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Emeritus Professor Curt Wentrup
Emeritus Professor

Curt Wentrup

Email: 
Phone: 
+61 7 336 53817

Overview

Background

Educated at the University of Copenhagen, Denmark, and the Australian National University, Canberra. Career at the Université de Lausanne, Switzerland, and the Universität Marburg, Germany. Professor and Chair of Organic Chemistry and Head of the Organic Chemistry Section, The University of Queensland from 1985. Emeritus professor from 2008. Chair of the National Committee for Chemistry of the Australian Academy of Science 2009-2014. Editor-in-Chief, Australian Journal of Chemistry 2008-15. Editor, Journal of Analytical and Applied Pyrolysis (Elsevier, IF 3.65) 2016-. Visiting Professor Université de Pau, France, 2011-19; Visiting Professor University of Kuwait 2014-18; Visiting Professor / Special Appointed Professor Hiroshima University 2014-18. Fellow of the Australian Academy of Science. Centenary Medal of the Australian Commonwealth 2003 for research in organic and physical chemistry. David Craig Medal of the Academy of Science 2014 for research in chemistry. JSPS Fellowship (Japan) 2014. Honorary doctorate, University of Pau, France, 2014. A.J. Birch Medal of the Royal Australian Chemical Institute (RACI) for ecellence in research in organic chemistry, 2014. Leighton Medal of the RACI 2018.

Research on Unusual Molecules and Reactive Intermediates: Synthesis and Reaction Mechanism. Heterocyclic chemistry. Pyrolysis reactions. Photochemistry

Research in the Wentrup group is concerned with the discovery of novel types of molecules with new and unusual bonding patterns. Such molecules are mostly highly reactive, and special methods are required both for their generation and for their detection. The group has developed these methods over many years and acquired world-class equipment for these purposes, including flash vacuum thermolysis apparatus, cryostats for matrix isolation of reaction products at cryogenic temperatures (down to 7 K), matrix and solution photochemistry equipment, infrared, UV and mass spectrometers, as well as modern computational facilities.

This research has resulted in the synthesis and characterization of many novel compounds, including extended cumulenes of the types RN=C=C=C=X, which themselves are used in the synthesis of many novel types of molecules, some of them of potential pharmaceutical interest (quinolone antibiotics; diazepines).

The research group has a world reputation in the field of carbene and nitrene chemistry, involving reactive intermediates with sextet carbon or nitrogen. These species are also very useful in synthesis, for example in the preparation of diazepines and diazepinones, a family of pharmaceutically interesting compounds. Numerous mechanistic studies and synthetic applications of ketenes have been carried out in our group.

Active collaborations are ongoing with scientists in Australia (UQ and CSIRO), China (Suzhou), France (Pau), Germany (Oldenburg), Japan (Hiroshima), Spain (Donostia - San Sebastian), and Portugal (Coimbra).

Availability

Emeritus Professor Curt Wentrup is:
Not available for supervision
Media expert

Qualifications

  • Doctor of Philosophy, Australian National University
  • Doctor of Philosophy of Science (Advanced), University of Copenhagen
  • Doctoral Diploma, Institution to be confirmed
  • Australian Academy of Science, Australian Academy of Science
  • Royal Australian Chemical Institute, Royal Australian Chemical Institute

Research interests

  • Organic, physical, and historical chemistry

    Reactive intermediates, pyrolysis, photochemistry, reaction mechanism. History of science.

Research impacts

This research leads to the development of new pharmaceuticals, e.g. new antibiotics (quinolones and naphthyridones) and new leads towards a treatment for scizophrenia (diazepine molecules).

Chemical industry has used our pyrolysis techniques in specialized manufacturing processes.

Our analytical/spectroscopic work has led to cooperation with chemical and energy firms and agencies involved in forensic science, and our research has generated collaborations with many scientists at universities in Australia, Austria, Belgium, China, Denmark, France, Germany, Hungary, Japan, Portugal, Singapore, Switzerland, and USA.

Works

Search Professor Curt Wentrup’s works on UQ eSpace

433 works between 1966 and 2024

241 - 260 of 433 works

1998

Journal Article

Ketenes from N-(2-pyridyl)amides. Isolation of methoxycarbonyl ketenes

Plug, C and Wentrup, C (1998). Ketenes from N-(2-pyridyl)amides. Isolation of methoxycarbonyl ketenes. Acta Chemica Scandinavica, 52 (5), 654-655. doi: 10.3891/acta.chem.scand.52-0654

Ketenes from N-(2-pyridyl)amides. Isolation of methoxycarbonyl ketenes

1998

Journal Article

Retro-Ene Reactions in Acylallene Derivatives

Bibas H., Koch R. and Wentrup C. (1998). Retro-Ene Reactions in Acylallene Derivatives. Journal of Organic Chemistry, 63 (8), 2619-2626. doi: 10.1021/jo972137m

Retro-Ene Reactions in Acylallene Derivatives

1998

Journal Article

Facile 1,3-shift of chlorine in a chlorocarbonylketene

Finnerty J., Andraos J., Yamamoto Y., Wong M.W. and Wentrup C. (1998). Facile 1,3-shift of chlorine in a chlorocarbonylketene. Journal of the American Chemical Society, 120 (8), 1701-1704. doi: 10.1021/ja973242g

Facile 1,3-shift of chlorine in a chlorocarbonylketene

1998

Journal Article

Carboxy(vinyl)ketene intermediates in the thermolysis of methylthio- and methoxy-substituted Meldrum's acid derivatives

Bibas, H, Kappe, CO, Wong, MW and Wentrup, C (1998). Carboxy(vinyl)ketene intermediates in the thermolysis of methylthio- and methoxy-substituted Meldrum's acid derivatives. Journal of the Chemical Society-Perkin Transactions 2, 29 (3), 493-498. doi: 10.1039/a708585k

Carboxy(vinyl)ketene intermediates in the thermolysis of methylthio- and methoxy-substituted Meldrum's acid derivatives

1998

Journal Article

Generation of nitrile N-selenides, RC NSe, as neutrals and radical cations in the gas phase

Gerbaux, P, Flammang, R, Morkved, EH, Wong, MW and Wentrup, C (1998). Generation of nitrile N-selenides, RC NSe, as neutrals and radical cations in the gas phase. Tetrahedron Letters, 39 (7), 533-536. doi: 10.1016/S0040-4039(97)10228-3

Generation of nitrile N-selenides, RC NSe, as neutrals and radical cations in the gas phase

1998

Journal Article

N-mesityl-C-acylketenimines: 1,5-sigmatropic shifts and electrocyclization to quinolines

Rao, VV. R., Fulloon, B. E., Bernhardt, P. V., Koch, R. and Wentrup, C. (1998). N-mesityl-C-acylketenimines: 1,5-sigmatropic shifts and electrocyclization to quinolines. Journal of Organic Chemistry, 63 (17), 5779-5786. doi: 10.1021/jo9722562

N-mesityl-C-acylketenimines: 1,5-sigmatropic shifts and electrocyclization to quinolines

1997

Journal Article

Characterization of cyanogen N-oxide radical cation (NCCNO center dot+) in the gas phase by tandem mass spectrometry methodologies and ab initio calculations

Flammang, R, Barbieux-Flammang, M, Gerbaux, P, Wentrup, C and Wong, MW (1997). Characterization of cyanogen N-oxide radical cation (NCCNO center dot+) in the gas phase by tandem mass spectrometry methodologies and ab initio calculations. Bulletin Des Societes Chimiques Belges, 106 (9-10), 545-551.

Characterization of cyanogen N-oxide radical cation (NCCNO center dot+) in the gas phase by tandem mass spectrometry methodologies and ab initio calculations

1997

Journal Article

Generation of nitrile N-sulfide (RCNS) radical cations and neutrals via ion-molecule reactions: Tandem mass spectrometry and ab initio MO study

Gerbaux, P, VanHaverbeke, Y, Flammang, R, Wong, MW and Wentrup, C (1997). Generation of nitrile N-sulfide (RCNS) radical cations and neutrals via ion-molecule reactions: Tandem mass spectrometry and ab initio MO study. Journal of Physical Chemistry a, 101 (37), 6970-6975. doi: 10.1021/jp971170+

Generation of nitrile N-sulfide (RCNS) radical cations and neutrals via ion-molecule reactions: Tandem mass spectrometry and ab initio MO study

1997

Journal Article

Photochemistry of pyridyl azides and diazo ketones in matrix and in solution

Wentrup C., Reisinger A., Qiao G.G. and Visser P. (1997). Photochemistry of pyridyl azides and diazo ketones in matrix and in solution. Pure and Applied Chemistry, 69 (4), 847-850. doi: 10.1351/pac199769040847

Photochemistry of pyridyl azides and diazo ketones in matrix and in solution

1997

Journal Article

Nitrilimines: Evidence for the allenic structure in solution, experimental and ab initio studies of the barrier to racemization, and first diastereoselective [3+2]-cycloaddition

Faure, JL, Reau, R, Wong, MW, Koch, R, Wentrup, C and Bertrand, G (1997). Nitrilimines: Evidence for the allenic structure in solution, experimental and ab initio studies of the barrier to racemization, and first diastereoselective [3+2]-cycloaddition. Journal of the American Chemical Society, 119 (12), 2819-2824. doi: 10.1021/ja9637661

Nitrilimines: Evidence for the allenic structure in solution, experimental and ab initio studies of the barrier to racemization, and first diastereoselective [3+2]-cycloaddition

1997

Journal Article

Formation of thioketenes by thermal fragmentation of 1,2-dithiol-3-ones

Jorgensen T., Pedersen C.Th., Flammang R. and Wentrup C. (1997). Formation of thioketenes by thermal fragmentation of 1,2-dithiol-3-ones. Journal of the Chemical Society-Perkin Transactions 2 (2), 173-177. doi: 10.1039/a606411f

Formation of thioketenes by thermal fragmentation of 1,2-dithiol-3-ones

1997

Journal Article

The vinylketene-acylallene rearrangement: Theory and experiment

Bibas H., Wong M.W. and Wentrup C. (1997). The vinylketene-acylallene rearrangement: Theory and experiment. Chemistry - A European Journal, 3 (2), 237-248. doi: 10.1002/chem.19970030212

The vinylketene-acylallene rearrangement: Theory and experiment

1996

Journal Article

Reactivity of carbenes and ketenes in low-temperature matrices. Carbene CO trapping, Wolff rearrangement, and ketene-pyridine ylide (zwitterion) observation

Visser P., Zuhse R., Wong M.W. and Wentrup C. (1996). Reactivity of carbenes and ketenes in low-temperature matrices. Carbene CO trapping, Wolff rearrangement, and ketene-pyridine ylide (zwitterion) observation. Journal of the American Chemical Society, 118 (50), 12598-12602. doi: 10.1021/ja962672o

Reactivity of carbenes and ketenes in low-temperature matrices. Carbene CO trapping, Wolff rearrangement, and ketene-pyridine ylide (zwitterion) observation

1996

Journal Article

Synthesis of N-confused porphyrin analogues by β-azafulvenone tetramerization

Qiao G.G., Wong M.W. and Wentrup C. (1996). Synthesis of N-confused porphyrin analogues by β-azafulvenone tetramerization. Journal of Organic Chemistry, 61 (23), 8125-8131. doi: 10.1021/jo9609438

Synthesis of N-confused porphyrin analogues by β-azafulvenone tetramerization

1996

Journal Article

Facile 1,3- and 1,5-chlorine migration

Koch R., Wong M.W. and Wentrup C. (1996). Facile 1,3- and 1,5-chlorine migration. Journal of Organic Chemistry, 61 (20), 6809-6813. doi: 10.1021/jo9740002

Facile 1,3- and 1,5-chlorine migration

1996

Journal Article

Novel heterocumulenes: Bisiminopropadienes and linear ketenimines

Wolf, R, Stadtmuller, S, Wong, MW, BarbieuxFlammang, M, Flammang, R and Wentrup, C (1996). Novel heterocumulenes: Bisiminopropadienes and linear ketenimines. Chemistry-A European Journal, 2 (10), 1318-1329. doi: 10.1002/chem.19960021020

Novel heterocumulenes: Bisiminopropadienes and linear ketenimines

1996

Journal Article

Interconversions of phenylcarbene, cycloheptatetraene, fulvenallene, and benzocyclopropene. A theoretical study of the C7H6 energy surface

Wong, MW and Wentrup, C (1996). Interconversions of phenylcarbene, cycloheptatetraene, fulvenallene, and benzocyclopropene. A theoretical study of the C7H6 energy surface. Journal of Organic Chemistry, 61 (20), 7022-7029. doi: 10.1021/jo960806a

Interconversions of phenylcarbene, cycloheptatetraene, fulvenallene, and benzocyclopropene. A theoretical study of the C7H6 energy surface

1996

Journal Article

Reactivity of ketenes in matrices. Direct observation of ketene-pyridine ylides

Qiao G.G., Andraos J. and Wentrup C. (1996). Reactivity of ketenes in matrices. Direct observation of ketene-pyridine ylides. Journal of the American Chemical Society, 118 (24), 5634-5638. doi: 10.1021/ja9607190

Reactivity of ketenes in matrices. Direct observation of ketene-pyridine ylides

1996

Journal Article

Characterization of new cumulenes C(2)NX(2) (X=O or S): Tandem mass spectrometry and ab initio studies

Wong, MW, Wentrup, C, Morkved, EH and Flammang, R (1996). Characterization of new cumulenes C(2)NX(2) (X=O or S): Tandem mass spectrometry and ab initio studies. Journal of Physical Chemistry, 100 (25), 10536-10541. doi: 10.1021/jp960391x

Characterization of new cumulenes C(2)NX(2) (X=O or S): Tandem mass spectrometry and ab initio studies

1996

Journal Article

2-Pyridylnitrene-1,3-diazacyclohepta-1,2,4,6-tetraene rearrangements in the trifluoromethyl-2-pyridyl azide series

Evans, RA, Wong, MW and Wentrup, C (1996). 2-Pyridylnitrene-1,3-diazacyclohepta-1,2,4,6-tetraene rearrangements in the trifluoromethyl-2-pyridyl azide series. Journal of the American Chemical Society, 118 (17), 4009-4017. doi: 10.1021/ja9541645

2-Pyridylnitrene-1,3-diazacyclohepta-1,2,4,6-tetraene rearrangements in the trifluoromethyl-2-pyridyl azide series

Funding

Past funding

  • 2012 - 2013
    Heron Island Conference on reactive intermediate and unusual molecules
    Ian Potter Foundation
    Open grant
  • 2010
    UQ Travel Awards Category 1, Fabian Borget
    UQ Travel Grants Scheme
    Open grant
  • 2007 - 2008
    An X-Ray Diffraction Facility for Molecular Structure Determination
    ARC Linkage Infrastructure, Equipment and Facilities
    Open grant
  • 2007 - 2009
    Reactive intermediates and microwave-assisted organic reactions
    ARC Discovery Projects
    Open grant
  • 2007
    Research in pre-biotic chemistry
    UQ Travel Grants Scheme
    Open grant
  • 2004
    Research conference grant for Prof Josef Michl, University of Colorado, Boulder, to attend Heron Island Conference on reactive intermediates and unusual molecules, 17-23 July 2004
    Potter Foundation
    Open grant
  • 2004 - 2006
    New mechanisms and methods in carbene and nitrene chemistry
    ARC Discovery Projects
    Open grant
  • 2003 - 2005
    Bimolecular chemistry at very low temperature
    ARC Linkage International
    Open grant
  • 2002
    To expand work on cryogenic matrix isolation research.
    UQ Travel Grants Scheme
    Open grant
  • 2001 - 2003
    Chemistry of Iminopropadienones and Related Compounds.
    ARC Australian Research Council (Large grants)
    Open grant
  • 2000
    Novel approaches to heterocyclic synthesis.
    ARC Australian Research Council (Small grants)
    Open grant
  • 1997
    Brisbane Advanced Mass Spectrometry Facility
    Research Infrastructure (Equip & Fac) Program
    Open grant
  • 1997
    Synthesis of 1,3-diazepines
    ARC Australian Research Council (Small grants)
    Open grant
  • 1996 - 1997
    International Network in Advanced Techniques of Applied Molecular Science
    Quality Funds Round 3
    Open grant
  • 1996
    Pulsed pyrolysis
    ARC Australian Research Council (Small grants)
    Open grant

Supervision

Availability

Emeritus Professor Curt Wentrup is:
Not available for supervision

Supervision history

Completed supervision

  • 2006

    Doctor Philosophy

    SYNTHESES AND REACTIONS OF IMINOPROPADIENONES, SYDNONES AND OXAZINONES

    Principal Advisor

    Other advisors: Professor Craig Williams

  • 2002

    Doctor Philosophy

    HETEROCYCLIC SYNTHESIS BASED ON IMINOPROPADIENONES

    Principal Advisor

  • 2002

    Doctor Philosophy

    SYNTHESIS AND CHARACTERISATION OF 1,3- and 1,4- DIAZEPINES AND DERIVATIVES

    Principal Advisor

  • Doctor Philosophy

    NITRENES REARRANGEMENTS: FORMATION OF REACTIVE INTERMEDIATES AND UNUSUAL MOLECULES

    Principal Advisor

    Other advisors: Professor Craig Williams

Media

Enquiries

Contact Emeritus Professor Curt Wentrup directly for media enquiries about:

  • Organic reaction mechanisms
  • Photochemistry
  • Pyrolysis
  • Reactive intermediates

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