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Emeritus Professor Curt Wentrup
Emeritus Professor

Curt Wentrup

Email: 
Phone: 
+61 7 336 53817

Overview

Background

Educated at the University of Copenhagen, Denmark, and the Australian National University, Canberra. Career at the Université de Lausanne, Switzerland, and the Universität Marburg, Germany. Professor and Chair of Organic Chemistry and Head of the Organic Chemistry Section, The University of Queensland from 1985. Emeritus professor from 2008. Chair of the National Committee for Chemistry of the Australian Academy of Science 2009-2014. Editor-in-Chief, Australian Journal of Chemistry 2008-15. Editor, Journal of Analytical and Applied Pyrolysis (Elsevier, IF 3.65) 2016-. Visiting Professor Université de Pau, France, 2011-19; Visiting Professor University of Kuwait 2014-18; Visiting Professor / Special Appointed Professor Hiroshima University 2014-18. Fellow of the Australian Academy of Science. Centenary Medal of the Australian Commonwealth 2003 for research in organic and physical chemistry. David Craig Medal of the Academy of Science 2014 for research in chemistry. JSPS Fellowship (Japan) 2014. Honorary doctorate, University of Pau, France, 2014. A.J. Birch Medal of the Royal Australian Chemical Institute (RACI) for ecellence in research in organic chemistry, 2014. Leighton Medal of the RACI 2018.

Research on Unusual Molecules and Reactive Intermediates: Synthesis and Reaction Mechanism. Heterocyclic chemistry. Pyrolysis reactions. Photochemistry

Research in the Wentrup group is concerned with the discovery of novel types of molecules with new and unusual bonding patterns. Such molecules are mostly highly reactive, and special methods are required both for their generation and for their detection. The group has developed these methods over many years and acquired world-class equipment for these purposes, including flash vacuum thermolysis apparatus, cryostats for matrix isolation of reaction products at cryogenic temperatures (down to 7 K), matrix and solution photochemistry equipment, infrared, UV and mass spectrometers, as well as modern computational facilities.

This research has resulted in the synthesis and characterization of many novel compounds, including extended cumulenes of the types RN=C=C=C=X, which themselves are used in the synthesis of many novel types of molecules, some of them of potential pharmaceutical interest (quinolone antibiotics; diazepines).

The research group has a world reputation in the field of carbene and nitrene chemistry, involving reactive intermediates with sextet carbon or nitrogen. These species are also very useful in synthesis, for example in the preparation of diazepines and diazepinones, a family of pharmaceutically interesting compounds. Numerous mechanistic studies and synthetic applications of ketenes have been carried out in our group.

Active collaborations are ongoing with scientists in Australia (UQ and CSIRO), China (Suzhou), France (Pau), Germany (Oldenburg), Japan (Hiroshima), Spain (Donostia - San Sebastian), and Portugal (Coimbra).

Availability

Emeritus Professor Curt Wentrup is:
Not available for supervision
Media expert

Qualifications

  • Doctor of Philosophy, Australian National University
  • Doctor of Philosophy of Science (Advanced), University of Copenhagen
  • Doctoral Diploma, Institution to be confirmed
  • Australian Academy of Science, Australian Academy of Science
  • Royal Australian Chemical Institute, Royal Australian Chemical Institute

Research interests

  • Organic, physical, and historical chemistry

    Reactive intermediates, pyrolysis, photochemistry, reaction mechanism. History of science.

Research impacts

This research leads to the development of new pharmaceuticals, e.g. new antibiotics (quinolones and naphthyridones) and new leads towards a treatment for scizophrenia (diazepine molecules).

Chemical industry has used our pyrolysis techniques in specialized manufacturing processes.

Our analytical/spectroscopic work has led to cooperation with chemical and energy firms and agencies involved in forensic science, and our research has generated collaborations with many scientists at universities in Australia, Austria, Belgium, China, Denmark, France, Germany, Hungary, Japan, Portugal, Singapore, Switzerland, and USA.

Works

Search Professor Curt Wentrup’s works on UQ eSpace

433 works between 1966 and 2024

141 - 160 of 433 works

2010

Journal Article

2-pyridylnitrene and 3-pyridazylcarbene and their relationship via ring-expansion, ring-opening, ring-contraction, and fragmentation

Kvaskoff, David, Bednarek, Pawel and Wentrup, Curt (2010). 2-pyridylnitrene and 3-pyridazylcarbene and their relationship via ring-expansion, ring-opening, ring-contraction, and fragmentation. Journal of Organic Chemistry, 75 (5), 1600-1611. doi: 10.1021/jo902570d

2-pyridylnitrene and 3-pyridazylcarbene and their relationship via ring-expansion, ring-opening, ring-contraction, and fragmentation

2010

Conference Publication

Thioketenes and iminopropadienethiones RN=C=C=C=S from isoxazolones

Kvaskoff, David and Wentrup, Curt (2010). Thioketenes and iminopropadienethiones RN=C=C=C=S from isoxazolones. Heron Island Conference on Reactive Intermediates & Unusual Molecules, Heron Island, QLD, Australia, 10-16 July 2010. Melbourne, VIC, Australia: Commonwealth Scientific and Industrial Research Organization (CSIRO) in co-operation with the Australian Academy of Science. doi: 10.1071/CH10340

Thioketenes and iminopropadienethiones RN=C=C=C=S from isoxazolones

2010

Journal Article

The benzyne story

Wentrup, Curt (2010). The benzyne story. Australian Journal of Chemistry, 63 (7), 979-986. doi: 10.1071/CH10179

The benzyne story

2009

Journal Article

Microwave-induced molecular rearrangements. Flash thermolysis in the gas-phase and in solution: Synthesis of quinolones and naphthyridones

Lecoq, Delphine, Chalmers, Benjamin A., Veedu, Rakesh N., Kvaskoff, David, Bernhardt, Paul V. and Wentrup, Curt (2009). Microwave-induced molecular rearrangements. Flash thermolysis in the gas-phase and in solution: Synthesis of quinolones and naphthyridones. Australian Journal of Chemistry, 62 (12), 1631-1638. doi: 10.1071/CH09447

Microwave-induced molecular rearrangements. Flash thermolysis in the gas-phase and in solution: Synthesis of quinolones and naphthyridones

2009

Journal Article

Highly twisted C=C double bonds in 4-methyleneisoxazolones

Kvaskoff, David, Bernhardt, Paul V., Koch, Rainer and Wentrup, Curt (2009). Highly twisted C=C double bonds in 4-methyleneisoxazolones. Australian Journal of Chemistry, 62 (9), 1068-1078. doi: 10.1071/CH09359

Highly twisted C=C double bonds in 4-methyleneisoxazolones

2009

Conference Publication

ORGN 239-Interconversion of reactive intermediates: Nitrenes, diradicals, carbenes and ylides

Wentrup, Curt (2009). ORGN 239-Interconversion of reactive intermediates: Nitrenes, diradicals, carbenes and ylides. WASHINGTON: AMER CHEMICAL SOC.

ORGN 239-Interconversion of reactive intermediates: Nitrenes, diradicals, carbenes and ylides

2009

Journal Article

Fluoroquinolones from imidoylketenes and iminopropadienones, R-N=C=C=C=O

Fulloon, Belinda E. and Wentrup, Curt (2009). Fluoroquinolones from imidoylketenes and iminopropadienones, R-N=C=C=C=O. Australian Journal of Chemistry, 62 (2), 115-120. doi: 10.1071/CH08515

Fluoroquinolones from imidoylketenes and iminopropadienones, R-N=C=C=C=O

2009

Journal Article

Interconversion of nitrenes, azirenes, and diradicals: Rearrangement of 3-isoquinolylnitrene to o-cyanophenylketenimine and 1-cyanoisoindole

Vosswinkel, M., Luerssen, H., Kvaskoff, D. and Wentrup, Curt (2009). Interconversion of nitrenes, azirenes, and diradicals: Rearrangement of 3-isoquinolylnitrene to o-cyanophenylketenimine and 1-cyanoisoindole. Journal of Organic Chemistry, 74 (3), 1171-1178. doi: 10.1021/jo802273y

Interconversion of nitrenes, azirenes, and diradicals: Rearrangement of 3-isoquinolylnitrene to o-cyanophenylketenimine and 1-cyanoisoindole

2009

Journal Article

Ring opening and ring expansion of 8-cyano-tetrazolo[1,5-alpha]pyridine with secondary amines. Reactions of azides, tetrazoles and nitrenes with nucleophiles, part 2

Addicott, Chris, Bernhardt, Paul V. and Wentrup, Curt (2009). Ring opening and ring expansion of 8-cyano-tetrazolo[1,5-alpha]pyridine with secondary amines. Reactions of azides, tetrazoles and nitrenes with nucleophiles, part 2. ARKIVOC, 2009 (vi), 30-37. doi: 10.3998/ark.5550190.0010.604

Ring opening and ring expansion of 8-cyano-tetrazolo[1,5-alpha]pyridine with secondary amines. Reactions of azides, tetrazoles and nitrenes with nucleophiles, part 2

2009

Journal Article

Interconversion of nitrenes, carbenes, and nitrile ylides by ring expansion, ring opening, ring contraction, and ring closure: 3-quinolylnitrene, 2-quinoxalylcarbene, and 3-quinolylcarbene

Kvaskoff, David, Mitschke, Ullrich, Addicott, Chris, Finnerty, Justin, Bednarek, Pawel and Wentrup, Curt (2009). Interconversion of nitrenes, carbenes, and nitrile ylides by ring expansion, ring opening, ring contraction, and ring closure: 3-quinolylnitrene, 2-quinoxalylcarbene, and 3-quinolylcarbene. Australian Journal of Chemistry, 62 (3), 275-286. doi: 10.1071/CH08523

Interconversion of nitrenes, carbenes, and nitrile ylides by ring expansion, ring opening, ring contraction, and ring closure: 3-quinolylnitrene, 2-quinoxalylcarbene, and 3-quinolylcarbene

2009

Journal Article

The Australian Journal of Chemistry - Its New Publishing Concept

Wentrup, Curt (2009). The Australian Journal of Chemistry - Its New Publishing Concept. Australian Journal of Chemistry, 62 (1), 1-2. doi: 10.1071/CH09022

The Australian Journal of Chemistry - Its New Publishing Concept

2008

Journal Article

Reaction of iminopropadienones with amines - Formation of zwitterionic intermediates, ketenes, and ketenimines

Naduvile Veedu, Rakesh, Kokas, Okanya J., Couturier-Tamburelli, Isabelle, Koch, Rainer, Aycard, Jean-Pierre, Borget, Fabien and Wentrup, Curt (2008). Reaction of iminopropadienones with amines - Formation of zwitterionic intermediates, ketenes, and ketenimines. Journal of Physical Chemistry A, 112 (40), 9742-9750. doi: 10.1021/jp803351q

Reaction of iminopropadienones with amines - Formation of zwitterionic intermediates, ketenes, and ketenimines

2008

Journal Article

Reaction of iminopropadienones with amines: Mechanistic explanations of zwitterionic intermediate, ketene and ketenimine formation

Koch, Rainer, Finnerty, Justin J., Bruhn, Torsten, Borget, Fabien and Wentrup, Curt (2008). Reaction of iminopropadienones with amines: Mechanistic explanations of zwitterionic intermediate, ketene and ketenimine formation. Journal of Physical Chemistry A, 112 (38), 8999-9004. doi: 10.1021/jp803352m

Reaction of iminopropadienones with amines: Mechanistic explanations of zwitterionic intermediate, ketene and ketenimine formation

2008

Journal Article

2-pyridyinitrene from tetrazolo[1,5-a]pyridine and Pyrido[2,3-a][1,2,4]oxadiazol-2-one

McCluskey, Adam and Wentrup, Curt (2008). 2-pyridyinitrene from tetrazolo[1,5-a]pyridine and Pyrido[2,3-a][1,2,4]oxadiazol-2-one. Journal of Organic Chemistry, 73 (16), 6265-6267. doi: 10.1021/jo800899t

2-pyridyinitrene from tetrazolo[1,5-a]pyridine and Pyrido[2,3-a][1,2,4]oxadiazol-2-one

2008

Journal Article

Tetra-tert-butyltrioxabicyclo[3.3.1]nonadienedicarboxylic acid: Optical resolution, absolute configuration and application in chiral discrimination

Kremsner, Jennifer, Wallfisch, Bianca C., Belaj, Ferdinand, Uray, Georg, Kappe, C. Oliver, Wentrup, Curt and Kollenz, Gert (2008). Tetra-tert-butyltrioxabicyclo[3.3.1]nonadienedicarboxylic acid: Optical resolution, absolute configuration and application in chiral discrimination. European Journal of Organic Chemistry, 2008 (19), 3382-3388. doi: 10.1002/ejoc.200800109

Tetra-tert-butyltrioxabicyclo[3.3.1]nonadienedicarboxylic acid: Optical resolution, absolute configuration and application in chiral discrimination

2008

Journal Article

1H-1,3-diazepines and ketenimines from cyanotetrazolopyridines

Addicott, Chris and Wentrup, Curt (2008). 1H-1,3-diazepines and ketenimines from cyanotetrazolopyridines. Australian Journal of Chemistry, 61 (8), 592-599. doi: 10.1071/CH08252

1H-1,3-diazepines and ketenimines from cyanotetrazolopyridines

2008

Journal Article

Twisted push-pull ethylenes

Naduvile Veedu, Rakesh, Bernhardt, Paul V., Koch, Rainer and Wentrup, Curt (2008). Twisted push-pull ethylenes. Australian Journal of Chemistry, 61 (10), 805-812. doi: 10.1071/CH08277

Twisted push-pull ethylenes

2007

Journal Article

Carboxyketenes, methyleneketenes, vinylketenes, oxetanediones, ynols, and ylidid ketenes from Meldrum's acid derivatives

George, Lisa, Wong, M. and Wentrup, Curt (2007). Carboxyketenes, methyleneketenes, vinylketenes, oxetanediones, ynols, and ylidid ketenes from Meldrum's acid derivatives. Organic & Biomolecular Chemistry, 5 (9), 1437-1441. doi: 10.1039/b702518a

Carboxyketenes, methyleneketenes, vinylketenes, oxetanediones, ynols, and ylidid ketenes from Meldrum's acid derivatives

2007

Journal Article

Carboxyketenes from 4-Hydroxy-1,3-oxazin-6-ones and Meldrum's acid derivatives

George, L., Naduvile Veedu, R., Sheibani, H., Taherpour, A., Flammang, R. and Wentrup, C. (2007). Carboxyketenes from 4-Hydroxy-1,3-oxazin-6-ones and Meldrum's acid derivatives. Journal of Organic Chemistry, 72 (4), 1399-1404. doi: 10.1021/jo062319t

Carboxyketenes from 4-Hydroxy-1,3-oxazin-6-ones and Meldrum's acid derivatives

2006

Journal Article

Oxoketene-oxoketene, imidoylketene-imidoylketene and oxoketenimine-imidoylketene rearrangements. 1,3-shifts of phenyl groups

George, L., Netsch, K. P., Penn, G., Kollenz, G. and Wentrup, C. (2006). Oxoketene-oxoketene, imidoylketene-imidoylketene and oxoketenimine-imidoylketene rearrangements. 1,3-shifts of phenyl groups. Organic & Biomolecular Chemistry, 4 (3), 558-564. doi: 10.1039/b515917b

Oxoketene-oxoketene, imidoylketene-imidoylketene and oxoketenimine-imidoylketene rearrangements. 1,3-shifts of phenyl groups

Funding

Past funding

  • 2012 - 2013
    Heron Island Conference on reactive intermediate and unusual molecules
    Ian Potter Foundation
    Open grant
  • 2010
    UQ Travel Awards Category 1, Fabian Borget
    UQ Travel Grants Scheme
    Open grant
  • 2007 - 2008
    An X-Ray Diffraction Facility for Molecular Structure Determination
    ARC Linkage Infrastructure, Equipment and Facilities
    Open grant
  • 2007 - 2009
    Reactive intermediates and microwave-assisted organic reactions
    ARC Discovery Projects
    Open grant
  • 2007
    Research in pre-biotic chemistry
    UQ Travel Grants Scheme
    Open grant
  • 2004
    Research conference grant for Prof Josef Michl, University of Colorado, Boulder, to attend Heron Island Conference on reactive intermediates and unusual molecules, 17-23 July 2004
    Potter Foundation
    Open grant
  • 2004 - 2006
    New mechanisms and methods in carbene and nitrene chemistry
    ARC Discovery Projects
    Open grant
  • 2003 - 2005
    Bimolecular chemistry at very low temperature
    ARC Linkage International
    Open grant
  • 2002
    To expand work on cryogenic matrix isolation research.
    UQ Travel Grants Scheme
    Open grant
  • 2001 - 2003
    Chemistry of Iminopropadienones and Related Compounds.
    ARC Australian Research Council (Large grants)
    Open grant
  • 2000
    Novel approaches to heterocyclic synthesis.
    ARC Australian Research Council (Small grants)
    Open grant
  • 1997
    Brisbane Advanced Mass Spectrometry Facility
    Research Infrastructure (Equip & Fac) Program
    Open grant
  • 1997
    Synthesis of 1,3-diazepines
    ARC Australian Research Council (Small grants)
    Open grant
  • 1996 - 1997
    International Network in Advanced Techniques of Applied Molecular Science
    Quality Funds Round 3
    Open grant
  • 1996
    Pulsed pyrolysis
    ARC Australian Research Council (Small grants)
    Open grant

Supervision

Availability

Emeritus Professor Curt Wentrup is:
Not available for supervision

Supervision history

Completed supervision

  • 2006

    Doctor Philosophy

    SYNTHESES AND REACTIONS OF IMINOPROPADIENONES, SYDNONES AND OXAZINONES

    Principal Advisor

    Other advisors: Professor Craig Williams

  • 2002

    Doctor Philosophy

    HETEROCYCLIC SYNTHESIS BASED ON IMINOPROPADIENONES

    Principal Advisor

  • 2002

    Doctor Philosophy

    SYNTHESIS AND CHARACTERISATION OF 1,3- and 1,4- DIAZEPINES AND DERIVATIVES

    Principal Advisor

  • Doctor Philosophy

    NITRENES REARRANGEMENTS: FORMATION OF REACTIVE INTERMEDIATES AND UNUSUAL MOLECULES

    Principal Advisor

    Other advisors: Professor Craig Williams

Media

Enquiries

Contact Emeritus Professor Curt Wentrup directly for media enquiries about:

  • Organic reaction mechanisms
  • Photochemistry
  • Pyrolysis
  • Reactive intermediates

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