Professor

Bradley Launikonis

Email: 
Phone: 
+61 7 336 54301

Availability

Professor Bradley Launikonis is:
Available for supervision

Fields of research

Biological Sciences Zoology

Qualifications

  • Doctor of Philosophy, La Trobe University

Search Professor Bradley Launikonis’s works on UQ eSpace

95 works between 1997 and 2025
All (95) Journal Article (71) Book Chapter (1) Conference Publication (23)

61 - 80 of 95 works

2012

Journal Article

Longitudinal and transversal propagation of excitation along the tubular system of rat fast-twitch muscle fibres studied by high speed confocal microscopy

Edwards, Joshua N., Cully, Tanya R., Shannon, Thomas R., Stephenson, D. George and Launikonis, Bradley S. (2012). Longitudinal and transversal propagation of excitation along the tubular system of rat fast-twitch muscle fibres studied by high speed confocal microscopy. Journal of Physiology, 590 (3), 475-491. doi: 10.1113/jphysiol.2011.221796

Longitudinal and transversal propagation of excitation along the tubular system of rat fast-twitch muscle fibres studied by high speed confocal microscopy

2012

Conference Publication

Different Capacity for Store-Operated Ca<SUP>2+</SUP> Entry and Ca<SUP>2+</SUP> Extrusion Across the Plasma Membrane of Wild-Type and Dystrophic mdx Mouse Muscle

Cully, Tanya R., Edwards, Joshua N., Murphy, Robyn M. and Launikonis, Bradley S. (2012). Different Capacity for Store-Operated Ca2+ Entry and Ca2+ Extrusion Across the Plasma Membrane of Wild-Type and Dystrophic mdx Mouse Muscle. 56th Annual Meeting of the Biophysical-Society, San Diego Ca, Feb 25-29, 2012. CAMBRIDGE: CELL PRESS. doi: 10.1016/j.bpj.2011.11.1989

Different Capacity for Store-Operated Ca<SUP>2+</SUP> Entry and Ca<SUP>2+</SUP> Extrusion Across the Plasma Membrane of Wild-Type and Dystrophic mdx Mouse Muscle

2012

Conference Publication

Injection of rAAV-Orai1 in adult wt and dystrophic mice up-regulates store operated calcium entry

Cully, T. R., Purdue, B. W., Thomas, W. G., Gregorevic, P. and Launikonis, B. S. (2012). Injection of rAAV-Orai1 in adult wt and dystrophic mice up-regulates store operated calcium entry. Collaborative Congress of the European-Society-of-Gene-and-Cell-Therapy/French-Society-of-Cell-and-Gene-Therapy, Versailles, France, 25-29 October 2012. New Rochelle, NY, United States: Mary Ann Liebert.

Injection of rAAV-Orai1 in adult wt and dystrophic mice up-regulates store operated calcium entry

2011

Journal Article

Store-operated calcium entry remains fully functional in aged mouse skeletal muscle despite a decline in STIM1 protein expression

Edwards, Joshua N., Blackmore, Daniel G., Gilbert, Daniel F., Murphy, Robyn M. and Launikonis, Bradley S. (2011). Store-operated calcium entry remains fully functional in aged mouse skeletal muscle despite a decline in STIM1 protein expression. Aging Cell, 10 (4), 675-685. doi: 10.1111/j.1474-9726.2011.00706.x

Store-operated calcium entry remains fully functional in aged mouse skeletal muscle despite a decline in STIM1 protein expression

2011

Conference Publication

Growth Hormone Secretagogues Preserved Normal Action Potential Pattern in Mouse Ischemia/reperfusion Cardiomyocytes In Vitro Through Modification of The Voltage-gated L Type Calcium Current and Transient Outward Potassium Current

Ma, Y, Zhang, L, Edwards, JN, Launikonis, B and Chen, C (2011). Growth Hormone Secretagogues Preserved Normal Action Potential Pattern in Mouse Ischemia/reperfusion Cardiomyocytes In Vitro Through Modification of The Voltage-gated L Type Calcium Current and Transient Outward Potassium Current. Scientific Sessions of High Blood Pressure Research, Orlando Fl, Sep 20-24, 2011. doi: 10.1161/HYP.0b013e318234a201

Growth Hormone Secretagogues Preserved Normal Action Potential Pattern in Mouse Ischemia/reperfusion Cardiomyocytes In Vitro Through Modification of The Voltage-gated L Type Calcium Current and Transient Outward Potassium Current

2010

Journal Article

Toward the roles of store-operated Ca(2+) entry in skeletal muscle

Launikonis, Bradley S., Murphy, Robyn M. and Edwards, Joshua N. (2010). Toward the roles of store-operated Ca(2+) entry in skeletal muscle. Pflugers Archiv - European Journal of Physiology, 460 (5), 813-823. doi: 10.1007/s00424-010-0856-7

Toward the roles of store-operated Ca(2+) entry in skeletal muscle

2010

Journal Article

Upregulation of store-operated Ca2+ entry in dystrophic mdx mouse muscle

Edwards, Joshua N., Friedrich, Oliver, Cully, Tanya R., von Wegner, Frederic, Murphy, Robyn M. and Launikonis, Bradley S. (2010). Upregulation of store-operated Ca2+ entry in dystrophic mdx mouse muscle. American Journal of Physiology: Cell Physiology, 299 (1), C42-C50. doi: 10.1152/ajpcell.00524.2009

Upregulation of store-operated Ca2+ entry in dystrophic mdx mouse muscle

2010

Journal Article

Ultra-rapid activation and deactivation of store-operated Ca2+ entry in skeletal muscle

Edwards, Joshua N., Murphy, Robyn M., Cully, Tanya R., von Wegner, Frederic, Friedrich, Oliver and Launikonis, Bradley S. (2010). Ultra-rapid activation and deactivation of store-operated Ca2+ entry in skeletal muscle. Cell Calcium, 47 (5), 458-467. doi: 10.1016/j.ceca.2010.04.001

Ultra-rapid activation and deactivation of store-operated Ca2+ entry in skeletal muscle

2009

Journal Article

Rapid Ca2+ flux through the transverse tubular membrane, activated by individual action potentials in mammalian skeletal muscle

Launikonis, Bradley S., Stephenson, D. George and Friedrich, Oliver (2009). Rapid Ca2+ flux through the transverse tubular membrane, activated by individual action potentials in mammalian skeletal muscle. Journal of Physiology, 587 (10), 2299-2312. doi: 10.1113/jphysiol.2009.168682

Rapid Ca2+ flux through the transverse tubular membrane, activated by individual action potentials in mammalian skeletal muscle

2008

Journal Article

Inhibitory control Over Ca2+ Sparks via Mechanosensitive Channels Is Disrupted in Dystrophin Deficient Muscle but Restored by Mini-Dystrophin Expression

Teichmann, M D H, Wegner, F, Fink, R H A, Chamberlain, J S, Launikonis, B S, Martinac, B and Friedrich, O (2008). Inhibitory control Over Ca2+ Sparks via Mechanosensitive Channels Is Disrupted in Dystrophin Deficient Muscle but Restored by Mini-Dystrophin Expression. PLoS One, 3 (11) e3644, 1-16. doi: 10.1371/journal.pone.0003644

Inhibitory control Over Ca2+ Sparks via Mechanosensitive Channels Is Disrupted in Dystrophin Deficient Muscle but Restored by Mini-Dystrophin Expression

2008

Journal Article

The accessibility and interconnectivity of the tubular system network in toad skeletal muscle

Edwards, Joshua N. and Launikonis, Bradley S. (2008). The accessibility and interconnectivity of the tubular system network in toad skeletal muscle. The Jounal of Physiology, 586 (21), 5077-5089. doi: 10.1113/jphysiol.2008.155127

The accessibility and interconnectivity of the tubular system network in toad skeletal muscle

2008

Journal Article

Calcium-dependent inactivation terminates calcium release in skeletal muscle of amphibians

Rios, E., Zhou, J., Brum, G., Launikonis, B. S. and Stern, M. D. (2008). Calcium-dependent inactivation terminates calcium release in skeletal muscle of amphibians. Journal of General Physiology, 131 (4), 335-348. doi: 10.1085/jgp.200709870

Calcium-dependent inactivation terminates calcium release in skeletal muscle of amphibians

2007

Journal Article

An action potential (AP)-activated Ca2+ current in the tubular system of mammalian skeletal muscle.

Launikonis, B, Stephenson, DG and Rios, E (2007). An action potential (AP)-activated Ca2+ current in the tubular system of mammalian skeletal muscle.. Biophysical Journal, 79A-79A.

An action potential (AP)-activated Ca2+ current in the tubular system of mammalian skeletal muscle.

2007

Journal Article

Dynamic regulation of the large exocytotic fusion pore in pancreatic acinar cells

Larina, O., Bhat, P., Pickett, J. A., Launikonis, B. S., Shah, A., Kruger, W. A., Edwardson, J. M. and Thorn, P. (2007). Dynamic regulation of the large exocytotic fusion pore in pancreatic acinar cells. Molecular Biology of The Cell, 18 (9), 3502-3511. doi: 10.1091/mbc.E07-01-0024

Dynamic regulation of the large exocytotic fusion pore in pancreatic acinar cells

2007

Journal Article

Store-operated Ca2+ entry during intracellular Ca2+ release in mammalian skeletal muscle

Launikonis, BS and Rios, E (2007). Store-operated Ca2+ entry during intracellular Ca2+ release in mammalian skeletal muscle. Journal of Physiology-london, 583 (1), 81-97. doi: 10.1113/jphysiol.2007.135046

Store-operated Ca2+ entry during intracellular Ca2+ release in mammalian skeletal muscle

2006

Journal Article

The changes in Ca2+ sparks associated with measured modifications of intra-store Ca2+ concentration in skeletal muscle

Launikonis, Bradley S., Zhou, Jingsong, Santiago, Demetrio, Brum, Gustavo and Rios, Eduardo (2006). The changes in Ca2+ sparks associated with measured modifications of intra-store Ca2+ concentration in skeletal muscle. Journal of General Physiology, 128 (1), 45-54. doi: 10.1085/jgp.200609545

The changes in Ca2+ sparks associated with measured modifications of intra-store Ca2+ concentration in skeletal muscle

2006

Journal Article

The elusive role of store depletion in the control of intracellular calcium release

Rios, E., Launikonis, B. S., Royer, L., Brum, G. and Zhou, J (2006). The elusive role of store depletion in the control of intracellular calcium release. Journal of Muscle Research And Cell Motility, 27 (5-7), 337-350. doi: 10.1007/s10974-006-9082-5

The elusive role of store depletion in the control of intracellular calcium release

2006

Journal Article

Erratum: A probable role of dihydropyridine receptors in repression of Ca2+ sparks demonstrated in cultured mammalian muscle (American Journal of Physiology - Cell Physiology (539-553) DOI: 10.1152/ajpcell.00592. 2004)

Zhou, J., Yi, J., Royer, L., Launikonis, B. S., González, A., García, J. and Ríos, E. (2006). Erratum: A probable role of dihydropyridine receptors in repression of Ca2+ sparks demonstrated in cultured mammalian muscle (American Journal of Physiology - Cell Physiology (539-553) DOI: 10.1152/ajpcell.00592. 2004). American Journal of Physiology - Cell Physiology, 290 (5) doi: 10.1152/ajpcell.00054.2006

Erratum: A probable role of dihydropyridine receptors in repression of Ca2+ sparks demonstrated in cultured mammalian muscle (American Journal of Physiology - Cell Physiology (539-553) DOI: 10.1152/ajpcell.00592. 2004)

2006

Journal Article

A probable role of dihydropyridine receptors in repression of Ca2+ sparks demonstrated in cultured mammalian muscle

Zhou, Jingsong, Yi, Jianxun, Royer, Leandro, Launikonis, Bradley S., Gonzalez, Adom, Garcia, Jesus and Rios, Eduardo (2006). A probable role of dihydropyridine receptors in repression of Ca2+ sparks demonstrated in cultured mammalian muscle. American Journal of Physiology - Cell Physiology, 290 (2), C539-C553. doi: 10.1152/ajpcell.00592.2004

A probable role of dihydropyridine receptors in repression of Ca2+ sparks demonstrated in cultured mammalian muscle

2006

Journal Article

Depletion "skraps" and dynamic buffering inside the cellular calcium store

Launikonis, B. S., Zhou, J. S., Royer, L., Shannon, T. R., Brum, G. and Rios, E. (2006). Depletion "skraps" and dynamic buffering inside the cellular calcium store. Proceedings of The National Academy of Sciences of The United States of America, 103 (8), 2982-2987. doi: 10.1073/pnas.0511252103

Depletion "skraps" and dynamic buffering inside the cellular calcium store

Current funding

  • 2025 - 2026
    Membrane cholesterol in dysferlin-deficient muscle
    Jain Foundation
    Open grant
  • 2024 - 2027
    Heat regulation by the fibre types in muscle
    ARC Discovery Projects
    Open grant
  • 2022 - 2025
    Regulated muscle-based thermogenesis for body temperature regulation
    ARC Discovery Projects
    Open grant

Past funding

  • 2024 - 2025
    Membrane cholesterol in dysferlin-deficient muscle
    Jain Foundation
    Open grant
  • 2022 - 2023
    Leaky ryanodine receptors in dysferlinopathy
    Jain Foundation
    Open grant
  • 2022 - 2024
    cAMP-dependent modulation of calcium handling in skeletal muscle
    Research Donation Generic
    Open grant
  • 2020 - 2024
    Assessment of the ability of small molecule RyR modulators to correct the Ca2+ fluxes in skeletal muscle fibers with RyR myopathy
    RyR-1 Foundation
    Open grant
  • 2020 - 2023
    Sarcoplasmic reticulum-mitochondrial functional interactions in muscle
    ARC Discovery Projects
    Open grant
  • 2020 - 2023
    Diagnosing Malignant Hyperthermia from Muscle Fibres obtained from Needle Biopsy
    The Sydney Children's Hospitals Network (Randwick and Westmead) (Incorporating The Royal Alexandra Hospital For Children)
    Open grant
  • 2019 - 2020
    Ca2+ handling and tubular (t-) system function in dysferlinopathy
    Jain Foundation
    Open grant
  • 2019 - 2021
    Junctional membrane calcium dynamics in skeletal muscle fibres with ryanodine receptor variants
    AFM-Telethon Research Grant
    Open grant
  • 2018 - 2021
    Calcium cycling and heat generation in skeletal muscle fibres
    ARC Discovery Projects
    Open grant
  • 2015
    A state-of-the-art spinning disc confocal microscope for high speed imaging of live cells and super resolution microscopy
    UQ Major Equipment and Infrastructure
    Open grant
  • 2015 - 2018
    Physiological activation and targets of calcium signaling in muscle
    ARC Future Fellowships
    Open grant
  • 2014
    Cellular metabolic respirometry and enzymatic assessment suite
    UQ Major Equipment and Infrastructure
    Open grant
  • 2013
    Establishment of an Integrated Facility for Single Cell Analysis
    UQ Major Equipment and Infrastructure
    Open grant
  • 2013
    UQ Travel Awards Category 1 - Assoc/Professor Tom Shannon
    UQ Travel Grants Scheme
    Open grant
  • 2012 - 2013
    Identifying the pathways of excessive calcium leak in to dystrophic muscle
    Brain Foundation
    Open grant
  • 2012 - 2016
    Manipulating store-operated Ca2+ entry to improve muscle function in dystrophy
    NHMRC Project Grant
    Open grant
  • 2011 - 2013
    Gamma-Secretase inhibitors as novel pharmacological agents to target stroke-induced brain injury
    NHMRC Project Grant
    Open grant
  • 2011 - 2013
    Muscle fibre excitability and Ca2+ regulation in skeletal muscle of amphibians and mammals.
    ARC Discovery Projects
    Open grant
  • 2010 - 2012
    Improving muscle function in dystrophy
    UQ Collaboration and Industry Engagement Fund
    Open grant
  • 2010
    UQ Travel Awards Category 1, Thomas Shannon
    UQ Travel Grants Scheme
    Open grant
  • 2008 - 2009
    Maintaining calcium balance in healthy skeletal muscle and the deleterious changes with ageing and in dystrophy
    UQ Foundation Research Excellence Awards - DVC(R) Funding
    Open grant
  • 2008 - 2009
    Calcium regulation in the skeletal muscle triad and along the fibre.
    ARC Discovery Projects
    Open grant
  • 2008
    Membrane excitability and cellular calcium regulation in the peripheral nervous system under different (patho)-physiological conditions and in inflammatory disease
    ARC Linkage International
    Open grant
  • 2008
    Olympus disk-spinning confocal microscope system capable of simutaneously imaging a ratiometric (UV) non-ratiometric (visible range) dye
    Ramaciotti Foundation
    Open grant
  • 2008
    Understanding cell physiology by confocal laser scanning microscopy
    UQ Major Equipment and Infrastructure
    Open grant
  • 2007 - 2008
    Can local increases in cytoplasmic {Ca2+} trigger action potentials in the tubular system of skeletal muscle fibres?
    UQ New Staff Research Start-Up Fund
    Open grant
  • 2007 - 2008
    Control of Ca2+ release in excitation-contration coupling and its modulation by membrane cholesterol
    NHMRC Training (Postdoctoral) Fellowship
    Open grant
  • 2007 - 2010
    Store operated Ca2+ entry in skeletal fibres from normal and dystrophin-deficient muscle
    NHMRC Project Grant
    Open grant

Availability

Professor Bradley Launikonis is:
Available for supervision

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Supervision history

Current supervision

  • Doctor Philosophy

    The influence of RyR modifications on the downstream mitochondrial Ca2+ handling

    Principal Advisor

    Other advisors: Dr David Simmons, Dr Daniel Singh

  • Doctor Philosophy

    The influence of RyR modifications on the downstream mitochondrial Ca2+ handling

    Principal Advisor

    Other advisors: Dr David Simmons, Dr Daniel Singh

  • Doctor Philosophy

    The influence of RyR modifications on the downstream mitochondrial Ca2+ handling

    Principal Advisor

    Other advisors: Dr David Simmons, Dr Daniel Singh

  • Doctor Philosophy

    Signalling between brown adipose tissue and skeletal muscle for body temperature maintenance.

    Principal Advisor

    Other advisors: Dr Daniel Singh

Completed supervision

Enquiries

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