
Overview
Background
Professor Geoffrey McLachlan's research interests are in: data mining, statistical analysis of microarray, gene expression data, finite mixture models and medical statistics.
Professor McLachlan received his PhD from the University of Queensland in 1974 and his DSc from there in 1994. His current research projects in statistics are in the related fields of classification, cluster and discriminant analyses, image analysis, machine learning, neural networks, and pattern recognition, and in the field of statistical inference. The focus in the latter field has been on the theory and applications of finite mixture models and on estimation via the EM algorithm.
A common theme of his research in these fields has been statistical computation, with particular attention being given to the computational aspects of the statistical methodology. This computational theme extends to Professor McLachlan's more recent interests in the field of data mining.
He is also actively involved in research in the field of medical statistics and, more recently, in the statistical analysis of microarray gene expression data.
Availability
- Professor Geoffrey McLachlan is:
- Available for supervision
- Media expert
Fields of research
Qualifications
- Bachelor (Honours) of Science (Advanced), The University of Queensland
- Doctor of Philosophy, The University of Queensland
- Doctoral Diploma of Science (Advanced), The University of Queensland
- Australian Mathematical Society, Australian Mathematical Society
Works
Search Professor Geoffrey McLachlan’s works on UQ eSpace
1997
Book
The EM algorithm and extensions
McLachlan, Geoffrey J. and Krishnan, Thriyambakam (1997). The EM algorithm and extensions. New York, United States: Wiley.
1996
Journal Article
Maximum likelihood clustering via normal mixture models
McLachlan, GJ, Peel, D and Whiten, WJ (1996). Maximum likelihood clustering via normal mixture models. Signal Processing-Image Communication, 8 (2), 105-111. doi: 10.1016/0923-5965(95)00039-9
1996
Conference Publication
Clustering of magnetic resonance images
McLachlan, GJ, Ng, SK, Galloway, GJ and Wang, D (1996). Clustering of magnetic resonance images. Symposium of the Statistical-Computing-Section, at the Annual Meeting of the American-Statistical-Association, Chicago Il, Aug 04-08, 1996. ALEXANDRIA: AMER STATISTICAL ASSOC.
1996
Journal Article
Likelihood-based approaches to pattern recognition
McLachlan, G. J. (1996). Likelihood-based approaches to pattern recognition. Far East Journal of Mathematical Sciences, 4 (Pt. 1), 1-29.
1995
Conference Publication
The distribution of transferrin saturation in an asymptomatic Australian population: relevance to the early diagnosis of hemochromatosis Washington, from. December 1-5, 1995.
McLaren, C.E., McLachlan, G.J., Webb, S.J., Jazwinska, E.C., Crawford, D.H.G., Gordeuk, V.R., McLaren, G.D. and Powell, LW (1995). The distribution of transferrin saturation in an asymptomatic Australian population: relevance to the early diagnosis of hemochromatosis Washington, from. December 1-5, 1995.. 37th Annual Meeting of the American Society of Hematology, Seattle, WA, United States, 1-5 December 1995. Washington, DC, United States: American Society of Hematology.
1995
Journal Article
An Algorithm for the Likelihood Ratio Test of One Versus 2 Components in a Normal Mixture Model Fitted to Grouped and Truncated Data
McLachlan, GJ, McLaren, CE and Matthews, D (1995). An Algorithm for the Likelihood Ratio Test of One Versus 2 Components in a Normal Mixture Model Fitted to Grouped and Truncated Data. Communications in Statistics-Simulation and Computation, 24 (4), 965-985. doi: 10.1080/03610919508813288
1995
Journal Article
Asymptotic Relative Efficiency of the Linear Discriminant Function Under Partial Nonrandom Classification of the Training Data
McLachlan, GJ and Scot, D (1995). Asymptotic Relative Efficiency of the Linear Discriminant Function Under Partial Nonrandom Classification of the Training Data. Journal of Statistical Computation and Simulation, 52 (4), 415-426. doi: 10.1080/00949659508811689
1994
Conference Publication
Early Detection of the Development of Iron-Deficiency by Patient-Specific Sequential-Analysis of Hematological Tests
McLaren, CE, McLaren, GD, Kambour, EL, McLachlan, GJ, Lukaski, HC, Li, X and Brittenham, GM (1994). Early Detection of the Development of Iron-Deficiency by Patient-Specific Sequential-Analysis of Hematological Tests. PHILADELPHIA: SLACK INC.
1994
Conference Publication
Early Detection of the Development of Iron-Deficiency by Patient-Specific Sequential-Analysis of Hematological Tests
McLaren, GD, McLaren, CE, Kambour, EL, Lukaski, HC, Xia, L, McLachlan, GJ and Brittenham, GM (1994). Early Detection of the Development of Iron-Deficiency by Patient-Specific Sequential-Analysis of Hematological Tests. THOROFARE: W B SAUNDERS CO.
1994
Journal Article
Relationship of Platelet-Aggregation to Bleeding After Cardiopulmonary Bypass
Ray, MJ, Hawson, Gat, Just, Sje, McLachlan, G and Obrien, M (1994). Relationship of Platelet-Aggregation to Bleeding After Cardiopulmonary Bypass. Annals of Thoracic Surgery, 57 (4), 981-986.
1994
Journal Article
Parametric-Estimation in a Genetic Mixture Model with Application to Nuclear Family Data
Shoukri, MM and McLachlan, GJ (1994). Parametric-Estimation in a Genetic Mixture Model with Application to Nuclear Family Data. Biometrics, 50 (1), 128-139. doi: 10.2307/2533203
1994
Journal Article
Relationship of platelet aggregation to bleeding after cardiopulmonary bypass
Ray, Michael J., Hawson, Geoffrey A.T., Just, Sarah J.E., McLachlan, Geoffery and O'Brien, Mark (1994). Relationship of platelet aggregation to bleeding after cardiopulmonary bypass. The Annals of Thoracic Surgery, 57 (4), 981-986. doi: 10.1016/0003-4975(94)90218-6
1994
Journal Article
On the role of finite mixture models in survival analysis.
McLachlan G.J. and McGiffin D.C. (1994). On the role of finite mixture models in survival analysis.. Statistical methods in medical research, 3 (3), 211-226. doi: 10.1177/096228029400300302
1994
Journal Article
Estimation of Mixing Proportions in the Presence of Autoregressively Correlated Training Data - the Case of 2 Univariate Normal-Populations
Lawoko, Cro and McLachlan, GJ (1994). Estimation of Mixing Proportions in the Presence of Autoregressively Correlated Training Data - the Case of 2 Univariate Normal-Populations. Communications in Statistics-Simulation and Computation, 23 (3), 591-613. doi: 10.1080/03610919408813189
1994
Journal Article
Neural Networks and Related Methods for Classification - Discussion
Whittle, P, Kay, J, Hand, DJ, Tarassenko, L, Brown, PJ, Titterington, DM, Taylor, C, Gilks, WR, Critchley, F, Mayne, AJ, Wahba, G, Luttrell, SP, Baczkowski, AJ, Mardia, KV, Breiman, L, Buntine, W, Chatfield, C, Deveaux, RD, Darken, CJ, Ungar, LH, Glendinning, RH, Hastie, T, Tibshirani, R, McLachlan, GJ, Michie, D, Owen, AB, Wolpert, DH and Ripley, BD (1994). Neural Networks and Related Methods for Classification - Discussion. Journal of the Royal Statistical Society Series B-Methodological, 56 (3), 437-456.
1993
Journal Article
An Analysis of Risk-Factors for Death and Mode-Specific Death After Aortic-Valve Replacement with Allograft, Xenograft, and Mechanical Valves
McGiffin, DC, Obrien, MF, Galbraith, AJ, McLachlan, GJ, Stafford, EG, Gardner, Mah, Pohlner, PG, Early, L and Kear, L (1993). An Analysis of Risk-Factors for Death and Mode-Specific Death After Aortic-Valve Replacement with Allograft, Xenograft, and Mechanical Valves. Journal of Thoracic and Cardiovascular Surgery, 106 (5), 895-911. doi: 10.1016/s0022-5223(19)34046-2
1993
Journal Article
A Connection Between the Logit Model, Normal Discriminant-Analysis, and Multivariate Normal Mixtures - Comment
McLachlan, G (1993). A Connection Between the Logit Model, Normal Discriminant-Analysis, and Multivariate Normal Mixtures - Comment. American Statistician, 47 (1), 88-88.
1992
Journal Article
Aortic-Valve Infection - Risk-Factors for Death and Recurrent Endocarditis After Aortic-Valve Replacement
McGiffin, DC, Galbraith, AJ, McLachlan, GJ, Stower, RE, Wong, ML, Stafford, EG, Gardner, Mah, Pohlner, PG and Obrien, MF (1992). Aortic-Valve Infection - Risk-Factors for Death and Recurrent Endocarditis After Aortic-Valve Replacement. Journal of Thoracic and Cardiovascular Surgery, 104 (2), 511-520. doi: 10.1016/s0022-5223(19)34813-5
1992
Journal Article
Fitting finite mixture models in a regression context
Jones, P. N. and McLachlan, G. J. (1992). Fitting finite mixture models in a regression context. Australian Journal of Statistics, 34 (2), 233-240. doi: 10.1111/j.1467-842X.1992.tb01356.x
1992
Journal Article
Improving the convergence rate of the EM algorithm for a mixture model fitted to grouped truncated data
Jones, Peter N. and McLachlan, Geoffrey J. (1992). Improving the convergence rate of the EM algorithm for a mixture model fitted to grouped truncated data. Journal of Statistical Computation and Simulation, 43 (1-2), 31-44. doi: 10.1080/00949659208811426
Funding
Current funding
Past funding
Supervision
Availability
- Professor Geoffrey McLachlan is:
- Available for supervision
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Supervision history
Current supervision
-
Doctor Philosophy
Role of Finite Mixture Models in Semi-Supervised Learning
Principal Advisor
Other advisors: Dr Sharon Lee
-
Doctor Philosophy
Using statistical genetics approaches to gain insight into patterns of variation in complex traits
Associate Advisor
Other advisors: Dr Vivi Arief, Dr Quan Nguyen, Emeritus Professor Kaye Basford
-
Doctor Philosophy
The Application of Advanced Statistical Methods to Hyperspectral Images in Mineral Exploration
Associate Advisor
Other advisors: Dr Dion Weatherley, Professor Rick Valenta
-
Doctor Philosophy
Learning a mineralised fault network at the Cracow Gold Mine from geologically-informed 3D synthetic seismic data
Associate Advisor
Other advisors: Dr Dion Weatherley, Professor Rick Valenta
-
Doctor Philosophy
Using statistical genetics approaches to gain insight into patterns of variation in complex traits
Associate Advisor
Other advisors: Dr Vivi Arief, Dr Quan Nguyen, Emeritus Professor Kaye Basford
Completed supervision
-
2024
Doctor Philosophy
Detecting the unexpected in astronomical data using complexity based approaches
Principal Advisor
-
2023
Doctor Philosophy
Improving Predictability of Minerals Processing Models by Developing a Methodology based-on Machine Learning Techniques
Principal Advisor
-
-
2015
Doctor Philosophy
Finite Mixture Models for Regression Problems
Principal Advisor
Other advisors: Dr Ian Wood
-
2014
Doctor Philosophy
Finite Mixture Modelling using Multivariate Skew Distributions
Principal Advisor
Other advisors: Dr Ian Wood
-
2012
Doctor Philosophy
Detection of Differentially Expressed Genes via Mixture Models and Cluster Analysis
Principal Advisor
Other advisors: Dr Ian Wood
-
2009
Doctor Philosophy
Statistical analysis of high-dimensional gene expression data
Principal Advisor
-
2005
Doctor Philosophy
CLUSTERING WITH MIXED VARIABLES
Principal Advisor
-
2004
Master Science
Modelling the statistical behaviour of temperature using a modified Brennan and Schwartz 1982 interest rate model
Principal Advisor
Other advisors: Associate Professor Michael Bulmer
-
2024
Doctor Philosophy
The Wealth of Features: towards a coherent cooperative game theory for feature importance
Associate Advisor
Other advisors: Associate Professor Sally Shrapnel, Dr Ian Wood
-
2019
Doctor Philosophy
Maximum pseudolikelihood estimation with Markov random fields in the segmentation of brain magnetic resonance images
Associate Advisor
Other advisors: Dr Ian Wood
-
-
2016
Doctor Philosophy
Estimation of missing values in multivariate multi-environment trial data for three-way pattern analysis
Associate Advisor
Other advisors: Emeritus Professor Kaye Basford
-
-
Doctor Philosophy
TOPOLOGICAL MODELS OF TRANSMEMBRANE PROTEINS FOR SUBCELLULAR LOCALIZATION PREDICTION
Associate Advisor
Other advisors: Associate Professor Marcus Gallagher, Professor Mikael Boden
Media
Enquiries
Contact Professor Geoffrey McLachlan directly for media enquiries about:
- Bioinformatics
- Computation - statistics
- Computer learning
- Data mining
- Gene expression data
- Image analysis - statistics
- Machine learning
- Neural networks
- Pattern recognition - statistics
- Statistical methodology
- Statistics
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