Overview
Background
Dr Adam Walker received his BSc(Hons) in Biochemistry from the University of Tasmania, and PhD in Neuroscience from the Florey Institute of Neuroscience and Mental Health at the University of Melbourne, focused on understanding the molecular mechanisms of motor neuron disease (MND). He undertook a postdoctoral fellowship with Professor Virginia Lee at the Center for Neurodegenerative Disease Research, University of Pennsylvania (2011-2015), developing new transgenic TDP-43 mouse models of disease. Dr Walker was previously an NHMRC CJ Martin Overseas Biomedical Research Fellow and was awarded an NHMRC RD Wright Career Development Fellowship (2018-2022), to continue his research on neurodegenerative diseases.
He was Group Leader in the Clem Jones Centre for Ageing Dementia Research at the Queensland Brain Institute 2018-2025, and is now Honorary Professor.
Availability
- Professor Adam Walker is:
- Not available for supervision
Fields of research
Qualifications
- Doctor of Philosophy, University of Melbourne
Research interests
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Motor neuron disease (MND)/amyotrophic lateral sclerosis (ALS)
Molecular mechanisms of disease and pre-clinical studies in model systems.
Works
Search Professor Adam Walker’s works on UQ eSpace
2009
Journal Article
A functional genomics approach reveals novel quantitative trait loci associated with platelet signaling pathways
Jones, Chris I., Bray, Sarah, Garner, Stephen F., Stephens, Jonathan, de Bono, Bernard, Angenent, Will G. J., Bentley, David, Burns, Philippa, Coffey, Alison, Deloukas, Panos, Earthrowl, Mark, Farndale, Richard W., Hoylaerts, Marc F., Koch, Kerstin, Rankin, Angela, Rice, Catherine M., Rogers, Jane, Samani, Nilesh J., Steward, Michael, Walker, Adam, Watkins, Nicholas A., Akkerman, Jan-Willem, Dudbridge, Frank, Goodall, Alison H. and Ouwehand, Willem H. (2009). A functional genomics approach reveals novel quantitative trait loci associated with platelet signaling pathways. Blood, 114 (7), 1405-1416. doi: 10.1182/blood-2009-02-202614
2009
Journal Article
Differential Expression of Vascular Endothelial Growth Factor, and Angiopoietin 1 and 2 in Functionally Divergent Experimental Rabbit Models of Bladder Hypertrophy
Walker, Adam, Tanner, Matthew J., Husson, Paul, Schuler, Catherine, Kogan, Barry A., Buttyan, Ralph and Levin, Robert M. (2009). Differential Expression of Vascular Endothelial Growth Factor, and Angiopoietin 1 and 2 in Functionally Divergent Experimental Rabbit Models of Bladder Hypertrophy. Journal of Urology, 181 (6), 2790-2796. doi: 10.1016/j.juro.2009.01.100
2009
Journal Article
Functional genomics in zebrafish permits rapid characterization of novel platelet membrane proteins
O'Connor, Marie N., Salles, Isabelle I., Cvejic, Ana, Watkins, Nicholas A., Walker, Adam, Garner, Stephen F., Jones, Chris I., Macaulay, Iain C., Steward, Michael, Zwaginga, Jaap-Jan, Bray, Sarah L., Dudbridge, Frank, de Bono, Bernard, Goodall, Alison H., Deckmyn, Hans, Stemple, Derek L. and Ouwehand, Willem H. (2009). Functional genomics in zebrafish permits rapid characterization of novel platelet membrane proteins. Blood, 113 (19), 4754-4762. doi: 10.1182/blood-2008-06-162693
2009
Journal Article
Single domain antibodies against the collagen signalling receptor glycoprotein VI are inhibitors of collagen induced thrombus formation
Walker, Adam, Pugh, Nicholas, Garner, Stephen F., Stephens, Jonathan, Maddox, Ben, Ouwehand, Willem H., Farndale, Richard W. and Steward, Michael (2009). Single domain antibodies against the collagen signalling receptor glycoprotein VI are inhibitors of collagen induced thrombus formation. Platelets, 20 (4) PII 911474177, 268-276. doi: 10.1080/09537100902893792
2008
Conference Publication
Functional Genomics in Zebrafish Permits Rapid Characterization of Novel Platelet Membrane Proteins
Salles, Isabelle I., O'Connor, Marie N., Watkins, Nicholas A., Walker, Adam, Garner, Stephen F., Jones, Chris I., Macauley, Iain, Steward, Michael, Zwaginga, Jaap Jan, Bray, Sarah L., Cvejic, Ana, Dudbridge, Frank, de Bono, Bernard, Deckmyn, Hans, Stemple, Derek L. and Ouwehand, Willem (2008). Functional Genomics in Zebrafish Permits Rapid Characterization of Novel Platelet Membrane Proteins. 50th Annual Meeting of the American-Society-of-Hematology, San Francisco Ca, Dec 06-09, 2008. WASHINGTON: AMER SOC HEMATOLOGY.
2008
Journal Article
Redefining the role of metallothionein within the injured brain: Extracellular metallothioneins play an important role in the astrocyte-neuron response to injury
Chung, Roger S., Penkowa, Milena, Dittmann, Justin, King, Carolyn E., Bartlett, Carole, Asmussen, Johanne W., Hidalgo, Juan, Carrasco, Javier, Leung, Yee Kee J., Walker, Adam K., Fung, Samantha J., Dunlop, Sarah A., Fitzgerald, Melinda, Beazley, Lyn D., Chuah, Meng I., Vickers, James C. and West, Adrian K. (2008). Redefining the role of metallothionein within the injured brain: Extracellular metallothioneins play an important role in the astrocyte-neuron response to injury. Journal of Biological Chemistry, 283 (22), 15349-15358. doi: 10.1074/jbc.M708446200
2007
Journal Article
Metallothionein expression by NG2 glial cells following CNS injury
Chung, R. S., Fung, S. J., Leung, Y. K., Walker, A. K., McCormack, G. H., Chuah, M. I., Vickers, J. C. and West, A. K. (2007). Metallothionein expression by NG2 glial cells following CNS injury. Cellular and Molecular Life Sciences, 64 (19-20), 2716-2722. doi: 10.1007/s00018-007-7267-8
Funding
Current funding
Past funding
Supervision
Availability
- Professor Adam Walker is:
- Not available for supervision
Supervision history
Current supervision
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Doctor Philosophy
Mechanism underpinning TDP43 aggregation
Associate Advisor
Other advisors: Dr Rachel Gormal, Dr Adekunle Bademosi, Professor Frederic Meunier
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Doctor Philosophy
The effects of metabolic perturbations on the development of fatigue in Amyotrophic Lateral Sclerosis
Associate Advisor
Other advisors: Associate Professor Frederik Steyn, Associate Professor Shyuan Ngo
Completed supervision
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2026
Doctor Philosophy
The role and regulation of TDP-43 phosphorylation in the pathogenesis of ALS and FTD
Principal Advisor
Other advisors: Dr Adekunle Bademosi
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2025
Doctor Philosophy
Investigating novel modulators of TDP-43 pathology within the context of ALS and FTD
Principal Advisor
Other advisors: Dr Rebecca San Gil
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2025
Doctor Philosophy
Molecular elucidation of TDP-43 co-aggregators in models of ALS/FTD
Principal Advisor
Other advisors: Professor Massimo Hilliard
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2025
Doctor Philosophy
TDP-43 and protein clearance in the pathogenesis and treatment of ALS and FTD
Principal Advisor
Other advisors: Dr Rebecca San Gil
-
2025
Doctor Philosophy
From Shields to Scaffolds - Perineuronal Nets in Neuroprotection and Neuroplasticity
Associate Advisor
Other advisors: Associate Professor Mark Bellingham, Associate Professor Peter Noakes
Media
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