
Overview
Background
Educated at the University of Copenhagen, Denmark, and the Australian National University, Canberra. Career at the Université de Lausanne, Switzerland, and the Universität Marburg, Germany. Professor and Chair of Organic Chemistry and Head of the Organic Chemistry Section, The University of Queensland from 1985. Emeritus professor from 2008. Chair of the National Committee for Chemistry of the Australian Academy of Science 2009-2014. Editor-in-Chief, Australian Journal of Chemistry 2008-15. Editor, Journal of Analytical and Applied Pyrolysis (Elsevier, IF 3.65) 2016-. Visiting Professor Université de Pau, France, 2011-19; Visiting Professor University of Kuwait 2014-18; Visiting Professor / Special Appointed Professor Hiroshima University 2014-18. Fellow of the Australian Academy of Science. Centenary Medal of the Australian Commonwealth 2003 for research in organic and physical chemistry. David Craig Medal of the Academy of Science 2014 for research in chemistry. JSPS Fellowship (Japan) 2014. Honorary doctorate, University of Pau, France, 2014. A.J. Birch Medal of the Royal Australian Chemical Institute (RACI) for ecellence in research in organic chemistry, 2014. Leighton Medal of the RACI 2018.
Research on Unusual Molecules and Reactive Intermediates: Synthesis and Reaction Mechanism. Heterocyclic chemistry. Pyrolysis reactions. Photochemistry
Research in the Wentrup group is concerned with the discovery of novel types of molecules with new and unusual bonding patterns. Such molecules are mostly highly reactive, and special methods are required both for their generation and for their detection. The group has developed these methods over many years and acquired world-class equipment for these purposes, including flash vacuum thermolysis apparatus, cryostats for matrix isolation of reaction products at cryogenic temperatures (down to 7 K), matrix and solution photochemistry equipment, infrared, UV and mass spectrometers, as well as modern computational facilities.
This research has resulted in the synthesis and characterization of many novel compounds, including extended cumulenes of the types RN=C=C=C=X, which themselves are used in the synthesis of many novel types of molecules, some of them of potential pharmaceutical interest (quinolone antibiotics; diazepines).
The research group has a world reputation in the field of carbene and nitrene chemistry, involving reactive intermediates with sextet carbon or nitrogen. These species are also very useful in synthesis, for example in the preparation of diazepines and diazepinones, a family of pharmaceutically interesting compounds. Numerous mechanistic studies and synthetic applications of ketenes have been carried out in our group.
Active collaborations are ongoing with scientists in Australia (UQ and CSIRO), China (Suzhou), France (Pau), Germany (Oldenburg), Japan (Hiroshima), Spain (Donostia - San Sebastian), and Portugal (Coimbra).
Availability
- Emeritus Professor Curt Wentrup is:
- Not available for supervision
- Media expert
Fields of research
Qualifications
- Doctor of Philosophy, Australian National University
- Doctor of Philosophy of Science (Advanced), University of Copenhagen
- Doctoral Diploma, Institution to be confirmed
- Australian Academy of Science, Australian Academy of Science
- Royal Australian Chemical Institute, Royal Australian Chemical Institute
Research interests
-
Organic, physical, and historical chemistry
Reactive intermediates, pyrolysis, photochemistry, reaction mechanism. History of science.
Research impacts
This research leads to the development of new pharmaceuticals, e.g. new antibiotics (quinolones and naphthyridones) and new leads towards a treatment for scizophrenia (diazepine molecules).
Chemical industry has used our pyrolysis techniques in specialized manufacturing processes.
Our analytical/spectroscopic work has led to cooperation with chemical and energy firms and agencies involved in forensic science, and our research has generated collaborations with many scientists at universities in Australia, Austria, Belgium, China, Denmark, France, Germany, Hungary, Japan, Portugal, Singapore, Switzerland, and USA.
Works
Search Professor Curt Wentrup’s works on UQ eSpace
1996
Journal Article
Novel heterocumulene (RN=C=C=C=X) and ketene rearrangements
Wentrup C., Fulloon B.E., Moloney D.W.J., Bibas H. and Wong M.W. (1996). Novel heterocumulene (RN=C=C=C=X) and ketene rearrangements. Pure and Applied Chemistry, 68 (4), 891-894. doi: 10.1351/pac199668040891
1996
Journal Article
(Cyanovinyl)ketenes from azafulvenones. An apparent retro-Wolff rearrangement
Qiao, GGH, Meutermans, W, Wong, MW, Traubel, M and Wentrup, C (1996). (Cyanovinyl)ketenes from azafulvenones. An apparent retro-Wolff rearrangement. Journal of the American Chemical Society, 118 (16), 3852-3861. doi: 10.1021/ja954226r
1996
Journal Article
Synthesis of 1H- and 5H-1,3-diazepines from azido- and tetrazolo-pyridines
Reisinger, A and Wentrup, C (1996). Synthesis of 1H- and 5H-1,3-diazepines from azido- and tetrazolo-pyridines. Chemical Communications (7), 813-814. doi: 10.1039/cc9960000813
1996
Journal Article
The cheletropic trapping of nitric oxide by the bis-ketene 1,2-dicarbonylcyclohexa-3,5-diene and the diene 3,4-diphenyl-2,5-dimethyl-2,4-hexadiene.
Adam, W, Bottle, SE, Grice, ID, Pfeiler, D and Wentrup, C (1996). The cheletropic trapping of nitric oxide by the bis-ketene 1,2-dicarbonylcyclohexa-3,5-diene and the diene 3,4-diphenyl-2,5-dimethyl-2,4-hexadiene.. Tetrahedron Letters, 37 (12), 2113-2116. doi: 10.1016/0040-4039(96)00206-7
1996
Journal Article
Photochemistry of deuterated acetylketenes: Matrix isolation infrared spectroscopic and ab initio studies
Zuhse, RH, Wong, MW and Wentrup, C (1996). Photochemistry of deuterated acetylketenes: Matrix isolation infrared spectroscopic and ab initio studies. Journal of Physical Chemistry, 100 (10), 3917-3922. doi: 10.1021/jp9529026
1996
Journal Article
Imidoylketene-oxoketenimine interconversion. Rearrangement of a carbomethoxyketenimine to a methoxyimidoylketene and 2-methoxy-4-quinolone
Fulloon B.E. and Wentrup C. (1996). Imidoylketene-oxoketenimine interconversion. Rearrangement of a carbomethoxyketenimine to a methoxyimidoylketene and 2-methoxy-4-quinolone. Journal of Organic Chemistry, 61 (4), 1363-1367. doi: 10.1021/jo951832w
1995
Journal Article
Polycarbon Disulfides Scns (N=1-3) and Their Protonated and Methylated Forms (Hcns2+ and Ch3Cns2+) - Tandem Mass-Spectrometry and Ab-Initio Mo Study
Wong, MW, Wentrup, C and Flammang, R (1995). Polycarbon Disulfides Scns (N=1-3) and Their Protonated and Methylated Forms (Hcns2+ and Ch3Cns2+) - Tandem Mass-Spectrometry and Ab-Initio Mo Study. Journal of Physical Chemistry, 99 (46), 16849-16856. doi: 10.1021/j100046a010
1995
Journal Article
IMIDOYLKETENE OXOKETENIMINE REARRANGEMENT - FACILE 1,3-SHIFT OF AN ALKOXY GROUP
FULLOON, B, ELNABI, HAA, KOLLENZ, G and WENTRUP, C (1995). IMIDOYLKETENE OXOKETENIMINE REARRANGEMENT - FACILE 1,3-SHIFT OF AN ALKOXY GROUP. Tetrahedron Letters, 36 (36), 6547-6550. doi: 10.1016/0040-4039(95)01283-N
1995
Journal Article
Vinylketene-Acylallene Rearrangement
Bibas, H, Wong, MW and Wentrup, C (1995). Vinylketene-Acylallene Rearrangement. Journal of the American Chemical Society, 117 (37), 9582-9583. doi: 10.1021/ja00142a034
1995
Journal Article
A Remarkably Stable Linear Ketenimine
Wolf, R, Wong, MW, Kennard, Chl and Wentrup, C (1995). A Remarkably Stable Linear Ketenimine. Journal of the American Chemical Society, 117 (25), 6789-6790. doi: 10.1021/ja00130a023
1995
Journal Article
3-carbonyl-3H-indole: Direct observation and tetramerization to a tetrabenzoporphyrin analogue
Qiao G.G. and Wentrup C. (1995). 3-carbonyl-3H-indole: Direct observation and tetramerization to a tetrabenzoporphyrin analogue. Tetrahedron Letters, 36 (22), 3913-3916. doi: 10.1016/0040-4039(95)00640-X
1995
Journal Article
(ALPHA)-OXOKETENES - PREPARATION AND CHEMISTRY (DEC, PG 1219, 1994)
WENTRUP, C, HEILMAYER, W and KOLLENZ, G (1995). (ALPHA)-OXOKETENES - PREPARATION AND CHEMISTRY (DEC, PG 1219, 1994). Synthesis-Stuttgart (3), 343-343. doi: 10.1055/s-1994-25673
1995
Conference Publication
Ketene rearrangements and 1,3-shifts
Wentrup, C and Wong, MW (1995). Ketene rearrangements and 1,3-shifts. 3rd Latin-American Conference on Organic Physical Chemistry, Florianopolis Brazil, Apr 09-14, 1995. 88040-900 FLORIANOPOLIS: UNIVERSIDADE FEDERAL SANTA CATARINA.
1995
Journal Article
A convenient de novo synthesis of functionalised 2,4,6,8- tetraoxaadamantanes
Heilmayer W., Dalvi T.S., Kappe C.O., Wentrup C., Gruber K., Sterk H. and Kollenz G. (1995). A convenient de novo synthesis of functionalised 2,4,6,8- tetraoxaadamantanes. Journal of the Chemical Society-Chemical Communications (7), 797-798. doi: 10.1039/C39950000797
1995
Journal Article
The use of 1, 2-shifts in carbenes and nitrenes in the generation of novel heterocumulenes
Wentrup, Curt, Kappe, C. Oliver and Wong, Ming Wah (1995). The use of 1, 2-shifts in carbenes and nitrenes in the generation of novel heterocumulenes. Pure and Applied Chemistry, 67 (5), 749-754. doi: 10.1351/pac199567050749
1995
Journal Article
Polycarbon Sulfides Cns (N=2-6) and Corresponding Hydrides Hcns - Neutralization-Reionization Mass-Spectrometry and Ab-Initio Molecular-Orbital Study
Flammang, R, Vanhaverbeke, Y, Wong, MW and Wentrup, C (1995). Polycarbon Sulfides Cns (N=2-6) and Corresponding Hydrides Hcns - Neutralization-Reionization Mass-Spectrometry and Ab-Initio Molecular-Orbital Study. Rapid Communications in Mass Spectrometry, 9 (3), 203-208. doi: 10.1002/rcm.1290090305
1995
Conference Publication
The use of 1, 2-shifts in carbenes and nitrenes in the generation of novel heterocumulenes
Wentrup, C., Kappe, C. O. and Wong, M. W. (1995). The use of 1, 2-shifts in carbenes and nitrenes in the generation of novel heterocumulenes. 12th International Conference on Physical Organic Chemistry, Padua Italy, 28 August -9 September 1994. Oxford United Kingdom: Wiley-Blackwell. doi: 10.1351/pac199567050749
1995
Journal Article
Acetylketene: Conformational isomerism and photochemistry. Matrix isolation infrared and ab initio studies
Kappe C.O., Wong M.W. and Wentrup C. (1995). Acetylketene: Conformational isomerism and photochemistry. Matrix isolation infrared and ab initio studies. Journal of Organic Chemistry, 60 (6), 1686-1695. doi: 10.1021/jo00111a029
1994
Journal Article
ALPHA-OXOKETENES - PREPARATION AND CHEMISTRY
WENTRUP, C, HEILMAYER, W and KOLLENZ, G (1994). ALPHA-OXOKETENES - PREPARATION AND CHEMISTRY. Synthesis-Stuttgart, 1219-1248. doi: 10.1055/s-1994-25673
1994
Journal Article
Ketene-Ketene Rearrangement - Substituent Effects An the 1,3-Migration in Alpha-Oxo Ketenes
Wong, MW and Wentrup, C (1994). Ketene-Ketene Rearrangement - Substituent Effects An the 1,3-Migration in Alpha-Oxo Ketenes. Journal of Organic Chemistry, 59 (18), 5279-5285. doi: 10.1021/jo00097a033
Funding
Supervision
Availability
- Emeritus Professor Curt Wentrup is:
- Not available for supervision
Supervision history
Completed supervision
-
2006
Doctor Philosophy
SYNTHESES AND REACTIONS OF IMINOPROPADIENONES, SYDNONES AND OXAZINONES
Principal Advisor
Other advisors: Professor Craig Williams
-
2002
Doctor Philosophy
HETEROCYCLIC SYNTHESIS BASED ON IMINOPROPADIENONES
Principal Advisor
-
2002
Doctor Philosophy
SYNTHESIS AND CHARACTERISATION OF 1,3- and 1,4- DIAZEPINES AND DERIVATIVES
Principal Advisor
-
Doctor Philosophy
NITRENES REARRANGEMENTS: FORMATION OF REACTIVE INTERMEDIATES AND UNUSUAL MOLECULES
Principal Advisor
Other advisors: Professor Craig Williams
Media
Enquiries
Contact Emeritus Professor Curt Wentrup directly for media enquiries about:
- Organic reaction mechanisms
- Photochemistry
- Pyrolysis
- Reactive intermediates
Need help?
For help with finding experts, story ideas and media enquiries, contact our Media team: