
Overview
Background
Judith Greer is an immunologist with a strong interest in the nervous system and autoimmune diseases affecting the nervous system.
She is a graduate of the University of Queensland, having completed her PhD on cancer immunology. She then undertook postdoctoral training at Harvard Medical School in the USA, during which time her interests shifted towards immune responses and interactions within the nervous system (neuroimmunology), an area in which she has worked ever since. She isa Principal Research Fellow at the UQ Centre for Clinical Research, located at the Royal Brisbane & Women's Hospital.
Her research is directly particularly towards trying to identify brain components that are targetted by the immune system in people with a variety of disorders, particularly multiple sclerosis (MS), which is traditionally thought to be an autoimmune disease, but also in psychosis, where we are now starting to understand that autoimmune targetting of the brain can play a role in some patients. She is interested in how the specificity of autoimmune responses within the nervous system relates to the symptoms experienced by patients, and in developing new ways to specifically turn off the damaging immune responses in the brain. Another focus of her research is to improve on pre-clinical models of MS, so as to enhance the translation of new therapeutic approaches for MS to the clinic.
Judith is also interested in research training, and held leadership positions in this area in the School of Medicine and the Faculty of Medicine at UQ from 2000 - 2023. She is also committed to improving the field of neuroimmunology, and has been a member of the International Advisory Board of the International Society for Neuroimmunology and is the Asia-Pacific representative for the Global Schools of Neuroimmunology. Judith co-founded a society, Neuroimmunology Australia, to better support those working in this field, and was Convenor and Chair of the 14th International Congress of Neuroimmunology, which was held in Brisbane in 2018 (the only time this congress has been held outside of the Northern Hemisphere).
Availability
- Associate Professor Judith Greer is:
- Not available for supervision
Fields of research
Qualifications
- Bachelor (Honours) of Science (Advanced), The University of Queensland
- Doctor of Philosophy of Tumour Immunology, The University of Queensland
- Foreign Fellow, American Association of Immunologists, American Association of Immunologists
- Foreign Fellow, American Society for Neurochemistry, American Society for Neurochemistry
- Board Member, Australian and New Zealand Society for Immunology, Australian and New Zealand Society for Immunology
- Journal Editorial Board Member, Frontiers in Immunology, Frontiers in Immunology
- Journal Editorial Board Member, Immunology & Cell Biology, Immunology & Cell Biology
- Board Member, International Society of Neuroimmunology, International Society of Neuroimmunology
- Journal Editorial Board Member, Journal of Clinical Medicine, Journal of Clinical Medicine
- Journal Editorial Board Member, Journal of Immunology, Journal of Immunology
- Journal Editorial Board Member, Journal of Neuroimmunology, Journal of Neuroimmunology
- Board Member, Neuroimmunology Australia, Neuroimmunology Australia
Research interests
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Immunology of multiple sclerosis
My main research interest is in multiple sclerosis, an autoimmune disease affecting the central nervous system. I am interested in how we can determine the antigen specificity of the autoimmune response and how we might target this in a specific manner to treat the disease.
Works
Search Professor Judith Greer’s works on UQ eSpace
2012
Conference Publication
Quantitative analysis of the spinal cord CD4+T lymphocyte proteome in EAE
McColl, S.R., Turvey, M., Koudelka, T., Carroll, W., Bernard, C., Greer, J., Hoffmann, P. and MSRA Proteomics Platform (2012). Quantitative analysis of the spinal cord CD4+T lymphocyte proteome in EAE. Progress in MS Research Conference 2011, Melbourne, VIC, Australia, 26-28 October 2011. London, United Kingdom: Sage Publications. doi: 10.1177/1352458512440394
2012
Conference Publication
Improving efficacy of antigen-specific therapeutic agents in an animal model of multiple sclerosis
Greer, Judith, Moxey, Nancy, Beaino, Wissam and Trifilieff, Elisabeth (2012). Improving efficacy of antigen-specific therapeutic agents in an animal model of multiple sclerosis. 11th International Congress of Neuroimmunology (ISNI), Boston MA., United States, 4-8 November 2012. Amsterdam, The Netherlands: Elsevier.
