
Overview
Background
Educated at the University of Copenhagen, Denmark, and the Australian National University, Canberra. Career at the Université de Lausanne, Switzerland, and the Universität Marburg, Germany. Professor and Chair of Organic Chemistry and Head of the Organic Chemistry Section, The University of Queensland from 1985. Emeritus professor from 2008. Chair of the National Committee for Chemistry of the Australian Academy of Science 2009-2014. Editor-in-Chief, Australian Journal of Chemistry 2008-15. Editor, Journal of Analytical and Applied Pyrolysis (Elsevier, IF 3.65) 2016-. Visiting Professor Université de Pau, France, 2011-19; Visiting Professor University of Kuwait 2014-18; Visiting Professor / Special Appointed Professor Hiroshima University 2014-18. Fellow of the Australian Academy of Science. Centenary Medal of the Australian Commonwealth 2003 for research in organic and physical chemistry. David Craig Medal of the Academy of Science 2014 for research in chemistry. JSPS Fellowship (Japan) 2014. Honorary doctorate, University of Pau, France, 2014. A.J. Birch Medal of the Royal Australian Chemical Institute (RACI) for ecellence in research in organic chemistry, 2014. Leighton Medal of the RACI 2018.
Research on Unusual Molecules and Reactive Intermediates: Synthesis and Reaction Mechanism. Heterocyclic chemistry. Pyrolysis reactions. Photochemistry
Research in the Wentrup group is concerned with the discovery of novel types of molecules with new and unusual bonding patterns. Such molecules are mostly highly reactive, and special methods are required both for their generation and for their detection. The group has developed these methods over many years and acquired world-class equipment for these purposes, including flash vacuum thermolysis apparatus, cryostats for matrix isolation of reaction products at cryogenic temperatures (down to 7 K), matrix and solution photochemistry equipment, infrared, UV and mass spectrometers, as well as modern computational facilities.
This research has resulted in the synthesis and characterization of many novel compounds, including extended cumulenes of the types RN=C=C=C=X, which themselves are used in the synthesis of many novel types of molecules, some of them of potential pharmaceutical interest (quinolone antibiotics; diazepines).
The research group has a world reputation in the field of carbene and nitrene chemistry, involving reactive intermediates with sextet carbon or nitrogen. These species are also very useful in synthesis, for example in the preparation of diazepines and diazepinones, a family of pharmaceutically interesting compounds. Numerous mechanistic studies and synthetic applications of ketenes have been carried out in our group.
Active collaborations are ongoing with scientists in Australia (UQ and CSIRO), China (Suzhou), France (Pau), Germany (Oldenburg), Japan (Hiroshima), Spain (Donostia - San Sebastian), and Portugal (Coimbra).
Availability
- Emeritus Professor Curt Wentrup is:
- Not available for supervision
- Media expert
Fields of research
Qualifications
- Doctor of Philosophy, Australian National University
- Doctor of Philosophy of Science (Advanced), University of Copenhagen
- Doctoral Diploma, Institution to be confirmed
- Australian Academy of Science, Australian Academy of Science
- Royal Australian Chemical Institute, Royal Australian Chemical Institute
Research interests
-
Organic, physical, and historical chemistry
Reactive intermediates, pyrolysis, photochemistry, reaction mechanism. History of science.
Research impacts
This research leads to the development of new pharmaceuticals, e.g. new antibiotics (quinolones and naphthyridones) and new leads towards a treatment for scizophrenia (diazepine molecules).
Chemical industry has used our pyrolysis techniques in specialized manufacturing processes.
Our analytical/spectroscopic work has led to cooperation with chemical and energy firms and agencies involved in forensic science, and our research has generated collaborations with many scientists at universities in Australia, Austria, Belgium, China, Denmark, France, Germany, Hungary, Japan, Portugal, Singapore, Switzerland, and USA.
Works
Search Professor Curt Wentrup’s works on UQ eSpace
1998
Journal Article
Ketenes from N-(2-pyridyl)amides. Isolation of methoxycarbonyl ketenes
Plug, C and Wentrup, C (1998). Ketenes from N-(2-pyridyl)amides. Isolation of methoxycarbonyl ketenes. Acta Chemica Scandinavica, 52 (5), 654-655. doi: 10.3891/acta.chem.scand.52-0654
1998
Journal Article
Retro-Ene Reactions in Acylallene Derivatives
Bibas H., Koch R. and Wentrup C. (1998). Retro-Ene Reactions in Acylallene Derivatives. Journal of Organic Chemistry, 63 (8), 2619-2626. doi: 10.1021/jo972137m
1998
Journal Article
Facile 1,3-shift of chlorine in a chlorocarbonylketene
Finnerty J., Andraos J., Yamamoto Y., Wong M.W. and Wentrup C. (1998). Facile 1,3-shift of chlorine in a chlorocarbonylketene. Journal of the American Chemical Society, 120 (8), 1701-1704. doi: 10.1021/ja973242g
1998
Journal Article
Carboxy(vinyl)ketene intermediates in the thermolysis of methylthio- and methoxy-substituted Meldrum's acid derivatives
Bibas, H, Kappe, CO, Wong, MW and Wentrup, C (1998). Carboxy(vinyl)ketene intermediates in the thermolysis of methylthio- and methoxy-substituted Meldrum's acid derivatives. Journal of the Chemical Society-Perkin Transactions 2, 29 (3), 493-498. doi: 10.1039/a708585k
1998
Journal Article
Generation of nitrile N-selenides, RC NSe, as neutrals and radical cations in the gas phase
Gerbaux, P, Flammang, R, Morkved, EH, Wong, MW and Wentrup, C (1998). Generation of nitrile N-selenides, RC NSe, as neutrals and radical cations in the gas phase. Tetrahedron Letters, 39 (7), 533-536. doi: 10.1016/S0040-4039(97)10228-3
1998
Journal Article
N-mesityl-C-acylketenimines: 1,5-sigmatropic shifts and electrocyclization to quinolines
Rao, VV. R., Fulloon, B. E., Bernhardt, P. V., Koch, R. and Wentrup, C. (1998). N-mesityl-C-acylketenimines: 1,5-sigmatropic shifts and electrocyclization to quinolines. Journal of Organic Chemistry, 63 (17), 5779-5786. doi: 10.1021/jo9722562
1997
Journal Article
Characterization of cyanogen N-oxide radical cation (NCCNO center dot+) in the gas phase by tandem mass spectrometry methodologies and ab initio calculations
Flammang, R, Barbieux-Flammang, M, Gerbaux, P, Wentrup, C and Wong, MW (1997). Characterization of cyanogen N-oxide radical cation (NCCNO center dot+) in the gas phase by tandem mass spectrometry methodologies and ab initio calculations. Bulletin Des Societes Chimiques Belges, 106 (9-10), 545-551.
1997
Journal Article
Generation of nitrile N-sulfide (RCNS) radical cations and neutrals via ion-molecule reactions: Tandem mass spectrometry and ab initio MO study
Gerbaux, P, VanHaverbeke, Y, Flammang, R, Wong, MW and Wentrup, C (1997). Generation of nitrile N-sulfide (RCNS) radical cations and neutrals via ion-molecule reactions: Tandem mass spectrometry and ab initio MO study. Journal of Physical Chemistry a, 101 (37), 6970-6975. doi: 10.1021/jp971170+
1997
Journal Article
Photochemistry of pyridyl azides and diazo ketones in matrix and in solution
Wentrup C., Reisinger A., Qiao G.G. and Visser P. (1997). Photochemistry of pyridyl azides and diazo ketones in matrix and in solution. Pure and Applied Chemistry, 69 (4), 847-850. doi: 10.1351/pac199769040847
1997
Journal Article
Nitrilimines: Evidence for the allenic structure in solution, experimental and ab initio studies of the barrier to racemization, and first diastereoselective [3+2]-cycloaddition
Faure, JL, Reau, R, Wong, MW, Koch, R, Wentrup, C and Bertrand, G (1997). Nitrilimines: Evidence for the allenic structure in solution, experimental and ab initio studies of the barrier to racemization, and first diastereoselective [3+2]-cycloaddition. Journal of the American Chemical Society, 119 (12), 2819-2824. doi: 10.1021/ja9637661
1997
Journal Article
Formation of thioketenes by thermal fragmentation of 1,2-dithiol-3-ones
Jorgensen T., Pedersen C.Th., Flammang R. and Wentrup C. (1997). Formation of thioketenes by thermal fragmentation of 1,2-dithiol-3-ones. Journal of the Chemical Society-Perkin Transactions 2 (2), 173-177. doi: 10.1039/a606411f
1997
Journal Article
The vinylketene-acylallene rearrangement: Theory and experiment
Bibas H., Wong M.W. and Wentrup C. (1997). The vinylketene-acylallene rearrangement: Theory and experiment. Chemistry - A European Journal, 3 (2), 237-248. doi: 10.1002/chem.19970030212
1996
Journal Article
Reactivity of carbenes and ketenes in low-temperature matrices. Carbene CO trapping, Wolff rearrangement, and ketene-pyridine ylide (zwitterion) observation
Visser P., Zuhse R., Wong M.W. and Wentrup C. (1996). Reactivity of carbenes and ketenes in low-temperature matrices. Carbene CO trapping, Wolff rearrangement, and ketene-pyridine ylide (zwitterion) observation. Journal of the American Chemical Society, 118 (50), 12598-12602. doi: 10.1021/ja962672o
1996
Journal Article
Synthesis of N-confused porphyrin analogues by β-azafulvenone tetramerization
Qiao G.G., Wong M.W. and Wentrup C. (1996). Synthesis of N-confused porphyrin analogues by β-azafulvenone tetramerization. Journal of Organic Chemistry, 61 (23), 8125-8131. doi: 10.1021/jo9609438
1996
Journal Article
Facile 1,3- and 1,5-chlorine migration
Koch R., Wong M.W. and Wentrup C. (1996). Facile 1,3- and 1,5-chlorine migration. Journal of Organic Chemistry, 61 (20), 6809-6813. doi: 10.1021/jo9740002
1996
Journal Article
Novel heterocumulenes: Bisiminopropadienes and linear ketenimines
Wolf, R, Stadtmuller, S, Wong, MW, BarbieuxFlammang, M, Flammang, R and Wentrup, C (1996). Novel heterocumulenes: Bisiminopropadienes and linear ketenimines. Chemistry-A European Journal, 2 (10), 1318-1329. doi: 10.1002/chem.19960021020
1996
Journal Article
Interconversions of phenylcarbene, cycloheptatetraene, fulvenallene, and benzocyclopropene. A theoretical study of the C7H6 energy surface
Wong, MW and Wentrup, C (1996). Interconversions of phenylcarbene, cycloheptatetraene, fulvenallene, and benzocyclopropene. A theoretical study of the C7H6 energy surface. Journal of Organic Chemistry, 61 (20), 7022-7029. doi: 10.1021/jo960806a
1996
Journal Article
Reactivity of ketenes in matrices. Direct observation of ketene-pyridine ylides
Qiao G.G., Andraos J. and Wentrup C. (1996). Reactivity of ketenes in matrices. Direct observation of ketene-pyridine ylides. Journal of the American Chemical Society, 118 (24), 5634-5638. doi: 10.1021/ja9607190
1996
Journal Article
Characterization of new cumulenes C(2)NX(2) (X=O or S): Tandem mass spectrometry and ab initio studies
Wong, MW, Wentrup, C, Morkved, EH and Flammang, R (1996). Characterization of new cumulenes C(2)NX(2) (X=O or S): Tandem mass spectrometry and ab initio studies. Journal of Physical Chemistry, 100 (25), 10536-10541. doi: 10.1021/jp960391x
1996
Journal Article
2-Pyridylnitrene-1,3-diazacyclohepta-1,2,4,6-tetraene rearrangements in the trifluoromethyl-2-pyridyl azide series
Evans, RA, Wong, MW and Wentrup, C (1996). 2-Pyridylnitrene-1,3-diazacyclohepta-1,2,4,6-tetraene rearrangements in the trifluoromethyl-2-pyridyl azide series. Journal of the American Chemical Society, 118 (17), 4009-4017. doi: 10.1021/ja9541645
Funding
Supervision
Availability
- Emeritus Professor Curt Wentrup is:
- Not available for supervision
Supervision history
Completed supervision
-
2006
Doctor Philosophy
SYNTHESES AND REACTIONS OF IMINOPROPADIENONES, SYDNONES AND OXAZINONES
Principal Advisor
Other advisors: Professor Craig Williams
-
2002
Doctor Philosophy
HETEROCYCLIC SYNTHESIS BASED ON IMINOPROPADIENONES
Principal Advisor
-
2002
Doctor Philosophy
SYNTHESIS AND CHARACTERISATION OF 1,3- and 1,4- DIAZEPINES AND DERIVATIVES
Principal Advisor
-
Doctor Philosophy
NITRENES REARRANGEMENTS: FORMATION OF REACTIVE INTERMEDIATES AND UNUSUAL MOLECULES
Principal Advisor
Other advisors: Professor Craig Williams
Media
Enquiries
Contact Emeritus Professor Curt Wentrup directly for media enquiries about:
- Organic reaction mechanisms
- Photochemistry
- Pyrolysis
- Reactive intermediates
Need help?
For help with finding experts, story ideas and media enquiries, contact our Media team: