), 313-326.e5. doi: 10.1016/j.celrep.2018.03.075
2018
Journal Article
Scalable Open Science Approach for Mutation Calling of Tumor Exomes Using Multiple Genomic Pipelines
Ellrott, Kyle, Bailey, Matthew H., Saksena, Gordon, Covington, Kyle R., Kandoth, Cyriac, Stewart, Chip, Hess, Julian, Ma, Singer, Chiotti, Kami E., McLellan, Michael, Sofia, Heidi J., Hutter, Carolyn, Getz, Gad, Wheeler, David, Ding, Li, The Cancer Genome Atlas Research Network and Yang, Ian (2018). Scalable Open Science Approach for Mutation Calling of Tumor Exomes Using Multiple Genomic Pipelines. Cell Systems, 6 (3), 271-281.e7. doi: 10.1016/j.cels.2018.03.002
2018
Journal Article
Pan-cancer Alterations of the MYC Oncogene and Its Proximal Network across the Cancer Genome Atlas
Schaub, Franz X., Dhankani, Varsha, Berger, Ashton C., Trivedi, Mihir, Richardson, Anne B., Shaw, Reid, Zhao, Wei, Zhang, Xiaoyang, Ventura, Andrea, Liu, Yuexin, Ayer, Donald E., Hurlin, Peter J., Cherniack, Andrew D., Eisenman, Robert N., Bernard, Brady, Grandori, Carla, The Cancer Genome Atlas Network and Yang, Ian (2018). Pan-cancer Alterations of the MYC Oncogene and Its Proximal Network across the Cancer Genome Atlas. Cell Systems, 6 (3), 282-300.e2. doi: 10.1016/j.cels.2018.03.003
2018
Journal Article
Editorial on PanCan study
Marshall, Henry M., Yang, Ian A., Bowman, Rayleen V. and Fong, Kwun M. (2018). Editorial on PanCan study. Translational Lung Cancer Research, 7 (Suppl 1), S57-S59. doi: 10.21037/tlcr.2018.01.17
2018
Conference Publication
Management of acute COPD exacerbations: Do we follow the guidelines?
Cousins, J., Wood-Baker, R., Wark, P., Yang, I., Hutchinson, A., Sajkov, D., Gibson, P. and Mcdonald, V. (2018). Management of acute COPD exacerbations: Do we follow the guidelines?. The Australia & New Zealand Society of Respiratory Science and The Thoracic Society of Australia and New Zealand (ANZSRS/TSANZ) Annual Scientific Meeting, Adelaide, Australia, 23–27 March 2018. Hoboken, NJ United States: Wiley.
2018
Journal Article
The contribution of respiratory microbiome analysis to a treatable traits model of care
Taylor, Steven L., O'Farrell, Hannah E., Simpson, Jodie L., Yang, Ian A. and Rogers, Geraint B. (2018). The contribution of respiratory microbiome analysis to a treatable traits model of care. Respirology, 24 (1), 19-28. doi: 10.1111/resp.13411
2018
Conference Publication
Primary human bronchial epithelial cell responses to diesel and novel biodiesel emissions
Vaughan, Annalicia, Stevanovic, Svetlana, Jafari, Mohammad, Bowman, Rayleen, Fong, Kwun, Ristovski, Zoran and Yang, Ian (2018). Primary human bronchial epithelial cell responses to diesel and novel biodiesel emissions. 28th International Congress of the European Respiratory Society (ERS), Paris, France, 15-19 September 2018. Lausanne, Switzerland: European Respiratory Society. doi: 10.1183/13993003.congress-2018.PA4243
2018
Conference Publication
Association between bacterial load and inflammatory gene expression in COPD exacerbations
O'Farrell, Hannah, Shaw, Janet, Bowman, Rayleen, Fong, Kwun and Yang, Ian (2018). Association between bacterial load and inflammatory gene expression in COPD exacerbations. 28th International Congress of the European-Respiratory-Society (ERS), Paris, France, 15-19 September 2018. Lausanne, Switzerland: European Respiratory Society. doi: 10.1183/13993003.congress-2018.PA3864
