
Overview
Background
I lead the Technology-Driven Drug Discovery (Tech3D) Group at the Institute for Molecular Bioscience, UQ. We believe that the key to solving some of our world's biggest challenges, whether that be in medicine or agriculture, relies on the ability to precision engineer molecules at will. My group harnesses three technological pillars to engineer peptides and proteins, which are computational biology, molecular libraries, and nanotechnology. We aspire to design better drugs, creating next generation biotechnological agents that have real impact. These could be new cancer drugs that harness the body's immune system or new insecticides that are environmentally friendly. In these pursuits, we value advancement, fun, balance, respect, fairness, and integrity.
I have been involved in peptide and protein research for over two decades, and am highly experienced in bioinformatics, chemistry, structural characterization, biophysics, and biochemistry. I trained with experts in peptide and protein characterization: an Honours project with Professor Garry King at the University of New South Wales, Sydney, Australia (2004), an APA scholarship with Professor David Craik at the University of Queensland Institute for Molecular Bioscience, Brisbane, Australia (2005-2009) and a NHMRC fellowship with Professor Mingjie Zhang at the Hong Kong University of Science and Technology, Hong Kong, China (2009-2011) and A/Professor Andreas Hofmann at Griffith University Eskitis Institute, Brisbane, Australia (2011-2012). I returned to the University of Queensland in 2012 to join an industry partnership funded by an ARC linkage grant. I currently hold an ARC Future Fellowship and am responsible for a team of research officers, assistants and postgraduate students.
My research output has been recognised by >30 prizes and awards for leadership, research translation and fundamental research excellence, as well as numerous invitations to speak at academic and pharmaceutical conferences. I have over 100 publications and have been cited by researchers from across the world.
Availability
- Dr Conan Wang is:
- Available for supervision
Qualifications
- Bachelor of Engineering, University of New South Wales
- Doctor of Philosophy, The University of Queensland
Research interests
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Drug Discovery and Protein/Peptide Engineeering
My group uses: 1) computational algorithms to predict drug properties with unprecedented accuracy; 2) molecular libraries capable of screening through billions of drug leads to design drugs efficiently; and 3) nano-sized reaction droplets to capture drug activity to make drugs that actually work.
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Cancer Therapeutics
My group is interested in developing new cancer therapeutics, particularly those that modulate the immune system or relevant to lung cancer.
Works
Search Professor Conan Wang’s works on UQ eSpace
2006
Journal Article
The cyclotide family of circular miniproteins: Nature's combinatorial peptide template
Craik, D. J., Cemazar, M., Wang, C. K. L. and Daly, N. L. (2006). The cyclotide family of circular miniproteins: Nature's combinatorial peptide template. Biopolymers, 84 (3), 250-266. doi: 10.1002/hip.20451
Funding
Current funding
Past funding
Supervision
Availability
- Dr Conan Wang is:
- Available for supervision
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Available projects
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Molecular design of drugs for cancer diagnosis, imaging and therapy.
In this industry-linked project, an exceptional opportunity awaits a highly motivated PhD candidate interested in discovery and engineering of peptide drugs to combat cancer.
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Molecular design of drugs for cancer diagnosis, imaging and therapy.
In this industry-linked project, an exceptional opportunity awaits a highly motivated PhD candidate interested in discovery and engineering of peptide drugs to combat cancer.
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Design of novel cancer therapeutics to combat drug resistance
Develop a suite of technologies to overcome key challenges in cancer drug resistance.
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PhD top-up scholarship: Design and manufacturing of next-generation ultra-stable peptide radiotracers for precision diagnosis and therapy
Scholarship + Top-up opportunity for a talented domestic student.
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PhD top-up scholarship: Technology-driven discovery of sustainable next-generation insecticides
Scholarship + Top-up opportunity for a talented international/domestic student interesting in designing novel ecofriendly insecticides for safeguarding agriculture.
Supervision history
Current supervision
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Doctor Philosophy
A new molecular technology platform for design and production of ultra-stable peptides
Principal Advisor
Other advisors: Professor David Craik
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Doctor Philosophy
Patient-friendly peptide tracers for improving immunotherapy outcomes
Principal Advisor
Other advisors: Dr Yen-Hua Crystal Huang
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Doctor Philosophy
Discovery and Development of Substrate-Based Peptide Kinase Inhibitors
Principal Advisor
Other advisors: Dr Yen-Hua Crystal Huang, Professor David Craik
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Doctor Philosophy
Next-generation IL-2 mimics for immunotherapy
Principal Advisor
Other advisors: Professor David Craik, Professor Di Yu
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Doctor Philosophy
Development of commercially viable cyclic peptide production for the protection of the Great Barrier Reef
Associate Advisor
Other advisors: Professor David Craik, Dr Thomas Durek, Professor Linda Lua
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Doctor Philosophy
Exploring delivery strategies for cyclotide-based therapeutics
Associate Advisor
Other advisors: Dr Yen-Hua Crystal Huang, Professor David Craik
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Doctor Philosophy
Development of peptide-based inhibitors for crop protection
Associate Advisor
Other advisors: Professor Brett Collins, Professor David Craik
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Doctor Philosophy
Development of a new class of ligase enzymes for protein engineering and drug development
Associate Advisor
Other advisors: Professor David Craik, Dr Thomas Durek
Completed supervision
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2021
Doctor Philosophy
The development of peptide-based cholesterol-lowering therapeutics
Principal Advisor
Other advisors: Professor David Craik
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2024
Doctor Philosophy
Discovery, production, and development of disulfide-rich peptides for drug design and development
Associate Advisor
Other advisors: Professor David Craik, Dr Thomas Durek
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2023
Doctor Philosophy
Structural Modifications to Optimise the Oxidative Folding and Activity of Cyclotides
Associate Advisor
Other advisors: Dr Simon de Veer, Professor David Craik
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2023
Doctor Philosophy
Characterising the crown-of-thorns starfish secretome to identify factors for future biocontrol systems
Associate Advisor
Other advisors: Professor Sandie Degnan, Professor Bernard Degnan
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2022
Doctor Philosophy
Investigating approaches for the design and delivery of disulfide-rich peptide therapeutics
Associate Advisor
Other advisors: Dr Yen-Hua Crystal Huang, Professor David Craik
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2015
Doctor Philosophy
Structure-activity relationships and development of disulfide-rich cyclic peptides as pharmaceutical templates
Associate Advisor
Other advisors: Professor David Craik
Media
Enquiries
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