Professor Karen Moritz
Professor

Karen Moritz

Email: 
Phone: 
+61 7 334 65305

Background

Prof Karen Moritz is internationally renowned for her work in understanding how early life perturbations contribute to an increased risk of developing cardiovascular, renal and metabolic disease in adulthood. Over the last 5-7 years, her research has focused on determining how prenatal alcohol can result in “developmental programming” of disease. Her research has identified critical windows of susceptibility to alcohol, including the period around conception and prior to implantation. In addition, her work has identified the placenta as playing a key role in the sex-specific offspring outcomes following maternal perturbations. Her research spans both preclinical and clinical domains, highlighted by her appointment as the Director of the Child Health Research Centre in 2016.

Current projects are:

  • Periconceptional alcohol exposure: Programming long-term health in offspring (with Dr Lisa Akison and Dr James Cuffe)

  • Emerging therapies for diabetes and complications: Effects on metabolic, cardiovascular and renal function (with Dr Linda Gallo)

  • Effect of prenatal insults on the developing placenta (with Dr Marloes Nitert Dekker, Prof Vicki Clifton [Mater], Dr David Simmons and Dr James Cuffe)

  • Effect of prenatal insults on the developing kidney and implications for adult disease (with Dr Peter Trnka [QLD Children's Hospital])

  • Impact of maternal cannabis and alcohol around conception on development and long-term health of offspring (with Dr David Simmons and Dr Lisa Akison)

Prof Moritz maintains a strong commitment to teaching of students, including lectures and research student supervision in undergraduate programs, supervision of Honours students and supervision of higher degree research students.

Availability

Professor Karen Moritz is:
Available for supervision

Fields of research

Clinical sciences Zoology

Qualifications

  • Doctor of Philosophy, University of Melbourne

Search Professor Karen Moritz’s works on UQ eSpace

365 works between 1990 and 2025
All (365) Journal Article (254) Book Chapter (5) Conference Publication (99) Book (1) Other Outputs (6)

341 - 360 of 365 works

1998

Journal Article

The renin-angiotensin system and the development of the kidney and adrenal in sheep

Wintour, EM, Alcorn, D, Albiston, A, Boon, WC, Butkus, A, Earnest, L, Moritz, K and Shandley, L (1998). The renin-angiotensin system and the development of the kidney and adrenal in sheep. Clinical and Experimental Pharmacology and Physiology, 25, S97-S100. doi: 10.1111/j.1440-1681.1998.tb02309.x

The renin-angiotensin system and the development of the kidney and adrenal in sheep

1998

Journal Article

Regulation and function of steroid production by mid gestation ovine fetal adrenal cortex in vivo.

Moritz, KM, Butkus, A, McFarlane, AC, Albiston, A, Salenmi, R and Wintour, EM (1998). Regulation and function of steroid production by mid gestation ovine fetal adrenal cortex in vivo.. Endocrine Research, 24 (3-4), 937-941.

Regulation and function of steroid production by mid gestation ovine fetal adrenal cortex in vivo.

1997

Journal Article

Developmental regulation of erythropoietin and erythropoiesis

Moritz, KM, Lim, GB and Wintour, EM (1997). Developmental regulation of erythropoietin and erythropoiesis. American Journal of Physiology-Regulatory Integrative and Comparative Physiology, 273 (6), R1829-R1844.

Developmental regulation of erythropoietin and erythropoiesis

1997

Journal Article

Ontogeny of angiotensin II receptors, types 1 and 2, in ovine mesonephros and metanephros

Butkus, A, Albiston, A, Alcorn, D, Giles, M, McCausland, J, Moritz, K, Zhuo, JL and Wintour, EM (1997). Ontogeny of angiotensin II receptors, types 1 and 2, in ovine mesonephros and metanephros. Kidney International, 52 (3), 628-636. doi: 10.1038/ki.1997.376

Ontogeny of angiotensin II receptors, types 1 and 2, in ovine mesonephros and metanephros

1997

Conference Publication

Expression of aquaporin-1 (AQP1) in the adult and developing sheep kidney

Butkus, A, Alcorn, D, Earnest, L, Moritz, K, Giles, M and Wintour, EM (1997). Expression of aquaporin-1 (AQP1) in the adult and developing sheep kidney. doi: 10.1016/S0248-4900(97)83384-9

Expression of aquaporin-1 (AQP1) in the adult and developing sheep kidney

1997

Journal Article

Renal, hormonal, and cardiovascular responses to chronic angiotensin I infusion in the ovine fetus

Moritz, KM, Tangalakis, K and Wintour, EM (1997). Renal, hormonal, and cardiovascular responses to chronic angiotensin I infusion in the ovine fetus. American Journal of Physiology-Regulatory Integrative and Comparative Physiology, 272 (6), R1912-R1917. doi: 10.1152/ajpregu.1997.272.6.R1912

Renal, hormonal, and cardiovascular responses to chronic angiotensin I infusion in the ovine fetus

1997

Journal Article

Collagen in the fetal membranes of sheep: changes throughout gestation and effects of dexamethasone at 60 days

Shandley, L, Moritz, KM, Samuel, CS and Wintour, EM (1997). Collagen in the fetal membranes of sheep: changes throughout gestation and effects of dexamethasone at 60 days. Reproduction Fertility and Development, 9 (4), 455-464. doi: 10.1071/R96103

Collagen in the fetal membranes of sheep: changes throughout gestation and effects of dexamethasone at 60 days

1996

Journal Article

Experimental hydranencephaly in the ovine fetus

Wintour, EM, Lewitt, M, McFarlane, A, Moritz, K, Potocnik, S, Rees, S and Tangalakis, K (1996). Experimental hydranencephaly in the ovine fetus. Acta Neuropathologica, 91 (5), 537-544. doi: 10.1007/s004010050463

Experimental hydranencephaly in the ovine fetus

1996

Journal Article

Effect of hemorrhage and nephrectomy on erythropoietin gene expression in the ovine fetus

Lim, GB, Moritz, K, Jeyaseelan, K and Wintour, EM (1996). Effect of hemorrhage and nephrectomy on erythropoietin gene expression in the ovine fetus. Molecular and Cellular Endocrinology, 117 (1), 101-109. doi: 10.1016/0303-7207(95)03736-5

Effect of hemorrhage and nephrectomy on erythropoietin gene expression in the ovine fetus

1996

Journal Article

Changes in blood and red cell volume in the neonatal lamb and the effect of insulin-like growth factor I

Moritz, KM, Owens, PC and Wintour, EM (1996). Changes in blood and red cell volume in the neonatal lamb and the effect of insulin-like growth factor I. Clinical and Experimental Pharmacology and Physiology, 23 (2), 134-139. doi: 10.1111/j.1440-1681.1996.tb02584.x

Changes in blood and red cell volume in the neonatal lamb and the effect of insulin-like growth factor I

1995

Journal Article

Cardiovascular, Hormonal, and Metabolic Responses to Severe Prolonged Hemorrhage in Adult Sheep

Wintour, EM, Moritz, KM and Potocnik, SJ (1995). Cardiovascular, Hormonal, and Metabolic Responses to Severe Prolonged Hemorrhage in Adult Sheep. American Journal of Veterinary Research, 56 (9), 1232-1240.

Cardiovascular, Hormonal, and Metabolic Responses to Severe Prolonged Hemorrhage in Adult Sheep

1995

Journal Article

Pituitary-Adrenal-Function in the Immature Ovine Fetus

McFarlane, AC, Potocnik, S, Towstoless, M, Moritz, K and Wintour, EM (1995). Pituitary-Adrenal-Function in the Immature Ovine Fetus. Journal of Endocrinology, 145 (3), 455-460. doi: 10.1677/joe.0.1450455

Pituitary-Adrenal-Function in the Immature Ovine Fetus

1995

Journal Article

Erythropoietin Gene-Expression in Fetal and Adult Sheep Kidney

Darby, IA, Evans, BA, Fu, P, Lim, GB, Moritz, KM and Wintour, EM (1995). Erythropoietin Gene-Expression in Fetal and Adult Sheep Kidney. British Journal of Haematology, 89 (2), 266-270. doi: 10.1111/j.1365-2141.1995.tb03299.x

Erythropoietin Gene-Expression in Fetal and Adult Sheep Kidney

1995

Conference Publication

Effect of maternal glucocorticoid treatment on ovine fetal fluids at 0.6 gestation

Tangalakis, K, Moritz, K, Shandley, L and Wintour, EM (1995). Effect of maternal glucocorticoid treatment on ovine fetal fluids at 0.6 gestation. 1st International Meeting of World Placenta Associations, Sydney Australia, Oct 24-28, 1994. COLLINGWOOD: C S I R O PUBLICATIONS. doi: 10.1071/RD9951595

Effect of maternal glucocorticoid treatment on ovine fetal fluids at 0.6 gestation

1995

Journal Article

Regulation and Function of the Fetal Adrenal-Gland in Sheep

Wintour, EM, Crawford, R, McFarlane, A, Moritz, K and Tangalakis, K (1995). Regulation and Function of the Fetal Adrenal-Gland in Sheep. Endocrine Research, 21 (1-2), 81-89.

Regulation and Function of the Fetal Adrenal-Gland in Sheep

1994

Journal Article

Effect of Maternal Glucocorticoid Treatment On Fetal Fluids in Sheep At 0.4 Gestation

Wintour, EM, Alcorn, D, McFarlane, A, Moritz, K, Potocnik, SJ and Tangalakis, K (1994). Effect of Maternal Glucocorticoid Treatment On Fetal Fluids in Sheep At 0.4 Gestation. American Journal of Physiology, 266 (4), R1174-R1181. doi: 10.1152/ajpregu.1994.266.4.R1174

Effect of Maternal Glucocorticoid Treatment On Fetal Fluids in Sheep At 0.4 Gestation

1994

Journal Article

BLOOD VOLUME MEASUREMENTS IN THE NEONATAL LAMB: VALIDATION OF A METHOD USING [51Cr]‐LABELLED RED CELLS

Moritz, KM, Potocnik, SJ, Tangalakis, K and Wintour, EM (1994). BLOOD VOLUME MEASUREMENTS IN THE NEONATAL LAMB: VALIDATION OF A METHOD USING [51Cr]‐LABELLED RED CELLS. Clinical and Experimental Pharmacology and Physiology, 21 (7), 577-581. doi: 10.1111/j.1440-1681.1994.tb02557.x

BLOOD VOLUME MEASUREMENTS IN THE NEONATAL LAMB: VALIDATION OF A METHOD USING [51Cr]‐LABELLED RED CELLS

1993

Journal Article

EFFECT OF ARGININE VASOPRESSIN AND PARATHYROID HORMONE‐RELATED PROTEIN ON RENAL FUNCTION IN THE OVINE FOETUS

Horne, Rsc, Macisaac, RJ, Moritz, KM, Tangalakis, K and Wintour, EM (1993). EFFECT OF ARGININE VASOPRESSIN AND PARATHYROID HORMONE‐RELATED PROTEIN ON RENAL FUNCTION IN THE OVINE FOETUS. Clinical and Experimental Pharmacology and Physiology, 20 (9), 569-577. doi: 10.1111/j.1440-1681.1993.tb01743.x

EFFECT OF ARGININE VASOPRESSIN AND PARATHYROID HORMONE‐RELATED PROTEIN ON RENAL FUNCTION IN THE OVINE FOETUS

1993

Journal Article

The sheep erythropoietin gene: molecular cloning and effect of hemorrhage on plasma erythropoietin and renal/liver messenger RNA in adult sheep

Fu, P, Evans, B, Lim, GB, Moritz, K and Wintour, EM (1993). The sheep erythropoietin gene: molecular cloning and effect of hemorrhage on plasma erythropoietin and renal/liver messenger RNA in adult sheep. Molecular and Cellular Endocrinology, 93 (2), 107-116. doi: 10.1016/0303-7207(93)90113-X

The sheep erythropoietin gene: molecular cloning and effect of hemorrhage on plasma erythropoietin and renal/liver messenger RNA in adult sheep

1992

Journal Article

Effect of Cortisol On Blood-Pressure and Vascular Reactivity in the Ovine Fetus

Tangalakis, K, Lumbers, ER, Moritz, KM, Towstoless, MK and Wintour, EM (1992). Effect of Cortisol On Blood-Pressure and Vascular Reactivity in the Ovine Fetus. Experimental Physiology, 77 (5), 709-717. doi: 10.1113/expphysiol.1992.sp003637

Effect of Cortisol On Blood-Pressure and Vascular Reactivity in the Ovine Fetus

Current funding

  • 2024 - 2027
    Understanding how binge drinking affects kidney development (NHMRC 2023 Ideas Grant administed by Monash)
    Monash University
    Open grant
  • 2022 - 2025
    Expansion of FASD Diagnostic Services in Southern Queensland with Support for regional and remote settings
    Drug and Alcohol Program
    Open grant
  • 2020 - 2025
    A tiered approach to the diagnosis of Fetal Alcohol Spectrum Disorder (FASD) in remote Indigenous primary care settings (NHMRC Partnership Project administered by Griffith University)
    Griffith University
    Open grant
  • 2020 - 2025
    Gene Expression to Predict Long-Term Outcome in Infants After Heart Surgery
    MRFF Accelerated Research - Congenital Heart Disease administered by AusIndustry
    Open grant
  • 2020 - 2025
    Host Gene Expression Signatures to Diagnose Sepsis in Children
    MRFF Genomics Health Futures Mission, Project Grant administered by AusIndustry
    Open grant

Past funding

  • 2020 - 2024
    The Drug and Alcohol Program: Review and Dissemination of the Australian Fetal Alcohol Spectrum Disorder (FASD) Diagnostic Tool GO2647
    Commonwealth Department of Health
    Open grant
  • 2019
    Vevo 3100 Imaging System for ultrahigh resolution and frame rate echocardiographic assessment of small animals.
    UQ Major Equipment and Infrastructure
    Open grant
  • 2018 - 2019
    The Best I can Be: Screening and assessing for FASD in the foster care system
    Key Assets the Children's Services Provider (Australia) Limited
    Open grant
  • 2018 - 2019
    Sakzewski Core Translational Research Group
    The Children's Hospital Foundation
    Open grant
  • 2018
    Chronic health outcomes following early life exposure to alcohol
    Queensland Health
    Open grant
  • 2018 - 2020
    Foetal Alcohol Spectrum Disorder (FASD) Diagnostic Services and Models of Care (Led by Griffith University)
    Griffith University
    Open grant
  • 2017 - 2018
    Sakzewski Core Translational Research Group
    The Children's Hospital Foundation
    Open grant
  • 2015
    A state-of-the-art spinning disc confocal microscope for high speed imaging of live cells and super resolution microscopy
    UQ Major Equipment and Infrastructure
    Open grant
  • 2015 - 2020
    NHMRC Research Fellowship: Developmental programming: mechanisms and interventions
    NHMRC Research Fellowship
    Open grant
  • 2014
    Mitochondrial analysis suite
    UQ Major Equipment and Infrastructure
    Open grant
  • 2013
    Establishment of an Integrated Facility for Single Cell Analysis
    UQ Major Equipment and Infrastructure
    Open grant
  • 2013 - 2015
    Mechanisms and consequences of renal denervation in chronic kidney disease (NHMRC Project Grant administered by Baker IDI Heart and Diabetes Institute)
    Baker IDI Heart & Diabetes Institute
    Open grant
  • 2013 - 2015
    Periconceptional alcohol exposure: effects on the embryo and fetus and disease risk in adulthood
    NHMRC Project Grant
    Open grant
  • 2012 - 2014
    Consequences of elevated maternal glucocorticoids for early childhood renal development and function (NHMRC Project administered by Monash University)
    Monash University
    Open grant
  • 2012
    Establishment of Integrated Small Animal Metabolic and Physiology Assessment Facility
    UQ Major Equipment and Infrastructure
    Open grant
  • 2012
    Examining vascular structure and function using pressurised myography
    NHMRC Equipment Grant
    Open grant
  • 2012
    Placental clock gene expression in the Spiny Mouse
    UWA-UQ Bilateral Research Collaboration Award
    Open grant
  • 2012 - 2014
    Stress-induced disease risk for pregnant mothers born small (NHMRC project lead by University of Melbourne)
    University of Melbourne
    Open grant
  • 2011 - 2013
    Modelling the regulation of nephron number by the renal stem cell niche
    NHMRC Project Grant
    Open grant
  • 2011
    Real time regional tissue analysis suite
    UQ Major Equipment and Infrastructure
    Open grant
  • 2011 - 2013
    ResTeach 2011 0.2 FTE School of Biomedical Sciences
    UQ ResTeach
    Open grant
  • 2011 - 2013
    The role of hypoxia in the developmental programming of the kidney
    NHMRC Project Grant
    Open grant
  • 2010
    Establishment of a digital Scanscope system for virtual microscopy
    UQ Major Equipment and Infrastructure
    Open grant
  • 2010
    In Situ Hybridization Suite for Biomedical Science Researchers
    NHMRC Equipment Grant
    Open grant
  • 2010 - 2014
    NHMRC Research Fellowship
    NHMRC Research Fellowship
    Open grant
  • 2009 - 2010
    How do prenatal perturbations influence kidney development and result in adult onset diseases
    UQ Foundation Research Excellence Awards - DVC(R) Funding
    Open grant
  • 2009
    "Real Time PCR Facility for Biomedical Researchers"
    UQ School/Centre Co-Funding
    Open grant
  • 2009 - 2010
    Does moderate prenatal alcohol exposure cause metabolic disease
    Diabetes Australia Research Trust
    Open grant
  • 2009 - 2010
    Poor kidney development resulting in kidney disease and high blood pressure
    National Heart Foundation of Australia
    Open grant
  • 2009
    Quantitative Histological Core Facility
    UQ School/Centre Co-Funding
    Open grant

Availability

Professor Karen Moritz is:
Available for supervision

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Supervision history

Current supervision

  • Master Philosophy

    Biomarkers of acute kidney injury in infants

    Principal Advisor

  • Doctor Philosophy

    Delphi Study of Pregnancy Alcohol Risk Perceptions: Application for Health Educational Resources

    Associate Advisor

    Other advisors: Dr Natasha Reid

  • Doctor Philosophy

    Advancing facial dysmorphology diagnostic practices for fetal alcohol spectrum disorder

    Associate Advisor

    Other advisors: Dr Lisa Akison, Dr Natasha Reid

Completed supervision

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