
Overview
Background
Michael (Mike) Roberts is a NHMRC Senior Principal Research Fellow and Emeritus Professor of Clinical Pharmacology & Therapeutics and Director of the Therapeutics Research Centre in the Diamantina Institute at The University of Queensland, which is based in the Translational Research Institute adjacent to the Princess Alexandra Hospital in Brisbane, Qld, Australia. He is also Professor of Therapeutics & Pharmaceutical Science at the University of South Australia with laboratories in the Basil Hetzel Institute at The Queen Elizabeth Hospital in Adelaide, South Australia.
Availability
- Emeritus Professor Michael Roberts is:
- Available for supervision
- Media expert
Fields of research
Qualifications
- Bachelor of Pharmacy, University of Adelaide
- Masters (Coursework) of Science, University of Sydney
- Doctor of Philosophy, University of Sydney
- Masters (Coursework) of Business Administration, The University of Queensland
- Doctoral Diploma of Science (Advanced), University of Sydney
Works
Search Professor Michael Roberts’s works on UQ eSpace
2016
Journal Article
What is the effect of obesity on piperacillin and meropenem trough concentrations in critically ill patients?
Alobaid, Abdulaziz S., Brinkmann, Alexander, Frey, Otto R., Roehr, Anka C., Luque, Sonia, Grau, Santiago, Wong, Gloria, Abdul-Aziz, Mohd-Hafiz, Roberts, Michael S., Lipman, Jeffrey and Roberts, Jason A. (2016). What is the effect of obesity on piperacillin and meropenem trough concentrations in critically ill patients?. Journal of Antimicrobial Chemotherapy, 71 (3) dkv412, 696-702. doi: 10.1093/jac/dkv412
2016
Journal Article
SaMpling antibiotics in renal replacement therapy (SMARRT): an observational pharmacokinetic study in critically ill patients
Roberts, Jason A., Choi, Gordon Y. S., Joynt, Gavin M., Paul, Sanjoy K., Deans, Renae, Peake, Sandra, Cole, Louise, Stephens, Dianne, Bellomo, Rinaldo, Turnidge, John, Wallis, Steven C., Roberts, Michael S., Roberts, Darren M., Lassig-Smith, Melissa, Starr, Therese and Lipman, Jeffrey (2016). SaMpling antibiotics in renal replacement therapy (SMARRT): an observational pharmacokinetic study in critically ill patients. Bmc Infectious Diseases, 16 (1) 103, 103.1-103.8. doi: 10.1186/s12879-016-1421-6
2016
Journal Article
A physiologically based kinetic model for elucidating the in vivo distribution of administered mesenchymal stem cells
Wang, Haolu, Liang, Xiaowen, Xu, Zhi Ping, Crawford, Darrell H. G, Liu, Xin and Roberts, Michael S. (2016). A physiologically based kinetic model for elucidating the in vivo distribution of administered mesenchymal stem cells. Scientific Reports, 6 (1) 22293, e22293.1-e22293.12. doi: 10.1038/srep22293
2016
Journal Article
Relative penetration of zinc oxide and zinc ions into human skin after application of different zinc oxide formulations
Holmes, Amy M., Song, Zhen, Moghimi, Hamid R. and Roberts, Michael S. (2016). Relative penetration of zinc oxide and zinc ions into human skin after application of different zinc oxide formulations. ACS Nano, 10 (2), 1810-1819. doi: 10.1021/acsnano.5b04148
2016
Journal Article
Physiologically based pharmacokinetic model for long-circulating inorganic nanoparticles
Liang, Xiaowen, Wang, Haolu, Grice, Jeffrey E., Li, Li, Liu, Xin, Xu, Zhi Ping and Roberts, Michael S. (2016). Physiologically based pharmacokinetic model for long-circulating inorganic nanoparticles. Nano Letters, 16 (2), 939-945. doi: 10.1021/acs.nanolett.5b03854
2016
Journal Article
Cardiovascular toxicity with levetiracetam overdose
Page, Colin B., Mostafa, Ahmed, Saiao, Ana, Grice, Jeffrey E., Roberts, Michael S. and Isbister, Geoffrey K. (2016). Cardiovascular toxicity with levetiracetam overdose. Clinical Toxicology, 54 (2), 152-154. doi: 10.3109/15563650.2015.1115054
2016
Journal Article
In vivo microdialysis to determine subcutaneous interstitial fluid penetration and pharmacokinetics of fluconazole in intensive care unit patients with sepsis
Sinnollareddy, Mahipal G., Roberts, Michael S., Lipman, Jeffrey, Lassig-Smith, Melissa, Starr, Therese, Robertson, Thomas, Peake, Sandra L. and Roberts, Jason A. (2016). In vivo microdialysis to determine subcutaneous interstitial fluid penetration and pharmacokinetics of fluconazole in intensive care unit patients with sepsis. Antimicrobial Agents and Chemotherapy, 60 (2), 827-832. doi: 10.1128/AAC.02461-15
2016
Book Chapter
Multiphoton and fluorescence lifetime imaging microscopy in studying nanoparticle pharmacokinetics in skin and liver
Thorling, Camilla A., Holmes, Amy, Studier, Hauke, Liu, David, Liang, Xiaowen and Roberts, Michael S. (2016). Multiphoton and fluorescence lifetime imaging microscopy in studying nanoparticle pharmacokinetics in skin and liver. Multiphoton and fluorescence lifetime imaging microscopy in studying nanoparticle pharmacokinetics in skin and liver. (pp. 107-123) edited by Stefan G. Stanciu. Rijeka, Croatia: InTech. doi: 10.5772/63452
2016
Journal Article
Zero-order metoprolol pharmacokinetics after therapeutic doses: severe toxicity and cardiogenic shock
Isbister, Geoffrey K., Ang, Karyn, Gorman, Kieron, Cooper, Joyce, Mostafa, Ahmed and Roberts, Michael S. (2016). Zero-order metoprolol pharmacokinetics after therapeutic doses: severe toxicity and cardiogenic shock. Clinical Toxicology, 54 (9), 881-885. doi: 10.1080/15563650.2016.1209768
2016
Conference Publication
Severe poisoning after ingestion of chloroform
Jayaweera, Dushan S., Islam, Shawkat A. K. M., Gunja, Naren, Cowie, Chris, Poojara, Latesh, Roberts, Michael S. and Isbister, Geoffrey K. (2016). Severe poisoning after ingestion of chloroform. ABINGDON: TAYLOR & FRANCIS LTD.
2016
Journal Article
Synergistic skin penetration enhancer and nanoemulsion formulations promote the human epidermal permeation of caffeine and naproxen
Abd, Eman, Namjoshi, Sarika, Mohammed, Yousuf H., Roberts, Michael S. and Grice, Jeffrey E. (2016). Synergistic skin penetration enhancer and nanoemulsion formulations promote the human epidermal permeation of caffeine and naproxen. Journal of Pharmaceutical Sciences, 105 (1), 212-220. doi: 10.1002/jps.24699
2016
Book Chapter
Formulation effects on topical nanoparticle penetration
Benson, H. A. E., Mohammed, Y., Grice, J. E. and Roberts, M. S. (2016). Formulation effects on topical nanoparticle penetration. Nanoscience in dermatology. (pp. 115-126) edited by Michael R. Hamblin, Pinar Avci and Tarl W. Prow. London, United Kingdom: Academic Press. doi: 10.1016/B978-0-12-802926-8.00009-4
2016
Journal Article
Short- and long-term tracking of anionic ultrasmall nanoparticles in kidney
Liang, Xiaowen, Wang, Haolu, Zhu, Yian, Zhang, Run, Cogger, Victoria C., Liu, Xin, Xu, Zhi Ping, Grice, Jeffrey E. and Roberts, Michael S. (2016). Short- and long-term tracking of anionic ultrasmall nanoparticles in kidney. Acs Nano, 10 (1), 387-395. doi: 10.1021/acsnano.5b05066
2016
Conference Publication
Using multiphoton fluorescence lifetime imaging to characterize liver damage and fluorescein disposition in liver in vivo
Thorling, Camilla A., Studier, Hauke, Crawford, Darrell H. G. and Roberts, Michael S. (2016). Using multiphoton fluorescence lifetime imaging to characterize liver damage and fluorescein disposition in liver in vivo. Multiphoton Microscopy in the Biomedical Sciences XVI, San Francisco, CA, United States, 14-16 February 2016. Bellingham, WA, United States: S P I E - International Society for Optical Engineering. doi: 10.1117/12.2235828
2015
Journal Article
A comparison of the penetration and permeation of caffeine into and through human epidermis after application in various vesicle formulations
Abd, Eman, Roberts, Michael S. and Grice, Jeffrey E. (2015). A comparison of the penetration and permeation of caffeine into and through human epidermis after application in various vesicle formulations. Skin Pharmacology and Physiology, 29 (1), 24-30. doi: 10.1159/000441040
2015
Journal Article
Optimization of dosing regimens and dosing in special populations
Sime, F. B., Roberts, M. S. and Roberts, J. A. (2015). Optimization of dosing regimens and dosing in special populations. Clinical Microbiology and Infection, 21 (10), 886-893. doi: 10.1016/j.cmi.2015.05.002
2015
Journal Article
Adequacy of high-dose cefepime regimen in febrile neutropenic patients with hematological malignancies
Sime, Fekade Bruck., Roberts, Michael S., Tiong, Ing Soo., Gardner, Julia H., Lehman, Sheila., Peake, Sandra L., Hahn, Uwe., Warner, Morgyn S. and Roberts, Jason A. (2015). Adequacy of high-dose cefepime regimen in febrile neutropenic patients with hematological malignancies. Antimicrobial Agents and Chemotherapy, 59 (9), 5463-5469. doi: 10.1128/AAC.00389-15
2015
Journal Article
The pharmacokinetics and pharmacodynamics of severe aldicarb toxicity after overdose
Michael, Adam P., Mostafa, Ahmed, Cooper, Joyce M., Grice, Jeffrey, Roberts, Michael S. and Isbister, Geoffrey K. (2015). The pharmacokinetics and pharmacodynamics of severe aldicarb toxicity after overdose. Clinical Toxicology, 53 (7), 633-635. doi: 10.3109/15563650.2015.1054504
2015
Journal Article
Acute behavioural disturbance associated with phenibut purchased via an internet supplier
Downes, Michael A., Berling, Ingrid L., Mostafa, Ahmed, Grice, Jeffrey, Roberts, Michael S. and Isbister, Geoffrey K. (2015). Acute behavioural disturbance associated with phenibut purchased via an internet supplier. Clinical Toxicology, 53 (7), 636-638. doi: 10.3109/15563650.2015.1059945
2015
Journal Article
Influence of sustained low-efficiency diafiltration (SLED-f) on interstitial fluid concentrations of fluconazole in a critically ill patient: use of microdialysis
Sinnollareddy, Mahipal G., Roberts, Michael S., Lipman, Jeffrey, Peake, Sandra L. and Roberts, Jason A. (2015). Influence of sustained low-efficiency diafiltration (SLED-f) on interstitial fluid concentrations of fluconazole in a critically ill patient: use of microdialysis. International Journal of Antimicrobial Agents, 46 (1), 121-124. doi: 10.1016/j.ijantimicag.2015.02.017
Funding
Current funding
Past funding
Supervision
Availability
- Emeritus Professor Michael Roberts is:
- Available for supervision
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Supervision history
Current supervision
-
Doctor Philosophy
Injection of Supercritical and Near-Critical Fluids into Supersonic Crossflow
Associate Advisor
Other advisors: Dr Tristan Vanyai, Professor Anand Veeraragavan
Completed supervision
-
2023
Doctor Philosophy
Development of artificial mesenchymal stem cells for hepatocellular carcinoma drug delivery
Principal Advisor
Other advisors: Dr Xin Liu, Dr Haolu Wang
-
2022
Doctor Philosophy
Pharmacotherapy consideration in hospitalized older diabetic and cardiovascular disease patients aged 75 years and above with polypharmacy
Principal Advisor
Other advisors: Dr Xin Liu, Dr Xiaowen Liang
-
2021
Doctor Philosophy
Modeling approaches to predict human skin absorption of drugs and other chemicals
Principal Advisor
Other advisors: Associate Professor Yousuf Mohammed, Dr Xin Liu
-
2019
Doctor Philosophy
Development of optimal experimental conditions for evaluation of topical products
Principal Advisor
Other advisors: Associate Professor Yousuf Mohammed, Dr Xin Liu
-
2017
Doctor Philosophy
Embedding the Clinician-Researcher Pharmacist in Healthcare
Principal Advisor
-
2016
Doctor Philosophy
An Investigation of the Pharmacokinetics of Piperacillin, Meropenem and Fluconazole in Critically Ill Obese Patients
Principal Advisor
Other advisors: Professor Jason Roberts, Professor Jeffrey Lipman
-
2015
Doctor Philosophy
Biodistribution of newly developed water-dispersible CdTe/CdS quantum dots for in vivo imaging
Principal Advisor
Other advisors: Dr Xin Liu
-
2014
Doctor Philosophy
Pharmacokinetics, Pharmacodynamics and Safety of Marbofloxacin and Trovafloxacin in Sheep
Principal Advisor
Other advisors: Dr Xin Liu
-
2014
Doctor Philosophy
Herbicide nephrotoxicity in rat and human
Principal Advisor
Other advisors: Dr Xin Liu
-
2013
Doctor Philosophy
Statin Therapy in Patients with Sepsis: From Retrospective Analysis to RCT
Principal Advisor
-
2011
Doctor Philosophy
Drug Disposition in Liver Disease: Liver histopathology and hepatic drug transporter activity as determinants of drug disposition in liver diseases
Principal Advisor
Other advisors: Dr Xin Liu
-
2010
Doctor Philosophy
The effect of resuscitation fluids on beta lactam antibiotic pharamacokinetics in interstitial tissue in acute thermal injury
Principal Advisor
Other advisors: Professor Bala Venkatesh
-
-
2006
Master Philosophy
IONTOPHORESIS OF THE NAIL
Principal Advisor
-
2006
Doctor Philosophy
AXOPLASMIC TRANSPORT AND TRANSEPIDERMAL IONTOPHORESIS: FACTORS IN NEUROGENIC PAIN MANAGEMENT
Principal Advisor
-
2005
Master Philosophy
PERCUTANEOUS PENETRATION OF PARABENS THROUGH HUMAN EPDIERMAL MEMBRANE
Principal Advisor
-
2005
Doctor Philosophy
DISPOSITION PHARMACOKINETICS AND EFFECTS OF SOLUTES AND DRUGS IN PERFUSED ORGAN SYSTEMS
Principal Advisor
-
2004
Doctor Philosophy
MEDICATION CARE: DATABASES, DRUG USE AND OUTCOMES
Principal Advisor
-
2004
Doctor Philosophy
PHARMACOEPIDEMIOLOGY OF MEDICATION USE BY THE COMMUNITY-BASED ELDERLY
Principal Advisor
-
2003
Doctor Philosophy
A COMPARISON OF THE APPROPRIATENESS OF PSYCHOTROPIC DRUG AND POLYPHARMACY USE IN MENTAL HEALTH, IN INSTITUTIONALISED PATIENTS AND IN THE COMMUNITY
Principal Advisor
-
2003
Doctor Philosophy
QUALITY OF MEDICATION CARE IN LONG TERM CARE FACILITIES: ASSESSMENT OF PROCESS, NEEDS AND TYPE OF INTERVENTION
Principal Advisor
-
2002
Doctor Philosophy
THE STUDIES OF ALCOHOLIC LIVER DISEASE (ALD): PATHOGENESIS, PHARMACOKINETICS AND THERAPEUTIC APPROACHES
Principal Advisor
-
2002
Doctor Philosophy
IDENTIFICATION AND PURIFICATION OF THE JOINT SURFACTANT PROTEINS
Principal Advisor
-
2002
Doctor Philosophy
THE EFFECT OF CHEMICAL STRUCTURE ON THE ABSORPTION OF SUNSCREENS THROUGH THE SKIN
Principal Advisor
-
2023
Doctor Philosophy
Human mesenchymal stem cell-derived liver-on-a-chip for the study of cell migration
Associate Advisor
Other advisors: Dr Kim Bridle, Dr Xiaowen Liang, Dr Haolu Wang
-
2022
Doctor Philosophy
The Characterisation of Tumour Self-Seeded Cells in Liver Cancer
Associate Advisor
Other advisors: Dr Haolu Wang, Dr Xiaowen Liang
-
2020
Doctor Philosophy
Enhanced topical drug delivery for treatment of human melanoma
Associate Advisor
Other advisors: Emeritus Professor Ross Barnard, Associate Professor Yousuf Mohammed, Associate Professor Helmut Schaider
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2019
Doctor Philosophy
Evaluation of a Ketogenic Formulation for Treating Patients with Acute Brain Injury
Associate Advisor
Other advisors: Professor Bala Venkatesh
-
2017
Doctor Philosophy
Real-time optical imaging of the liver: diagnosis and prediction of treatment response
Associate Advisor
Other advisors: Dr Xin Liu
-
2016
Doctor Philosophy
EFFECT OF TOPICAL MAGNESIUM APPLICATION ON EPIDERMAL INTEGRITY AND BARRIER FUNCTION
Associate Advisor
Other advisors: Emeritus Professor Ross Barnard
-
2016
Doctor Philosophy
Targeted skin delivery of topically applied drugs by optimised formulation design
Associate Advisor
Other advisors: Dr Xin Liu
-
2014
Master Philosophy
Development of a soluble macrolide formulation and identification of potential benefits in chronic rhinosinusitis.
Associate Advisor
-
2013
Doctor Philosophy
Particulate Penetration and Metabolic Effects in Human Skin
Associate Advisor
-
2009
Doctor Philosophy
Beta-lactam antibiotic dosing in critical care units: Bolus vs continuous dosing
Associate Advisor
Other advisors: Professor Jeffrey Lipman
-
2008
Doctor Philosophy
Depression in Parkinson's disease: assessment methods and risk factors
Associate Advisor
Other advisors: Associate Professor John O'Sullivan
-
2005
Doctor Philosophy
SURFACTANT PROTEINS IN EXTRA PULMONARY SITES
Associate Advisor
Media
Enquiries
Contact Emeritus Professor Michael Roberts directly for media enquiries about:
- Clinical pharmacology
- Drug analysis
- Drug delivery - pharmacology
- Drug structure-disposition relationships
- Health care delivery
- Hepatic metabolism
- Medication care
- Pharmacokinetics
- Pharmacology
- Topical (skin) products
- Toxicology - drugs
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