Overview
Background
Professor Rachel Allavena is a specialist veterinary pathologist, multidisciplinary researcher and Deputy Head of School, at the School of Veterinary Science, Gatton. She develops cancer treatments called immunotherapies which wake up the immune system so it fights the cancer. Her unique approach uses pet dogs with natural cancer to conduct the research. This helps the dog and it's family, as well as progressing the development of veterinary treatments and simultaneously advancing human medicine. As Deputy Head of School she aims to support staff and students to make UQ one of the top school's in Australasia, supporting both pets and people. Rachel is a multi-award winning teacher, lecturinging in veterinary pathology, toxicology, animal welfare and laboratory animal science. Her specialist expertise is nationally and internationally recognised in forensics, animal cruelty and toxicology where she acts as an expert witness in criminal and civil legal cases. She is a strong advocate for racing animal welfare, investigating racing animal injury and deaths and conducting research on how to improve animal welfare in sport, society and research. Prof Allavena has an active media profile and has been featured in national and international media including The Conversation, ABC national and regional radio and TV news, commercial and community TV and radio. In 2022-2023 she is a 'Flying Scientist' for Queensland's Office of the Chief Scientist. Rachel really enjoys doing presentations to school students and teachers as well as public outreach events to promote science to the general public. She has presented a TEDx talk on how dogs can help us cure cancer.
Prof Allavena has a PhD in Comparative Medicine from Cornell Univesity in New York, and undertook her pathology specialistation at Ontario Veterinary College. She has worked in drug safety research and development in the pharmaceutical industry in preclinical safety testing and discovery research in the United Kingdom. Her research interests are strongly focused on comparative and translational medicine and animal model validation and development in rodents, dogs and other laboratory animal species. Her major research projects include developing novel cancer immunotherapics and diagnostics for pet dogs naturally suffering from cancer both as a veterinary therapy and comparative model for human cancer. Further, she has extensive research in drivers of koala population decline in SEQLD. She has wide ranging research collaborations specialising in the pathological assessment and study design for animal models in a variety of areas including novel therapeutics, drug safety, toxicology and natural envenomations, biometallic implants, and animal welfare in laboratory animals and domestic species. She is a board certified veterinary anatomic pathologist with the American College of Veterinary Pathologists (ACVP) and a registered specialist veterinary anatomic pathologist with the Veterinary Surgeon's Board of Queensland through the Australian Veterinary Boards Council. She is the lead diagnostic anatomic pathologist in the UQ School of Veterinary Science Veterinary Laboratory Service, and in her professional capacity she oversees cases for Racing Queensland, Queensland Police and RSPCA Queensland, with a special interest in animal welfare and forensic pathology and is a Founding Fellow in Veterinary Forensics with the ACVP. She serves as an expert witness for civil and criminal cases with veterinary relevance. She has an extensive successful track record of training anatomic pathologists for American College of Veterinary Pathology board certification. She was awarded a Faculty of Science Teaching Excellence Award in 2015 and a UQ Citation for Outstanding Contributions to Student Learning in 2021. She has served as an office holder in the Pathobiology chapter of the Australian and New Zealand College of Veterinary Scientists and the Australian Society of Veterinary Pathologists.
Availability
- Professor Rachel Allavena is:
- Not available for supervision
- Media expert
Fields of research
Qualifications
- Bachelor of Veterinary Biology, The University of Queensland
- Bachelor (Honours) of Veterinary Science, The University of Queensland
- Doctor of Philosophy, Cornell University
- Postgraduate Diploma in Veterinary Anatomic Pathology, University of Guelph
Research interests
-
ARC Research Hub for Advanced Manufacturing of Medical Devices (2016–2021)
The project aims to transform Australia's $10.8Bn medical technology sector by developing cost competitive technologies for the rapid production of personalised devices for Endovascular Aneurysm Repair (EVAR). To ensure that the Australian industry remains globally competitive, the Hub seeks to concurrently develop materials, technologies and flexible manufacturing processes. The intended outcomes include more efficient design and manufacturing processes and a new range of EVAR products generating increased market share and higher workforce capability. The resulting impacts are better health outcomes, job creation and providing SMEs with new technologies and skills that can be transferred to the manufacture of products for other sectors. https://researchers.uq.edu.au/research-project/29042
-
Veterinary forensic pathology and animal cruelty
My lab looks at the forensic pathology aspects of animal cruelty cases, as well as the comparative forensics in collaboration with Queensland Forensic and Scientific Services Pathologists. We study the autopsy findings as well as the patterns of animal cruelty in Queensland.
-
Novel immunotherapeutic methods for the treatment of cancer in dogs
We are currently investigating new methods of stimulating the immune system in dogs suffering from a variety of cancers, with the hope of improving survival times and quality of life.
-
UV and sunlight associated skin cancers in dogs
My lab researches the spatial and pathological patterns of skin cancers and skin disease caused by sunlight and UV exposure in pets. As well as the value of preventative measures like sunscreen.
Research impacts
Cancer is common and devastating in our pet dogs and causes heartache for their families. As a veterinary pathologist and immunologist my understanding of disease and immunity drives cures for cancer. For many decades, science relied on mice to help us research cancer, but treatments that work fantastic in mice frequently fail in human patients. My research takes a different approach. I use pet dogs with natural cancer and no hope for other treatments to develop new cancer therapies. Dog cancer is similar in appearance, behaviour, genetics and environmental causes to human cancers. I test novel conventional and immunotherapy treatments. Because dog and human cancer is so similar, dogs provide excellent safety and efficacy information on potential new human treatments. My treatments have cured pets, and are now helping human patients.
Dogs and humans share a special bond, and sadly the cancers that dogs and people develop are very similar. My research group looks at several major common and devastating cancers in pet dogs shared with people; brain cancer, lymphoma, melanoma, osteosarcoma and others. We are conducting trials on novel immunotherapies, which aim to 'wake up' the dog's immune system so it realizes the cancer is there and starts to destroy it. Our treatments include injections into the cancer and vaccinations. Our intratumoural injection resulted in 20% of the dogs being cured of their cancer. These dogs were no longer sick, and their cancer melted away. These dogs also had much longer with their families. Two of our patients were told they only had 2-3 months to live but they survived 12 and 17 months. Another dog was given 8 weeks to live but his cancer disappeared and he lived for 3 more years into old age. The data from these dogs has helped start a hospital trial in human patients with advanced cancer. We only use volunteer pet dogs who have naturally developed their cancer and have no hope for other cures. The pets get to stay with their owners throughout their treatment, which we know is safe for them and their families. Because the cancer in these dogs is natural, it interacts with the dog's body and immune system in a very similar way to how a human cancer does damage. For this reason, we are confident about how well our treatments work, and how safe they will be when they are used to treat human patients. By conducting research on pet dogs with natural cancer, we help the dog, its family and the human patients who will benefit from these new therapies. Dogs are man's best friend in so many ways, and they can help us cure cancer too.
Works
Search Professor Rachel Allavena’s works on UQ eSpace
2019
Journal Article
Canine CD117-Specific Antibodies with Diverse Binding Properties Isolated from a Phage Display Library Using Cell-Based Biopanning
Alfaleh, Mohamed, Arora, Neetika, Yeh, Michael, de Bakker, Christopher, Howard, Christopher, Macpherson, Philip, Allavena, Rachel, Chen, Xiaoli, Harkness, Linda, Mahler, Stephen and Jones, Martina (2019). Canine CD117-Specific Antibodies with Diverse Binding Properties Isolated from a Phage Display Library Using Cell-Based Biopanning. Antibodies, 8 (1) 15, 15. doi: 10.3390/antib8010015
2019
Journal Article
An immunohistochemical study of T and B lymphocyte density in prostatic hyperplasia and prostate carcinoma in dogs
Palmieri, Chiara, Hood, Grace, Fonseca-Alves, Carlos Eduardo, Laufer-Amorim, Renée and Allavena, Rachel (2019). An immunohistochemical study of T and B lymphocyte density in prostatic hyperplasia and prostate carcinoma in dogs. Research in Veterinary Science, 122, 189-192. doi: 10.1016/j.rvsc.2018.11.022
2018
Journal Article
The safety of an adjuvanted autologous cancer vaccine platform in canine cancer patients
Weir, Chris, Oksa, Annika, Millar, Jennifer, Alexander, Miles, Kynoch, Nicola, Walton-Weitz, Zoe, Mackenzie-Wood, Peter, Tam, Felicia, Richards, Hope, Naylor, Richard, Cheng, Katrina, Bennett, Peter, Petrovsky, Nikolai and Allavena, Rachel (2018). The safety of an adjuvanted autologous cancer vaccine platform in canine cancer patients. Veterinary Sciences, 5 (4) 87, 87. doi: 10.3390/vetsci5040087
2018
Journal Article
The effects of mining machinery noise of different amplitudes on the behaviour, faecal corticosterone and tissue morphology of wild mice (Mus musculus)
Mancera, Karen F., Besson, Marie, Lisle, Allan, Allavena, Rachel and Phillips, Clive J. C. (2018). The effects of mining machinery noise of different amplitudes on the behaviour, faecal corticosterone and tissue morphology of wild mice (Mus musculus). Applied Animal Behaviour Science, 203, 81-91. doi: 10.1016/j.applanim.2018.02.010
2018
Conference Publication
Canine and feline bladder disease - Pathologic features and a novel qualitative analysis of pathology reports
Jones, Emily, Palmieri, Chiara, Al-alawneh, John, Jackson, Karen, Thompson, Mary and Allavena, Rachel (2018). Canine and feline bladder disease - Pathologic features and a novel qualitative analysis of pathology reports. Australian Veterinary Association Conference, Brisbane, QLD, Australia, 13-18 May 2018.
2017
Journal Article
Technical skills training for veterinary students: A comparison of simulators and video for teaching standardized cardiac dissection
Allavena, Rachel E., Schaffer-White, Andrea B., Long, Hanna and Alawneh, John I. (2017). Technical skills training for veterinary students: A comparison of simulators and video for teaching standardized cardiac dissection. Journal of Veterinary Medical Education, 44 (4), 620-631. doi: 10.3138/jvme.0516-095R
2017
Journal Article
Pulmonary adiaspiromycosis in critically endangered northern hairy-nosed wombats (Lasiorhinus krefftii)
Schaffer-White, A. B., Harper, D., Mayhew, M., McKinnon, A., Knott, L. and Allavena, R. E. (2017). Pulmonary adiaspiromycosis in critically endangered northern hairy-nosed wombats (Lasiorhinus krefftii). Australian Veterinary Journal, 95 (11), 431-436. doi: 10.1111/avj.12642
2017
Journal Article
The effects of mining machinery noise of different frequencies on the behaviour, faecal corticosterone and tissue morphology of wild mice (Mus musculus)
Mancera, Karen F., Lisle, Allan, Allavena, Rachel and Phillips, Clive J. C. (2017). The effects of mining machinery noise of different frequencies on the behaviour, faecal corticosterone and tissue morphology of wild mice (Mus musculus). Applied Animal Behaviour Science, 197, 81-89. doi: 10.1016/j.applanim.2017.08.008
2017
Journal Article
Congenital bilateral anterior nasal atresia in 16 half-sibling Holstein-Friesian calves
McGowan, M., Smith, C., Ferguson, A., Stone, B., Vankan, D. and Allavena, R. (2017). Congenital bilateral anterior nasal atresia in 16 half-sibling Holstein-Friesian calves. Australian Veterinary Journal, 95 (4), 118-122. doi: 10.1111/avj.12567
2017
Journal Article
Decline causes of koalas in South East Queensland, Australia: a 17-year retrospective study of mortality and morbidity
Gonzalez-Astudillo, Viviana, Allavena, Rachel, McKinnon, Allan, Larkin, Rebecca and Henning, Joerg (2017). Decline causes of koalas in South East Queensland, Australia: a 17-year retrospective study of mortality and morbidity. Scientific Reports, 7 (1) 42587, 42587. doi: 10.1038/srep42587
2017
Conference Publication
The value of citizen science data for passive surveillance of wildlife
Dissanayake, R. B, Stevenson, M., Allavena, R. and Henning, J. (2017). The value of citizen science data for passive surveillance of wildlife. 3rd International Animal Health Surveillance Conference, Rotorua, New Zealand, 30 April - 4 May 2017. Wellington, New Zealand: New Zealand Veterinary Association.
2017
Conference Publication
Canine and feline bladder disease - Pathologic features and a novel qualitative analysis of pathology reports
Jones, Emily, Palmieri, Chiara, Al-alawneh, John, Jackson, Karen, Thompson, Mary and Allavena, Rachel (2017). Canine and feline bladder disease - Pathologic features and a novel qualitative analysis of pathology reports. American College of Veterinary Pathologists, Vancouver, Canada, 4-8 November 2017.
2016
Journal Article
Global or granulosa cell-specific Pten mutations in combination with elevated FSH levels fail to cause ovarian tumours in mice
Upton, Dannielle H., Walters, Kirsty A., Allavena, Rachel E., Jimenez, Mark, Desai, Reena, Handelsman, David J. and Allan, Charles M. (2016). Global or granulosa cell-specific Pten mutations in combination with elevated FSH levels fail to cause ovarian tumours in mice. Hormones and Cancer, 7 (5-6), 316-326. doi: 10.1007/s12672-016-0272-3
2016
Journal Article
Pathological and clinical analysis of vascular catheterization models in rats, with exploration of interventions to improve clinical tolerance
Allavena, Rachel E., West, Heather, Gale, Joanna and Debrue, Marie (2016). Pathological and clinical analysis of vascular catheterization models in rats, with exploration of interventions to improve clinical tolerance. Toxicologic Pathology, 44 (8), 1095-1104. doi: 10.1177/0192623316666197
2016
Conference Publication
Simple and effective tumour immunotherapy using intratumoural complete Freund's adjuvant
Fahrer, A., Carroll, C., Andrew, E., Orange, M. and Allavena, R. (2016). Simple and effective tumour immunotherapy using intratumoural complete Freund's adjuvant. International Congress of Immunology (ICI), Melbourne Australia, 21-26 August 2016. Germany: Wiley.
2016
Conference Publication
Can passive surveillance aid in the understanding of decline of an iconic marsupial? The koala in SEQLD
Gonzalez-Astudillo, V., Allavena, R., Larkin, R., McKinnon, A. and Henning, J. (2016). Can passive surveillance aid in the understanding of decline of an iconic marsupial? The koala in SEQLD. Wildlife Society & Wildlife Disease Association Conference, Christchurch, New Zealand, 23-30 November 2016.
2016
Conference Publication
The koala (Phascolarctos cinereus) in SE QLD: using passive surveillance to understand the decline of an iconic species
Gonzalez-Astudillo, Viviana, Allavena, Rachel E., Henning, Joerg, Larkin, R. and McKinnon, A. (2016). The koala (Phascolarctos cinereus) in SE QLD: using passive surveillance to understand the decline of an iconic species. 4th Oceania Congress for Conservation Biology (OCCB), Brisbane, Australia, 6-8 July 2016. Brisbane, QLD, Australia: Society for Conservation Biology.
2015
Journal Article
The causes and prognoses of different types of fractures in wild koalas submitted to wildlife hospitals
Henning, Joerg, Hannon, Christabel, McKinnon, Allan, Larkin, Rebecca and Allavena, Rachel (2015). The causes and prognoses of different types of fractures in wild koalas submitted to wildlife hospitals. Preventive Veterinary Medicine, 122 (3), 371-378. doi: 10.1016/j.prevetmed.2015.10.015
2015
Journal Article
Regional intravenous limb perfusion compared to systemic intravenous administration for marimastat delivery to equine lamellar tissue
Underwood, C., Collins, S. N., Mills, P. C., Van Eps, A. W., Allavena, R. E., Medina Torres, C. E. and Pollitt, C. C. (2015). Regional intravenous limb perfusion compared to systemic intravenous administration for marimastat delivery to equine lamellar tissue. Journal of Veterinary Pharmacology and Therapeutics, 38 (4), 392-399. doi: 10.1111/jvp.12198
2015
Journal Article
Multiple intra-abdominal serosal myxosarcomas in two koalas (Phascolarctos cinereus)
Astudillo, V. Gonzalez, Schaffer-White, A., Allavena, R. and Palmieri, C. (2015). Multiple intra-abdominal serosal myxosarcomas in two koalas (Phascolarctos cinereus). Journal of Comparative Pathology, 152 (2-3), 283-286. doi: 10.1016/j.jcpa.2015.01.004
Funding
Current funding
Past funding
Supervision
Availability
- Professor Rachel Allavena is:
- Not available for supervision
Supervision history
Current supervision
-
Doctor Philosophy
Analysis of morbidity and mortality causes in Australian Racing animals
Principal Advisor
Other advisors: Professor Joerg Henning
-
Doctor Veterinary Clinical Sci
Decomposition as a diagnostic disrupter: Investigating the extent of tissue distortion and validating management strategies
Principal Advisor
Other advisors: Professor Joerg Henning
-
Doctor Philosophy
Investigation into stem cell markers as potential therapeutic vaccine targets for cancer treatment in dogs
Principal Advisor
Other advisors: Professor Chiara Palmieri, Dr Jose Granados
-
Doctor Philosophy
Making FFPE veterinary tumour samples useful again by building a machine learning enhanced transcriptomic workflow
Associate Advisor
Other advisors: Dr Jose Granados
-
Doctor Philosophy
The epidemiology of interactions between snakes and their anthropogenic environment
Associate Advisor
Other advisors: Professor Joerg Henning
-
Doctor Philosophy
Epidemiological analysis and modelling to predict intracranial diseases, with a focus on brain cancer in dogs
Associate Advisor
Other advisors: Dr Jose Granados, Professor Joerg Henning
-
Doctor Philosophy
Exploring Novel Immunotherapies for Canine Osteosarcoma
Associate Advisor
Other advisors: Dr Halley Ravuri, Dr Jose Granados
Completed supervision
-
2025
Doctor Philosophy
Novel immunotherapeutics in the treatment of cancer in pet dogs: an investigation into the tumour microenvironment
Principal Advisor
Other advisors: Dr Lee McMichael, Dr Karen Jackson, Professor Chiara Palmieri
-
2023
Doctor Veterinary Clinical Sci
Pathology of elapid snake envenomation and sudden unexpected death in cats and dogs in Australia
Principal Advisor
Other advisors: Professor Joerg Henning
-
2023
Master Philosophy
A preliminary analysis of the need to establish educational opportunities in laboratory animal science and medicine in Australia and New Zealand
Principal Advisor
Other advisors: Dr Frances Shapter
-
2020
Doctor Philosophy
Pathological and clinicopathological features of canine and feline bladder disease
Principal Advisor
Other advisors: Dr Karen Jackson, Professor Chiara Palmieri
-
2019
Doctor Philosophy
Analysis of Morbidity and Mortality of Wild Koalas in South-East Queensland using Passive Surveillance Data
Principal Advisor
Other advisors: Professor Joerg Henning
-
2026
Doctor Veterinary Clinical Sci
Decoding Feline Alimentary Lymphoma: Insights from Histology, Immunohistochemistry, and Transcriptomics
Associate Advisor
Other advisors: Professor Chiara Palmieri
-
2023
Doctor Veterinary Clinical Sci
Splenic nodular lesions in dogs
Associate Advisor
Other advisors: Professor Chiara Palmieri
-
2022
Doctor Philosophy
Pathology and pathogenesis of buffalo fly lesions in the skins of cattle
Associate Advisor
Other advisors: Professor Alicja Tabor, Dr Conny Turni
-
2022
Doctor Philosophy
Spatio-temporal analysis of koala sightings and koala mortalities in South East Queensland, 1997 - 2013
Associate Advisor
Other advisors: Professor Joerg Henning
-
2021
Doctor Philosophy
Transcriptome signature of canine osteosarcoma and role of cytokines in the neoplastic growth
Associate Advisor
Other advisors: Dr Karen Jackson, Dr Aaron Herndon, Professor Chiara Palmieri
-
2018
Doctor Philosophy
Studies on avian pathogenic Escherichia coli in commercial broiler Chicken in South East Queensland
Associate Advisor
Other advisors: Dr Conny Turni, Professor Joerg Henning, Dr Justine Gibson
-
2015
Master Philosophy
Refining a 'toolkit' for objective assessment of pain and stress in ruminants
Associate Advisor
Other advisors: Associate Professor Stephen Anderson
Media
Enquiries
Contact Professor Rachel Allavena directly for media enquiries about:
- Animal Cruelty
- Animal Forensics
- Animal health
- Animal Pathology
- Animal Research
- Animal Welfare
- Comparative medicine
- Dog Cancer
- Dogs
- Pet health
- Pet Poisonings
- Pets
- Racing Animals
- Translational medicine
Need help?
For help with finding experts, story ideas and media enquiries, contact our Media team: