Overview
Background
Professor Obermair is the Director of Queensland Centre for Gynaecological Cancer Research (QCGC Research). He is a Professor of Gynaecological Oncology since 2007, a Senior Medical Officer at Royal Brisbane & Women’s Hospital and a Visiting Medical Officer at St Andrews War Memorial Hospital and Buderim Private Hospital. He holds an Honorary title of Professor at UQ since 2006.
Professor Obermair is an internationally recognised leader in gynaecological oncology research and treatment and has lead the research team at QCGC Research since establishing it in 2003.
Availability
- Professor Andreas Obermair is:
- Available for supervision
Fields of research
Qualifications
- Doctoral Diploma of Medicine, International University Vienna
- Royal Australian and New Zealand College of Obstetricians and Gynaecologists, Royal Australian and New Zealand College of Obstetricians and Gynaecologists
Research interests
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Clinical Trials
Decisions on cancer management ideally are based on the results of high-level evidence, obtained through clinical trials whenever possible. As a principle, a new (proposed better) intervention should be compared to the current standard treatment before being made available generally. Outside a clinical trial new treatments should not become available until evidence has become available to demonstrate superiority over the current standard treatment. Retrospective studies harbour the risk that biases influenced outcomes. At QCGC Research we engage in phase 2 and 3 clinical trials. In large phase trials, patients are allocated randomly to one of two or more interventions in order to minimise the risk of bias. Generally, patients treated within clinical trials have a better outcome compared to patients who are not treated in clinical trials. As the Director of Research Gynaecological Oncology I am currently involved in developing and managing clinical trials in gynaecological cancers.
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Translational Research
The focus of QCGC Research's translational research program is the application of new technology (molecular, biochemical, imaging and surgical) to prevention, detection and therapy for gynaecological cancers.
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Quality of Life Research
Cancer specialists are aware that not only the survival time but also the quality of life is a key factor in cancer treatment. This is especially important when two treatments are equally effective but cause different side-effects. My Quality-of-Life research focuses on ovarian, endometrial, cervical and vulval cancer. I wish to provide the best, most effective and modern treatment to my patients with least possible detriments to quality of life.
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Minimally Invasive Surgery
In Australia, around 30,000 hysterectomies are conducted annually to treat uterine cancer and various benign gynaecological conditions. While open abdominal surgery may be necessary in around 10% of cases, evidence shows that less-invasive approaches, such as total laparoscopic hysterectomy (TLH) can achieve better outcomes for women at a lower overall cost to the health system. Yet, in Queensland, four of ten hysterectomies are still conducted by open abdominal surgery. Our own research has shown that many Australian surgeons are keen to adopt new techniques such as TLH, but that the lack of systematic training and mentoring opportunities is the main impediment to practice-change. Together with gynaecological surgical teams at hospitals and industry support we developed a prototype for system-level transformative practice change in gynaecological surgery.
Research impacts
Professor Obermair is an innovative and skilled gynaecologic oncologist, surgical teacher and consumer advocate. His international leadership and research impact was acknowledged in 2020 by the Australian community, when he was awarded an NHMRC Investigator Fellowship Level 2 (2021-25). The national impact of his research was recognised in 2017, when he was awarded Cancer Australia’s Jeannie Ferris Recognition Award (2017), for outstanding achievements in clinical practice and research. He is deeply engaged in consumer involvement and co-founded and serves on the Board of the Cherish Foundation, a consumer-focussed organisation that funds clinical research in better treatments for women with gynaecological cancers.
Works
Search Professor Andreas Obermair’s works on UQ eSpace
2022
Journal Article
Patient experiences of conservative treatment for early stage endometrial cancer and endometrial hyperplasia with atypia using levonorgestrel intrauterine device: a qualitative study
O'Hara, Montana, Janda, Monika, McCarthy, Alexandra L., Nicklin, James, Walker, Graeme and Obermair, Andreas (2022). Patient experiences of conservative treatment for early stage endometrial cancer and endometrial hyperplasia with atypia using levonorgestrel intrauterine device: a qualitative study. Gynecologic Oncology Reports, 39 100914, 100914. doi: 10.1016/j.gore.2021.100914
2022
Journal Article
Evaluating patient-reported symptoms and late adverse effects following completion of first-line chemotherapy for ovarian cancer using the MOST (Measure of Ovarian Symptoms and Treatment concerns)
Beesley, Vanessa L., Ross, Tanya L., King, Madeleine T., Campbell, Rachel, Nagle, Christina M., Obermair, Andreas, Grant, Peter, DeFazio, Anna, Webb, Penelope M. and Friedlander, Michael L. (2022). Evaluating patient-reported symptoms and late adverse effects following completion of first-line chemotherapy for ovarian cancer using the MOST (Measure of Ovarian Symptoms and Treatment concerns). Gynecologic Oncology, 164 (2), 437-445. doi: 10.1016/j.ygyno.2021.12.006
2022
Journal Article
Post-recurrence survival in patients with cervical cancer
Cibula, David, Dostálek, Lukáš, Jarkovsky, Jiri, Mom, Constantijne H., Lopez, Aldo, Falconer, Henrik, Scambia, Giovanni, Ayhan, Ali, Kim, Sarah H., Isla Ortiz, David, Klat, Jaroslav, Obermair, Andreas, Di Martino, Giampaolo, Pareja, Rene, Manchanda, Ranjit, Kosťun, Jan, dos Reis, Ricardo, Meydanli, Mehmet Mutlu, Odetto, Diego, Laky, Rene, Zapardiel, Ignacio, Weinberger, Vit, Benešová, Klára, Borčinová, Martina, Cardenas, Fernando, Wallin, Emelie, Pedone Anchora, Luigi, Akilli, Huseyin, Abu-Rustum, Nadeem R. ... van Lonkhuijzen, Luc R.C.W. (2022). Post-recurrence survival in patients with cervical cancer. Gynecologic Oncology, 164 (2), 362-369. doi: 10.1016/j.ygyno.2021.12.018
2021
Journal Article
Fertility-sparing management of early-stage endometrial cancer in reproductive age women: current treatment outcomes and future directions
Janda, Monika and Obermair, Andreas (2021). Fertility-sparing management of early-stage endometrial cancer in reproductive age women: current treatment outcomes and future directions. International Journal of Gynecological Cancer, 31 (12) ijgc-2021-003192, 1506-1507. doi: 10.1136/ijgc-2021-003192
2021
Journal Article
A phase III randomized clinical trial comparing sentinel node biopsy with no retroperitoneal node dissection in apparent early-stage endometrial cancer – ENDO-3: ANZGOG trial 1911/2020
Obermair, Andreas, Nicklin, Jim, Gebski, Val, Hayes, Sandra C., Graves, Nicholas, Mileshkin, Linda, Lin, Ming Yin, Beale, Phillip, Baxter, Eva, Robledo, Kristy, Salomon, Carlos, Hanna, George B. and Janda, Monika (2021). A phase III randomized clinical trial comparing sentinel node biopsy with no retroperitoneal node dissection in apparent early-stage endometrial cancer – ENDO-3: ANZGOG trial 1911/2020. International Journal of Gynecologic Cancer, 31 (12) ijgc-2021-003029, 1595-1601. doi: 10.1136/ijgc-2021-003029
2021
Journal Article
The annual recurrence risk model for tailored surveillance strategy in patients with cervical cancer
Cibula, David, Dostálek, Lukáš, Jarkovsky, Jiri, Mom, Constantijne H., Lopez, Aldo, Falconer, Henrik, Fagotti, Anna, Ayhan, Ali, Kim, Sarah H., Isla Ortiz, David, Klat, Jaroslav, Obermair, Andreas, Landoni, Fabio, Rodriguez, Juliana, Manchanda, Ranjit, Kosťun, Jan, dos Reis, Ricardo, Meydanli, Mehmet M., Odetto, Diego, Laky, Rene, Zapardiel, Ignacio, Weinberger, Vit, Benešová, Klára, Borčinová, Martina, Pari, Darwin, Salehi, Sahar, Bizzarri, Nicolò, Akilli, Huseyin, Abu-Rustum, Nadeem R. ... van Lonkhuijzen, Luc R.C.W. (2021). The annual recurrence risk model for tailored surveillance strategy in patients with cervical cancer. European Journal of Cancer, 158, 111-122. doi: 10.1016/j.ejca.2021.09.008
2021
Journal Article
Insights into ovarian cancer care: report from the ANZGOG Ovarian Cancer Webinar Series 2020
Obermair, Andreas, Beale, Philip, Scott, Clare L, Beshay, Victoria, Kichenadasse, Ganessan, Simcock, Bryony, Nicklin, James, Lee, Yeh Chen, Cohen, Paul and Meniawy, Tarek (2021). Insights into ovarian cancer care: report from the ANZGOG Ovarian Cancer Webinar Series 2020. Journal of Gynecologic Oncology, 32 (6) e95, e95. doi: 10.3802/jgo.2021.32.e95
2021
Journal Article
Extracellular vesicle-associated miRNAs and chemoresistance: a systematic review
Campos, America, Sharma, Shayna, Obermair, Andreas and Salomon, Carlos (2021). Extracellular vesicle-associated miRNAs and chemoresistance: a systematic review. Cancers, 13 (18) 4608, 4608. doi: 10.3390/cancers13184608
2021
Journal Article
1429Impact of BRCA mutation status and lifestyle factors on survival among women with ovarian cancer
Gersekowski, Kate, Jordan, Susan, Delahunty, Rachel, Alsop, Kathryn, Goode, Ellen L, Bowtell, David, DeFazio, Anna, Friedlander, Michael, Obermair, Andreas, Grant, Peter and Group, Penelope Webb The OPAL Study (2021). 1429Impact of BRCA mutation status and lifestyle factors on survival among women with ovarian cancer. International Journal of Epidemiology, 50 (Supplement_1). doi: 10.1093/ije/dyab168.217
2021
Journal Article
Development of a multi-institutional prediction model for three-year survival status in patients with uterine leiomyosarcoma (AGOG11-022/QCGC1302 study)
Tse, Ka-Yu, Wong, Richard Wing-Cheuk, Chao, Angel, Ueng, Shir-Hwa, Yang, Lan-Yan, Cummings, Margaret, Smith, Deborah, Lai, Chiung-Ru, Lau, Hei-Yu, Yen, Ming-Shyen, Cheung, Annie Nga-Yin, Leung, Charlotte Ka-Lun, Chan, Kit-Sheung, Chan, Alice Ngot-Htain, Li, Wai-Hon, Choi, Carmen Ka-Man, Pong, Wai-Mei, Hui, Hoi-Fong, Yuk, Judy Ying-Wah, Yao, Hung, Yuen, Nancy Wah-Fun, Obermair, Andreas, Lai, Chyong-Huey, Ip, Philip Pun-Ching and Ngan, Hextan Yuen-Sheung (2021). Development of a multi-institutional prediction model for three-year survival status in patients with uterine leiomyosarcoma (AGOG11-022/QCGC1302 study). Cancers, 13 (10) 2378, 2378. doi: 10.3390/cancers13102378
2021
Journal Article
Development of a surgical competency assessment tool for sentinel lymph node dissection by minimally invasive surgery for endometrial cancer
Moloney, Kristen, Janda, Monika, Frumovitz, Michael, Leitao, Mario, Abu-Rustum, Nadeem R., Rossi, Emma, Nicklin, James L., Plante, Marie, Lecuru, Fabrice R., Buda, Alessandro, Mariani, Andrea, Leung, Yee, Ferguson, Sarah Elizabeth, Pareja, Rene, Kimmig, Rainer, Tong, Pearl Shuang Ye, McNally, Orla, Chetty, Naven, Liu, Kaijiang, Jaaback, Ken, Lau, Julio, Ng, Soon Yau Joseph, Falconer, Henrik, Persson, Jan, Land, Russell, Martinelli, Fabio, Garrett, Andrea, Altman, Alon, Pendlebury, Adam ... Obermair, Andreas (2021). Development of a surgical competency assessment tool for sentinel lymph node dissection by minimally invasive surgery for endometrial cancer. International Journal of Gynecological Cancer, 31 (5), 647-655. doi: 10.1136/ijgc-2020-002315
2021
Journal Article
Paucity of data evaluating patient centred outcomes following sentinel lymph node dissection in endometrial cancer: a systematic review
Obermair, Helena M., O'Hara, Montana, Obermair, Andreas and Janda, Monika (2021). Paucity of data evaluating patient centred outcomes following sentinel lymph node dissection in endometrial cancer: a systematic review. Gynecologic Oncology Reports, 36 100763, 100763. doi: 10.1016/j.gore.2021.100763
2021
Journal Article
Complete pathological response following levonorgestrel intrauterine device in clinically stage 1 endometrial adenocarcinoma: results of a randomized clinical trial
Janda, Monika, Robledo, Kristy P., Gebski, Val, Armes, Jane E., Alizart, Michelle, Brennan, Donal, Cummings, Margaret, Chen, Chen, Leung, Yee, Sykes, Peter, McNally, Orla, Oehler, Martin K., Walker, Graeme, Garrett, Andrea, Tang, Amy, Land, Russell, Nicklin, James L., Chetty, Naven, Perrin, Lewis C., Hoet, Greet, Sowden, Katherine, Eva, Lois, Tristram, Amanda and Obermair, Andreas (2021). Complete pathological response following levonorgestrel intrauterine device in clinically stage 1 endometrial adenocarcinoma: results of a randomized clinical trial. Gynecologic Oncology, 161 (1), 143-151. doi: 10.1016/j.ygyno.2021.01.029
2021
Journal Article
Physical activity levels among ovarian cancer survivors: a prospective longitudinal cohort study
Jones, Tamara, Sandler, Carolina, Vagenas, Dimitrios, Janda, Monika, Obermair, Andreas and Hayes, Sandra (2021). Physical activity levels among ovarian cancer survivors: a prospective longitudinal cohort study. International Journal of Gynecological Cancer, 31 (4), 553-561. doi: 10.1136/ijgc-2020-002107
2021
Journal Article
Corrigendum to “Complete pathological response following levonorgestrel intrauterine device in clinically stage 1 endometrial adenocarcinoma: Results of a randomized clinical trial” [Gynecologic Oncology 161 (2021) 143–151](S0090825821000895)(10.1016/j.ygyno.2021.01.029)
Janda, Monika, Robledo, Kristy P., Gebski, Val, Armes, Jane E., Alizart, Michelle, Brennan, Donal, Cummings, Margaret, Chen, Chen, Leung, Yee, Sykes, Peter, McNally, Orla, Oehler, Martin K., GraemeWalker, , Garrett, Andrea, Tang, Amy, Land, Russell, Nicklin, James L., Chetty, Naven, Perrin, Lewis C., Hoet, Greet, Sowden, Katherine, Eva, Lois, Tristram, Amanda and Obermair, Andreas (2021). Corrigendum to “Complete pathological response following levonorgestrel intrauterine device in clinically stage 1 endometrial adenocarcinoma: Results of a randomized clinical trial” [Gynecologic Oncology 161 (2021) 143–151](S0090825821000895)(10.1016/j.ygyno.2021.01.029). Gynecologic Oncology, 162 (2), 526-526. doi: 10.1016/j.ygyno.2021.05.016
2021
Journal Article
Refined cut-off for TP53 immunohistochemistry improves prediction of TP53 mutation status in ovarian mucinous tumors: implications for outcome analyses
Kang, Eun Young, Cheasley, Dane, LePage, Cecile, Wakefield, Matthew J., da Cunha Torres, Michelle, Rowley, Simone, Salazar, Carolina, Xing, Zhongyue, Allan, Prue, Bowtell, David D. L., Mes-Masson, Anne-Marie, Provencher, Diane M., Rahimi, Kurosh, Kelemen, Linda E., Fasching, Peter A., Doherty, Jennifer A., Goodman, Marc T., Goode, Ellen L., Deen, Suha, Pharoah, Paul D. P., Brenton, James D., Sieh, Weiva, Mateoiu, Constantina, Sundfeldt, Karin, Cook, Linda S., Le, Nhu D., Anglesio, Michael S., Gilks, C. Blake, Huntsman, David G. ... Campbell, Ian G. (2021). Refined cut-off for TP53 immunohistochemistry improves prediction of TP53 mutation status in ovarian mucinous tumors: implications for outcome analyses. Modern Pathology, 34 (1), 194-206. doi: 10.1038/s41379-020-0618-9
2020
Journal Article
Long-term quality of life outcomes of women treated for early-stage endometrial cancer
Sanjida, Saira, Obermair, Andreas, Gebski, Val, Armfield, Nigel and Janda, Monika (2020). Long-term quality of life outcomes of women treated for early-stage endometrial cancer. International Journal of Gynecologic Cancer, 31 (4), 530-536. doi: 10.1136/ijgc-2020-002145
2020
Journal Article
Survival outcomes after delayed cytoreduction surgery following neoadjuvant chemotherapy in advanced epithelial ovarian cancer
Yao, Shih-Ern, Tripcony, Lee, Sanday, Karen, Robertson, Jessica, Perrin, Lewis, Chetty, Naven, Land, Russell, Garrett, Andrea, Obermair, Andreas, Nascimento, Marcelo, Tang, Amy, Jagasia, Nisha, Singh, Piksi and Nicklin, Jim (2020). Survival outcomes after delayed cytoreduction surgery following neoadjuvant chemotherapy in advanced epithelial ovarian cancer. International Journal of Gynecological Cancer, 30 (12), 1935-1942. doi: 10.1136/ijgc-2020-001658
2020
Journal Article
When will I feel normal again? Trajectories and predictors of persistent symptoms and poor wellbeing after primary chemotherapy for ovarian cancer
Beesley, Vanessa L., Webber, Kate, Nagle, Christina M., DeFazio, Anna, Obermair, Andreas, Williams, Merran, Friedlander, Michael and Webb, Penelope M. (2020). When will I feel normal again? Trajectories and predictors of persistent symptoms and poor wellbeing after primary chemotherapy for ovarian cancer. Gynecologic Oncology, 159 (1), 179-186. doi: 10.1016/j.ygyno.2020.07.029
2020
Journal Article
Quality of life following minimally invasive hysterectomy compared to abdominal hysterectomy: a metanalysis
Bartels, Helena C., Rogers, Ailin C., Janda, Monika, Obermair, Andreas and Brennan, Donal J. (2020). Quality of life following minimally invasive hysterectomy compared to abdominal hysterectomy: a metanalysis. European Journal of Obstetrics and Gynecology and Reproductive Biology, 252, 206-212. doi: 10.1016/j.ejogrb.2020.06.055
Funding
Current funding
Past funding
Supervision
Availability
- Professor Andreas Obermair is:
- Available for supervision
Before you email them, read our advice on how to contact a supervisor.
Available projects
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feMMe: Uterus-preserving treatment of endometrial cancer
In 2020 we completed the feMMe, phase 2 cliniccal trial which established anticancer activity of levonorgestrel intrauterrine device (LNG-IUD) to treat endometrial cancer. The next two steps towards estabnlioshing this treatment for larger groups of patients include:
1. To determine factors that predict response to LNG-IUD
2. To determine long-term patient outcomes including survival, fertility, and patient needs.
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Improving Quality of Survival for Women with Gynaecological Cancer
- Focus on improving quality of life, health & function during & after gynaecological cancer treatment, with a focus on biomarker research, implementation research and cancer survivorship.
Supervision history
Current supervision
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Doctor Philosophy
Advanced methods for biomarker informed endometrial cancer
Principal Advisor
Other advisors: Dr Eva Baxter, Dr Zoe West, Professor Andrew Martin
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Master Philosophy
Patterns of care in endometrial cancer management in Queensland: a retrospective analysis.
Principal Advisor
Other advisors: Dr Eva Baxter
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Doctor Philosophy
Diet quality and composition in Australian women with endometrial cancer
Associate Advisor
Other advisors: Professor Monika Janda
Completed supervision
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2014
Doctor Philosophy
Hereditary endometrial cancer: Improving identification and referral of patients with suspected Lynch syndrome
Principal Advisor
Other advisors: Honorary Professor Amanda Spurdle, Associate Professor Lisa Fitzgerald
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2008
Doctor Philosophy
Nutritional status of patients with gynaecological cancer -
Joint Principal Advisor
Other advisors: Emeritus Professor Geoffrey Cleghorn
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Media
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