
Overview
Background
Educated at the University of Copenhagen, Denmark, and the Australian National University, Canberra. Career at the Université de Lausanne, Switzerland, and the Universität Marburg, Germany. Professor and Chair of Organic Chemistry and Head of the Organic Chemistry Section, The University of Queensland from 1985. Emeritus professor from 2008. Chair of the National Committee for Chemistry of the Australian Academy of Science 2009-2014. Editor-in-Chief, Australian Journal of Chemistry 2008-15. Editor, Journal of Analytical and Applied Pyrolysis (Elsevier, IF 3.65) 2016-. Visiting Professor Université de Pau, France, 2011-19; Visiting Professor University of Kuwait 2014-18; Visiting Professor / Special Appointed Professor Hiroshima University 2014-18. Fellow of the Australian Academy of Science. Centenary Medal of the Australian Commonwealth 2003 for research in organic and physical chemistry. David Craig Medal of the Academy of Science 2014 for research in chemistry. JSPS Fellowship (Japan) 2014. Honorary doctorate, University of Pau, France, 2014. A.J. Birch Medal of the Royal Australian Chemical Institute (RACI) for ecellence in research in organic chemistry, 2014. Leighton Medal of the RACI 2018.
Research on Unusual Molecules and Reactive Intermediates: Synthesis and Reaction Mechanism. Heterocyclic chemistry. Pyrolysis reactions. Photochemistry
Research in the Wentrup group is concerned with the discovery of novel types of molecules with new and unusual bonding patterns. Such molecules are mostly highly reactive, and special methods are required both for their generation and for their detection. The group has developed these methods over many years and acquired world-class equipment for these purposes, including flash vacuum thermolysis apparatus, cryostats for matrix isolation of reaction products at cryogenic temperatures (down to 7 K), matrix and solution photochemistry equipment, infrared, UV and mass spectrometers, as well as modern computational facilities.
This research has resulted in the synthesis and characterization of many novel compounds, including extended cumulenes of the types RN=C=C=C=X, which themselves are used in the synthesis of many novel types of molecules, some of them of potential pharmaceutical interest (quinolone antibiotics; diazepines).
The research group has a world reputation in the field of carbene and nitrene chemistry, involving reactive intermediates with sextet carbon or nitrogen. These species are also very useful in synthesis, for example in the preparation of diazepines and diazepinones, a family of pharmaceutically interesting compounds. Numerous mechanistic studies and synthetic applications of ketenes have been carried out in our group.
Active collaborations are ongoing with scientists in Australia (UQ and CSIRO), China (Suzhou), France (Pau), Germany (Oldenburg), Japan (Hiroshima), Spain (Donostia - San Sebastian), and Portugal (Coimbra).
Availability
- Emeritus Professor Curt Wentrup is:
- Not available for supervision
- Media expert
Fields of research
Qualifications
- Doctor of Philosophy, Australian National University
- Doctor of Philosophy of Science (Advanced), University of Copenhagen
- Doctoral Diploma, Institution to be confirmed
- Australian Academy of Science, Australian Academy of Science
- Royal Australian Chemical Institute, Royal Australian Chemical Institute
Research interests
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Organic, physical, and historical chemistry
Reactive intermediates, pyrolysis, photochemistry, reaction mechanism. History of science.
Research impacts
This research leads to the development of new pharmaceuticals, e.g. new antibiotics (quinolones and naphthyridones) and new leads towards a treatment for scizophrenia (diazepine molecules).
Chemical industry has used our pyrolysis techniques in specialized manufacturing processes.
Our analytical/spectroscopic work has led to cooperation with chemical and energy firms and agencies involved in forensic science, and our research has generated collaborations with many scientists at universities in Australia, Austria, Belgium, China, Denmark, France, Germany, Hungary, Japan, Portugal, Singapore, Switzerland, and USA.
Works
Search Professor Curt Wentrup’s works on UQ eSpace
1991
Journal Article
2,5-Dithiacyclopentylideneketene and Ethenedithione, S=C=C=S, Generated by Flash Vacuum Pyrolysis
Wentrup C., Kambouris P., Evans R.A., Owen D., Macfarlane G., Chuche J., Pommelet J.C., Cheikh A.B., Plisnier M. and Flammang R. (1991). 2,5-Dithiacyclopentylideneketene and Ethenedithione, S=C=C=S, Generated by Flash Vacuum Pyrolysis. Journal of the American Chemical Society, 113 (8), 3130-3135. doi: 10.1021/ja00008a048
1991
Journal Article
Direct observation of α-oxo ketenes formed from 1,3-dioxin-4-ones and the enols of β-keto esters
Freiermuth B. and Wentrup C. (1991). Direct observation of α-oxo ketenes formed from 1,3-dioxin-4-ones and the enols of β-keto esters. Journal of Organic Chemistry, 56 (7), 2286-2289. doi: 10.1021/jo00007a008
1990
Journal Article
Identification of the transient benzonitrile n-sulfide by flash-vacuum pyrolysis and neutralization-reionization mass spectrometry
Maquestiau A., Flammang R., Plisnier M., Wentrup C., Kambouris P., Paton M.R. and Terlouw J.K. (1990). Identification of the transient benzonitrile n-sulfide by flash-vacuum pyrolysis and neutralization-reionization mass spectrometry. International Journal of Mass Spectrometry and Ion Processes, 100 (C), 477-488. doi: 10.1016/0168-1176(90)85090-O
1990
Journal Article
Flash‐vacuum pyrolysis of 1‐acylbenzotriazole: Direct observation of cyclopenta‐2,4‐dienylidenemethaneimines by tandem mass spectrometry and low‐temperature infrared spectrometry
Maquestiau A., Beugnies D., Flammang R., Freiermuth B. and Wentrup C. (1990). Flash‐vacuum pyrolysis of 1‐acylbenzotriazole: Direct observation of cyclopenta‐2,4‐dienylidenemethaneimines by tandem mass spectrometry and low‐temperature infrared spectrometry. Organic Mass Spectrometry, 25 (4), 197-203. doi: 10.1002/oms.1210250404
1989
Journal Article
CONFIRMATION OF THE ELECTRIC-FIELD GRADIENTS AT THE NITROGEN NUCLEI IN N-CYANOMETHANIMINE, CH2NCN, FROM LOW-J ROTATIONAL TRANSITIONS
STOLZE, WH, SUTTER, DH and WENTRUP, C (1989). CONFIRMATION OF THE ELECTRIC-FIELD GRADIENTS AT THE NITROGEN NUCLEI IN N-CYANOMETHANIMINE, CH2NCN, FROM LOW-J ROTATIONAL TRANSITIONS. Zeitschrift Fur Naturforschung Section A-A Journal of Physical Sciences, 44 (4), 291-294.
1988
Journal Article
A new example of internal oxidation of remote groups in organic nitroaromatic ions
Maquestiau A., Flammang R., Flammang-Barbieux M., Chen L.-Z. and Wentrup C. (1988). A new example of internal oxidation of remote groups in organic nitroaromatic ions. International Journal of Mass Spectrometry and Ion Processes, 86 (C), 235-249. doi: 10.1016/0168-1176(88)80068-5
1988
Journal Article
Dinitrogen sulfide, N2S, revealed by photoelectron spectroscopy
Bender, Harald, Carnovale, Frank, Barrie, Peel J. and Wentrup, Curt (1988). Dinitrogen sulfide, N2S, revealed by photoelectron spectroscopy. Journal of the American Chemical Society, 110 (11), 3458-3461. doi: 10.1021/ja00219a019
1988
Journal Article
PRIMARY ETHYNAMINES (HC=CNH2, PHC=CNH2), AMINOPROPADIENONE (H2NCH=C=C=O), AND IMIDOYLKETENE (HN=CHCH=C=O) - PREPARATION AND IDENTIFICATION OF MOLECULES OF COSMOCHEMICAL INTEREST
WENTRUP, C, BRIEHL, H, LORENCAK, P, VOGELBACHER, UJ, WINTER, HW, MAQUESTIAU, A and FLAMMANG, R (1988). PRIMARY ETHYNAMINES (HC=CNH2, PHC=CNH2), AMINOPROPADIENONE (H2NCH=C=C=O), AND IMIDOYLKETENE (HN=CHCH=C=O) - PREPARATION AND IDENTIFICATION OF MOLECULES OF COSMOCHEMICAL INTEREST. Journal of the American Chemical Society, 110 (5), 1337-1343. doi: 10.1021/ja00213a002
1988
Journal Article
Interrelationship between carboxy(vinyl)ketenes, methyleneketenes, vinylketenes, and hydroxyacetylenes
Wentrup C. and Lorencak P. (1988). Interrelationship between carboxy(vinyl)ketenes, methyleneketenes, vinylketenes, and hydroxyacetylenes. Journal of the American Chemical Society, 110 (6), 1880-1883. doi: 10.1021/ja00214a035
1988
Journal Article
Benzyne, cyclohexyne, and 3-azacyclohexyne and the problem of cycloalkyne versus cycloalkylideneketene genesis
Wentrup C., Blanch R., Briehl H. and Gross G. (1988). Benzyne, cyclohexyne, and 3-azacyclohexyne and the problem of cycloalkyne versus cycloalkylideneketene genesis. Journal of the American Chemical Society, 110 (6), 1874-1880. doi: 10.1021/ja00214a034
1987
Journal Article
CORRECTION
WENTRUP, C (1987). CORRECTION. Chemical Physics Letters, 139 (6), 613-613. doi: 10.1016/0009-2614(87)87353-0
1987
Journal Article
Benzothiet-2-ones: Synthesis, Reactions, and Comparison with Benzoxet-2-ones and Benzazetin-2-ones
Wentrup C., Bender H. and Gross G. (1987). Benzothiet-2-ones: Synthesis, Reactions, and Comparison with Benzoxet-2-ones and Benzazetin-2-ones. Journal of Organic Chemistry, 52 (17), 3838-3847. doi: 10.1021/jo00226a022
1987
Journal Article
C2H2N2 Isomers in the Gas-Phase - Characterization of Ch2=N-Cn and Hn=Ch-Cn by Collisional Activation Mass-Spectrometry
Wentrup, C, Lorencak, P, Maquestiau, A and Flammang, R (1987). C2H2N2 Isomers in the Gas-Phase - Characterization of Ch2=N-Cn and Hn=Ch-Cn by Collisional Activation Mass-Spectrometry. Chemical Physics Letters, 137 (3), 241-244. doi: 10.1016/0009-2614(87)80212-9
1987
Journal Article
FLASH PYROLYSIS OF 1,4-BIS(5-TETRAZOLYL)BENZENE - ENTRY TO THE C8H6 ENERGY SURFACE
BAUM, MW, FONT, JL, MEISLICH, ME, WENTRUP, C and JONES, M (1987). FLASH PYROLYSIS OF 1,4-BIS(5-TETRAZOLYL)BENZENE - ENTRY TO THE C8H6 ENERGY SURFACE. Journal of the American Chemical Society, 109 (8), 2534-2536. doi: 10.1021/ja00242a060
1987
Journal Article
GAS-PHASE REACTIONS .61. NITRILE IMINES RC=+N--N-SI(CH3)3 - OPTIMIZATION OF GAS-PHASE SYNTHESIS AND ASSIGNMENT OF THEIR PHOTOELECTRON-SPECTRA
BOCK, H, DAMMEL, R, FISCHER, S and WENTRUP, C (1987). GAS-PHASE REACTIONS .61. NITRILE IMINES RC=+N--N-SI(CH3)3 - OPTIMIZATION OF GAS-PHASE SYNTHESIS AND ASSIGNMENT OF THEIR PHOTOELECTRON-SPECTRA. Tetrahedron Letters, 28 (6), 617-620. doi: 10.1016/S0040-4039(00)95795-2
1986
Journal Article
Iminoacetonitrile, An Hcn Dimer - Ir Identification in An Argon Matrix
Lorencak, P, Raabe, G, Radziszewski, JJ and Wentrup, C (1986). Iminoacetonitrile, An Hcn Dimer - Ir Identification in An Argon Matrix. Journal of the Chemical Society-Chemical Communications, 96 (12), 916-918. doi: 10.1039/c39860000916
1986
Journal Article
Dinitrogen Sulfide
Wentrup, C, Fischer, S, Maquestiau, A and Flammang, R (1986). Dinitrogen Sulfide. Journal of Organic Chemistry, 51 (10), 1908-1910. doi: 10.1021/jo00360a051
1986
Journal Article
Unsaturated Ketenes - a Study of Their Formation and Rearrangement by Tandem Mass-Spectrometry and Low-Temperature Infrared-Spectroscopy
Maquestiau, A, Pauwels, P, Flammang, R, Lorencak, P and Wentrup, C (1986). Unsaturated Ketenes - a Study of Their Formation and Rearrangement by Tandem Mass-Spectrometry and Low-Temperature Infrared-Spectroscopy. Organic Mass Spectrometry, 21 (5), 259-265. doi: 10.1002/oms.1210210505
1986
Journal Article
A STABLE METHYLENEKETENE AND THE STEPWISE FRAGMENTATION OF MELDRUMS ACIDS
LORENCAK, P, POMMELET, JC, CHUCHE, J and WENTRUP, C (1986). A STABLE METHYLENEKETENE AND THE STEPWISE FRAGMENTATION OF MELDRUMS ACIDS. Journal of the Chemical Society-Chemical Communications (5), 369-370. doi: 10.1039/c39860000369
1986
Journal Article
DIAZAFULVENONES - THERMAL ISOMERIZATIONS AND ELIMINATIONS IN ALKOXYCARBONYL AND ANILINOCARBONYL DERIVATIVES OF IMIDAZOLE
MAQUESTIAU, A, TOMMASETTI, A, PEDREGALFREIRE, C, ELGUERO, J, FLAMMANG, R, WIERSUM, UE, BENDER, H and WENTRUP, C (1986). DIAZAFULVENONES - THERMAL ISOMERIZATIONS AND ELIMINATIONS IN ALKOXYCARBONYL AND ANILINOCARBONYL DERIVATIVES OF IMIDAZOLE. Journal of Organic Chemistry, 51 (3), 306-309. doi: 10.1021/jo00353a006
Funding
Supervision
Availability
- Emeritus Professor Curt Wentrup is:
- Not available for supervision
Supervision history
Completed supervision
-
2006
Doctor Philosophy
SYNTHESES AND REACTIONS OF IMINOPROPADIENONES, SYDNONES AND OXAZINONES
Principal Advisor
Other advisors: Professor Craig Williams
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2002
Doctor Philosophy
HETEROCYCLIC SYNTHESIS BASED ON IMINOPROPADIENONES
Principal Advisor
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2002
Doctor Philosophy
SYNTHESIS AND CHARACTERISATION OF 1,3- and 1,4- DIAZEPINES AND DERIVATIVES
Principal Advisor
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Doctor Philosophy
NITRENES REARRANGEMENTS: FORMATION OF REACTIVE INTERMEDIATES AND UNUSUAL MOLECULES
Principal Advisor
Other advisors: Professor Craig Williams
Media
Enquiries
Contact Emeritus Professor Curt Wentrup directly for media enquiries about:
- Organic reaction mechanisms
- Photochemistry
- Pyrolysis
- Reactive intermediates
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