
Overview
Background
Educated at the University of Copenhagen, Denmark, and the Australian National University, Canberra. Career at the Université de Lausanne, Switzerland, and the Universität Marburg, Germany. Professor and Chair of Organic Chemistry and Head of the Organic Chemistry Section, The University of Queensland from 1985. Emeritus professor from 2008. Chair of the National Committee for Chemistry of the Australian Academy of Science 2009-2014. Editor-in-Chief, Australian Journal of Chemistry 2008-15. Editor, Journal of Analytical and Applied Pyrolysis (Elsevier, IF 3.65) 2016-. Visiting Professor Université de Pau, France, 2011-19; Visiting Professor University of Kuwait 2014-18; Visiting Professor / Special Appointed Professor Hiroshima University 2014-18. Fellow of the Australian Academy of Science. Centenary Medal of the Australian Commonwealth 2003 for research in organic and physical chemistry. David Craig Medal of the Academy of Science 2014 for research in chemistry. JSPS Fellowship (Japan) 2014. Honorary doctorate, University of Pau, France, 2014. A.J. Birch Medal of the Royal Australian Chemical Institute (RACI) for ecellence in research in organic chemistry, 2014. Leighton Medal of the RACI 2018.
Research on Unusual Molecules and Reactive Intermediates: Synthesis and Reaction Mechanism. Heterocyclic chemistry. Pyrolysis reactions. Photochemistry
Research in the Wentrup group is concerned with the discovery of novel types of molecules with new and unusual bonding patterns. Such molecules are mostly highly reactive, and special methods are required both for their generation and for their detection. The group has developed these methods over many years and acquired world-class equipment for these purposes, including flash vacuum thermolysis apparatus, cryostats for matrix isolation of reaction products at cryogenic temperatures (down to 7 K), matrix and solution photochemistry equipment, infrared, UV and mass spectrometers, as well as modern computational facilities.
This research has resulted in the synthesis and characterization of many novel compounds, including extended cumulenes of the types RN=C=C=C=X, which themselves are used in the synthesis of many novel types of molecules, some of them of potential pharmaceutical interest (quinolone antibiotics; diazepines).
The research group has a world reputation in the field of carbene and nitrene chemistry, involving reactive intermediates with sextet carbon or nitrogen. These species are also very useful in synthesis, for example in the preparation of diazepines and diazepinones, a family of pharmaceutically interesting compounds. Numerous mechanistic studies and synthetic applications of ketenes have been carried out in our group.
Active collaborations are ongoing with scientists in Australia (UQ and CSIRO), China (Suzhou), France (Pau), Germany (Oldenburg), Japan (Hiroshima), Spain (Donostia - San Sebastian), and Portugal (Coimbra).
Availability
- Emeritus Professor Curt Wentrup is:
- Not available for supervision
- Media expert
Fields of research
Qualifications
- Doctor of Philosophy, Australian National University
- Doctor of Philosophy of Science (Advanced), University of Copenhagen
- Doctoral Diploma, Institution to be confirmed
- Australian Academy of Science, Australian Academy of Science
- Royal Australian Chemical Institute, Royal Australian Chemical Institute
Research interests
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Organic, physical, and historical chemistry
Reactive intermediates, pyrolysis, photochemistry, reaction mechanism. History of science.
Research impacts
This research leads to the development of new pharmaceuticals, e.g. new antibiotics (quinolones and naphthyridones) and new leads towards a treatment for scizophrenia (diazepine molecules).
Chemical industry has used our pyrolysis techniques in specialized manufacturing processes.
Our analytical/spectroscopic work has led to cooperation with chemical and energy firms and agencies involved in forensic science, and our research has generated collaborations with many scientists at universities in Australia, Austria, Belgium, China, Denmark, France, Germany, Hungary, Japan, Portugal, Singapore, Switzerland, and USA.
Works
Search Professor Curt Wentrup’s works on UQ eSpace
1992
Journal Article
Characterization of Iminopropadienone Ions and Neutrals in a Tandem Mass-Spectrometer
Flammang, R, Laurent, S, Flammangbarbieux, M and Wentrup, C (1992). Characterization of Iminopropadienone Ions and Neutrals in a Tandem Mass-Spectrometer. Rapid Communications in Mass Spectrometry, 6 (11), 667-670. doi: 10.1002/rcm.1290061108
1992
Journal Article
Flash Vacuum Pyrolysis of Tert-Butyl Beta-Ketoesters - Sterically Protected Alpha-Oxoketenes
Leungtoung, R and Wentrup, C (1992). Flash Vacuum Pyrolysis of Tert-Butyl Beta-Ketoesters - Sterically Protected Alpha-Oxoketenes. Tetrahedron, 48 (36), 7641-7654. doi: 10.1016/S0040-4020(01)90376-X
1992
Journal Article
A NOVEL AND CONVENIENT APPROACH TO FUNCTIONALIZED 2,6,9-TRIOXABICYCLO[3.3.1]NONA-3,7-DIENES (BRIDGED BIS-DIOXINES)
KAPPE, CO, FARBER, G, WENTRUP, C and KOLLENZ, G (1992). A NOVEL AND CONVENIENT APPROACH TO FUNCTIONALIZED 2,6,9-TRIOXABICYCLO[3.3.1]NONA-3,7-DIENES (BRIDGED BIS-DIOXINES). Tetrahedron Letters, 33 (32), 4553-4556. doi: 10.1016/S0040-4039(00)61310-2
1992
Journal Article
DIRECT OBSERVATION OF BENZOYLKETENES
ANDREICHIKOV, YS, KOLLENZ, G, KAPPE, CO, LEUNGTOUNG, R and WENTRUP, C (1992). DIRECT OBSERVATION OF BENZOYLKETENES. Acta Chemica Scandinavica, 46 (7), 683-685. doi: 10.3891/acta.chem.scand.46-0683
1992
Journal Article
HCN DIMERS - PHOTOELECTRON-SPECTRUM OF IMINOACETONITRILE
EVANS, RA, LACOMBE, SM, SIMON, MJ, PFISTERGUILLOUZO, G and WENTRUP, C (1992). HCN DIMERS - PHOTOELECTRON-SPECTRUM OF IMINOACETONITRILE. Journal of Physical Chemistry, 96 (12), 4801-4804. doi: 10.1021/j100191a015
1992
Journal Article
An ab Initio Study of a Retro-Wolff Rearrangement: From Diazafulvenone to Cyanovinyl Isocyanate without a Singlet α-Oxocarbene Intermediate
Nguyen M.T., Hajnal M.R., Tae-Kyu H., Vanquickenborne L.G. and Wentrup C. (1992). An ab Initio Study of a Retro-Wolff Rearrangement: From Diazafulvenone to Cyanovinyl Isocyanate without a Singlet α-Oxocarbene Intermediate. Journal of the American Chemical Society, 114 (11), 4387-4390. doi: 10.1021/ja00037a054
1992
Journal Article
Electron-Impact and Chemical Ionization Mass-Spectrometry of Heterocumulenes Produced by Flash Vacuum Pyrolysis
Brown, J, Flammang, R, Govaert, Y, Plisnier, M, Wentrup, C and Vanhaverbeke, Y (1992). Electron-Impact and Chemical Ionization Mass-Spectrometry of Heterocumulenes Produced by Flash Vacuum Pyrolysis. Rapid Communications in Mass Spectrometry, 6 (4), 249-253. doi: 10.1002/rcm.1290060405
1992
Journal Article
INFRARED-SPECTRUM OF DINITROGEN SULFIDE
KAMBOURIS, P, HA, TK and WENTRUP, C (1992). INFRARED-SPECTRUM OF DINITROGEN SULFIDE. Journal of Physical Chemistry, 96 (5), 2065-2068. doi: 10.1021/j100184a010
1992
Journal Article
Methyleneketene Imidoylketene Oxoketenimine Rearrangements
Kappe, CO, Kollenz, G, Regis, LT and Wentrup, C (1992). Methyleneketene Imidoylketene Oxoketenimine Rearrangements. Journal of the Chemical Society-Chemical Communications (6), 487-488. doi: 10.1039/c39920000487
1992
Journal Article
Imidoylketene Azetin-2-One Oxoketenimine Rearrangement
Kappe, CO, Kollenz, G, Netsch, KP, Regis, LT and Wentrup, C (1992). Imidoylketene Azetin-2-One Oxoketenimine Rearrangement. Journal of the Chemical Society-Chemical Communications (6), 488-490. doi: 10.1039/c39920000488
1992
Journal Article
A Nitroketene to Nitrile Oxide Transformation
Kappe, CO, Kollenz, G and Wentrup, C (1992). A Nitroketene to Nitrile Oxide Transformation. Journal of the Chemical Society-Chemical Communications, 23 (6), 485-486. doi: 10.1039/c39920000485
1992
Journal Article
UNIMOLECULAR CHEMISTRY OF OXAZOLE AND ISOXAZOLE RADICAL CATIONS IN THE GAS-PHASE - COMBINED EXPERIMENTAL AND MOLECULAR-ORBITAL STUDY
FLAMMANG, R, PLISNIER, M, BOUCHOUX, G, HOPPILLIARD, Y, HUMBERT, S and WENTRUP, C (1992). UNIMOLECULAR CHEMISTRY OF OXAZOLE AND ISOXAZOLE RADICAL CATIONS IN THE GAS-PHASE - COMBINED EXPERIMENTAL AND MOLECULAR-ORBITAL STUDY. Organic Mass Spectrometry, 27 (3), 317-325. doi: 10.1002/oms.1210270326
1992
Journal Article
Direct observation of α-oxo ketenes from the photolysis of α-diazo β-diketones
Leung-Toung R. and Wentrup C. (1992). Direct observation of α-oxo ketenes from the photolysis of α-diazo β-diketones. Journal of Organic Chemistry, 57 (18), 4850-4858. doi: 10.1021/jo00044a019
1992
Journal Article
Iminopropadienones, RN=C=C=C=O: Syntheses and reactions
Mosandl T., Kappe C.O., Flammang R. and Wentrup C. (1992). Iminopropadienones, RN=C=C=C=O: Syntheses and reactions. Journal of the Chemical Society-Chemical Communications, 24 (21), 1571-1573. doi: 10.1039/C39920001571
1992
Journal Article
Trifluoromethyl-substituted dehydrodiazepines and cyanopyrroles from azido-/tetrazolo-pyridines
Evans R.A. and Wentrup C. (1992). Trifluoromethyl-substituted dehydrodiazepines and cyanopyrroles from azido-/tetrazolo-pyridines. Journal of the Chemical Society, Chemical Communications, 23 (15), 1062-1064. doi: 10.1039/C39920001062
1991
Journal Article
HCN DIMERS - IMINOACETONITRILE AND N-CYANOMETHANIMINE
EVANS, RA, LORENCAK, P, HA, TK and WENTRUP, C (1991). HCN DIMERS - IMINOACETONITRILE AND N-CYANOMETHANIMINE. Journal of the American Chemical Society, 113 (19), 7261-7276. doi: 10.1021/ja00019a026
1991
Journal Article
N-SULFIDES - DINITROGEN SULFIDE, THIOFULMINIC ACID, AND NITRILE SULFIDES
WENTRUP, C and KAMBOURIS, P (1991). N-SULFIDES - DINITROGEN SULFIDE, THIOFULMINIC ACID, AND NITRILE SULFIDES. Chemical Reviews, 91 (3), 363-373. doi: 10.1021/cr00003a004
1991
Journal Article
THIOFULMINIC ACID (H-C=N-]S) AND NITRILE SULFIDES (R-C=N-]S) IN THE GAS-PHASE
KAMBOURIS, P, PLISNIER, M, FLAMMANG, R, TERLOUW, JK and WENTRUP, C (1991). THIOFULMINIC ACID (H-C=N-]S) AND NITRILE SULFIDES (R-C=N-]S) IN THE GAS-PHASE. Tetrahedron Letters, 32 (11), 1487-1490. doi: 10.1016/0040-4039(91)80365-D
1991
Journal Article
SYNTHESIS OF ALPHA-CYANO CARBONYL-COMPOUNDS BY FLASH VACUUM THERMOLYSIS OF (ALKYLAMINO)METHYLENE DERIVATIVES OF MELDRUMS ACID - EVIDENCE FOR FACILE 1,3-SHIFTS OF ALKYLAMINO AND ALKYLTHIO GROUPS IN IMIDOYLKETENE INTERMEDIATES
BENCHEIKH, A, CHUCHE, J, MANISSE, N, POMMELET, JC, NETSCH, KP, LORENCAK, P and WENTRUP, C (1991). SYNTHESIS OF ALPHA-CYANO CARBONYL-COMPOUNDS BY FLASH VACUUM THERMOLYSIS OF (ALKYLAMINO)METHYLENE DERIVATIVES OF MELDRUMS ACID - EVIDENCE FOR FACILE 1,3-SHIFTS OF ALKYLAMINO AND ALKYLTHIO GROUPS IN IMIDOYLKETENE INTERMEDIATES. Journal of Organic Chemistry, 56 (3), 970-975. doi: 10.1021/jo00003a014
1991
Journal Article
Direct observation of α-oxo ketenes formed from 1,3-dioxin-4-ones and the enols of β-keto esters
Freiermuth B. and Wentrup C. (1991). Direct observation of α-oxo ketenes formed from 1,3-dioxin-4-ones and the enols of β-keto esters. Journal of Organic Chemistry, 56 (7), 2286-2289. doi: 10.1021/jo00007a008
Funding
Supervision
Availability
- Emeritus Professor Curt Wentrup is:
- Not available for supervision
Supervision history
Completed supervision
-
2006
Doctor Philosophy
SYNTHESES AND REACTIONS OF IMINOPROPADIENONES, SYDNONES AND OXAZINONES
Principal Advisor
Other advisors: Professor Craig Williams
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2002
Doctor Philosophy
HETEROCYCLIC SYNTHESIS BASED ON IMINOPROPADIENONES
Principal Advisor
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2002
Doctor Philosophy
SYNTHESIS AND CHARACTERISATION OF 1,3- and 1,4- DIAZEPINES AND DERIVATIVES
Principal Advisor
-
Doctor Philosophy
NITRENES REARRANGEMENTS: FORMATION OF REACTIVE INTERMEDIATES AND UNUSUAL MOLECULES
Principal Advisor
Other advisors: Professor Craig Williams
Media
Enquiries
Contact Emeritus Professor Curt Wentrup directly for media enquiries about:
- Organic reaction mechanisms
- Photochemistry
- Pyrolysis
- Reactive intermediates
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