Associate Professor David Whiley
Associate Professor

David Whiley

Email: 
Phone: 
+61 7 334 65053

Availability

Associate Professor David Whiley is:
Available for supervision

Fields of research

Clinical sciences Medical microbiology

Qualifications

  • Bachelor of Applied Science, Queensland University of Technology
  • Bachelor of Law, Queensland University of Technology
  • Postgraduate Diploma, Queensland University of Technology
  • Doctor of Philosophy, The University of Queensland

Search Professor David Whiley’s works on UQ eSpace

337 works between 2001 and 2025
All (337) Journal Article (288) Book Chapter (12) Conference Publication (32) Other Outputs (5)

261 - 280 of 337 works

2011

Journal Article

False-negative results using Neisseria gonorrhoeae porA pseudogene PCR - a clinical gonococcal isolate with an N. meningitidis porA sequence, Australia, March 2011

Whiley, D.M., Limnios, A., Moon, N.J., Gehrig, N., Goire, N., Hogan, T., Lam, A., Jacob, K., Lambert, S.B., Nissen, M.D. and Sloots, T.P. (2011). False-negative results using Neisseria gonorrhoeae porA pseudogene PCR - a clinical gonococcal isolate with an N. meningitidis porA sequence, Australia, March 2011. Eurosurveillance, 16 (21), 5-8. doi: 10.2807/ese.16.21.19874-en

False-negative results using Neisseria gonorrhoeae porA pseudogene PCR - a clinical gonococcal isolate with an N. meningitidis porA sequence, Australia, March 2011

2011

Journal Article

Reduced susceptibility to ceftriaxone in Neisseria gonorrhoeae is spread internationally by genetically distinct gonococcal populations

Whiley, David M., Goire, Namraj, Lambert, Stephen B., Nissen, Michael D., Sloots, Theo P. and Tapsall, John W. (2011). Reduced susceptibility to ceftriaxone in Neisseria gonorrhoeae is spread internationally by genetically distinct gonococcal populations. Journal of Antimicrobial Chemotherapy, 66 (5) dkr052, 1186-1187. doi: 10.1093/jac/dkr052

Reduced susceptibility to ceftriaxone in Neisseria gonorrhoeae is spread internationally by genetically distinct gonococcal populations

2011

Journal Article

A real-time, quantitative PCR method using hydrolysis probes for the monitoring of Plasmodium falciparum load in experimentally infected human volunteers

Rockett, Rebecca J., Tozer, Sarah J., Peatey, Chris, Bialasiewicz, Seweryn, Whiley, David M., Nissen, Michael D., Trenholme, Katharine, Mc Carthy, James S. and Sloots, Theo P. (2011). A real-time, quantitative PCR method using hydrolysis probes for the monitoring of Plasmodium falciparum load in experimentally infected human volunteers. Malaria Journal, 10 (48) 48, 48-1-48-6. doi: 10.1186/1475-2875-10-48

A real-time, quantitative PCR method using hydrolysis probes for the monitoring of Plasmodium falciparum load in experimentally infected human volunteers

2011

Journal Article

Enhancing gonococcal antimicrobial resistance surveillance: a real-time PCR assay for detection of penicillinase-producing Neisseria gonorrhoeae by use of noncultured clinical samples

Goire, Namraj, Freeman, Kevin, Tapsall, John W., Lambert, Stephen B., Nissen, Michael D., Sloots, Theo P. and Whiley, David M. (2011). Enhancing gonococcal antimicrobial resistance surveillance: a real-time PCR assay for detection of penicillinase-producing Neisseria gonorrhoeae by use of noncultured clinical samples. Journal of clinical microbiology, 49 (2), 513-518. doi: 10.1128/JCM.02024-10

Enhancing gonococcal antimicrobial resistance surveillance: a real-time PCR assay for detection of penicillinase-producing Neisseria gonorrhoeae by use of noncultured clinical samples

2011

Book Chapter

Pseudomonas

Kidd, Timothy J., Whiley, David M., Bell, Scott C. and Grimwood, Keith (2011). Pseudomonas. Molecular detection of human bacterial pathogens. (pp. 1009-1021) edited by Dongyou Liu. Boca Raton, FL, USA: Taylor & Francis.

Pseudomonas

2010

Book Chapter

Sexually transmitted infections

Garland, Suzanne M., Smith, David W., Tabrizi, Sepehr N. and Whiley, David M. (2010). Sexually transmitted infections. PCR for Clinical Microbiology: An Australian and International Perspective. (pp. 99-115) Dordrecht: Springer Netherlands. doi: 10.1007/978-90-481-9039-3_8

Sexually transmitted infections

2010

Journal Article

Alterations of the pilQ gene in Neisseria gonorrhoeae are unlikely contributors to decreased susceptibility to ceftriaxone and cefixime in clinical gonococcal strains

Whiley, David M., Jacobsson, Susanne, Tapsall, John W., Nissen, Michael D., Sloots, Theo P. and Unemo, Magnus (2010). Alterations of the pilQ gene in Neisseria gonorrhoeae are unlikely contributors to decreased susceptibility to ceftriaxone and cefixime in clinical gonococcal strains. Journal of Antimicrobial Chemotherapy, 65 (12) dkq377, 2543-2547. doi: 10.1093/jac/dkq377

Alterations of the pilQ gene in Neisseria gonorrhoeae are unlikely contributors to decreased susceptibility to ceftriaxone and cefixime in clinical gonococcal strains

2010

Journal Article

Evaluation of the cobas 4800 CT/NG test for detecting Chlamydia trachomatis and Neisseria gonorrhoeae

Rockett, Rebecca, Goire, Namraj, Limnios, Athena, Turra, Mark, Higgens, Geoffrey, Lambert, Stephen B., Bletchly, Cheryl, Nissen, Michael D., Sloots, Theo P. and Whiley, David M. (2010). Evaluation of the cobas 4800 CT/NG test for detecting Chlamydia trachomatis and Neisseria gonorrhoeae. Sexually Transmitted Infections, 86 (6), 470-473. doi: 10.1136/sti.2010.042812

Evaluation of the cobas 4800 CT/NG test for detecting Chlamydia trachomatis and Neisseria gonorrhoeae

2010

Journal Article

Reduced susceptibility to ceftriaxone in neisseria gonorrhoeae is associated with mutations G542S, P551S and P551L in the gonococcal penicillin-binding protein 2

Whiley, David M., Goire, Namraj, Lambert, Stephen B., Ray, Sanghamitra, Limnios, E. Athena, Nissen, Michael D., Sloots, Theo P. and Tapsall, John W. (2010). Reduced susceptibility to ceftriaxone in neisseria gonorrhoeae is associated with mutations G542S, P551S and P551L in the gonococcal penicillin-binding protein 2. Journal of Antimicrobial Chemotherapy, 65 (8) dkq187, 1615-1618. doi: 10.1093/jac/dkq187

Reduced susceptibility to ceftriaxone in neisseria gonorrhoeae is associated with mutations G542S, P551S and P551L in the gonococcal penicillin-binding protein 2

2010

Journal Article

A simple approach for preparing real-time PCR positive reaction controls for rare or emerging viruses

Whiley, David M., Faux, Cassandra E., Bialasiewicz, Seweryn, Gould, Allan R., Lambert, Stephen B., Nissen, Michael D. and Sloots, Theo P. (2010). A simple approach for preparing real-time PCR positive reaction controls for rare or emerging viruses. Journal of Clinical Virology, 48 (3), 193-197. doi: 10.1016/j.jcv.2010.03.022

A simple approach for preparing real-time PCR positive reaction controls for rare or emerging viruses

2010

Journal Article

Whole-genome characterization and genotyping of global WU polyomavirus strains

Bialasiewicz, Seweryn, Rockett, Rebecca, Whiley, David W., Abed, Yacine, Allander, Tobias, Binks, Michael, Boivin, Guy, Cheng, Allen C., Chung, Ju-Young, Ferguson, Patricia E., Gilroy, Nicole M., Leach, Amanda J., Lindau, Cecilia, Rossen, John W., Sorrell, Tania C., Nissen, Michael D. and Sloots, Theo P. (2010). Whole-genome characterization and genotyping of global WU polyomavirus strains. Journal of Virology, 84 (12), 6229-6234. doi: 10.1128/JVI.02658-09