2018
Conference Publication
Sputum biospecimen quality and suitability for microbiome characterisation in COPD
Shaw, Janet, O'Farrell, Hannah, Ferry, Olivia, Fung, Pamela, Courtney, Deborah, Bowman, Rayleen, Fong, Kwun and Yang, Ian (2018). Sputum biospecimen quality and suitability for microbiome characterisation in COPD. 28th International Congress of the European-Respiratory-Society (ERS), Paris, France, 15-19 September 2018. Lausanne, Switzerland: European Respiratory Society. doi: 10.1183/13993003.congress-2018.PA5304
2017
Journal Article
COPD-X australian and New Zealand guidelines for the diagnosis and management of chronic obstructive pulmonary disease: 2017 update
Yang, Ian A., Brown, Juliet L., George, Johnson, Jenkins, Sue, McDonald, Christine F., McDonald, Vanessa M., Phillips, Kirsten, Smith, Brian J., Zwar, Nicholas A. and Dabscheck, Eli (2017). COPD-X australian and New Zealand guidelines for the diagnosis and management of chronic obstructive pulmonary disease: 2017 update. Medical Journal of Australia, 207 (10), 436-442. doi: 10.5694/mja17.00686
2017
Journal Article
The effect of different radiological models on diagnostic accuracy and lung cancer screening performance
Marshall, Henry M., Zhao, Henry, Bowman, Rayleen V., Passmore, Linda H., McCaul, Elizabeth M., Yang, Ian A. and Fong, Kwun M. (2017). The effect of different radiological models on diagnostic accuracy and lung cancer screening performance. Thorax, 72 (12), 1147-1150. doi: 10.1136/thoraxjnl-2016-209624
2017
Journal Article
Ultrafine particle transport and deposition in a large scale 17-generation lung model
Islam, Mohammad S., Saha, Suvash C., Sauret, Emilie, Gemci, Tevfik, Yang, Ian A. and Gu, Y. T. (2017). Ultrafine particle transport and deposition in a large scale 17-generation lung model. Journal of Biomechanics, 64, 16-25. doi: 10.1016/j.jbiomech.2017.08.028
Funding
Current funding
Past funding
Supervision
Availability
- Professor Ian Yang is:
- Available for supervision
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Available projects
-
Diagnosis and treatment of chronic obstructive pulmonary disease
Improving approaches to the early diagnosis, monitoring and management of patients with COPD
-
Lung ageing
Genetics and epigenetics of ageing in the lung
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The lung's response to air pollution
Gene-environment interaction in the lung's response to exposure to air pollutants
Supervision history
Current supervision
-
Master Philosophy
Elastin turnover in the lung microenvironment and its significance in Lung Repair and Non-Small Cell Lung Carcinoma (NSCLC)
Principal Advisor
-
-
Master Philosophy
Elastin turnover in the lung microenvironment and its significance in Lung Repair and Non-Small Cell Lung Carcinoma (NSCLC)
Principal Advisor
Other advisors: Professor Kwun Fong
-
Doctor Philosophy
Molecular drivers of lung cancer.
Associate Advisor
-
Doctor Philosophy
Randomised pragmatic trial of comprehensive tissue sampling enabled by ultrathin bronchoscopic Radial probe EndoBronchial Ultrasound versus CT-guided TransThoracic needle aspiration/biopsy (REBUTT) for evaluation of peripheral pulmonary lesions.
Associate Advisor
Other advisors: Professor Kwun Fong
-
Master Philosophy
A multivariable prediction model for osteoporotic fracture and low bone density in a lung cancer screening cohort
Associate Advisor
Other advisors: Professor Kwun Fong, Associate Professor Henry Marshall
-
Doctor Philosophy
Precision medicine in the genomic era: emerging technologies for molecular profiling of lung cancer
Associate Advisor
Other advisors: Professor Kwun Fong
-
Doctor Philosophy
Blood biomarkers for lung cancer screening
Associate Advisor
Other advisors: Professor Kwun Fong, Associate Professor Henry Marshall
-
Master Philosophy
A multivariable prediction model for osteoporotic fracture in a lung cancer screening cohort
Associate Advisor
Other advisors: Professor Kwun Fong, Associate Professor Henry Marshall
Completed supervision
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2021
Master Philosophy
The Clinical Journey of Patients with a Severe Exacerbation of Chronic Obstructive Pulmonary Disease (COPD): from the Ambulance to the Emergency Department to the Hospital Ward
Principal Advisor
Other advisors: Professor Kwun Fong
-
2021
Doctor Philosophy
Diagnostic, prognostic and therapeutic applications of extracellular vesicles in chronic obstructive pulmonary disease and lung cancer
Principal Advisor
Other advisors: Professor Kwun Fong
-
2019
Master Philosophy
Cognitive behavioural therapy (CBT) for patients with chronic lung disease and psychological comorbidities undergoing pulmonary rehabilitation
Principal Advisor
Other advisors: Professor Kwun Fong
-
2018
Doctor Philosophy
The response of human bronchial epithelial cells to outdoor air pollution: Interventions to protect the diseased lung against diesel emission exposure
Principal Advisor
Other advisors: Professor Kwun Fong
-
2012
Master Philosophy
Genetic influences on right ventricular systolic pressure (RVSP) in chronic obstructive pulmonary disease (COPD)
Principal Advisor
Other advisors: Professor Kwun Fong, Associate Professor Paul Zimmerman
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2024
Doctor Philosophy
Population-wide outcomes of catheter ablation of atrial fibrillation
Associate Advisor
Other advisors: Associate Professor Isuru Ranasinghe
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2023
Doctor Philosophy
Air pollution and child health in low- and middle-income countries
Associate Advisor
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2014
Doctor Philosophy
MOLECULAR MECHANISMS UNDERLYING PROGRESSION OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE (COPD)
Joint Principal Advisor
Other advisors: Professor Kwun Fong
-
2024
Doctor Philosophy
Screening For Biomarkers in Non-Small Cell Lung Cancer
Associate Advisor
Other advisors: Professor Kwun Fong
-
2023
Doctor Philosophy
Using proteomics to understand and prevent asthma exacerbations with macrolide antibiotics
Associate Advisor
Other advisors: Honorary Professor John Upham
-
2022
Doctor Philosophy
The Association Between Maternal and Childhood Environmental Exposures and Mental Health and Cognitive Function of Australian Children.
Associate Advisor
Other advisors: Professor Gita Mishra
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2022
Doctor Philosophy
Evaluation of Pleural Fluid Extracellular Vesicles for Diagnostic Utility in Malignant Pleural Mesothelioma
Associate Advisor
Other advisors: Professor Kwun Fong
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2021
Doctor Philosophy
Evaluating NanoString Technology to Enhance the Molecular Characterisation of Lung Cancer
Associate Advisor
Other advisors: Professor Kwun Fong
-
2021
Doctor Philosophy
Retrospective cohort studies on the lung cancer secondary care diagnostic pathway: Factors that influence waiting time intervals and patient experience
Associate Advisor
Other advisors: Professor Kwun Fong
-
2017
Doctor Philosophy
The Role of Exhaled Breath Analysis in the Diagnosis and Monitoring of Lung Diseases
Associate Advisor
Other advisors: Associate Professor David Fielding, Professor Kwun Fong, Associate Professor Paul Zimmerman
-
2015
Master Philosophy
Lung cancer in rural and remote Aboriginal and Torres Strait Islander communities in Queensland: Awareness and identifying health needs in a cultural context.
Associate Advisor
Other advisors: Professor Kwun Fong
-
2015
Doctor Philosophy
The Queensland Lung Cancer Screening Study
Associate Advisor
Other advisors: Professor Kwun Fong, Associate Professor Paul Zimmerman
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2014
Doctor Philosophy
Genomic characterisation of asbestos-related lung cancer
Associate Advisor
Other advisors: Professor Kwun Fong
-
2013
Doctor Philosophy
Aberrant microRNA Expression in Lung Cancer
Associate Advisor
Other advisors: Professor Kwun Fong
-
2013
Doctor Philosophy
MOLECULAR BIOMARKERS IN THORACIC ONCOLOGY
Associate Advisor
Other advisors: Professor Kwun Fong
-
2008
Master Philosophy
The Genetic Basis of Carvedilol Responsiveness in Human Heart Failure
Associate Advisor
Other advisors: Honorary Professor Peter Molenaar
Media
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