Overview
Background
Professor Obermair is the Director of Queensland Centre for Gynaecological Cancer Research (QCGC Research). He is a Professor of Gynaecological Oncology since 2007, a Senior Medical Officer at Royal Brisbane & Women’s Hospital and a Visiting Medical Officer at St Andrews War Memorial Hospital and Buderim Private Hospital. He holds an Honorary title of Professor at UQ since 2006.
Professor Obermair is an internationally recognised leader in gynaecological oncology research and treatment and has lead the research team at QCGC Research since establishing it in 2003.
Availability
- Professor Andreas Obermair is:
- Available for supervision
Fields of research
Qualifications
- Doctoral Diploma of Medicine, International University Vienna
- Royal Australian and New Zealand College of Obstetricians and Gynaecologists, Royal Australian and New Zealand College of Obstetricians and Gynaecologists
Research interests
-
Clinical Trials
Decisions on cancer management ideally are based on the results of high-level evidence, obtained through clinical trials whenever possible. As a principle, a new (proposed better) intervention should be compared to the current standard treatment before being made available generally. Outside a clinical trial new treatments should not become available until evidence has become available to demonstrate superiority over the current standard treatment. Retrospective studies harbour the risk that biases influenced outcomes. At QCGC Research we engage in phase 2 and 3 clinical trials. In large phase trials, patients are allocated randomly to one of two or more interventions in order to minimise the risk of bias. Generally, patients treated within clinical trials have a better outcome compared to patients who are not treated in clinical trials. As the Director of Research Gynaecological Oncology I am currently involved in developing and managing clinical trials in gynaecological cancers.
-
Translational Research
The focus of QCGC Research's translational research program is the application of new technology (molecular, biochemical, imaging and surgical) to prevention, detection and therapy for gynaecological cancers.
-
Quality of Life Research
Cancer specialists are aware that not only the survival time but also the quality of life is a key factor in cancer treatment. This is especially important when two treatments are equally effective but cause different side-effects. My Quality-of-Life research focuses on ovarian, endometrial, cervical and vulval cancer. I wish to provide the best, most effective and modern treatment to my patients with least possible detriments to quality of life.
-
Minimally Invasive Surgery
In Australia, around 30,000 hysterectomies are conducted annually to treat uterine cancer and various benign gynaecological conditions. While open abdominal surgery may be necessary in around 10% of cases, evidence shows that less-invasive approaches, such as total laparoscopic hysterectomy (TLH) can achieve better outcomes for women at a lower overall cost to the health system. Yet, in Queensland, four of ten hysterectomies are still conducted by open abdominal surgery. Our own research has shown that many Australian surgeons are keen to adopt new techniques such as TLH, but that the lack of systematic training and mentoring opportunities is the main impediment to practice-change. Together with gynaecological surgical teams at hospitals and industry support we developed a prototype for system-level transformative practice change in gynaecological surgery.
Research impacts
Professor Obermair is an innovative and skilled gynaecologic oncologist, surgical teacher and consumer advocate. His international leadership and research impact was acknowledged in 2020 by the Australian community, when he was awarded an NHMRC Investigator Fellowship Level 2 (2021-25). The national impact of his research was recognised in 2017, when he was awarded Cancer Australia’s Jeannie Ferris Recognition Award (2017), for outstanding achievements in clinical practice and research. He is deeply engaged in consumer involvement and co-founded and serves on the Board of the Cherish Foundation, a consumer-focussed organisation that funds clinical research in better treatments for women with gynaecological cancers.
Works
Search Professor Andreas Obermair’s works on UQ eSpace
2013
Journal Article
Vaginal cuff dehiscence associated with laparoscopic hysterectomy
Obermair, Andreas (2013). Vaginal cuff dehiscence associated with laparoscopic hysterectomy. Gynecological Surgery, 10 (3), 227-227. doi: 10.1007/s10397-013-0793-5
2013
Journal Article
Differentiating stage I epithelial ovarian cancer from benign disease in women with adnexal tumours using biomarkers or the ROMA algorithm
Kondalsamy-Chennakesavan, S. and Obermair, A. (2013). Differentiating stage I epithelial ovarian cancer from benign disease in women with adnexal tumours using biomarkers or the ROMA algorithm. Gynecologic Oncology, 130 (2), 400-400. doi: 10.1016/j.ygyno.2013.04.471
2013
Journal Article
Impact of weight change and weight cycling on risk of different subtypes of endometrial cancer
Nagle, C. M., Marquart, L., Bain, C. J., O'Brien, S., Lahmann, P. H., Quinn, M., Oehler, M. K., Obermair, A., Spurdle, A. B. and Webb, P. M. (2013). Impact of weight change and weight cycling on risk of different subtypes of endometrial cancer. European Journal of Cancer, 49 (12), 2717-2726. doi: 10.1016/j.ejca.2013.03.015
2013
Journal Article
Silencing of ghrelin receptor expression inhibits endometrial cancer cell growth in vitro and in vivo
Fung, Jenny N. T., Jeffery, Penny L., Lee, John D., Seim, Inge, Roche, Deborah, Obermair, Andreas, Chopin, Lisa K. and Chen, Chen (2013). Silencing of ghrelin receptor expression inhibits endometrial cancer cell growth in vitro and in vivo. American Journal of Physiology-Endocrinology and Metabolism, 305 (2), E305-E313. doi: 10.1152/ajpendo.00156.2013
2013
Journal Article
Feasibility and outcomes of ureteroureterostomy and extravesical ureteroneocystostomy as part of radical surgery for infiltrating gynecologic disease
Hackethal, Andreas, Brennan, Donal J., Land, Russell, Nascimento, Marcelo, Nicklin, James and Obermair, Andreas (2013). Feasibility and outcomes of ureteroureterostomy and extravesical ureteroneocystostomy as part of radical surgery for infiltrating gynecologic disease. International Journal of Gynecological Cancer, 23 (6), 1138-1144. doi: 10.1097/IGC.0b013e3182993790
2013
Journal Article
Improving identification of lynch syndrome patients: A comparison of research data with clinical records
Tan, Yen Y., McGaughran, Julie, Ferguson, Kaltin, Walsh, Michael D., Buchanan, Daniel D., Young, Joanne P., Webb, Penelope M., Obermair, Andreas and Spurdle, Amanda B. (2013). Improving identification of lynch syndrome patients: A comparison of research data with clinical records. International Journal of Cancer, 132 (12), 2876-2883. doi: 10.1002/ijc.27978
2013
Journal Article
Differentiating stage 1 epithelial ovarian cancer from benign ovarian tumours using a combination of tumour markers HE4, CA125, and CEA and patient's age
Kondalsamy-Chennakesavan, Srinivas, Hackethal, Andreas, Bowtell, David and Obermair, Andreas (2013). Differentiating stage 1 epithelial ovarian cancer from benign ovarian tumours using a combination of tumour markers HE4, CA125, and CEA and patient's age. Gynecologic Oncology, 129 (3), 467-471. doi: 10.1016/j.ygyno.2013.03.001
2013
Journal Article
The cost-effectiveness of total laparoscopic hysterectomy compared to total abdominal hysterectomy for the treatment of early stage endometrial cancer
Graves, Nicholas, Janda, Monika, Merollini, Katharina, Gebski, Val and Obermair, Andreas (2013). The cost-effectiveness of total laparoscopic hysterectomy compared to total abdominal hysterectomy for the treatment of early stage endometrial cancer. BMJ Open, 3 (4) e001884, e001884. doi: 10.1136/bmjopen-2012-001884
2013
Journal Article
Aspirin, nonsteroidal anti-inflammatory drugs, paracetamol and risk of endometrial cancer: a case-control study, systematic review and meta-analysis
