
Overview
Background
Educated at the University of Copenhagen, Denmark, and the Australian National University, Canberra. Career at the Université de Lausanne, Switzerland, and the Universität Marburg, Germany. Professor and Chair of Organic Chemistry and Head of the Organic Chemistry Section, The University of Queensland from 1985. Emeritus professor from 2008. Chair of the National Committee for Chemistry of the Australian Academy of Science 2009-2014. Editor-in-Chief, Australian Journal of Chemistry 2008-15. Editor, Journal of Analytical and Applied Pyrolysis (Elsevier, IF 3.65) 2016-. Visiting Professor Université de Pau, France, 2011-19; Visiting Professor University of Kuwait 2014-18; Visiting Professor / Special Appointed Professor Hiroshima University 2014-18. Fellow of the Australian Academy of Science. Centenary Medal of the Australian Commonwealth 2003 for research in organic and physical chemistry. David Craig Medal of the Academy of Science 2014 for research in chemistry. JSPS Fellowship (Japan) 2014. Honorary doctorate, University of Pau, France, 2014. A.J. Birch Medal of the Royal Australian Chemical Institute (RACI) for ecellence in research in organic chemistry, 2014. Leighton Medal of the RACI 2018.
Research on Unusual Molecules and Reactive Intermediates: Synthesis and Reaction Mechanism. Heterocyclic chemistry. Pyrolysis reactions. Photochemistry
Research in the Wentrup group is concerned with the discovery of novel types of molecules with new and unusual bonding patterns. Such molecules are mostly highly reactive, and special methods are required both for their generation and for their detection. The group has developed these methods over many years and acquired world-class equipment for these purposes, including flash vacuum thermolysis apparatus, cryostats for matrix isolation of reaction products at cryogenic temperatures (down to 7 K), matrix and solution photochemistry equipment, infrared, UV and mass spectrometers, as well as modern computational facilities.
This research has resulted in the synthesis and characterization of many novel compounds, including extended cumulenes of the types RN=C=C=C=X, which themselves are used in the synthesis of many novel types of molecules, some of them of potential pharmaceutical interest (quinolone antibiotics; diazepines).
The research group has a world reputation in the field of carbene and nitrene chemistry, involving reactive intermediates with sextet carbon or nitrogen. These species are also very useful in synthesis, for example in the preparation of diazepines and diazepinones, a family of pharmaceutically interesting compounds. Numerous mechanistic studies and synthetic applications of ketenes have been carried out in our group.
Active collaborations are ongoing with scientists in Australia (UQ and CSIRO), China (Suzhou), France (Pau), Germany (Oldenburg), Japan (Hiroshima), Spain (Donostia - San Sebastian), and Portugal (Coimbra).
Availability
- Emeritus Professor Curt Wentrup is:
- Not available for supervision
- Media expert
Fields of research
Qualifications
- Doctor of Philosophy, Australian National University
- Doctor of Philosophy of Science (Advanced), University of Copenhagen
- Doctoral Diploma, Institution to be confirmed
- Australian Academy of Science, Australian Academy of Science
- Royal Australian Chemical Institute, Royal Australian Chemical Institute
Research interests
-
Organic, physical, and historical chemistry
Reactive intermediates, pyrolysis, photochemistry, reaction mechanism. History of science.
Research impacts
This research leads to the development of new pharmaceuticals, e.g. new antibiotics (quinolones and naphthyridones) and new leads towards a treatment for scizophrenia (diazepine molecules).
Chemical industry has used our pyrolysis techniques in specialized manufacturing processes.
Our analytical/spectroscopic work has led to cooperation with chemical and energy firms and agencies involved in forensic science, and our research has generated collaborations with many scientists at universities in Australia, Austria, Belgium, China, Denmark, France, Germany, Hungary, Japan, Portugal, Singapore, Switzerland, and USA.
Works
Search Professor Curt Wentrup’s works on UQ eSpace
1986
Journal Article
ESR Observation of Thermally Produced Triplet Nitrenes and Photochemically Produced Triplet Cycloheptatrienylidenes
Kuzaj M., Luerssen H. and Wentrup C. (1986). ESR Observation of Thermally Produced Triplet Nitrenes and Photochemically Produced Triplet Cycloheptatrienylidenes. Angewandte Chemie-International Edition in English, 25 (5), 480-482. doi: 10.1002/anie.198604801
1986
Journal Article
Nitrile Ylides and Azirines: Gas‐Phase Generation from 2,3‐Dihydro‐1,4,λ5‐oxazaphospholes and Matrix Isolation
Wentrup C., Fischer S., Berstermann H.-M., Kuzaj M., Luerssen H. and Burger K. (1986). Nitrile Ylides and Azirines: Gas‐Phase Generation from 2,3‐Dihydro‐1,4,λ5‐oxazaphospholes and Matrix Isolation. Angewandte Chemie-International Edition in English, 25 (1), 85-86. doi: 10.1002/anie.198600851
1985
Journal Article
MECHANISM OF FRAGMENTATION OF ALKYLIDENE-MELDRUMS ACIDS - CARBOXYKETENE, VINYLKETENE, AND METHYLENEKETENE INTERMEDIATES FROM 5-CYCLOPENTYLIDENE-2,2-DIMETHYL-1,3-DIOXANE-4,6-DIONE
WENTRUP, C, GROSS, G, BERSTERMANN, HM and LORENCAK, P (1985). MECHANISM OF FRAGMENTATION OF ALKYLIDENE-MELDRUMS ACIDS - CARBOXYKETENE, VINYLKETENE, AND METHYLENEKETENE INTERMEDIATES FROM 5-CYCLOPENTYLIDENE-2,2-DIMETHYL-1,3-DIOXANE-4,6-DIONE. Journal of Organic Chemistry, 50 (16), 2877-2881. doi: 10.1021/jo00216a015
1985
Journal Article
4-Alkylideneisoxazol-5-Ones - Synthesis, Tautomerism, and Rearrangement to Pyrroles
Wollweber, HJ and Wentrup, C (1985). 4-Alkylideneisoxazol-5-Ones - Synthesis, Tautomerism, and Rearrangement to Pyrroles. Journal of Organic Chemistry, 50 (12), 2041-2047. doi: 10.1021/jo00212a007
1985
Journal Article
NITRILE IMINES - THERMAL GENERATION, DIRECT OBSERVATION, AND SUBSEQUENT TRAPPING
WENTRUP, C, FISCHER, S, MAQUESTIAU, A and FLAMMANG, R (1985). NITRILE IMINES - THERMAL GENERATION, DIRECT OBSERVATION, AND SUBSEQUENT TRAPPING. Angewandte Chemie-International Edition in English, 24 (1), 56-57. doi: 10.1002/anie.198500561
1985
Conference Publication
2-Azaadamant-1-Ene and Other Matrix-Isolated Strained Bridgehead Imines - Bridgehead Syn-Anti Isomerism
Michl, J, Radziszewski, JG, Downing, JW, Wentrup, C, Kaszynski, P, Jawdosiuk, M and Kovacic, P (1985). 2-Azaadamant-1-Ene and Other Matrix-Isolated Strained Bridgehead Imines - Bridgehead Syn-Anti Isomerism. WASHINGTON: AMER CHEMICAL SOC.
1985
Journal Article
FORCE FIELD-SCF CALCULATIONS ON CYCLOPROPENE INTERMEDIATES IN CARBENE REARRANGEMENTS - COMPARISON WITH EXPERIMENT
WENTRUP, C, MAYOR, C, BECKER, J and LINDNER, HJ (1985). FORCE FIELD-SCF CALCULATIONS ON CYCLOPROPENE INTERMEDIATES IN CARBENE REARRANGEMENTS - COMPARISON WITH EXPERIMENT. Tetrahedron, 41 (8), 1601-1612. doi: 10.1016/S0040-4020(01)96400-2
1985
Journal Article
GEOMETRICAL-ISOMERS OF A BRIDGEHEAD IMINE - (E)-2-AZABICYCLO[3.2.1]OCT-1-ENE AND (Z)-2-AZABICYCLO[3.2.1]OCT-1-ENE AND 2-AZABICYCLO[2.2.2]OCT-1-ENE
RADZISZEWSKI, JG, DOWNING, JW, WENTRUP, C, KASZYNSKI, P, JAWDOSIUK, M, KOVACIC, P and MICHL, J (1985). GEOMETRICAL-ISOMERS OF A BRIDGEHEAD IMINE - (E)-2-AZABICYCLO[3.2.1]OCT-1-ENE AND (Z)-2-AZABICYCLO[3.2.1]OCT-1-ENE AND 2-AZABICYCLO[2.2.2]OCT-1-ENE. Journal of the American Chemical Society, 107 (9), 2799-2801. doi: 10.1021/ja00295a038
1984
Journal Article
A NOVEL KETOKETENE KETOKETENE REARRANGEMENT
WENTRUP, C and NETSCH, KP (1984). A NOVEL KETOKETENE KETOKETENE REARRANGEMENT. Angewandte Chemie-International Edition in English, 23 (10), 802-802. doi: 10.1002/anie.198408021
1984
Journal Article
ACYLKETENES AND THIOACYLKETENES - SYNTHESIS OF 3-BENZOYL-4-PHENYLTHIET-2-ONE
WENTRUP, C, WINTER, HW, GROSS, G, NETSCH, KP, KOLLENZ, G, OTT, W and BIEDERMANN, AG (1984). ACYLKETENES AND THIOACYLKETENES - SYNTHESIS OF 3-BENZOYL-4-PHENYLTHIET-2-ONE. Angewandte Chemie-International Edition in English, 23 (10), 800-802. doi: 10.1002/anie.198408001
1984
Journal Article
2-AZAADAMANT-1-ENE AND 4-AZAPROTOADAMANT-3-ENE
RADZISZEWSKI, JG, DOWNING, JW, WENTRUP, C, KASZYNSKI, P, JAWDOSIUK, M, KOVACIC, P and MICHL, J (1984). 2-AZAADAMANT-1-ENE AND 4-AZAPROTOADAMANT-3-ENE. Journal of the American Chemical Society, 106 (25), 7996-7998. doi: 10.1021/ja00337a072
1984
Journal Article
The Millimeter Wave Rotational Spectrum of N-Cyanomethanimine, Ch2Ncn
Winnewisser, M, Winnewisser, BP and Wentrup, C (1984). The Millimeter Wave Rotational Spectrum of N-Cyanomethanimine, Ch2Ncn. Journal of Molecular Spectroscopy, 105 (1), 193-205. doi: 10.1016/0022-2852(84)90111-5
1984
Journal Article
REACTIVE NITROGENOUS MOLECULES FROM MELDRUMS ACID-DERIVATIVES, PYRROLE-2,3-DIONES, AND ISOXAZOLONES
BRIEHL, H, LUKOSCH, A and WENTRUP, C (1984). REACTIVE NITROGENOUS MOLECULES FROM MELDRUMS ACID-DERIVATIVES, PYRROLE-2,3-DIONES, AND ISOXAZOLONES. Journal of Organic Chemistry, 49 (15), 2772-2779. doi: 10.1021/jo00189a025
1984
Conference Publication
Twisting the C=N Double-Bond - Bridgehead Imines
Radziszewski, JG, Jawdosiuk, M, Downing, JW, Kaszynski, P, Wentrup, C, Kovacic, P and Michl, J (1984). Twisting the C=N Double-Bond - Bridgehead Imines. WASHINGTON: AMER CHEMICAL SOC.
1984
Journal Article
SYNTHESIS OF 1-AZAAZULENE AND BENZ[A]AZULENE BY CARBENE REARRANGEMENT
WENTRUP, C and BECKER, J (1984). SYNTHESIS OF 1-AZAAZULENE AND BENZ[A]AZULENE BY CARBENE REARRANGEMENT. Journal of the American Chemical Society, 106 (12), 3705-3706. doi: 10.1021/ja00324a070
1983
Journal Article
THIETONES, OXETONES, AND AZETONES
WENTRUP, C and GROSS, G (1983). THIETONES, OXETONES, AND AZETONES. Angewandte Chemie-International Edition in English, 22 (7), 543-543. doi: 10.1002/anie.198305431
1983
Journal Article
(IMINOMETHYLIDENE)PHOSPHINES (RP=C=NR)
WENTRUP, C, BRIEHL, H, BECKER, G, UHL, G, WESSELY, HJ, MAQUESTIAU, A and FLAMMANG, R (1983). (IMINOMETHYLIDENE)PHOSPHINES (RP=C=NR). Journal of the American Chemical Society, 105 (24), 7194-7195. doi: 10.1021/ja00362a042
1983
Journal Article
THERMAL AZULENE REARRANGEMENTS - SYNTHESIS AND THERMOLYSIS OF [6-C-13]AZULENE
GUGEL, H, ZELLER, KP and WENTRUP, C (1983). THERMAL AZULENE REARRANGEMENTS - SYNTHESIS AND THERMOLYSIS OF [6-C-13]AZULENE. Chemische Berichte-Recueil, 116 (8), 2775-2784. doi: 10.1002/cber.19831160806
1983
Journal Article
1,2-CYCLOHEXADIENE
WENTRUP, C, GROSS, G, MAQUESTIAU, A and FLAMMANG, R (1983). 1,2-CYCLOHEXADIENE. Angewandte Chemie-International Edition in English, 22 (7), 542-543. doi: 10.1002/anie.198305421
1982
Journal Article
HETEROCYCLIC REARRANGEMENTS - NEW CUMULENES AND ACETYLENES
WENTRUP, C (1982). HETEROCYCLIC REARRANGEMENTS - NEW CUMULENES AND ACETYLENES. Bulletin Des Societes Chimiques Belges, 91 (12), 997-1002.
Funding
Supervision
Availability
- Emeritus Professor Curt Wentrup is:
- Not available for supervision
Supervision history
Completed supervision
-
2006
Doctor Philosophy
SYNTHESES AND REACTIONS OF IMINOPROPADIENONES, SYDNONES AND OXAZINONES
Principal Advisor
Other advisors: Professor Craig Williams
-
2002
Doctor Philosophy
HETEROCYCLIC SYNTHESIS BASED ON IMINOPROPADIENONES
Principal Advisor
-
2002
Doctor Philosophy
SYNTHESIS AND CHARACTERISATION OF 1,3- and 1,4- DIAZEPINES AND DERIVATIVES
Principal Advisor
-
Doctor Philosophy
NITRENES REARRANGEMENTS: FORMATION OF REACTIVE INTERMEDIATES AND UNUSUAL MOLECULES
Principal Advisor
Other advisors: Professor Craig Williams
Media
Enquiries
Contact Emeritus Professor Curt Wentrup directly for media enquiries about:
- Organic reaction mechanisms
- Photochemistry
- Pyrolysis
- Reactive intermediates
Need help?
For help with finding experts, story ideas and media enquiries, contact our Media team: