
Overview
Background
Educated at the University of Copenhagen, Denmark, and the Australian National University, Canberra. Career at the Université de Lausanne, Switzerland, and the Universität Marburg, Germany. Professor and Chair of Organic Chemistry and Head of the Organic Chemistry Section, The University of Queensland from 1985. Emeritus professor from 2008. Chair of the National Committee for Chemistry of the Australian Academy of Science 2009-2014. Editor-in-Chief, Australian Journal of Chemistry 2008-15. Editor, Journal of Analytical and Applied Pyrolysis (Elsevier, IF 3.65) 2016-. Visiting Professor Université de Pau, France, 2011-19; Visiting Professor University of Kuwait 2014-18; Visiting Professor / Special Appointed Professor Hiroshima University 2014-18. Fellow of the Australian Academy of Science. Centenary Medal of the Australian Commonwealth 2003 for research in organic and physical chemistry. David Craig Medal of the Academy of Science 2014 for research in chemistry. JSPS Fellowship (Japan) 2014. Honorary doctorate, University of Pau, France, 2014. A.J. Birch Medal of the Royal Australian Chemical Institute (RACI) for ecellence in research in organic chemistry, 2014. Leighton Medal of the RACI 2018.
Research on Unusual Molecules and Reactive Intermediates: Synthesis and Reaction Mechanism. Heterocyclic chemistry. Pyrolysis reactions. Photochemistry
Research in the Wentrup group is concerned with the discovery of novel types of molecules with new and unusual bonding patterns. Such molecules are mostly highly reactive, and special methods are required both for their generation and for their detection. The group has developed these methods over many years and acquired world-class equipment for these purposes, including flash vacuum thermolysis apparatus, cryostats for matrix isolation of reaction products at cryogenic temperatures (down to 7 K), matrix and solution photochemistry equipment, infrared, UV and mass spectrometers, as well as modern computational facilities.
This research has resulted in the synthesis and characterization of many novel compounds, including extended cumulenes of the types RN=C=C=C=X, which themselves are used in the synthesis of many novel types of molecules, some of them of potential pharmaceutical interest (quinolone antibiotics; diazepines).
The research group has a world reputation in the field of carbene and nitrene chemistry, involving reactive intermediates with sextet carbon or nitrogen. These species are also very useful in synthesis, for example in the preparation of diazepines and diazepinones, a family of pharmaceutically interesting compounds. Numerous mechanistic studies and synthetic applications of ketenes have been carried out in our group.
Active collaborations are ongoing with scientists in Australia (UQ and CSIRO), China (Suzhou), France (Pau), Germany (Oldenburg), Japan (Hiroshima), Spain (Donostia - San Sebastian), and Portugal (Coimbra).
Availability
- Emeritus Professor Curt Wentrup is:
- Not available for supervision
- Media expert
Fields of research
Qualifications
- Doctor of Philosophy, Australian National University
- Doctor of Philosophy of Science (Advanced), University of Copenhagen
- Doctoral Diploma, Institution to be confirmed
- Australian Academy of Science, Australian Academy of Science
- Royal Australian Chemical Institute, Royal Australian Chemical Institute
Research interests
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Organic, physical, and historical chemistry
Reactive intermediates, pyrolysis, photochemistry, reaction mechanism. History of science.
Research impacts
This research leads to the development of new pharmaceuticals, e.g. new antibiotics (quinolones and naphthyridones) and new leads towards a treatment for scizophrenia (diazepine molecules).
Chemical industry has used our pyrolysis techniques in specialized manufacturing processes.
Our analytical/spectroscopic work has led to cooperation with chemical and energy firms and agencies involved in forensic science, and our research has generated collaborations with many scientists at universities in Australia, Austria, Belgium, China, Denmark, France, Germany, Hungary, Japan, Portugal, Singapore, Switzerland, and USA.
Works
Search Professor Curt Wentrup’s works on UQ eSpace
2004
Journal Article
Facile ketene-ketene and ketene-ketenimine rearrangements: A study of the 1,3-migration of alpha-substituents interconverting alpha-imidoylketenes and alpha-oxoketenimines, a pseudopericyclic reaction
Finnerty, J. J. and Wentrup, C. (2004). Facile ketene-ketene and ketene-ketenimine rearrangements: A study of the 1,3-migration of alpha-substituents interconverting alpha-imidoylketenes and alpha-oxoketenimines, a pseudopericyclic reaction. Journal of Organic Chemistry, 69 (6), 1909-1918. doi: 10.1021/jo035419x
2004
Journal Article
Imidoylketene dimerization and rearrangement
George, L., Bernhardt, P. V., Netsch, K. P. and Wentrup, C. (2004). Imidoylketene dimerization and rearrangement. Organic & Biomolecular Chemistry, 2 (23), 3518-3523. doi: 10.1039/b412530d
2004
Journal Article
The rearrangements of naphthyinitrenes: UV/Vis and IR spectra of azirines, cyclic ketenimines, and cyclic nitrile ylides
Maltsev, A., Bally, T., Tsao, M. L., Platz, M. S., Kuhn, A., Vosswinkel, M. and Wentrup, C. (2004). The rearrangements of naphthyinitrenes: UV/Vis and IR spectra of azirines, cyclic ketenimines, and cyclic nitrile ylides. Journal of The American Chemical Society, 126 (1), 237-249. doi: 10.1021/ja038458z
2003
Journal Article
Synthesis and complexation properties of some novel lariat-crown ethers
Smounig, Ralf, Kappe, C. Oliver, Wentrup, Curt and Kollenz, Gert (2003). Synthesis and complexation properties of some novel lariat-crown ethers. Monatshefte Fur Chemie, 134 (4), 509-518. doi: 10.1007/s00706-002-0547-y
2003
Conference Publication
Methoxy(2-pyridyl)ketene
Andersen, Heidi Gade, Bednarek, Pawel and Wentrup, Curt (2003). Methoxy(2-pyridyl)ketene. Chichester, UK: John Wiley. doi: 10.1002/poc.628
2003
Journal Article
N-aminopyrroledione-hydrazonoketene-pyrazolium oxide-pyrazolone rearrangements and pyrazolone tautomerism
Ebner, S., Wallfisch, B., Andraos, J., Aitbaev, I., Kiselewsky, M., Bernhardt, P. V., Kollenz, G. and Wentrup, C. (2003). N-aminopyrroledione-hydrazonoketene-pyrazolium oxide-pyrazolone rearrangements and pyrazolone tautomerism. Organic & Biomolecular Chemistry, 1 (14), 2550-2555. doi: 10.1039/b304070d
2003
Journal Article
3-pyridylcarbene and 3-pyridylnitrene: Ring opening to nitrile ylides
Bednarek, P. and Wentrup, C. (2003). 3-pyridylcarbene and 3-pyridylnitrene: Ring opening to nitrile ylides. Journal of The American Chemical Society, 125 (30), 9083-9089. doi: 10.1021/ja035632a
2003
Journal Article
2-quinolyl- and 1-isoquinolylnitrenes: Ring expansion and ring opening in heteroarylnitrenes
Addicott, Chris, Reisinger, Ales and Wentrup, Curt (2003). 2-quinolyl- and 1-isoquinolylnitrenes: Ring expansion and ring opening in heteroarylnitrenes. Journal of Organic Chemistry, 68 (4), 1470-1474. doi: 10.1021/jo026439m
2003
Journal Article
Synthesis and host-abilities of some new corands bearing uncommon chiral spacer units
Heilmayer, W., Wallfisch, B., Kappe, C. O., Wentrup, C., Gloe, K. and Kollenz, G. (2003). Synthesis and host-abilities of some new corands bearing uncommon chiral spacer units. Supramolecular Chemistry, 15 (5), 375-383. doi: 10.1080/10610277031000108848
2002
Journal Article
A theoretical study of the origin of rotational barriers in push-pull ethylenes
Alkorta, I., Wentrup, C. and Elguero, J. (2002). A theoretical study of the origin of rotational barriers in push-pull ethylenes. Journal of Molecular Structure-theochem, 585 (1-3), 27-34. doi: 10.1016/S0166-1280(02)00036-2
2002
Journal Article
Linear ketenimines. Variable structures of C,C-dicyanoketenimines and C,C-bis-sulfonylketenimines
Finnerty, Justin, Mitschke, Ullrich and Wentrup, Curt (2002). Linear ketenimines. Variable structures of C,C-dicyanoketenimines and C,C-bis-sulfonylketenimines. Journal of Organic Chemistry, 67 (4), 1084-1092. doi: 10.1021/jo010398x
2002
Journal Article
2-pyrazinylnitrene and 4-pyrimidylnitrene. Ring expansion to 1,3,5-triazacyclohepta-1,2,4,6-tetraene and ring opening to (2-isocyanovinyl)carbodiimide
Addicott, C., Wong, M. W. and Wentrup, C. (2002). 2-pyrazinylnitrene and 4-pyrimidylnitrene. Ring expansion to 1,3,5-triazacyclohepta-1,2,4,6-tetraene and ring opening to (2-isocyanovinyl)carbodiimide. Journal of Organic Chemistry, 67 (24), 8538-8546. doi: 10.1021/jo0256991
2002
Journal Article
2,6,,9-trioxabicyclo[3.3.1]nona-3,7-dienes and 2,4,6,8-tetraoxaadamantanes: Novel chiral spacer units in macrocyclic polyethers
Wallfisch, Bianca C., Egger, Tamara, Heilmayer, Werner, Kappe, C. Oliver, Wentrup, Curt, Gloe, Karsten, Belaj, Ferdinand, Klintschar, Gerd and Kollenz, Gert (2002). 2,6,,9-trioxabicyclo[3.3.1]nona-3,7-dienes and 2,4,6,8-tetraoxaadamantanes: Novel chiral spacer units in macrocyclic polyethers. Supramolecular Chemistry, 14 (5), 383-396. doi: 10.1080/1061027021000003430
2002
Journal Article
Quinolizine-2,4-diones by reversible dimerisation 2-pyridylketenes
Plug, C., Kuhn, A. and Wentrup, C. (2002). Quinolizine-2,4-diones by reversible dimerisation 2-pyridylketenes. Journal of the Chemical Society Perkin Transactions I, 2 (11), 1366-1368. doi: 10.1039/b202523j
2002
Journal Article
Carbene and nitrene rearrangements: A theoretical study of cyclic allenes and carbenes, carbodiimides, and azirines
Kuhn, A., Vosswinkel, M. and Wentrup, C. (2002). Carbene and nitrene rearrangements: A theoretical study of cyclic allenes and carbenes, carbodiimides, and azirines. Journal of Organic Chemistry, 67 (25), 9023-9030. doi: 10.1021/jo0258756
2002
Journal Article
2-cyano(2-pyridyl)ketene
Plug, C., Ye, Y., Kuhn, A. and Wentrup, C. (2002). 2-cyano(2-pyridyl)ketene. European Journal of Organic Chemistry, 2002 (16), 2683-2685. doi: 10.1002/1099-0690(200208)2002:163.0.CO;2-J
2002
Journal Article
Synthesis and chemical reactivity of methoxycarbonyl-1,3-dioxinyl(pivaloyl)ketene - a persistent a-oxoketene
Wallfisch, B., Belaj, F., Wentrup, C., Kappe, O. and Kollenz, G. (2002). Synthesis and chemical reactivity of methoxycarbonyl-1,3-dioxinyl(pivaloyl)ketene - a persistent a-oxoketene. Journal of the Chemical Society Perkin Transactions I (5), 599-605.
2002
Journal Article
Chemistry of stable iminopropadienones, RN=C=C=C=O
Bibas, H., Moloney, D. W. J., Neumann, R., Shtaiwi, M., Bernhardt, P. V. and Wentrup, C. (2002). Chemistry of stable iminopropadienones, RN=C=C=C=O. Journal of Organic Chemistry, 67 (8), 2619-2631. doi: 10.1021/jo0110552
2002
Journal Article
Synthesis and chemical reactivity of methoxycarbonyl-1,3-dioxinyl(pivaloyl)ketene - a persistent alpha-oxoketene
Wallfisch, B. C., Belaj, F., Wentrup, C., Kappe, C. O. and Kollenz, G. (2002). Synthesis and chemical reactivity of methoxycarbonyl-1,3-dioxinyl(pivaloyl)ketene - a persistent alpha-oxoketene. Journal of The Chemical Society-perkin Transactions 1, 2 (5), 599-605. doi: 10.1039/b111143d
2002
Journal Article
Iminopropadienones from dioxanediones, isoxazolopyrimidinones, pyridopyrimidinones, and pyridopyrimidinium olates
Shtaiwi, M. and Wentrup, C. (2002). Iminopropadienones from dioxanediones, isoxazolopyrimidinones, pyridopyrimidinones, and pyridopyrimidinium olates. Journal of Organic Chemistry, 67 (24), 8558-8565. doi: 10.1021/jo026275+
Funding
Supervision
Availability
- Emeritus Professor Curt Wentrup is:
- Not available for supervision
Supervision history
Completed supervision
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2006
Doctor Philosophy
SYNTHESES AND REACTIONS OF IMINOPROPADIENONES, SYDNONES AND OXAZINONES
Principal Advisor
Other advisors: Professor Craig Williams
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2002
Doctor Philosophy
HETEROCYCLIC SYNTHESIS BASED ON IMINOPROPADIENONES
Principal Advisor
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2002
Doctor Philosophy
SYNTHESIS AND CHARACTERISATION OF 1,3- and 1,4- DIAZEPINES AND DERIVATIVES
Principal Advisor
-
Doctor Philosophy
NITRENES REARRANGEMENTS: FORMATION OF REACTIVE INTERMEDIATES AND UNUSUAL MOLECULES
Principal Advisor
Other advisors: Professor Craig Williams
Media
Enquiries
Contact Emeritus Professor Curt Wentrup directly for media enquiries about:
- Organic reaction mechanisms
- Photochemistry
- Pyrolysis
- Reactive intermediates
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