Whole-genome characterization and genotyping of global WU polyomavirus strains

2010

Book Chapter

Malaria (P. falciparum, P. vivax, P. malariae, P. ovale)

Bialasiewicz, Seweryn, Whiley, David M. and Sloots, Theo P. (2010). Malaria (P. falciparum, P. vivax, P. malariae, P. ovale). PCR for clinical microbiology : An Australian and international perspective. (pp. 373-377) edited by Margaret Schuller, Theo P. Sloots, Gregory S. James, Catriona L. Halliday and Ian W.J. Carter. Dordrecht ; London: Springer Publishing. doi: 10.1007/978-90-481-9039-3_64

Malaria (P. falciparum, P. vivax, P. malariae, P. ovale)

2010

Book Chapter

Respiratory infections

Nissen, Michael D., Lambert, Stephen B., Whiley, David M. and Sloots, Theo P. (2010). Respiratory infections. PCR for clinical microbiology: an Australian and international perspective. (pp. 67-82) edited by Margret Schuller, Theo P. Sloots, Gregory S. James, Catriona L. Halliday and Ian W. J. Carter. Dordrecht, Netherlands : Springer. doi: 10.1007/978-90-481-9039-3_5

Respiratory infections

2010

Book Chapter

Molecular amplification methods in diagnostic virology

Whiley, David M. and Sloots, Theo P. (2010). Molecular amplification methods in diagnostic virology. Lennette's laboratory diagnosis of viral infections. (pp. 19-39) edited by Keith R. Jerome. New York, United States; Boca Raton, FL, United States: Informa Healthcare; CRC Press.

Molecular amplification methods in diagnostic virology

2009

Journal Article

A novel duplex real-time reverse transcription PCR Assay for the detection of influenza A and the novel influenza A(H1N1)strain.

Rockett, Rebecca J., Bialasiewicz, Seweryn, Whiley, David M., Bletchly, Cheryl, Faux, Cassandra E., Lambert, Stephen B., Nimmo, Graeme R., Nissen, Michael D. and Sloots, Theodorus P. (2009). A novel duplex real-time reverse transcription PCR Assay for the detection of influenza A and the novel influenza A(H1N1)strain.. Viruses, 1 (3), 1204-1208. doi: 10.3390/v1031204

A novel duplex real-time reverse transcription PCR Assay for the detection of influenza A and the novel influenza A(H1N1)strain.

2009

Journal Article

An example of competitive inhibition in a monoplex real-time PCR as a cause of reduced fluorescent signal response

Goire, Namraj, Kattenbelt, Jacqueline A., Gould, Allan R., Nissen, Michael D., Sloots, Theo P. and Whiley, David (2009). An example of competitive inhibition in a monoplex real-time PCR as a cause of reduced fluorescent signal response. Pathology, 41 (6), 607-609. doi: 10.1080/00313020903071488

An example of competitive inhibition in a monoplex real-time PCR as a cause of reduced fluorescent signal response

2009

Journal Article

Simple, rapid, and inexpensive detection of Neisseria gonorrhoeae resistance mechanisms using heat-denatured isolates and SYBR green-based real-time PCR.

Kugelman, Gayle, Tapsall, John W., Goire, Namraj, Syrmis, Melanie, Limnios, Athena, Lambert, Stephen B., Nissen, Michael D., Sloots, Theo P. and Whiley, David M. (2009). Simple, rapid, and inexpensive detection of Neisseria gonorrhoeae resistance mechanisms using heat-denatured isolates and SYBR green-based real-time PCR.. Antimicrobial Agents & Chemotherapy, 53 (10), 4211-4216. doi: 10.1128/AAC.00385-09

Simple, rapid, and inexpensive detection of Neisseria gonorrhoeae resistance mechanisms using heat-denatured isolates and SYBR green-based real-time PCR.

2009

Journal Article

Neisseria gonorrhoeae multi-antigen sequence typing using non-cultured clinical specimens.

Whiley, David M., Goire, Namraj, Ray, E. Sanghamitra, Limnios, Althena, Lambert, Stephen B., Nissen, Michael D., Sloots, Theo P. and Tapsall, John W. (2009). Neisseria gonorrhoeae multi-antigen sequence typing using non-cultured clinical specimens.. Sexually Trasmitted Infections, 86 (1), 51-55. doi: 10.1136/sti.2009.037689

Neisseria gonorrhoeae multi-antigen sequence typing using non-cultured clinical specimens.

2009

Journal Article

Detection of BK, JC, WU, or KI polyomaviruses in faecal, urine, blood, cerebrospinal fluid and respiratory samples

Bialasiewicz, Seweryn, Whiley, David M., Lambert, Stephen B., Nissen, Michael D. and Sloots, Theo P. (2009). Detection of BK, JC, WU, or KI polyomaviruses in faecal, urine, blood, cerebrospinal fluid and respiratory samples. Journal of Clinical Virology, 45 (3), 249-254. doi: 10.1016/j.jcv.2009.05.002

Detection of BK, JC, WU, or KI polyomaviruses in faecal, urine, blood, cerebrospinal fluid and respiratory samples

2009

Journal Article

Detection of novel influenza A(H1N1) virus by real-time RT-PCR.

Whiley, David M., Bialasiewicz, Seweryn, Bletchly, Cheryl, Faux, Cassandra E., Harrower, Bruce, Gould, Allan R., Lambert, Stephen B., Nimmo, Graeme R., Nissen, Michael D. and Sloots, Theo P. (2009). Detection of novel influenza A(H1N1) virus by real-time RT-PCR.. Journal of Clinical Virology, 45 (3), 203-204. doi: 10.1016/j.jcv.2009.05.032

Detection of novel influenza A(H1N1) virus by real-time RT-PCR.

Current funding

  • 2024 - 2026
    Rapid detection of Neisseria gonorrhoeae and relevant antimicrobial resistance targets
    Bill & Melinda Gates Foundation
    Open grant
  • 2024 - 2025
    A Rapid, Routine Genomics Service for Clinical Haematology (QLD Health Targeted CRF led by RBWH Metro North Health)
    Metro North Hospital and Health Service
    Open grant
  • 2023 - 2027
    Accelerating pathogen detection and antibiotic resistance prediction in children with suspected sepsis
    The Children's Hospital Foundation
    Open grant
  • 2022 - 2025
    Tackling the rise: Expanded gonorrhoea screening to inform guidelines for asymptomatic heterosexual women and men
    Australasian Society for HIV, Viral Hepatitis and Sexual Health Medicine
    Open grant
  • 2022 - 2026
    Can mass drug administration reduce the incidence of adverse perinatal outcomes and other health consequences of endemic sexually transmitted infections? A community effectiveness (UNSW NHMRC CTCS)
    University of New South Wales
    Open grant
  • 2022 - 2027
    Scaling up infectious disease point-of-care testing for Indigenous people (MRFF Rapid Applied Research Translation Grant administered by UNSW)
    University of New South Wales
    Open grant
  • 2021 - 2026
    ARC Research Hub to Combat Antimicrobial Resistance (ITRH led by University of New South Wales)
    University of New South Wales
    Open grant
  • 2021 - 2025
    META-GP: Delivering a Clinical Metagenomics Platform for Australia (administered by University of Melbourne)
    University of Melbourne
    Open grant
  • 2020 - 2025
    Eliminating endemic sexually transmissible infections in remote Australia using targeted multidisciplinary strategies
    NHMRC Synergy Grants
    Open grant

Past funding

  • 2022
    ResistancePlus MABSC/MAC test for detection of MABSC, MAC and gene markers associated with susceptibility or resistance to macrolides and amikacin antibiotics
    SpeedX
    Open grant
  • 2021 - 2022
    Improving Diagnosis, Management and Prevention of Invasive Meningococcal Disease
    Metro North Hospital and Health Service
    Open grant
  • 2020 - 2023
    The development of an integrated molecular diagnostic pathway to optimise the treatment of cytomegalovirus in children undergoing haematopoietic stem cell transplant
    The Children's Hospital Foundation
    Open grant
  • 2020 - 2024
    Precision public health and precision medicine for enhanced management sexually transmitted infections in Queensland
    Queensland Advancing Clinical Research Fellowship
    Open grant
  • 2020
    Refining a method for Effective Pooling of Anatomical Specimens for the Detection of STI RAPID GeneXpert CT/NG Pooling Trial
    Cepheid
    Open grant
  • 2020 - 2024
    A multicentre randomised controlled trial evaluating the efficacy of the meningococcal B vaccine, 4CMenB (Bexsero), against Neisseria gonorrhoeae... (NHMRC CTCS administered by Griffith University)
    Griffith University
    Open grant
  • 2019 - 2024
    Gono B Gone: Targeted immunisation programs for vulnerable children and young people against serious infectious diseases (NHMRC Partnership Project administered by University of Adelaide)
    University of Adelaide
    Open grant
  • 2019 - 2022
    Precision public health for enhanced syphilis management in Queensland
    Australasian Society for HIV, Viral Hepatitis and Sexual Health Medicine
    Open grant
  • 2019 - 2021
    Optimizing antimicrobial therapy for urinary tract infections in children via rapid direct next generation sequencing
    Pathology Queensland - Study, Education & Research Trust Fund
    Open grant
  • 2019 - 2021
    Virulence and detection of Escherichia coli that cause neonatal meningitis
    The Children's Hospital Foundation
    Open grant
  • 2018 - 2025
    Centre for Research Excellence in the accelerated implementation of new point-of-care technology for infectious diseases (NHMRC CRE Grant administered by the University of New South Wales)
    University of New South Wales
    Open grant
  • 2018 - 2020
    Enhanced diagnostic testing for Mycoplasma genitalium antibiotic resistance
    Pathology Queensland - Study, Education & Research Trust Fund
    Open grant
  • 2018 - 2019
    Sakzewski Core Translational Research Group
    The Children's Hospital Foundation
    Open grant
  • 2018 - 2021
    Enhancing detection and management of Mycobacterium abscessus complex (MABSC) infection in children with cystic fibrosis
    The Children's Hospital Foundation
    Open grant
  • 2018
    Individualised treatment of bacterial infections via rapid molecular detection of antibiotic resistant superbugs
    UQ Major Equipment and Infrastructure
    Open grant
  • 2018 - 2021
    Modelling the impact of strategies to control gonorrhoea and minimise the threat of antimicrobial resistance in remote Indigenous and (NHMRC Project Grant led by the University of New South Wales)
    University of New South Wales
    Open grant
  • 2017 - 2019
    An enhanced diagnostic test for Rotavirus infection
    Pathology Queensland - Study, Education & Research Trust Fund
    Open grant
  • 2017 - 2019
    A randomised controlled trial of daily antibacterial mouthwash to reduce pharyngeal gonorrhoea among men who have sex with men (MSM) (NHMRC Project Grant led by Monash University)
    Monash University
    Open grant
  • 2017 - 2021
    Use of molecular resistance assays to provide alterative oral treatment strategies for gonorrhoea in Indigenous and other high-risk populations; a randomised cluster trial
    NHMRC Project Grant
    Open grant
  • 2016 - 2017
    Typing isolates of Neisseria gonorrhoea
    Cempra Pharmaceuticals, Inc.
    Open grant
  • 2016 - 2020
    Resistance PCR collaborative project
    SpeedX
    Open grant
  • 2016 - 2019
    Gonorrhoea: detection, antimicrobial resistance and treatment.
    NHMRC Career Development Fellowship
    Open grant
  • 2015
    Combating the new antimicrobial resistance threat: development and implementation of cost-effective molecular surveillance tools
    Pathology Queensland - Study, Education & Research Trust Fund
    Open grant
  • 2015 - 2016
    New molecular tools to identify groups of individuals at increased risk of human immunodeficiency virus (HIV) acquisition
    HIVFQ HIV Research Grants
    Open grant
  • 2014 - 2015
    Ending trachoma: chasing Chlamydia trachomatis in eyes and from Australia
    Queensland University of Technology
    Open grant
  • 2014 - 2016
    Intra-strain diversity of Pseudomonas aeruginosa in the lungs of patients with CF and their role in exacerbation
    Prince Charles Hospital Foundation
    Open grant
  • 2014 - 2018
    New ways to increase the number of people in remote Aboriginal communities tested for sexually transmitted infections (NHMRC Project Grant administered by UNSW)
    University of New South Wales
    Open grant
  • 2013 - 2015
    NHMRC ECF (Health Prof RF (PT) - Public Health): Acquisition and transmission of respiratory pathogens in persons with cystic fibrosis (CF): development and implementation of novel molecular tools
    NHMRC Training (Postdoctoral) Fellowship
    Open grant
  • 2012 - 2015
    Molecular surveillance methods for Neisseria gonorrhoeae antimicrobial resistance
    Royal Children's Hospital Foundation
    Open grant
  • 2012 - 2015
    Neisseria gonorrhoeae antimicrobial resistance: detection and propagation
    NHMRC Project Grant
    Open grant
  • 2011 - 2014
    A randomised trial of rapid point-of-care tests for chlamydia and gonorrhoea infections in remote Aboriginal communities (NHMRC Project Grant administered by UNSW)
    University of New South Wales
    Open grant
  • 2011
    Metagenomic analysis of bronchoalveolar lavage fluid from children with cystic fibrosis and disease controls
    Royal Children's Hospital Foundation
    Open grant
  • 2011 - 2014
    The genetic properties of clonal Pseudomonas Aeruginosa strains in Brisbane patients with CF
    Royal Children's Hospital Foundation
    Open grant
  • 2010 - 2011
    Development of a novel assay for the detection of clonal P.aeruginosa in persons with CF
    Australian Cystic Fibrosis Research Trust
    Open grant
  • 2010 - 2014
    Burden of respiratory infection in the first 2 years of life: a birth cohort study of emerging respiratory pathogens
    NHMRC Project Grant
    Open grant
  • 2009 - 2011
    Identification of unknown viruses causing respiratory disease in children
    Royal Children's Hospital Foundation
    Open grant

Availability

Associate Professor David Whiley is:
Available for supervision

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Supervision history

Current supervision

  • Doctor Philosophy

    Rapid detection of AMR targets using isothermal technology

    Principal Advisor

    Other advisors: Associate Professor Adam Irwin

  • Doctor Philosophy

    Design and evaluation of point-of-care molecular diagnostics and metagenomics for tropical aetiological surveillence.

    Principal Advisor

  • Doctor Philosophy

    Design and evaluation of point-of-care molecular diagnostics and metagenomics for tropical aetiological surveillence.

    Principal Advisor

  • Doctor Philosophy

    New treatment strategies for STIs: Development of a molecular diagnostic test for cefixime-resistant gonorrhoea

    Principal Advisor

    Other advisors: Dr Emma Sweeney

  • Doctor Philosophy

    Design and evaluation of point-of-care molecular diagnostics and metagenomics for tropical aetiological surveillence.

    Principal Advisor

  • Doctor Philosophy

    The epidemiology of gonorrhoea in Queensland

    Principal Advisor

    Other advisors: Associate Professor Steve Lambert

  • Doctor Philosophy

    Rapid detection of AMR targets using isothermal technology.

    Principal Advisor

    Other advisors: Associate Professor Adam Irwin, Dr Leah Roberts

  • Doctor Philosophy

    Rapid detection of AMR targets using isothermal technology

    Principal Advisor

    Other advisors: Associate Professor Adam Irwin

  • Doctor Philosophy

    Accelerating pathogen detection and antibiotic resistance prediction in children with suspected sepsis.

    Associate Advisor

    Other advisors: Dr Patrick Harris, Associate Professor Adam Irwin

  • Doctor Philosophy

    The development of an integrated molecular diagnostic pathway to optimise the treatment of cytomegalovirus in children undergoing haematopoietic stem cell transplant

    Associate Advisor

    Other advisors: Dr Kym Lowry, Associate Professor Adam Irwin, Dr Emma Sweeney

  • Doctor Philosophy

    The development of an integrated molecular diagnostic pathway to optimise the treatment of cytomegalovirus in children undergoing haematopoietic stem cell transplant

    Associate Advisor

    Other advisors: Dr Kym Lowry, Associate Professor Adam Irwin, Dr Emma Sweeney

Completed supervision

Enquiries

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