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Professor John McGrath
Professor

John McGrath

Email: 
Phone: 
+61 7 3271 8694

Overview

Background

John McGrath AM, MBBS, MD, PhD, FRANZCP, FAHMS

John McGrath is a psychiatrist interested in discovering the causes of serious mental disorders. He is the Director of the Queensland Centre for Mental Health Research and conjoint Professor at the Queensland Brain Institute His research aims to generate and evaluate nongenetic risk factors for schizophrenia. He has forged productive cross-disciplinary collaborations linking risk factor epidemiology with developmental neurobiology. For example, John and his colleagues have made discoveries linking prenatal vitamin D and later risk of mental illness in the offspring. In addition, John has supervised major systematic reviews of the epidemiology of schizophrenia. He was awarded a John Cade Fellowship by the Australian National Health and Medical Research Council. In 2016 he was also awarded a Neils Bohr Professorship by the Danish National Research Foundation.

Availability

Professor John McGrath is:
Available for supervision
Media expert

Qualifications

  • Bachelor of Medicine and Surgery and Medical Science, The University of Queensland
  • Doctor of Philosophy, The University of Queensland
  • Royal Australian and New Zealand College of Psychiatrists, Royal Australian and New Zealand College of Psychiatrists

Research interests

  • The association between vitamin D status and brain outcomes

    In collaboration with Darryl Eyles, we are measuring early life vitamin D status and exploring if this changes the risk of later developing serious mental illness. These studies are in collaboration with colleagues in Denmark, Sweden and the Netherlands.

  • The demographic and clinical correlates of psychotic-like experiences

    Using two large surveys conducted in Australia in 1997 and 2007, our group have undertaken a suite of studies designed to understand the clinical relevance of isolated psychotic-like experiences. Over recent years we have published many papers on this topic, and have made important contributions with respect to how psychotic-like experiences are associated with (a) an increased risk of later psychotic disorders (based on the MUSP study), (b) depression, anxiety and substance use disorders, (c) a family history of mental illness, (d) exposure to trauma, (e) an increased risk of suicidal ideation and behaviour, (f) general physical health, and (g) help-seeking.

  • The Survey of High Impact Psychosis (SHIP)

    Our group was one of seven sites involved in the design and administration of the second Australian Survey of psychotic disorders. In collaboration with a large national team, we continue to explore key issues related to the needs of people with psychosis in Australia.

Research impacts

The Epidemiology team are interested in the frequency measures related to serious mental disorders (e.g. incidence, prevalence, mortality, recovery/remission). We are also interested in the clinical and demographic correlates of adverse mental health outcomes – some of these may be modifiable risk factors and thus important from a public health perspective. We use large, community-based surveys, and birth cohorts. Our focus has been on psychotic disorders and psychotic-like experiences in the general population. In addition, we are examining the links between early life vitamin D status and risk of later mental illness, by directly measuring vitamin D (in collaboration with Darryl Eyles and many international collaborators).

Works

Search Professor John McGrath’s works on UQ eSpace

899 works between 1982 and 2025

281 - 300 of 899 works

2017

Journal Article

Association Between Psychotic Experiences and Subsequent Suicidal Thoughts and Behaviors: A Cross-National Analysis From the World Health Organization World Mental Health Surveys.

Bromet, Evelyn J., Nock, Matthew K., Saha, Sukanta, Lim, Carmen, Aguilar-Gaxiola, Sergio, Al-Hamzawi, Ali, Alonso, Jordi, Borge, Guilherme, Bruffaerts, Ronny, Degenhardt, Louisa, de Girolamo, Giovanni, de Jonge, Peter, Florescu, Silvia, Gureje, Oye, Haro, Josep M., He, Yanling, Hu, Chiyi, Karam, Elie G., Kovess-Masfety, Viviane, Lee, Sing, Lepine, Jean-Pierre, Mneimneh, Zeina, Navarro-Mateu, Fernando, Ojagbemi, Akin, Posada-Villa, José, Sampson, Nancy A., Scott, Kate M., Stagnaro, Juan C., Viana, Maria C. ... for the World Health Organization World Mental Health Survey Collaborators (2017). Association Between Psychotic Experiences and Subsequent Suicidal Thoughts and Behaviors: A Cross-National Analysis From the World Health Organization World Mental Health Surveys.. JAMA Psychiatry, 74 (11), 1136-1144. doi: 10.1001/jamapsychiatry.2017.2647

Association Between Psychotic Experiences and Subsequent Suicidal Thoughts and Behaviors: A Cross-National Analysis From the World Health Organization World Mental Health Surveys.

2017

Journal Article

Could lithium in drinking water reduce the incidence of dementia?

McGrath, J. J. and Berk, M. (2017). Could lithium in drinking water reduce the incidence of dementia?. JAMA Psychiatry, 74 (10), 983-984. doi: 10.1001/jamapsychiatry.2017.2336

Could lithium in drinking water reduce the incidence of dementia?

2017

Other Outputs

Causal associations between risk factors and common diseases inferred from GWAS summary data

Zhu, Zhihong, Zheng, Zhili, Zhang, Futao, Wu, Yang, Trzaskowski, Maciej, Maier, Robert, Robinson, Matthew R., McGrath, John J., Visscher, Peter M., Wray, Naomi R. and Yang, Jian (2017). Causal associations between risk factors and common diseases inferred from GWAS summary data. doi: 10.1101/168674

Causal associations between risk factors and common diseases inferred from GWAS summary data

2017

Journal Article

Developmental vitamin D deficiency alters multiple neurotransmitter systems in the neonatal rat brain

Kesby, James P., Turner, Karly M., Alexander, Suzanne, Eyles, Darryl W., McGrath, John J. and Burne, Thomas H.J. (2017). Developmental vitamin D deficiency alters multiple neurotransmitter systems in the neonatal rat brain. International Journal of Developmental Neuroscience, 62 (C), 1-7. doi: 10.1016/j.ijdevneu.2017.07.002

Developmental vitamin D deficiency alters multiple neurotransmitter systems in the neonatal rat brain

2017

Journal Article

Common mental disorders and recent physical activity status: findings from a National Community Survey

Suetani, Shuichi, Saha, Sukanta, Milad, Adam, Eakin, Elizabeth, Scott, James G. and McGrath, John J. (2017). Common mental disorders and recent physical activity status: findings from a National Community Survey. Social Psychiatry and Psychiatric Epidemiology, 52 (7), 795-802. doi: 10.1007/s00127-016-1307-3

Common mental disorders and recent physical activity status: findings from a National Community Survey

2017

Journal Article

The association between psychotic experiences and disability: results from the WHO World Mental Health Surveys

Navarro-Mateu, F., Alonso, J., Lim, C. C. W. , Saha, S. , Aguilar-Gaxiola, S. , Al-Hamzawi, A. , Andrade, L. H., Bromet, E. J., Bruffaerts, R., Chatterji, S., Degenhardt, L., de Girolamo, G., de Jonge, P., Fayyad, J., Florescu, S., Gureje, O., Haro, J. M., Hu, C., Karam, E. G., Kovess-Masfety, V., Lee, S., Medina-Mora, M. E., Ojagbemi, A., Pennell, B. -E., Piazza, M., Posada-Villa, J., Scott, K. M., Stagnaro, J. C., Xavier, M. ... McGrath, J. J. (2017). The association between psychotic experiences and disability: results from the WHO World Mental Health Surveys. Acta Psychiatrica Scandinavica, 136 (1), 74-84. doi: 10.1111/acps.12749

The association between psychotic experiences and disability: results from the WHO World Mental Health Surveys

2017

Journal Article

The role of genetic liability in the association of urbanicity at birth and during upbringing with schizophrenia in Denmark

Paksarian, D., Trabjerg, B. B., Merikangas, K. R., Mors, O., Børglum, A. D., Hougaard, D. M., McGrath, J. J., Pedersen, C. B., Mortensen, P. B. and Agerbo, E. (2017). The role of genetic liability in the association of urbanicity at birth and during upbringing with schizophrenia in Denmark. Psychological Medicine, 48 (2), 1-10. doi: 10.1017/S0033291717001696

The role of genetic liability in the association of urbanicity at birth and during upbringing with schizophrenia in Denmark

2017

Other Outputs

The iPSYCH2012 case-cohort sample: New directions for unravelling genetic and environmental architectures of severe mental disorders

Pedersen, Carsten Bøcker, Bybjerg-Grauholm, Jonas, Pedersen, Marianne Giørtz, Grove, Jakob, Agerbo, Esben, Bækvad-Hansen, Marie, Poulsen, Jesper Buchhave, Hansel, Christine Sæholm, McGrath, John J., Als, Thomas Damm, Goldstein, Jacqueline I., Neale, Ben M, Daly, Mark J, Hougaard, David M., Mors, Ole, Nordentoft, Merete, Børglum, Anders D., Werge, Thomas and Mortensen, Preben Bo (2017). The iPSYCH2012 case-cohort sample: New directions for unravelling genetic and environmental architectures of severe mental disorders. doi: 10.1101/146670

The iPSYCH2012 case-cohort sample: New directions for unravelling genetic and environmental architectures of severe mental disorders

2017

Journal Article

Vitamin D and the brain: genomic and non-genomic actions

Cui, Xiaoying, Gooch, Helen, Petty, Alice, McGrath, John J. and Eyles, Darryl (2017). Vitamin D and the brain: genomic and non-genomic actions. Molecular and Cellular Endocrinology, 453 (C), 131-143. doi: 10.1016/j.mce.2017.05.035

Vitamin D and the brain: genomic and non-genomic actions

2017

Journal Article

The association between adolescent psychopathology and subsequent physical activity in young adulthood: a 21-year birth cohort study

Suetani, S., Mamun, A., Williams, G. M., Najman, J. M., McGrath, J. J. and Scott, J. G. (2017). The association between adolescent psychopathology and subsequent physical activity in young adulthood: a 21-year birth cohort study. Psychological Medicine, 48 (2), 269-278. doi: 10.1017/S0033291717001660

The association between adolescent psychopathology and subsequent physical activity in young adulthood: a 21-year birth cohort study

2017

Journal Article

Mortality in individuals with disruptive behavior disorders diagnosed by specialist services – a nationwide cohort study

Scott, James G., Giortz Pedersen, Marianne, Erskine, Holly E., Bikic, Aida, Demontis, Ditte, McGrath, John J. and Dalsgaard, Soren (2017). Mortality in individuals with disruptive behavior disorders diagnosed by specialist services – a nationwide cohort study. Psychiatry Research, 251, 255-260. doi: 10.1016/j.psychres.2017.02.029

Mortality in individuals with disruptive behavior disorders diagnosed by specialist services – a nationwide cohort study

2017

Journal Article

The efficacy of sodium benzoate as an adjunctive treatment in early psychosis - CADENCE-BZ: study protocol for a randomized controlled trial

Ryan, Alex, Baker, Andrea, Dark, Frances, Foley, Sharon, Gordon, Anne, Hatherill, Sean, Stathis, Stephen, Saha, Sukanta, Bruxner, George, Beckman, Martin, Richardson, Drew, Berk, Michael, Dean, Olivia, McGrath, John and Scott, James (2017). The efficacy of sodium benzoate as an adjunctive treatment in early psychosis - CADENCE-BZ: study protocol for a randomized controlled trial. Trials, 18 (1) 165, 165. doi: 10.1186/s13063-017-1908-5

The efficacy of sodium benzoate as an adjunctive treatment in early psychosis - CADENCE-BZ: study protocol for a randomized controlled trial

2017

Journal Article

Years of potential life lost and life expectancy in schizophrenia: a systematic review and meta-analysis

Hjorthoj, Carsten, Sturup, Anne Emilie, McGrath, John J. and Nordentoft, Merete (2017). Years of potential life lost and life expectancy in schizophrenia: a systematic review and meta-analysis. Lancet Psychiatry, 4 (4), 295-301. doi: 10.1016/S2215-0366(17)30078-0

Years of potential life lost and life expectancy in schizophrenia: a systematic review and meta-analysis

2017

Journal Article

SA57. Life Expectancy and Years of Potential Life Lost in Schizophrenia: A Systematic Review and Meta-Analysis

Hjorthøj, Carsten, Stürup, Anne E., McGrath, John and Nordentoft, Merete (2017). SA57. Life Expectancy and Years of Potential Life Lost in Schizophrenia: A Systematic Review and Meta-Analysis. Schizophrenia Bulletin, 43 (suppl_1). doi: 10.1093/schbul/sbx023.056

SA57. Life Expectancy and Years of Potential Life Lost in Schizophrenia: A Systematic Review and Meta-Analysis

2017

Journal Article

The descriptive epidemiology of DSM-IV Adult ADHD in the World Health Organization World Mental Health Surveys

Fayyad, John, Sampson, Nancy A., Hwang, Irving, Adamowski, Tomasz, Aguilar-Gaxiola, Sergio, Al-Hamzawi, Ali, Andrade, Laura H. S. G., Borges, Guilherme, de Girolamo, Giovanni, Florescu, Silvia, Gureje, Oye, Maria Haro, Josep, Hu, Chiyi, Karam, Elie G., Lee, Sing, Navarro-Mateu, Fernando, O'Neill, Siobhan, Pennell, Beth-Ellen, Piazza, Marina, Posada-Villa, Jose, ten Have, Margreet, Torres, Yolanda, Xavier, Miguel, Zaslavsky, Alan M., Kessler, Ronald C., on behalf of the WHO World Mental Health Survey Collaborators and McGrath, John J. (2017). The descriptive epidemiology of DSM-IV Adult ADHD in the World Health Organization World Mental Health Surveys. Adhd-Attention Deficit and Hyperactivity Disorders, 9 (1), 47-65. doi: 10.1007/s12402-016-0208-3

The descriptive epidemiology of DSM-IV Adult ADHD in the World Health Organization World Mental Health Surveys

2017

Journal Article

Gestational vitamin D deficiency and autism spectrum disorder

Vinkhuyzen, Anna A. E., Eyles, Darryl W., Burne, Thomas H. J., Blanken, Laura M. E., Kruithof, Claudia J., Verhulst, Frank, White, Tonya, Jaddoe, Vincent W., Tiemeier, Henning and McGrath, John J. (2017). Gestational vitamin D deficiency and autism spectrum disorder. BJPsych Open, 3 (2), 85-90. doi: 10.1192/bjpo.bp.116.004077

Gestational vitamin D deficiency and autism spectrum disorder

2017

Journal Article

Vitamin D and mental health - the scrutiny of science delivers a sober message

McGrath, J. J. (2017). Vitamin D and mental health - the scrutiny of science delivers a sober message. Acta Psychiatrica Scandinavica, 135 (3), 183-184. doi: 10.1111/acps.12708

Vitamin D and mental health - the scrutiny of science delivers a sober message

2017

Conference Publication

LIFE EXPECTANCY AND YEARS OF POTENTIAL LIFE LOST IN SCHIZOPHRENIA: A SYSTEMATIC REVIEW AND META-ANALYSIS

Hjorthoj, Carsten, Sturup, Anne E., McGrath, John and Nordentoft, Merete (2017). LIFE EXPECTANCY AND YEARS OF POTENTIAL LIFE LOST IN SCHIZOPHRENIA: A SYSTEMATIC REVIEW AND META-ANALYSIS. 16th International Congress on Schizophrenia Research (ICOSR), San Diego Ca, Mar 24-28, 2017. OXFORD: OXFORD UNIV PRESS.

LIFE EXPECTANCY AND YEARS OF POTENTIAL LIFE LOST IN SCHIZOPHRENIA: A SYSTEMATIC REVIEW AND META-ANALYSIS

2017

Journal Article

Association of DSM-IV posttraumatic stress disorder with traumatic experience type and history in the World Health Organization World Mental Health surveys

Liu, Howard, Petukhova, Maria V., Sampson, Nancy A., Aguilar-Gaxiola, Sergio, Alonso, Jordi, Andrade, Laura Helena, Bromet, Evelyn J., De Girolamo, Giovanni, Haro, Josep Maria, Hinkov, Hristo, Kawakami, Norito, Koenen, Karestan C., Kovess-Masfety, Viviane, Lee, Sing, Medina-Mora, Maria Elena, Navarro-Mateu, Fernando, O'Neill, Siobhan, Piazza, Marina, Posada-Villa, José, Scott, Kate M., Shahly, Victoria, Stein, Dan J., Ten Have, Margreet, Torres, Yolanda, Gureje, Oye, Zaslavsky, Alan M., Kessler, Ronald C., Al-Hamzawi, Ali, Al-Kaisy, Mohammed Salih ... Wojtyniak, Bogdan (2017). Association of DSM-IV posttraumatic stress disorder with traumatic experience type and history in the World Health Organization World Mental Health surveys. JAMA Psychiatry, 74 (3), 270-281. doi: 10.1001/jamapsychiatry.2016.3783

Association of DSM-IV posttraumatic stress disorder with traumatic experience type and history in the World Health Organization World Mental Health surveys

2017

Journal Article

Risk of psychiatric illness from advanced paternal age is not predominantly from de novo mutations

Gratten, Jacob, Wray, Naomi R., Peyrot, Wouter J., McGrath, John J., Visscher, Peter M. and Goddard, Michael E. (2017). Risk of psychiatric illness from advanced paternal age is not predominantly from de novo mutations. Obstetrical and Gynecological Survey, 72 (2), 96-96. doi: 10.1097/01.OGX.0000512485.13448.C7

Risk of psychiatric illness from advanced paternal age is not predominantly from de novo mutations

Funding

Current funding

  • 2021 - 2027
    Mental Health Australia General Clinical Trial Network (MAGNET) (MRFF Million Minds Mental Health Research Grant Led by Deakin University)
    Deakin University
    Open grant

Past funding

  • 2019 - 2023
    CREDIT: The CRE for the Development of Innovative Therapies for Psychiatric Disorders (NHMRC CRE administered by Deakin University)
    NHMRC Centres of Research Excellence
    Open grant
  • 2018 - 2022
    Developmental Vitamin D-deficiency and Autism; exploration of potential mechanisms and refining phenotype in an animal model
    NHMRC Project Grant
    Open grant
  • 2017 - 2019
    A comparison study of three physical activity measurement tools examining acceptability in people with psychotic disorders
    Society for Mental Health Research Inc
    Open grant
  • 2017 - 2022
    An Integrated Program of Psychiatric Epidemiology (IPPE)
    Aarhus University
    Open grant
  • 2017
    Voltage-gated calcium channels and vitamin D: investigating the convergent links between risk factors for schizophrenia
    RL Cooper Medical Research Foundation Limited
    Open grant
  • 2016 - 2019
    The efficacy of adjunctive Garcinia mangostana Linn (mangosteen) pericarp for the treatment of Schizophrenia: A double-blind, randomized, placebo controlled trial (SMRI grant admin. by Deakin Uni)
    Deakin University
    Open grant
  • 2016 - 2017
    World Mental Health Survey
    University of Otago
    Open grant
  • 2016 - 2020
    An empirical framework for assessing mortality and morbidity in people with psychotic disorders (NHMRC Project Grant administered by the University of Western Australia)
    University of Western Australia
    Open grant
  • 2016 - 2020
    Voltage gated calcium channels and vitamin D: exploring the convergent links between risk factors for schizophrenia
    NHMRC Project Grant
    Open grant
  • 2015
    A sensitive, high resolution QTOF mass spectrometer with nanoUPLC system for qualitative and quantitative biomolecule analysis.
    UQ Major Equipment and Infrastructure
    Open grant
  • 2015 - 2018
    Does adult vitamin D deficiency increase vulnerability to social stress resulting in altered brain function?
    NHMRC Project Grant
    Open grant
  • 2014 - 2016
    Early life vitamin D levels and risk of autism spectrum disorders (NIH grant administered by Drexel University)
    Drexel University
    Open grant
  • 2014 - 2017
    Is developmental vitamin D deficiency associated with autism-related phenotypes: a birth cohort study
    NHMRC Project Grant
    Open grant
  • 2014 - 2017
    Vitamin D in first episode psychosis - neuroprotective design (D-FEND)
    Stanley Medical Research Institute
    Open grant
  • 2013 - 2018
    NHMRC John Cade Fellowship in Mental Health: Modifiable risk factors for Serious Mental Illness - an integrated program of epidemiology, genetics and clinical trials
    NHMRC Targeted Research
    Open grant
  • 2013 - 2016
    Early pharmacological intervention in an animal model of schizophrenia
    NHMRC Project Grant
    Open grant
  • 2013 - 2016
    Exploring modifiable candidate risk factors for mental illness in young adults: Infection, vitamin D and stress (NHMRC Project Grant administered by QIMR)
    Queensland Institute of Medical Research
    Open grant
  • 2013 - 2015
    The outcomes of adolescents and young adults who experience hallucinations: A birth cohort study
    NHMRC Project Grant
    Open grant
  • 2012 - 2024
    Developmental Neurobiology of Vitamin D Deficiency Program Funding
    West Moreton Hospital and Health Service
    Open grant
  • 2012
    Developmental Neurobiology Programme Funding
    Queensland Health
    Open grant
  • 2012 - 2015
    Developmental vitamin D deficiency and prefrontal cortical dysfunction
    NHMRC Project Grant
    Open grant
  • 2011
    Advanced behavioural facility
    UQ Major Equipment and Infrastructure
    Open grant
  • 2011 - 2014
    Attentional processing in developmentally vitamin D deficient rats: Modelling the cognitive symptoms of schizophrenia
    NHMRC Project Grant
    Open grant
  • 2011 - 2013
    Neonatal vitamin D status and risk of schizophrenia: a replication in two independent samples
    NHMRC Project Grant
    Open grant
  • 2009 - 2012
    Advanced paternal age: behavioural, neuroanatomical and genomic correlates in the offspring of older fathers
    NHMRC Project Grant
    Open grant
  • 2009 - 2011
    Physiological and neurochemical mechanisms of executive control
    NHMRC Project Grant
    Open grant
  • 2008 - 2009
    Facility for analysing behaviour, learning and motor skills in animal models
    ARC Linkage Infrastructure, Equipment and Facilities
    Open grant
  • 2007
    Is adult neurogenesis in schizophrenia altered? A pilot study using 14C dating of post-mortem neuronal DNA
    Australian Institute of Nuclear Science and Engineering
    Open grant
  • 2007 - 2009
    Neonatal vitamin D status and risk of schizophrenia: a study using Danish dried bloods spots
    NHMRC Project Grant
    Open grant
  • 2007 - 2009
    The Developmental vitamin D model (DVD) as an animal model for schizophrenia
    NHMRC Project Grant
    Open grant
  • 2005 - 2012
    QCMHR Operational (Developmental Neurobiology Programme Funding)
    Queensland Health
    Open grant
  • 2004 - 2008
    Epidemiology Research Project
    Queensland Health
    Open grant
  • 2003 - 2005
    Linking clinical and basic research in order to understand the causes of schizophrenia: a collaborative network to study animal models of schizophrenia
    Neuroscience Institute of Schizophrenia Allied Disorders Ltd.
    Open grant
  • 2003 - 2004
    Developmental neurobiology
    Queensland Centre for Schizophrenia Research
    Open grant
  • 2003 - 2006
    Structural And Diffusion Tensor Neuroimaging In Twins Concordant And Discordant For Psychosis
    NHMRC Project Grant
    Open grant
  • 2000 - 2010
    QCMHR Operational (Developmental Neuroscience Laboratory Support)
    Queensland Health
    Open grant
  • 1998 - 2006
    An integrated research program examining risk factors for psychoses
    Stanley Foundation Research Awards Program
    Open grant
  • 1998
    Evoked Response Potential (ERP) and Behavioural Correlates of Working Memory in Psychoses
    Mayne Bequest Fund
    Open grant
  • 1998
    The assessment of functioning in families with a parent who has serious mental illness
    Australian Rotary Health Research Fund
    Open grant
  • 1998
    The assessment of motor and executive skills in infants at high risk for psychoses: a pilot study
    Ross U.C.V. Bequest
    Open grant
  • 1997 - 2013
    QCMHR Operational (Collaborative Research Projects Support)
    Queensland Health
    Open grant
  • 1996 - 1997
    Impact of clozapine
    Queensland Health
    Open grant
  • 1996 - 1997
    Impact of clozapine
    Wolston Park Hospital
    Open grant
  • 1996 - 1998
    Promoting positive outcomes for parents with serious mental illness
    Queensland Health Health Promotion
    Open grant
  • 1996 - 1999
    A survey of the needs of parents with serious psychiatric disorders
    Department Health & Family Services - RADGAC
    Open grant
  • 1996 - 1997
    The associations between working memory and the symptoms of schizophrenia
    ARC Australian Research Council (Small grants)
    Open grant

Supervision

Availability

Professor John McGrath is:
Available for supervision

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Supervision history

Completed supervision

Media

Enquiries

Contact Professor John McGrath directly for media enquiries about:

  • Brain development
  • Neuroscience
  • Schizophrenia

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