2011
Journal Article
Levels of phosphorylated axonal neurofilament subunit H (pNfH) are increased in acute ischemic stroke
Singh, P., Yan, J., Hull, R., Read, S., O'Sullivan, J., Henderson, R.D., Rose, S., Greer, J.M. and McCombe, P.A. (2011). Levels of phosphorylated axonal neurofilament subunit H (pNfH) are increased in acute ischemic stroke. Journal of the Neurological Sciences, 304 (1-2), 117-121. doi: 10.1016/j.jns.2011.01.025
2011
Journal Article
Comparing genotyping algorithms for Illumina's Infinium whole-genome SNP BeadChips
Ritchie, Matthew E., Liu, Ruijie, Carvalho, Benilton S., The Australia and New Zealand Multiple Sclerosis Genetics Consortium (ANZgene), Irizarry, Rafael A., Brown, Matthew A., Csurhes, Peter A., Danoy, Patrick, Greer, Judith M., Hadler, Johanna, Pryce, Karena and Pender, Michael P. (2011). Comparing genotyping algorithms for Illumina's Infinium whole-genome SNP BeadChips. BMC Bioinformatics, 12 (4) 68, 68.1-68.12. doi: 10.1186/1471-2105-12-68
2011
Journal Article
Modeling the cumulative genetic risk for multiple sclerosis from genome-wide association data.
Wang, Joanne H., Pappas, Derek, De Jager, Philip L., Pelletier, Daniel, de Bakker, Paul I. W., Kappos, Ludwig, Polman, Chris H., The Australian and New Zealand Multiple Sclerosis Genetics Consortium, Bahlo, Melanie, Booth, David R., Broadley, Simon A., Brown, Matthew A., Foote, Simon J., Griffiths, Lyn R., Kilpatrick, Trevor J., Lechner-Scott, Jeanette, Moscato, Pablo, Perreau, Victoria M., Rubio, Justin P., Scott, Rodney J., Stankovich, Jim, Stewart, Graeme J., Taylor, Bruce V., Wiley, James, Danoy, Patrick, Butzkueven, Helmut, Slee, Mark, Greer, Judith M., Kermode, Allan ... Oksenberg, Jorge R. (2011). Modeling the cumulative genetic risk for multiple sclerosis from genome-wide association data.. Genome Medicine, 3 (1) 3, 3.1-3.10. doi: 10.1186/gm217
2010
Journal Article
Investigation of the [-/A](8) and C1236T genetic variations within the human toll-like receptor 3 gene for association with multiple sclerosis
Szvetko, Attila, Jones, Ashleigh, Mackenzie, Jason, Tajouri, Lotti, Csurhes, Peter, Greer, Judith, Pender, Michael and Griffiths, Lyn (2010). Investigation of the [-/A](8) and C1236T genetic variations within the human toll-like receptor 3 gene for association with multiple sclerosis. Neurological Research [electronic resource], 32 (4), 438-441. doi: 10.1179/174313209X405155
2010
Journal Article
The effect of ageing on human lymphocyte subsets: comparison of males and females
Yan, Jun, Greer, Judith M., Hull, Renee, O'Sullivan, John D., Henderson, Robert D., Read, Stephen J. and McCombe, Pamela A. (2010). The effect of ageing on human lymphocyte subsets: comparison of males and females. Immunity & Ageing, 7 (4) 1742, 1-10. doi: 10.1186/1742-4933-7-4
2010
Journal Article
Saliva-derived DNA performs well in large-scale, high-density single-nucleotide polymorphism microarray studies
Bahlo, Melanie, Stankovich, Jim, Danoy, Patrick, Hickey, Peter F., Taylor, Bruce V., Browning, Sharon R., The Australian and New Zealand Multiple Sclerosis Genetics Consortium (ANZgene), Brown, Matthew A., Rubio, Justin P., Csurhes, Peter A., Greer, Judith, Pender, Michael P. and Pryce, Karena (2010). Saliva-derived DNA performs well in large-scale, high-density single-nucleotide polymorphism microarray studies. Cancer Epidemiology, Biomarkers and Prevention, 19 (3), 794-798. doi: 10.1158/1055-9965.EPI-09-0812
2010
Conference Publication
Elevated levels of autoantibodies against neurotransmitter receptor-related molecules in schizophrenia
Jones, Amanda, Mowry, Bryan, Pender, Michael and Greer, Judith (2010). Elevated levels of autoantibodies against neurotransmitter receptor-related molecules in schizophrenia. 10th Congress of the International-Society-of-Neuroimmunology (ISNI), Sitges SPAIN, OCT 26-30, 2010.
2010
Conference Publication
Enhancing protective effects of modified peptides for treatment of multiple sclerosis
Moxey, Nancy, Trifilieff, Elisabeth and Greer, Judith (2010). Enhancing protective effects of modified peptides for treatment of multiple sclerosis. 10th Course of the European School of Neuroimmunology, Sitges, Spain, 26-30 October 2010. Amsterdam, Netherlands: Elsevier. doi: 10.1016/j.jneuroim.2010.08.001
2010
Conference Publication
Role of antibody and complement in determining site of lesion development in an animal model of multiple sclerosis
Greer, Judith and Muller, Diane (2010). Role of antibody and complement in determining site of lesion development in an animal model of multiple sclerosis. 2010 10th Course of the European School of Neuroimmunology, Sitges, Spain, 26-30 October 2010. Amsterdam, Netherlands: Elsevier.
2009
Journal Article
Sexual dimorphism in autoimmune disease
McCombe, P.A., Greer, J.M. and Mackay, I.R. (2009). Sexual dimorphism in autoimmune disease. Current Molecular Medicine, 9 (9), 1058-1079. doi: 10.2174/156652409789839116
2009
Journal Article
Genome-wide association study identifies new multiple sclerosis susceptibility loci on chromosomes 12 and 20
Bahlo, Melanie, Booth, David R., Broadley, Simon A., Brown, Matthew A., Foote, Simon J., Griffiths, Lyn R., Kilpatrick, Trevour J., Lechner-Scott, Jeanette, Moscato, Pablo, Perreau, Victoria M., Rubio, Justin P., Scott, Rodney J., Stankovich, Jim, Stewart, Graeme J., Taylor, Bruce V., Wiley, James, Clarke, Glynnis, Cox, Mathew B., Csurhes, Peter A., Danoy, Patrick, Drysdale, Karen, Field, Judith, Foote, Simon J., Greer, Judith M., Griffiths, Lyn R, Hadler, Johanna, McMorran, Brendan J., Jensen, Cathy J., Johnson, Laura J. ... Willoughby, Ernest (2009). Genome-wide association study identifies new multiple sclerosis susceptibility loci on chromosomes 12 and 20. Nature Genetics, 41 (7), 824-828. doi: 10.1038/ng.396
2009
Journal Article
HLA-DRB1 associations with disease susceptibility and clinical course in australians with multiple sclerosis
Stankovich, J., Butzkueven, H., Marriott, M., Chapman, C., Tubridy, N., Tait, B.D., Varney, M.D., Taylor, B.V., Foote, S.J., Booth, D.R., Broadley, S., Greer, J.M., Griffiths, L.R., Heard, R.N., Lechner-Scott, M.J., Pender, M.J., Scott, R.J. and Stewart, G.J. (2009). HLA-DRB1 associations with disease susceptibility and clinical course in australians with multiple sclerosis. Tissue Antigens, 74 (1), 17-21. doi: 10.1111/j.1399-0039.2009.01262.x
2009
Journal Article
Prominent brainstem and cerebellar involvement in multiple sclerosis with psoriasis
Ganesvaran, G., Greer, J. M. and Pender, M. P. (2009). Prominent brainstem and cerebellar involvement in multiple sclerosis with psoriasis. Multiple Sclerosis, 15 (6), 763-766. doi: 10.1177/1352458509103612
2009
Journal Article
Study of leukemia inhibitory factor polymorphism within an Australian multiple sclerosis population
Mackenzie, Jason, Tajouri, Lotti, Szvetko, Attila, Weth, Verena, Moreau, Julie, Greer, Judith M., Csurhes, Peter A., Pender, Michael P. and Griffiths, Lyn R. (2009). Study of leukemia inhibitory factor polymorphism within an Australian multiple sclerosis population. Journal of the Neurological Sciences, 280 (1-2), 62-64. doi: 10.1016/j.jns.2009.01.026
2009
Journal Article
CTLA-4 single-nucleotide polymorphisms in a Caucasian population with schizophrenia
Jones, Amanda L., Holliday, Elizabeth G., Mowry, Bryan J., McLean, Duncan E., McGrath, John J., Pender, Michael P. and Greer, Judith M. (2009). CTLA-4 single-nucleotide polymorphisms in a Caucasian population with schizophrenia. Brain Behavior and Immunity, 23 (3), 347-350. doi: 10.1016/j.bbi.2008.09.008
2009
Journal Article
An investigation of the C77G and C772T variations within the human protein tyrosine phosphatase receptor type C gene for association with multiple sclerosis in an Australian population
Szvetko, Attila L., Jones, Ashleigh, Mackenzie, Jason, Tajouri, Lotti, Csurhes, Peter A., Greer, Judith M., Pender, Michael P. and Griffiths, Lyn R. (2009). An investigation of the C77G and C772T variations within the human protein tyrosine phosphatase receptor type C gene for association with multiple sclerosis in an Australian population. Brain Research, 1255, 148-152. doi: 10.1016/j.brainres.2008.12.017
2009
Journal Article
Immune activation in the peripheral blood of patients with acute ischemic stroke
Yan, Jun, Greer, Judith M., Etherington, Kellie, Cadigan, Greg P., Cavanagh, Helen, Henderson, Robert D., O'Sullivan, John D., Pandian, Jeyaraj D., Read, Stephen J. and McCombe, Pamela A. (2009). Immune activation in the peripheral blood of patients with acute ischemic stroke. Journal of Neuroimmunology, 206 (1-2), 112-117. doi: 10.1016/j.jneuroim.2008.11.001
2008
Conference Publication
Role of autoreactivity against myelin proteolipid protein in multiple sclerosis
Greer, Judith, Csurhes, Peter, Muller, Diane and Pender, Michael (2008). Role of autoreactivity against myelin proteolipid protein in multiple sclerosis. ISNI 2008: 9th International Congress of Neuroimmunology, Fort Worth, TX, U.S.A., October 26-30, 2008. Amsterdam, Netherlands: Elsevier. doi: 10.1016/j.jneuroim.2008.08.001
Funding
Current funding
Past funding
Supervision
Availability
- Associate Professor Judith Greer is:
- Not available for supervision
Supervision history
Current supervision
-
Doctor Philosophy
A novel humanized mouse model for multiple sclerosis
Principal Advisor
-
Doctor Philosophy
The role of Epstein-Barr virus infection in multiple sclerosis
Principal Advisor
Other advisors: Professor Pamela McCombe
-
Doctor Philosophy
A novel humanized mouse model for multiple sclerosis
Principal Advisor
Other advisors: Dr Aakanksha Dixit
-
Doctor Philosophy
Investigation of the role of BTK and NF-kB signalling in CNS cells
Principal Advisor
Completed supervision
-
2022
Doctor Philosophy
Anti-Muscarinic Acetylcholine Receptor Antibodies in First Episode Psychosis
Principal Advisor
Other advisors: Professor James Scott
-
2022
Doctor Philosophy
Investigating the mechanism of action of a novel therapeutic derived from parasitic worms in animal models of multiple sclerosis
Principal Advisor
-
2015
Doctor Philosophy
Amino acid variants of myelin proteolipid protein: potential inducers of multiple sclerosis or potential means to a cure?
Principal Advisor
Other advisors: Emeritus Professor Michael Pender
-
2013
Doctor Philosophy
Altered peptide ligands as therapeutic agents for a model of multiple sclerosis: Determining the signature of clinical efficacy
Principal Advisor
Other advisors: Emeritus Professor Michael Pender
-
2012
Doctor Philosophy
Immune dysregulation in schizophrenia: Do some cases of schizophrenia have an autoimmune basis?
Principal Advisor
Other advisors: Emeritus Professor Michael Pender, Professor Bryan Mowry
-
2012
Doctor Philosophy
Neuropathological and Neuroimmunological Studies of the Central Nervous System of Mice With Axial-Rotatory Experimental Autoimmune Encephalomyelitis
Principal Advisor
Other advisors: Emeritus Professor Michael Pender
-
2007
Doctor Philosophy
Development of immunomodulatory peptides for the treatment of the experimental autoimmune encephalomyelitis (EAE), an animal model of multiple sclerosis
Principal Advisor
-
2014
Doctor Philosophy
Pathogenesis of Guillain-Barre syndrome and chronic inflammatory polyradiculoneuropathy
Associate Advisor
Other advisors: Professor Pamela McCombe
-
2007
Doctor Philosophy
EXAMINATION OF SURFACE-RECORDED MOTOR UNITS AND A NEW APPROACH TO MOTOR UNIT NUMBER ESTIMATES
Associate Advisor
Other advisors: Professor Pamela McCombe
-
2003
Doctor Philosophy
MITOCHONDRIAL IRON METABOLISM AND THE ROLE OF FRATAXIN IN IRON AND HAEM METABOLISM
Associate Advisor
Media
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