Neill, Annette S., Nagle, Christina M., Protani, Melinda M., Obermair, Andreas, Spurdle, Amanda B. and Webb, Penelope M. (2013). Aspirin, nonsteroidal anti-inflammatory drugs, paracetamol and risk of endometrial cancer: a case-control study, systematic review and meta-analysis. International Journal of Cancer, 132 (5), 1146-1155. doi: 10.1002/ijc.27717
2013
Journal Article
Nomogram to predict the probability of relapse in patients diagnosed with borderline ovarian tumors
Obermair, Andreas, Tang, Amy, Kondalsamy-Chennakesavan, Srinivas, Ngan, Hextan, Zusterzeel, Petra, Quinn, Michael, Carter, Jonathan, Leung, Yee and Janda, Monika (2013). Nomogram to predict the probability of relapse in patients diagnosed with borderline ovarian tumors. International Journal of Gynecological Cancer, 23 (2), 264-267. doi: 10.1097/IGC.0b013e31827b8844
2013
Journal Article
Endometrial polyp and endometriosis with atypical stromal cells
Russell, Peter, Lynnhtun, Kyaw, James, Daniel and Obermair, Andreas (2013). Endometrial polyp and endometriosis with atypical stromal cells. Pathology, 45 (2), 191-193. doi: 10.1097/PAT.0b013e32835c87b6
2013
Journal Article
A review of complications associated with the surgical treatment of vulvar cancer
Wills, Angela and Obermair, Andreas (2013). A review of complications associated with the surgical treatment of vulvar cancer. Gynecologic Oncology, 131 (2), 467-479. doi: 10.1016/j.ygyno.2013.07.082
2013
Book Chapter
Management of acute and chronic complications of gynecologic cancer treatment
Obermair, Andreas, Ibeanu, Okechukwu A., Jandial, Danielle D., Armstrong, Deborah K. and Bristow, Robert E. (2013). Management of acute and chronic complications of gynecologic cancer treatment. Principles and practice of gynecologic oncology: sixth edition. (pp. 988-1002) Philadelphia, PA USA: Wolters Kluwer Health.
2013
Journal Article
Patterns of chemotherapy treatment for women with invasive epithelial ovarian cancer - A population-based study
Jordan, S., Steer, C., DeFazio, A., Quinn, M., Obermair, A., Friedlander, M., Francis, J., O'Brien, S., Goss, G., Wyld, D. and Webb, P. (2013). Patterns of chemotherapy treatment for women with invasive epithelial ovarian cancer - A population-based study. Gynecologic Oncology, 129 (2), 310-317. doi: 10.1016/j.ygyno.2013.02.007
2013
Journal Article
Differences in epidural and analgesic use in patients with apparent stage I endometrial cancer treated by open versus laparoscopic surgery: results from the randomised LACE trial
Baker, Jannah, Janda, Monika, Belavy, David and Obermair, Andreas (2013). Differences in epidural and analgesic use in patients with apparent stage I endometrial cancer treated by open versus laparoscopic surgery: results from the randomised LACE trial. Minimally Invasive Surgery, 2013 764329. doi: 10.1155/2013/764329
2013
Conference Publication
Survival of Australian women with Epithelial Ovarian Cancer – a Population-based Study
Anuradha, Satyamurthy, Webb, Penlope, Jordon, Susan, Blomfield, P., Leung, Y., Obermair, A., Oehler, M., Quinn, M. and Steer, C. (2013). Survival of Australian women with Epithelial Ovarian Cancer – a Population-based Study. COSA's 40th Annual Scientific Meeting. Cancer Care Coming of Age, Adelaide, SA Australia, 12-14 November 2013. Chichester, West Sussex, United Kingdom: Wiley-Blackwell Publishing. doi: 10.1111/ajco.12144
2013
Conference Publication
Analgesic Requirements and Surgical Outcomes in Patients with and Without Epidural Analgesia in Early Endometrial Cancer: Results From the Randomised Lace Trial
Obermair, A., Baker, J., Janda, M. and Belavy, D. (2013). Analgesic Requirements and Surgical Outcomes in Patients with and Without Epidural Analgesia in Early Endometrial Cancer: Results From the Randomised Lace Trial. _, _, _. London, United Kingdom: BMJ Group.
2013
Journal Article
Epidural analgesia is associated with an increased incidence of postoperative complications in patients requiring an abdominal hysterectomy for early stage endometrial cancer
Belavy, D., Janda, M., Baker, J. and Obermair, A. (2013). Epidural analgesia is associated with an increased incidence of postoperative complications in patients requiring an abdominal hysterectomy for early stage endometrial cancer. Gynecologic Oncology, 131 (2), 423-429. doi: 10.1016/j.ygyno.2013.08.027
2012
Journal Article
Risk factors to predict the incidence of surgical adverse events following open or laparoscopic surgery for apparent early stage endometrial cancer: results from a randomised controlled trial
Kondalsamy-Chennakesavan, Srinivas, Janda, Monika, Gebski, Val, Baker, Jannah, Brand, Alison, Hogg, Russell, Jobling, Thomas W., Land, Russell, Manolitsas, Tom, Nascimento, Marcelo, Neesham, Deborah, Nicklin, James L., Oehler, Martin K., Otton, Geoff, Perrin, Lewis, Salfinger, Stuart, Hammond, Ian, Leung, Yee, Sykes, Peter, Ngan, Hextan, Garrett, Andrea, Laney, Michael, Tong Yow Ng, Tam, Karfai, Chan, Karen, Wrede, David H., Pather, Selvan, Simcock, Bryony, Farrell, Rhonda ... Obermair, Andreas (2012). Risk factors to predict the incidence of surgical adverse events following open or laparoscopic surgery for apparent early stage endometrial cancer: results from a randomised controlled trial. European Journal of Cancer, 48 (14), 2155-2162. doi: 10.1016/j.ejca.2012.03.013
2012
Journal Article
Prognostic value of elevated preoperative serum CA125 in ovarian tumors of low malignant potential: A multinational collaborative study (ANZGOG0801)
Tang, Amy, Kondalsamy-Chennakesavan, Srinivas, Ngan, Hextan, Zusterzeel, Petra, Quinn, Michael, Carter, Jonathan, Leung, Yee and Obermair, Andreas (2012). Prognostic value of elevated preoperative serum CA125 in ovarian tumors of low malignant potential: A multinational collaborative study (ANZGOG0801). Gynecologic Oncology, 126 (1), 36-40. doi: 10.1016/j.ygyno.2012.02.031
Funding
Current funding
Past funding
Supervision
Availability
- Professor Andreas Obermair is:
- Available for supervision
Before you email them, read our advice on how to contact a supervisor.
Available projects
-
feMMe: Uterus-preserving treatment of endometrial cancer
In 2020 we completed the feMMe, phase 2 cliniccal trial which established anticancer activity of levonorgestrel intrauterrine device (LNG-IUD) to treat endometrial cancer. The next two steps towards estabnlioshing this treatment for larger groups of patients include:
1. To determine factors that predict response to LNG-IUD
2. To determine long-term patient outcomes including survival, fertility, and patient needs.
-
Improving Quality of Survival for Women with Gynaecological Cancer
- Focus on improving quality of life, health & function during & after gynaecological cancer treatment, with a focus on biomarker research, implementation research and cancer survivorship.
Supervision history
Current supervision
-
Doctor Philosophy
Advanced methods for biomarker informed endometrial cancer
Principal Advisor
Other advisors: Dr Eva Baxter, Dr Zoe West, Professor Andrew Martin
-
Master Philosophy
Patterns of care in endometrial cancer management in Queensland: a retrospective analysis.
Principal Advisor
Other advisors: Dr Eva Baxter
-
Doctor Philosophy
Diet quality and composition in Australian women with endometrial cancer
Associate Advisor
Other advisors: Professor Monika Janda
Completed supervision
-
2014
Doctor Philosophy
Hereditary endometrial cancer: Improving identification and referral of patients with suspected Lynch syndrome
Principal Advisor
Other advisors: Honorary Professor Amanda Spurdle, Associate Professor Lisa Fitzgerald
-
2008
Doctor Philosophy
Nutritional status of patients with gynaecological cancer -
Joint Principal Advisor
Other advisors: Emeritus Professor Geoffrey Cleghorn
-
Media
Enquiries
For media enquiries about Professor Andreas Obermair's areas of expertise, story ideas and help finding experts, contact our Media team: