Professor

Bradley Launikonis

Email: 
Phone: 
+61 7 336 54301

Availability

Professor Bradley Launikonis is:
Available for supervision

Fields of research

Biological Sciences Zoology

Qualifications

  • Doctor of Philosophy, La Trobe University

Search Professor Bradley Launikonis’s works on UQ eSpace

95 works between 1997 and 2025
All (95) Journal Article (71) Book Chapter (1) Conference Publication (23)

41 - 60 of 95 works

2016

Journal Article

Leaky ryanodine receptors delay the activation of store overload-induced Ca2+ release, a mechanism underlying malignant hyperthermia-like events in dystrophic muscle

Cully, Tanya R. and Launikonis, Bradley S. (2016). Leaky ryanodine receptors delay the activation of store overload-induced Ca2+ release, a mechanism underlying malignant hyperthermia-like events in dystrophic muscle. American Journal of Physiology: Cell Physiology, 310 (8), C673-C680. doi: 10.1152/ajpcell.00366.2015

Leaky ryanodine receptors delay the activation of store overload-induced Ca2+ release, a mechanism underlying malignant hyperthermia-like events in dystrophic muscle

2016

Conference Publication

The T-System Provides a Dynamic Ca2+-Buffer in Human Skeletal Muscle Fibres

Cully, Tanya R. and Launikonis, Bradley S. (2016). The T-System Provides a Dynamic Ca2+-Buffer in Human Skeletal Muscle Fibres. 60th Annual Meeting of the Biophysical-Society, Los Angeles, CA, United States, Feb 27-Mar 02, 2016. Cambridge, MA United States: Cell Press. doi: 10.1016/j.bpj.2015.11.3193

The T-System Provides a Dynamic Ca2+-Buffer in Human Skeletal Muscle Fibres

2016

Journal Article

Additional in-series compliance reduces muscle force summation and alters the time course of force relaxation during fixed-end contractions

Mayfield, Dean L., Launikonis, Bradley S., Cresswell, Andrew G. and Lichtwark, Glen A. (2016). Additional in-series compliance reduces muscle force summation and alters the time course of force relaxation during fixed-end contractions. Journal of Experimental Biology, 219 (22), 3587-3596. doi: 10.1242/jeb.143123

Additional in-series compliance reduces muscle force summation and alters the time course of force relaxation during fixed-end contractions

2016

Conference Publication

Ryanodine Receptor Activity Regulates the Levels of Ca2+ Extrusion and Store-Operated Ca2+ Entry in Skeletal Muscle

Cully, Tanya R., Choi, Rocky H., Shannon, Thomas R. and Launikonis, Bradley S. (2016). Ryanodine Receptor Activity Regulates the Levels of Ca2+ Extrusion and Store-Operated Ca2+ Entry in Skeletal Muscle. 60th Annual Meeting of the Biophysical-Society, Los Angeles, CA, United States, Feb 27-Mar 02, 2016. Cambridge, MA United States: Cell Press. doi: 10.1016/j.bpj.2015.11.1019

Ryanodine Receptor Activity Regulates the Levels of Ca2+ Extrusion and Store-Operated Ca2+ Entry in Skeletal Muscle

2015

Conference Publication

Determination of the Junctional Space [Ca2+] Set by Ryanodine Receptor Leak in Slow- and Fast-Twitch Muscle Fibres

Cully, Tanya R. and Launikonis, Bradley S. (2015). Determination of the Junctional Space [Ca2+] Set by Ryanodine Receptor Leak in Slow- and Fast-Twitch Muscle Fibres. Biophysical Society 59th Annual Meeting, Baltimore, MD United States, 7-11 February 2015. Cambridge, MA United States: Cell Press. doi: 10.1016/j.bpj.2014.11.1483

Determination of the Junctional Space [Ca2+] Set by Ryanodine Receptor Leak in Slow- and Fast-Twitch Muscle Fibres

2014

Journal Article

Activation and propagation of Ca2+ release from inside the sarcoplasmic reticulum network of mammalian skeletal muscle

