
Overview
Background
Educated at the University of Copenhagen, Denmark, and the Australian National University, Canberra. Career at the Université de Lausanne, Switzerland, and the Universität Marburg, Germany. Professor and Chair of Organic Chemistry and Head of the Organic Chemistry Section, The University of Queensland from 1985. Emeritus professor from 2008. Chair of the National Committee for Chemistry of the Australian Academy of Science 2009-2014. Editor-in-Chief, Australian Journal of Chemistry 2008-15. Editor, Journal of Analytical and Applied Pyrolysis (Elsevier, IF 3.65) 2016-. Visiting Professor Université de Pau, France, 2011-19; Visiting Professor University of Kuwait 2014-18; Visiting Professor / Special Appointed Professor Hiroshima University 2014-18. Fellow of the Australian Academy of Science. Centenary Medal of the Australian Commonwealth 2003 for research in organic and physical chemistry. David Craig Medal of the Academy of Science 2014 for research in chemistry. JSPS Fellowship (Japan) 2014. Honorary doctorate, University of Pau, France, 2014. A.J. Birch Medal of the Royal Australian Chemical Institute (RACI) for ecellence in research in organic chemistry, 2014. Leighton Medal of the RACI 2018.
Research on Unusual Molecules and Reactive Intermediates: Synthesis and Reaction Mechanism. Heterocyclic chemistry. Pyrolysis reactions. Photochemistry
Research in the Wentrup group is concerned with the discovery of novel types of molecules with new and unusual bonding patterns. Such molecules are mostly highly reactive, and special methods are required both for their generation and for their detection. The group has developed these methods over many years and acquired world-class equipment for these purposes, including flash vacuum thermolysis apparatus, cryostats for matrix isolation of reaction products at cryogenic temperatures (down to 7 K), matrix and solution photochemistry equipment, infrared, UV and mass spectrometers, as well as modern computational facilities.
This research has resulted in the synthesis and characterization of many novel compounds, including extended cumulenes of the types RN=C=C=C=X, which themselves are used in the synthesis of many novel types of molecules, some of them of potential pharmaceutical interest (quinolone antibiotics; diazepines).
The research group has a world reputation in the field of carbene and nitrene chemistry, involving reactive intermediates with sextet carbon or nitrogen. These species are also very useful in synthesis, for example in the preparation of diazepines and diazepinones, a family of pharmaceutically interesting compounds. Numerous mechanistic studies and synthetic applications of ketenes have been carried out in our group.
Active collaborations are ongoing with scientists in Australia (UQ and CSIRO), China (Suzhou), France (Pau), Germany (Oldenburg), Japan (Hiroshima), Spain (Donostia - San Sebastian), and Portugal (Coimbra).
Availability
- Emeritus Professor Curt Wentrup is:
- Not available for supervision
- Media expert
Fields of research
Qualifications
- Doctor of Philosophy, Australian National University
- Doctor of Philosophy of Science (Advanced), University of Copenhagen
- Doctoral Diploma, Institution to be confirmed
- Australian Academy of Science, Australian Academy of Science
- Royal Australian Chemical Institute, Royal Australian Chemical Institute
Research interests
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Organic, physical, and historical chemistry
Reactive intermediates, pyrolysis, photochemistry, reaction mechanism. History of science.
Research impacts
This research leads to the development of new pharmaceuticals, e.g. new antibiotics (quinolones and naphthyridones) and new leads towards a treatment for scizophrenia (diazepine molecules).
Chemical industry has used our pyrolysis techniques in specialized manufacturing processes.
Our analytical/spectroscopic work has led to cooperation with chemical and energy firms and agencies involved in forensic science, and our research has generated collaborations with many scientists at universities in Australia, Austria, Belgium, China, Denmark, France, Germany, Hungary, Japan, Portugal, Singapore, Switzerland, and USA.
Works
Search Professor Curt Wentrup’s works on UQ eSpace
2000
Journal Article
Mesoions and ketene valence isomers. Pyrrolo[1,2-a]pyridinium olates and (2-pyridyl)carbonylketenes
Ye, X., Andraos, J., Bibas, H., Wong, M. W. and Wentrup, C. (2000). Mesoions and ketene valence isomers. Pyrrolo[1,2-a]pyridinium olates and (2-pyridyl)carbonylketenes. Journal of The Chemical Society- Perkin Transactions I (1), 401-406.
2000
Journal Article
Mesoions and ketene valence isomers. Three types of rearrangement of mesoionic pyridopyrimidinylium olates involving ketene intermediates
Fiksdahl, A., Plug, C. and Wentrup, C. (2000). Mesoions and ketene valence isomers. Three types of rearrangement of mesoionic pyridopyrimidinylium olates involving ketene intermediates. Perkin Transactions II, 31 (2), 1841-1845. doi: 10.1039/b003662p
2000
Journal Article
Mesoionic pyridopyrimidinylium and pyrisooxazinylium olates and non-mesoionic pyridopyrimidinones. Structures in the solid state, solution and matrices
Plug, C., Wallfisch, B., Andersen, H. G., Bernhardt, P. V., Baker, L., Clark, G. R., Wong, M. W. and Wentrup, C. (2000). Mesoionic pyridopyrimidinylium and pyrisooxazinylium olates and non-mesoionic pyridopyrimidinones. Structures in the solid state, solution and matrices. Perkin Transactions II (2), 2096-2108.
2000
Journal Article
Acylthioketene-thioacylketene-thiet-2-one rearrangements
Ammann, J., Flammang, R., Wong, M. W. and Wentrup, C. (2000). Acylthioketene-thioacylketene-thiet-2-one rearrangements. Journal of Organic Chemistry, 65 (9), 2706-2710. doi: 10.1021/jo991776p
2000
Journal Article
Mono-, Di, and Tri-Nitrenes in the Pyridine series
Chapyshev, S., Kuhn, A., Wong, M. W. and Wentrup, C. (2000). Mono-, Di, and Tri-Nitrenes in the Pyridine series. Journal of the American Chemical Society, 122 (8), 1572-1579. doi: 10.1021/ja9931067
2000
Journal Article
The thioacyl isocyanate-acyl isothiocyanate rearrangement
Koch, R. and Wentrup, C. (2000). The thioacyl isocyanate-acyl isothiocyanate rearrangement. Perkin Transactions II (2), 1846-1850.
2000
Journal Article
The thioacyl isocyanate-acyl isothiocyanate rearrangement
Koch, R and Wentrup, C (2000). The thioacyl isocyanate-acyl isothiocyanate rearrangement. Journal of the Chemical Society-Perkin Transactions 2 (9), 1846-1850. doi: 10.1039/b003534n
2000
Journal Article
Monomer, dimers and trimers of cyanogens N-oxide, NC-CN
Barbieux-Flammang, M., Vandevoorde, S., Flammang, R., Wong, M. W., Bibas, H., Kennard, C. H. and Wentrup, C. (2000). Monomer, dimers and trimers of cyanogens N-oxide, NC-CN. Journal of The Chemical Society-Perkin Transactions II (2), 473-478.
2000
Journal Article
Mesoionic pyridopyrimidinylium and pyridooxazinylium olates and non-mesoionic pyridopyrimidinones. Structures in the solid state, solution, and matrices
Plug, C., Wallfisch, B., Andersen, H. G., Bernhardt, P. V., Baker, L. J., Clark, G. R., Wong, M. W. and Wentrup, C. (2000). Mesoionic pyridopyrimidinylium and pyridooxazinylium olates and non-mesoionic pyridopyrimidinones. Structures in the solid state, solution, and matrices. Journal of The Chemical Society-perkin Transactions 2 (10), 2096-2108. doi: 10.1039/b003933k
2000
Journal Article
Mesoions and ketene valence isomers. Pyrrolo[1,2-alpha]pyridinylium olates and (2-pyridyl)carbonylketenes
Ye, X, Andraos, J, Bibas, H, Wong, MW and Wentrup, C (2000). Mesoions and ketene valence isomers. Pyrrolo[1,2-alpha]pyridinylium olates and (2-pyridyl)carbonylketenes. Journal of the Chemical Society-Perkin Transactions 1 (3), 401-406. doi: 10.1039/a906831g
2000
Journal Article
Direct observation of a carbene-pyridine ylide by matrix IR spectroscopy. Rearrangements of 2-pyridylacylcarbenes
Kuhn, A., Plug, C. and Wentrup, C. (2000). Direct observation of a carbene-pyridine ylide by matrix IR spectroscopy. Rearrangements of 2-pyridylacylcarbenes. Journal of the American Chemical Society, 122 (9), 1945-1948. doi: 10.1021/ja993859t
2000
Journal Article
Mass spectrometric studies of dipolar systems containing an N+-X- bond
Gerbaux, P., Wentrup, C. and Flammang, R. (2000). Mass spectrometric studies of dipolar systems containing an N+-X- bond. Mass Spectrometry Review, 19 (6), 367-389. doi: 10.1002/1098-2787(2000)19:63.0.CO;2-N
1999
Journal Article
Aryliminopropadienone-C-amidoketenimine-amidinoketene-2-aminoquinolone cascades and the ynamine-isocyanate reaction
Wentrup, C., Rao, R. V. V., Frank, W., Fulloon, B. E., Moloney, D. W. J. and Mosandl, T. (1999). Aryliminopropadienone-C-amidoketenimine-amidinoketene-2-aminoquinolone cascades and the ynamine-isocyanate reaction. Journal of Organic Chemistry, 64 (10), 3608-3619. doi: 10.1021/jo982471y
1999
Journal Article
Formation and characterization of methoxy isothiocyanate (CH3ON=C=S) and methyl cyanate N-sulfide (CH3OC=N+-S-) as radical cations and neutrals in the gas phase
Flammang, R., Gerbaux, P., Barbieux-Flammang, M., Pedersen, C. T., Bech, A. T., Morkved, E. H., Wong, M. W. and Wentrup, C. (1999). Formation and characterization of methoxy isothiocyanate (CH3ON=C=S) and methyl cyanate N-sulfide (CH3OC=N+-S-) as radical cations and neutrals in the gas phase. Journal of the Chemical Society, Perkin Transactions 2 (8), 1683-1688. doi: 10.1039/a903057c
1999
Journal Article
Mass spectrometry of S=C=(C)n=C=X cumulenes
Flammang, R., Frank, W. and Wentrup, C. (1999). Mass spectrometry of S=C=(C)n=C=X cumulenes. Sulfur Reports, 21, 357-371.
1999
Journal Article
Alkoxy isothiocyanates, RO-N=C=S
Bech, A. T., Flammang, R., Pedersen, C. T., Wong, M. W. and Wentrup, C. (1999). Alkoxy isothiocyanates, RO-N=C=S. Journal of the Chemical Society, Perkin Transactions 2 (9), 1869-1873. doi: 10.1039/a903865e
1999
Journal Article
(2-Pyridyl)iminopropadienone
Plüg, Carsten, Frank, Wilhelm and Wentrup, Curt (1999). (2-Pyridyl)iminopropadienone. Journal of the Chemical Society, Perkin Transactions 2 (6), 1087-1093. doi: 10.1039/a901632e
1998
Journal Article
On the di-1-naphthylcarbene-dibenzofluorene rearrangement and the ethylenization of diarylcarbinols
Regimbald-Krnel M. and Wentrup C. (1998). On the di-1-naphthylcarbene-dibenzofluorene rearrangement and the ethylenization of diarylcarbinols. Journal of Organic Chemistry, 63 (23), 8417-8423. doi: 10.1021/jo981397g
1998
Journal Article
Nitrile N-selenide (RC=NSe) and isoselenocyanate (RN=C=Se) neutrals and radical cations by selenation of nitriles and isonitriles: Tandem mass spectrometry and ab initio studies
Gerbaux, Pascal, Flammang, Robert, Mørkved, Eva H., Wong, Ming Wah and Wentrup, Curt (1998). Nitrile N-selenide (RC=NSe) and isoselenocyanate (RN=C=Se) neutrals and radical cations by selenation of nitriles and isonitriles: Tandem mass spectrometry and ab initio studies. Journal of Physical Chemistry A, 102 (45), 9021-9030. doi: 10.1021/jp9824454
1998
Journal Article
Dihydro-1,3-diazepinones and diazabicyclo[3.2.0]heptenones from pyridyl azides
Reisinger, Ales, Koch, Rainer and Wentrup, Curt (1998). Dihydro-1,3-diazepinones and diazabicyclo[3.2.0]heptenones from pyridyl azides. Journal of the Chemical Society - Perkin Transactions 1, 29 (15), 2247-2249. doi: 10.1039/a804831b
Funding
Supervision
Availability
- Emeritus Professor Curt Wentrup is:
- Not available for supervision
Supervision history
Completed supervision
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2006
Doctor Philosophy
SYNTHESES AND REACTIONS OF IMINOPROPADIENONES, SYDNONES AND OXAZINONES
Principal Advisor
Other advisors: Professor Craig Williams
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2002
Doctor Philosophy
HETEROCYCLIC SYNTHESIS BASED ON IMINOPROPADIENONES
Principal Advisor
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2002
Doctor Philosophy
SYNTHESIS AND CHARACTERISATION OF 1,3- and 1,4- DIAZEPINES AND DERIVATIVES
Principal Advisor
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Doctor Philosophy
NITRENES REARRANGEMENTS: FORMATION OF REACTIVE INTERMEDIATES AND UNUSUAL MOLECULES
Principal Advisor
Other advisors: Professor Craig Williams
Media
Enquiries
Contact Emeritus Professor Curt Wentrup directly for media enquiries about:
- Organic reaction mechanisms
- Photochemistry
- Pyrolysis
- Reactive intermediates
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