Cully, Tanya R., Edwards, Joshua N. and Launikonis, Bradley S. (2014). Activation and propagation of Ca2+ release from inside the sarcoplasmic reticulum network of mammalian skeletal muscle. Journal of Physiology, 592 (17), 3727-3746. doi: 10.1113/jphysiol.2014.274274

Activation and propagation of Ca2+ release from inside the sarcoplasmic reticulum network of mammalian skeletal muscle

2014

Journal Article

Observation of the molecular organization of calcium release sites in fast- and slowtwitch skeletal muscle with nanoscale imaging

Jayasinghe, Isuru D., Munro, Michelle, Baddeley, David, Launikonis, Bradley S. and Soeller, Christian (2014). Observation of the molecular organization of calcium release sites in fast- and slowtwitch skeletal muscle with nanoscale imaging. Journal of the Royal Society Interface, 11 (99) 0570, 20140570. doi: 10.1098/rsif.2014.0570

Observation of the molecular organization of calcium release sites in fast- and slowtwitch skeletal muscle with nanoscale imaging

2014

Journal Article

Evidence that collaboration between HIF-1alpha and Notch-1 promotes neuronal cell death in ischemic stroke

Cheng, Yi-Lin, Park, Jong-Sung, Manzanero, Silvia, Choi, Yuri, Baik, Sang-Ha, Okun, Eitan, Gelderblom, Mathias, Fann, David Yang-Wei, Magnus, Tim, Launikonis, Bradley S., Mattson, Mark P., Sobey, Christopher G., Jo, Dong-Gyu and Arumugam, Thiruma V. (2014). Evidence that collaboration between HIF-1alpha and Notch-1 promotes neuronal cell death in ischemic stroke. Neurobiology of Disease, 62, 286-295. doi: 10.1016/j.nbd.2013.10.009

Evidence that collaboration between HIF-1alpha and Notch-1 promotes neuronal cell death in ischemic stroke

2014

Conference Publication

Proton Fluxes Across the Tubular (T-) System Membrane of Rat Fast-Twitch Fibres

Launikonis, Bradley S., Cully, Tanya R., Csernoch, Laszlo and Stephenson, D. George (2014). Proton Fluxes Across the Tubular (T-) System Membrane of Rat Fast-Twitch Fibres. 58th Annual Meeting of the Biophysical-Society, San Francisco Ca, Feb 15-19, 2014. CAMBRIDGE: CELL PRESS. doi: 10.1016/j.bpj.2013.11.752

Proton Fluxes Across the Tubular (T-) System Membrane of Rat Fast-Twitch Fibres

2014

Conference Publication

Resolving the Calcium Release Machinery of Mammalian Fast- and Slow-Twitch Skeletal Muscle

Jayasinghe, Isuru D., Munro, Michelle, Baddeley, David, Launikonis, Bradley S. and Soeller, Christian (2014). Resolving the Calcium Release Machinery of Mammalian Fast- and Slow-Twitch Skeletal Muscle. 58th Annual Meeting of the Biophysical-Society, San Francisco, CA, United States, Feb 15-19, 2014. Cambridge, MA United States: Cell Press. doi: 10.1016/j.bpj.2013.11.736

Resolving the Calcium Release Machinery of Mammalian Fast- and Slow-Twitch Skeletal Muscle

2014

Conference Publication

A Chloride Channel Blocker Prevents Inorganic Phosphate Accumulation and Its Effects in the Sarcoplasmic Reticulum of Frog Permeabilized Skeletal Muscle Fibers

Jose Ferreira, Juan, Pequera, German, Launikonis, Bradley, Rios, Eduardo and Brum, Gustavo (2014). A Chloride Channel Blocker Prevents Inorganic Phosphate Accumulation and Its Effects in the Sarcoplasmic Reticulum of Frog Permeabilized Skeletal Muscle Fibers. 58th Annual Meeting of the Biophysical-Society, San Francisco, CA, United States, Feb 15-19, 2014. Cambridge, MA United States: Cell Press. doi: 10.1016/j.bpj.2013.11.2975

A Chloride Channel Blocker Prevents Inorganic Phosphate Accumulation and Its Effects in the Sarcoplasmic Reticulum of Frog Permeabilized Skeletal Muscle Fibers

2014

Conference Publication

Ca2+ Uptake by the Tubular (T-) System Membrane of Rat Fast-Twitch Fibres

Cully, Tanya R., Edwards, Joshua N., Shannon, Thomas R. and Launikonis, Bradley (2014). Ca2+ Uptake by the Tubular (T-) System Membrane of Rat Fast-Twitch Fibres. 58th Annual Meeting of the Biophysical-Society, San Francisco, CA, United States, Feb 15-19, 2014. Cambridge, MA United States: Cell Press. doi: 10.1016/j.bpj.2013.11.749

Ca2+ Uptake by the Tubular (T-) System Membrane of Rat Fast-Twitch Fibres

2013

Journal Article

Three-dimensional reconstruction and analysis of the tubular system of vertebrate skeletal muscle

Jayasinghe, Isuru D. and Launikonis, Bradley S. (2013). Three-dimensional reconstruction and analysis of the tubular system of vertebrate skeletal muscle. Journal of Cell Science, 126 (17), 4048-4058. doi: 10.1242/jcs.131565

Three-dimensional reconstruction and analysis of the tubular system of vertebrate skeletal muscle

2013

Journal Article

Examination of the subsarcolemmal tubular system of mammalian skeletal muscle fibers

Jayasinghe, Isuru D., Lo, Harriet P., Morgan, Garry P., Baddeley, David, Parton, Robert G., Soeller, Christian and Launikonis, Bradley S. (2013). Examination of the subsarcolemmal tubular system of mammalian skeletal muscle fibers. Biophysical Journal, 104 (11), L19-L21. doi: 10.1016/j.bpj.2013.04.029

Examination of the subsarcolemmal tubular system of mammalian skeletal muscle fibers

2013

Journal Article

Store-operated Ca2+ entry is not required for store refilling in skeletal muscle

Cully, Tanya R. and Launikonis, Bradley S. (2013). Store-operated Ca2+ entry is not required for store refilling in skeletal muscle. Clinical and Experimental Pharmacology and Physiology, 40 (5), 338-344. doi: 10.1111/1440-1681.12078

Store-operated Ca2+ entry is not required for store refilling in skeletal muscle

2013

Journal Article

Evidence that the EphA2 receptor exacerbates ischemic brain injury

Thundyil, John, Manzanero, Silvia, Pavlovski, Dale, Cully, Tanya R., Lok, Ker-Zhing, Widiapradja, Alexander, Chunduri, Prasad, Jo, Dong-Gyu, Naruse, Chie, Asano, Masahide, Launikonis, Bradley S., Sobey, Christopher G., Coulthard, Mark G. and Arumugam, Thiruma V. (2013). Evidence that the EphA2 receptor exacerbates ischemic brain injury. PLoS One, 8 (1) e53528, e53528.1-e53528.8. doi: 10.1371/journal.pone.0053528

Evidence that the EphA2 receptor exacerbates ischemic brain injury

2013

Conference Publication

Store-Operated Ca2+ Entry is a Tonic and Phasic Signal in Skeletal Muscle

Cully, Tanya R. and Launikonis, Bradley S. (2013). Store-Operated Ca2+ Entry is a Tonic and Phasic Signal in Skeletal Muscle. 57th Annual Meeting of the Biophysical Society, Philadelphia Pa, 02-06 February 2013. Maryland Heights, MO United States: Cell Press. doi: 10.1016/j.bpj.2012.11.3364

Store-Operated Ca2+ Entry is a Tonic and Phasic Signal in Skeletal Muscle

2012

Journal Article

Growth hormone secretagogues preserve the electrophysiological properties of mouse cardiomyocytes isolated from in Vitro ischemia/reperfusion heart

Ma, Yi, Zhang, Lin, Launikonis, Bradley S. and Chen, Chen (2012). Growth hormone secretagogues preserve the electrophysiological properties of mouse cardiomyocytes isolated from in Vitro ischemia/reperfusion heart. Endocrinology, 153 (11), 5480-5490. doi: 10.1210/en.2012-1404

Growth hormone secretagogues preserve the electrophysiological properties of mouse cardiomyocytes isolated from in Vitro ischemia/reperfusion heart

2012

Journal Article

Changes in plasma membrane Ca-ATPase and stromal interacting molecule 1 expression levels for Ca2+ signaling in dystrophic mdx mouse muscle.

Cully, Tanya R., Edwards, Joshua N., Friedrich, Oliver, Stephenson, D. George, Murphy, Robyn M. and Launikonis, Bradley S. (2012). Changes in plasma membrane Ca-ATPase and stromal interacting molecule 1 expression levels for Ca2+ signaling in dystrophic mdx mouse muscle.. American Journal of Physiology - Cell Physiology, 303 (5), C567-C576. doi: 10.1152/ajpcell.00144.2012

Changes in plasma membrane Ca-ATPase and stromal interacting molecule 1 expression levels for Ca2+ signaling in dystrophic mdx mouse muscle.

2012

Journal Article

Growth hormone secretagogues protect mouse cardiomyocytes from in vitro ischemia/reperfusion injury through regulation of intracellular calcium

Ma, Yi, Zhang, Lin, Edwards, Joshua N., Launikonis, Breadley S. and Chen, Chen (2012). Growth hormone secretagogues protect mouse cardiomyocytes from in vitro ischemia/reperfusion injury through regulation of intracellular calcium. PLoS One, 7 (4) e35265, e35265.1-e35265.9. doi: 10.1371/journal.pone.0035265

Growth hormone secretagogues protect mouse cardiomyocytes from in vitro ischemia/reperfusion injury through regulation of intracellular calcium

Current funding

  • 2025 - 2026
    Membrane cholesterol in dysferlin-deficient muscle
    Jain Foundation
    Open grant
  • 2024 - 2027
    Heat regulation by the fibre types in muscle
    ARC Discovery Projects
    Open grant
  • 2022 - 2025
    Regulated muscle-based thermogenesis for body temperature regulation
    ARC Discovery Projects
    Open grant

Past funding

  • 2024 - 2025
    Membrane cholesterol in dysferlin-deficient muscle
    Jain Foundation
    Open grant
  • 2022 - 2023
    Leaky ryanodine receptors in dysferlinopathy
    Jain Foundation
    Open grant
  • 2022 - 2024
    cAMP-dependent modulation of calcium handling in skeletal muscle
    Research Donation Generic
    Open grant
  • 2020 - 2024
    Assessment of the ability of small molecule RyR modulators to correct the Ca2+ fluxes in skeletal muscle fibers with RyR myopathy
    RyR-1 Foundation
    Open grant
  • 2020 - 2023
    Sarcoplasmic reticulum-mitochondrial functional interactions in muscle
    ARC Discovery Projects
    Open grant
  • 2020 - 2023
    Diagnosing Malignant Hyperthermia from Muscle Fibres obtained from Needle Biopsy
    The Sydney Children's Hospitals Network (Randwick and Westmead) (Incorporating The Royal Alexandra Hospital For Children)
    Open grant
  • 2019 - 2020
    Ca2+ handling and tubular (t-) system function in dysferlinopathy
    Jain Foundation
    Open grant
  • 2019 - 2021
    Junctional membrane calcium dynamics in skeletal muscle fibres with ryanodine receptor variants
    AFM-Telethon Research Grant
    Open grant
  • 2018 - 2021
    Calcium cycling and heat generation in skeletal muscle fibres
    ARC Discovery Projects
    Open grant
  • 2015
    A state-of-the-art spinning disc confocal microscope for high speed imaging of live cells and super resolution microscopy
    UQ Major Equipment and Infrastructure
    Open grant
  • 2015 - 2018
    Physiological activation and targets of calcium signaling in muscle
    ARC Future Fellowships
    Open grant
  • 2014
    Cellular metabolic respirometry and enzymatic assessment suite
    UQ Major Equipment and Infrastructure
    Open grant
  • 2013
    Establishment of an Integrated Facility for Single Cell Analysis
    UQ Major Equipment and Infrastructure
    Open grant
  • 2013
    UQ Travel Awards Category 1 - Assoc/Professor Tom Shannon
    UQ Travel Grants Scheme
    Open grant
  • 2012 - 2013
    Identifying the pathways of excessive calcium leak in to dystrophic muscle
    Brain Foundation
    Open grant
  • 2012 - 2016
    Manipulating store-operated Ca2+ entry to improve muscle function in dystrophy
    NHMRC Project Grant
    Open grant
  • 2011 - 2013
    Gamma-Secretase inhibitors as novel pharmacological agents to target stroke-induced brain injury
    NHMRC Project Grant
    Open grant
  • 2011 - 2013
    Muscle fibre excitability and Ca2+ regulation in skeletal muscle of amphibians and mammals.
    ARC Discovery Projects
    Open grant
  • 2010 - 2012
    Improving muscle function in dystrophy
    UQ Collaboration and Industry Engagement Fund
    Open grant
  • 2010
    UQ Travel Awards Category 1, Thomas Shannon
    UQ Travel Grants Scheme
    Open grant
  • 2008 - 2009
    Maintaining calcium balance in healthy skeletal muscle and the deleterious changes with ageing and in dystrophy
    UQ Foundation Research Excellence Awards - DVC(R) Funding
    Open grant
  • 2008 - 2009
    Calcium regulation in the skeletal muscle triad and along the fibre.
    ARC Discovery Projects
    Open grant
  • 2008
    Membrane excitability and cellular calcium regulation in the peripheral nervous system under different (patho)-physiological conditions and in inflammatory disease
    ARC Linkage International
    Open grant
  • 2008
    Olympus disk-spinning confocal microscope system capable of simutaneously imaging a ratiometric (UV) non-ratiometric (visible range) dye
    Ramaciotti Foundation
    Open grant
  • 2008
    Understanding cell physiology by confocal laser scanning microscopy
    UQ Major Equipment and Infrastructure
    Open grant
  • 2007 - 2008
    Can local increases in cytoplasmic {Ca2+} trigger action potentials in the tubular system of skeletal muscle fibres?
    UQ New Staff Research Start-Up Fund
    Open grant
  • 2007 - 2008
    Control of Ca2+ release in excitation-contration coupling and its modulation by membrane cholesterol
    NHMRC Training (Postdoctoral) Fellowship
    Open grant
  • 2007 - 2010
    Store operated Ca2+ entry in skeletal fibres from normal and dystrophin-deficient muscle
    NHMRC Project Grant
    Open grant

Availability

Professor Bradley Launikonis is:
Available for supervision

Before you email them, read our advice on how to contact a supervisor.

Supervision history

Current supervision

  • Doctor Philosophy

    The influence of RyR modifications on the downstream mitochondrial Ca2+ handling

    Principal Advisor

    Other advisors: Dr David Simmons, Dr Daniel Singh

  • Doctor Philosophy

    The influence of RyR modifications on the downstream mitochondrial Ca2+ handling

    Principal Advisor

    Other advisors: Dr David Simmons, Dr Daniel Singh

  • Doctor Philosophy

    The influence of RyR modifications on the downstream mitochondrial Ca2+ handling

    Principal Advisor

    Other advisors: Dr David Simmons, Dr Daniel Singh

  • Doctor Philosophy

    Signalling between brown adipose tissue and skeletal muscle for body temperature maintenance.

    Principal Advisor

    Other advisors: Dr Daniel Singh

Completed supervision

Enquiries

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